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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
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Hunter 2019 J Appl Physiol (1985) | 2019 | Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between VO2max, cycle economy & mitochondrial respiration in untrained/trained. J Appl Physiol (1985) 127:1562-68. | LEAK OXPHOS | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Nunes 2019 Oxid Med Cell Longev | 2019 | Nunes MEM, Schimith LE, da Costa-Silva DG, Lopes AR, Leandro LP, Martins IK, de Mello RS, Hartmann DD, de Carvalho NR, Carvalho da Rosa P, Trevisan R, Di Giulio RT, Posser T, Franco JL (2019) Acute exposure to permethrin modulates behavioral functions, redox, and bioenergetics parameters and induces DNA damage and cell death in larval zebrafish. Oxid Med Cell Longev 2019:9149203. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Zebrafish | |
Madlala 2019 Integr Food Nutr Metab | 2019 | Madlala HP, Maarman GJ, Ojuka E (2019) Fructose impairs mitochondrial respiration and substrate utilization in hepatocytes via the enzyme, glutamate oxaloacetate transaminase. Integr Food Nutr Metab doi: 10.15761/IFNM.1000228. | LEAK OXPHOS ET | N CIV ROX | Permeabilized cells | Human | Liver |
Gonzalez-Mariscal 2019 FASEB J | 2019 | González-Mariscal I, Montoro RA, O'Connell JF, Kim Y, Gonzalez-Freire M, Liu QR, Alfaras I, Carlson OD, Lehrmann E, Zhang Y, Becker KG, Hardivillé S, Ghosh P, Egan JM (2019) Muscle cannabinoid 1 receptor regulates Il-6 and myostatin expression, governing physical performance and whole-body metabolism. FASEB J 33:5850-63. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Monteiro 2019 Thesis | 2019 | Monteiro ARB (2019) Effects of resistance training on mitochondrial function and gene expression of UCP-3 in muscles of ovariectomized rats. Dissertation 82. | LEAK OXPHOS ET | N | Permeabilized tissue | Rat | Skeletal muscle |
Sanchez-de-Diego 2019 iScience | 2019 | Sánchez-de-Diego C, Artigas N, Pimenta-Lopes C, Valer JA, Torrejon B, Gama-Pérez P, Villena JA, Garcia-Roves PM, Rosa JL, Ventura F (2019) Glucose restriction promotes osteocyte specification by activating a PGC-1α-dependent transcriptional program. iScience 15:79-94. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Other cell lines |
Noz 2019 J Am Heart Assoc | 2019 | Noz MP, Hartman YAW, Hopman MTE, Willems PHGM, Tack CJ, Joosten LAB, Netea MG, Thijssen DHJ, Riksen NP (2019) Sixteen-week physical activity intervention in subjects with increased cardiometabolic risk shifts innate immune function towards a less proinflammatory state. J Am Heart Assoc 8:e013764. | LEAK ET | ROX | Intact cells | Human | Blood cells |
Hunter 2019 J Appl Physiol | 2019 | Hunter GR, Moellering DR, Windham ST, Mathis SL, Bamman MM, Fisher G (2019) Relationship between V̇o2peak, cycle economy, and mitochondrial respiration in untrained/trained. J Appl Physiol 127:1562-8. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
Lewis 2019 Am J Physiol Regul Integr Comp Physiol | 2019 | Lewis MT, Kasper JD, Bazil JN, Frisbee JC, Wiseman RW (2019) Skeletal muscle energetics are compromised only during high-intensity contractions in the Goto-Kakizaki rat model of type 2 diabetes. Am J Physiol Regul Integr Comp Physiol 317:R356-68. | LEAK OXPHOS | F N | Isolated mitochondria | Rat | Skeletal muscle |
Bertolini 2019 MBio | 2019 | Bertolini MS, Chiurillo MA, Lander N, Vercesi AE, Docampo R (2019) MICU1 and MICU2 play an essential role in mitochondrial Ca2+ uptake, growth, and infectivity of the human pathogen Trypanosoma cruzi. MBio 10:e00348-19. | LEAK OXPHOS ET | Permeabilized cells | Protists | ||
Diao 2019 Brain Res | 2019 | Diao X, Zhou Z, Xiang W, Jiang Y, Tian N, Tang X, Chen S, Wen J, Chen M, Liu K, Li Q, Liao R (2019) Glutathione alleviates acute intracerebral hemorrhage injury via reversing mitochondrial dysfunction. Brain Res 1727:146514. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Nervous system |
