Sample

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Sample

Description

A sample is one or more parts taken from a system and intended to provide information on the system, often to serve as a basis for evaluation of the system (diagnosis) or for a decision on intervention (therapy, production process). Compare: Primary sample.

Reference: ISO 15189:2012 Medical laboratories — Particular requirements for quality and competence

MitoPedia concepts: "MitoFit Quality Control System" is not in the list (MiP concept, Respiratory state, Respiratory control ratio, SUIT concept, SUIT protocol, SUIT A, SUIT B, SUIT C, SUIT state, Recommended, ...) of allowed values for the "MitoPedia concept" property. MitoFit Quality Control System"MitoFit Quality Control System" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property. 

MitoPedia topics: Sample preparation 

MitoFit Quality Control System

Contributed by Gnaiger E 2016-01-27; last update 2016-05-28.

Sample and sample type

A sample of a defined sample type subjected to a specific sample preparation (see MitoPedia: Sample preparations) may be e.g. a mitochondrial preparation obtained from an organ, cells suspended from a cell culture dish, a tissue biopsy, an organ, an individual organism, or a group of organisms (e.g. a number of nematodes studied collectively in an experimental chamber).

Example: Sample and subsample

A blood sample or a biopsy taken from an individual organism. The sample size, N, corresponds to the number replica, e.g. N organisms in a study group (arm). A sample may be processed and split into a number of subsamples (e.g. smaller volumes of serum taken from a larger volume of serum) for (i) application of different types of assay, and (ii) a number of repetitions, n, of the same assay on the same sample.