Schmitt Sabine

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Name Schmitt Sabine, PhD
Institution
Sabine Schmitt

Chief Technology Officer (CTO), Mitochondrial Detective

Oroboros Instruments

Sabine Schmitt joined Oroboros Instruments in April 2020 and was a visiting scientist at Oroboros Instruments within the Secondment MtFOIE GRAS.

Address Schöpfstraße 18, 6020
City Innsbruck
State/Province
Country Austria
Email sabine.schmitt@oroboros.at
Weblink
O2k-Network Lab AT Innsbruck Oroboros, DE Munich Zischka H


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Publications

 PublishedReference
EBEC2024 Abstract Book 2024 Biochim Biophys Acta Bioenerg2024Tindle-Solomon L, Schmitt S, Gnaiger C, Cardoso LHD, Gnaiger E, eds (2024) EBEC2024 Abstract Book. Biochim Biophys Acta – Bioenergetics. 1865S:1–156.
EBEC2024 Bioenerg Commun2024Tindle-Solomon L, Schmitt S, Gnaiger C, Cardoso LHD, Cocco P, Gnaiger E, eds (2024) EBEC2024 Late-breaking abstracts. Bioenerg Commun 2024.6. https://doi.org/10.26124/bec.2024-0006
Donnelly 2022 BEC2022Donnelly C, Schmitt S, Cecatto C, Cardoso LHD, Komlódi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioenerg Commun 2022.12.v2. https://doi.org/10.26124/bec:2022-0012.v2
Kabiri 2021b Methods Mol Biol2021Kabiri Y, Eberhagen C, Schmitt S, Knolle PA, Zischka H (2021) Isolation and Electron Microscopic Analysis of Liver Cancer Cell Mitochondria. Methods Mol Biol 2277:277-287.
BEC 2020.1 doi10.26124bec2020-0001.v12020Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1
Meßner 2020 FASEB J2020Meßner M, Schmitt S, Ardelt MA, Fröhlich T, Müller M, Pein H, Huber-Cantonati P, Ortler C, Koenig LM, Zobel L, Koeberle A, Arnold GJ, Rothenfußer S, Kiemer AK, Gerbes AL, Zischka H, Vollmar AM, Pachmayr J (2020) Metabolic implication of tigecycline as an efficacious second-line treatment for sorafenib-resistant hepatocellular carcinoma. FASEB J 34:11860-82.
Fessler 2020 Nature2020Fessler E, Eckl EM, Schmitt S, Mancilla IA, Meyer-Bender MF, Hanf M, Philippou-Massier J, Krebs S, Zischka H, Jae LT (2020) A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol. Nature 579:433-437.
Blecha 2017 Free Radic Biol Med2017Blecha J, Novais SM, Rohlenova K, Novotna E, Lettlova S, Schmitt S, Zischka H, Neuzil J, Rohlena J (2017) Antioxidant defense in quiescent cells determines selectivity of electron transport chain inhibition-induced cell death. Free Radic Biol Med 112:253-66.
Schmitt 2015 Methods Mol Biol2015Schmitt S, Eberhagen C, Weber S, Aichler M, Zischka H (2015) Isolation of mitochondria from cultured cells and liver tissue biopsies for molecular and biochemical analyses. Methods Mol Biol 1295:87-97.
Schmitt 2013 Anal Biochem2013Schmitt S, Saathoff F, Meissner L, Schropp E, Lichtmannegger J, Schulz S, Eberhagen C, Borchard S, Aichler M, Adamski J, Plesnila N, Rothenfusser S, Kroemer G, Zischka H (2013) A semi-automated method for isolating functionally intact mitochondria from cultured cells and tissue biopsies. Anal Biochem 443:66-74.

Abstracts

 PublishedReference
Cecatto 2023 BPS2023 San Diego2023
Sabine Schmitt
Cecatto C, Schmitt Sabine, Cardoso L, Videja M, Dambrova M, Makrecka-Kuka M, Liepinsh E, Gnaiger E (2023) Contribution of fatty acid oxidation to respiratory control in brain mitochondria. 67th Annual Meeting of the Biophysical Society.
Schmitt 2023 BPS2023 San Diego2023
Erich Gnaiger
Schmitt S, Cardoso LHD, Cecatto C, Komlodi T, Gnaiger Erich (2023) Mitochondrial bioenergetics – a quantitative analytical and diagnostic approach. 67th Annual Meeting of the Biophysical Society.
Donnelly 2022 Abstract Bioblast20222.1. «10+5»
Donnelly Chris
Donnelly Chris, Schmitt S, Cecatto C, Cardoso L, Komlodi T, Place N, Kayser B, Gnaiger E (2022) The ABC of hypoxia – what is the norm. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001
»MitoFit Preprint« »Watch the presentation«
Schmitt 2022 Abstract Bioblast20222.2. «10+5»
Sabine Schmitt
Schmitt Sabine, Gnaiger E (2022) Using oxygen and hydrogen gas in studies of mitochondrial respiration and hydrogen peroxide production under hyperoxic, normoxic, and hypoxic conditions. Bioblast 2022: BEC Inaugural Conference. In: https://doi.org/10.26124/bec:2022-0001 »Watch the presentation«
Schmitt 2022 EBEC2022
Sabine Schmitt
Schmitt S, Gnaiger E (2022) Short-term effect of molecular hydrogen on mitochondrial respiration and hydrogen peroxide production in permeabilized HEK 293T cells. EBEC 2022.


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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping


Schmitt Sabine


MitoPedia topics: EAGLE 

COST: Member COST WG1: WG1


Bioenergetics Communications

Keywords: Contact sites, proton flux, mitochondrial isolation


Participated at

Visiting scientist in the Oroboros O2k-Laboratory

O2k-Network

Schmitt Sabine: Visiting scientist at the Oroboros O2k-Laboratory

  • Feburary 1 to 29 2020
  • June 1 to 30 2018: Determination of mitochondrial respiration, H2O2 production and ADP-to-ATP phosphorylation in liver cancer cells and isolated mitochondria upon inhibition of mitochondrial translation.
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