Mann 2019 Oncogene | 2019 | Mann J, Githaka JM, Buckland TW, Yang N, Montpetit R, Patel N, Li L, Baksh S, Godbout R, Lemieux H, Goping IS (2019) Non-canonical BAD activity regulates breast cancer cell and tumor growth via 14-3-3 binding and mitochondrial metabolism. Oncogene 38:3325-39. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX F | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Carteri 2019 Toxicol Lett | 2019 | Carteri RB, Kopzynski A, Menegassi LN, Rodolphi MS, Strogulski NR, Portela LV (2019) Anabolic-androgen steroids effects on bioenergetics responsiveness of synaptic and extrasynaptic mitochondria. Toxicol Lett 307:72-80. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Nervous system |
Reyes-Fermin 2019 Antioxidants (Basel) | 2019 | Reyes-Fermín LM, Avila-Rojas SH, Aparicio-Trejo OE, Tapia E, Rivero I, Pedraza-Chaverri J (2019) The protective effect of alpha-mangostin against cisplatin-induced cell death in LLC-PK1 cells is associated to mitochondrial function preservation. Antioxidants (Basel) 8:E133. | LEAK ROUTINE ET | CIV ROX | Intact cells | Pig | Kidney |
Ruegsegger 2019 FASEB J | 2019 | Ruegsegger GN, Manjunatha S, Summer P, Gopala S, Zabeilski P, Dasari S, Vanderboom PM, Lanza IR, Klaus KA, Nair KS (2019) Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes. FASEB J 33:4458-72. | LEAK OXPHOS | N NS ROX | Isolated mitochondria | Mouse | Nervous system |
Garcia-Roche 2019 PLoS One | 2019 | García-Roche M, Casal A, Mattiauda DA, Ceriani M, Jasinsky A, Mastrogiovanni M, Trostchansky A, Carriquiry M, Cassina A, Quijano C (2019) Impaired hepatic mitochondrial function during early lactation in dairy cows: Association with protein lysine acetylation. PLoS One 14:e0213780. | LEAK OXPHOS ET | N S NS ROX | Intact cells | Bovines | Liver |
Desquiret-Dumas 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | Desquiret-Dumas V, Leman G, Wetterwald C, Chupin S, Lebert A, Khiati S, Le Mao M, Geffroy G, Kane MS, Chevrollier A, Goudenege D, Gadras C, Tessier L, Barth M, Leruez S, Amati-Bonneau P, Henrion D, Bonneau D, Procaccio V, Reynier P, Lenaers G, Gueguen N (2019) Warburg-like effect is a hallmark of complex I assembly defects. Biochim Biophys Acta Mol Basis Dis 1865:2475-89. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Chao 2019 Am J Physiol Cell Physiol | 2019 | Chao T, Gomez BI, Heard TC, Smith BW, Dubick MA, Burmeister DM (2019) Burn-induced reductions in mitochondrial abundance and efficiency are more pronounced with small volumes of colloids in swine. Am J Physiol Cell Physiol 317:C1229-38. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Pig | Heart |
Glombik 2019 Neurotox Res | 2019 | Głombik K, Detka J, Góralska J, Kurek A, Solnica B, Budziszewska B (2019) Brain metabolic alterations in rats showing depression-like and obesity phenotypes. Neurotox Res 37:406-24. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Nervous system |
Fisher-Wellman 2019 Cell Rep | 2019 | Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM (2019) Respiratory phenomics across multiple models of protein hyperacylation in cardiac mitochondria reveals a marginal impact on bioenergetics. Cell Rep 26:1557-72. | LEAK OXPHOS ET | F N S Gp | Isolated mitochondria | Mouse | Heart Skeletal muscle |
Blais-Lecours 2019 Am J Respir Cell Mol Biol | 2019 | Blais-Lecours P, Laouafa S, Arias-Reyes C, Santos WL, Joseph V, Burgess JK, Halayko AJ, Soliz J, Marsolais D (2019) Metabolic adaptation of airway smooth muscle cells to a SPHK2 substrate precedes cytostasis. Am J Respir Cell Mol Biol 62:35-42. | LEAK ROUTINE OXPHOS ET | ROX | Intact cells | Human | Other cell lines |
Trevino 2019 Am J Physiol Endocrinol Metab | 2019 | Trevino MB, Zhang X, Standley RA, Wang M, Han X, Reis FCG, Periasamy M1, Yu G, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2019) Loss of mitochondrial energetics is associated with poor recovery of muscle function but not mass following disuse atrophy. Am J Physiol Endocrinol Metab 317:E899-910. | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Langley 2019 Biochim Biophys Acta Mol Basis Dis | 2019 | Langley MR, Yoon H, Kim HN, Choi CI, Simon W, Kleppe L, Lanza IR, LeBrasseur NK, Matveyenko A, Scarisbrick IA (2019) High fat diet consumption results in mitochondrial dysfunction, oxidative stress, and oligodendrocyte loss in the central nervous system. Biochim Biophys Acta Mol Basis Dis 1866:165630. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Nervous system |
