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Difference between revisions of "Reference state"

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{{MitoPedia
{{MitoPedia
|abbr=''Z''
|abbr=''Z''
|description=The '''reference sate''', ''Z'' is the respiratory state with stimulated or un-inhibited, high flux, in relation to the [[background state]], ''Y''.
|description=The '''reference state''' Z (reference rate ''Z<sub>X</sub>'') is the respiratory state with high flux in relation to the [[background state]] Y with low background flux ''Y<sub>X</sub>''. The transition between the background state and the reference state is a step brought about by a [[metabolic control variable]] ''X''. If ''X'' stimulates flux (ADP, fuel substrate), it is present in the reference state but absent in the background state. If ''X'' is an inhibitor of flux, it is absent in the reference state but present in the background state. The reference state is specific for a single step to define the [[flux control efficiency]]. In contrast, in a sequence of multiple steps, the common reference state is frequently taken as the state with the highest flux in the entire sequence, as used in the definition of the [[flux control ratio]].
|info=[[Gnaiger 2013 Abstract MiP2013]]
|info=[[Flux control efficiency]], [[Flux control ratio]]
}}
}}
{{MitoPedia methods
Communicated by [[Gnaiger Erich]] (2013-08-01) last update 2020-11-10.
|mitopedia method=Respirometry
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{{MitoPedia concepts
|mitopedia concept=Respiratory state, Recommended
}}
}}
{{MitoPedia topics
{{MitoPedia topics
|mitopedia topic=Respiratory state
|mitopedia topic=EAGLE
}}
}}

Latest revision as of 17:14, 10 November 2020


high-resolution terminology - matching measurements at high-resolution


Reference state

Description

The reference state Z (reference rate ZX) is the respiratory state with high flux in relation to the background state Y with low background flux YX. The transition between the background state and the reference state is a step brought about by a metabolic control variable X. If X stimulates flux (ADP, fuel substrate), it is present in the reference state but absent in the background state. If X is an inhibitor of flux, it is absent in the reference state but present in the background state. The reference state is specific for a single step to define the flux control efficiency. In contrast, in a sequence of multiple steps, the common reference state is frequently taken as the state with the highest flux in the entire sequence, as used in the definition of the flux control ratio.

Abbreviation: Z

Reference: Flux control efficiency, Flux control ratio

Communicated by Gnaiger Erich (2013-08-01) last update 2020-11-10.


MitoPedia concepts: Respiratory state, Recommended 


MitoPedia topics: EAGLE