Rutai 2019 Shock | 2019 | Rutai A, Fejes R, Juhász L, Tallósy SP, Poles MZ, Földesi I, Mészáros AT, Szabó A, Boros M, Kaszaki J (2019) Endothelin A and B receptors: Potential pargets for microcirculatory-mitochondrial therapy in experimental sepsis. Shock 54:87-95. | LEAK OXPHOS | N S ROX | Homogenate | Rat | Liver |
Scheiber 2019 Exp Mol Med | 2019 | Scheiber D, Jelenik T, Zweck E, Horn P, Schultheiss HP, Lassner D, Boeken U, Saeed D, Kelm M, Roden M, Westenfeld R, Szendroedi J (2019) High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure. Exp Mol Med 51:16. | LEAK OXPHOS ET | F N NS | Permeabilized tissue Isolated mitochondria | Human | Heart |
Pedrotti 2019 Sci Adv | 2019 | Pedrotti S, Caccia R, Neguembor MV, Garcia-Manteiga JM, Ferri G, de Palma C, Canu T, Giovarelli M, Marra P, Fiocchi A, Molineris I, Raso M, Sanvito F, Doglioni C, Esposito A, Clementi E, Gabellini D (2019) The Suv420h histone methyltransferases regulate PPAR-γ and energy expenditure in response to environmental stimuli. Sci Adv 5:eaav1472. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Intact cells | Mouse | Fat |
Majiene 2019 Nutrients | 2019 | Majiene D, Kuseliauskyte J, Stimbirys A, Jekabsone A (2019) Comparison of the effect of native 1,4-naphthoquinones plumbagin, menadione, and lawsone on viability, redox status, and mitochondrial functions of C6 glioblastoma cells. Nutrients 11:E1294. | LEAK OXPHOS ET | N NS | Permeabilized cells | Rat | Nervous system |
Aguilar 2019 Cell Rep | 2019 | Aguilar E, Esteves P, Sancerni T, Lenoir V, Aparicio T, Bouillaud F, Dentin R, Prip-Buus C, Ricquier D, Pecqueur C, Guilmeau S, Alves-Guerra MC (2019) UCP2 deficiency increases colon tumorigenesis by promoting lipid synthesis and depleting NADPH for antioxidant defenses. Cell Rep 28:2306-16. | LEAK OXPHOS | N | Homogenate | Mouse | Endothelial;epithelial;mesothelial cell |
Rajendran 2019 EMBO Mol Med | 2019 | Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456. | LEAK OXPHOS ET | N S CIV NS | Isolated mitochondria | Mouse | Liver Kidney Heart |
Trefts 2019 Am J Physiol Endocrinol Metab | 2019 | Trefts E, Hughey CC, Lantier L, Lark DS, Boyd KL, Pozzi A, Zent R, Wasserman DH (2019) Energy metabolism couples hepatocyte integrin-linked kinase to liver glucoregulation and the postabsorptive response of mice in an age-dependent manner. Am J Physiol Endocrinol Metab 316:1118-35. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
Jaiswal 2019 Mol Metab | 2019 | Jaiswal N, Gavin MG, Quinn WJ 3rd, Luongo TS, Gelfer RG, Baur JA, Titchenell PM (2019) The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis. Mol Metab 28:1-13. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Skeletal muscle |
Gopalakrishna 2019 Nucleic Acids Res | 2019 | Gopalakrishna S, Pearce SF, Dinan AM, Schober FA, Cipullo M, Spåhr H, Khawaja A, Maffezzini C, Freyer C, Wredenberg A, Atanassov I, Firth AE, Rorbach J (2019) C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis. Nucleic Acids Res 47:9386-99. | LEAK ET | Permeabilized cells | Human | HEK | |
Anderson 2019 Acta Neuropathol | 2019 | Anderson CJ, Bredvik K, Burstein SR, Davis C, Meadows SM, Dash J, Case L, Milner TA, Kawamata H, Zuberi A, Piersigilli A, Lutz C, Manfredi G (2019) ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. Acta Neuropathol 138:103-21. | LEAK | N S | Isolated mitochondria | Mouse | Heart |
Chroeis 2019 Eur J Sport Sci | 2019 | Chrøis KM, Dohlmann TL, Søgaard D, Hansen CV, Dela F, Helge JW, Larsen S (2019) Mitochondrial adaptations to high intensity interval training in older females and males. Eur J Sport Sci 20:135-45. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Human | Skeletal muscle |
Boardman 2019 Can J Physiol Pharmacol | 2019 | Boardman NT, Falck AT, Lund T, Chu X, Martin-Armas M, Norvik JV, Jenssen TG, Ytrehus K (2019) Human concentrations of uric acid scavenges adaptive and maladaptive ROS in isolated rat hearts subjected to ischemic stress. Can J Physiol Pharmacol 98:139-46. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Heart |
Wang 2019 Metabolism | 2019 | Wang D, Liu CD, Li HF, Tian ML, Pan JQ, Shu G, Jiang QY, Yin YL, Zhang L (2019) LSD1 mediates microbial metabolite butyrate-induced thermogenesis in brown and white adipose tissue. Metabolism 102:154011. | LEAK | F N | Isolated mitochondria | Mouse | Fat |
Schweitzer 2019 FASEB J | 2019 | Schweitzer GG, Collier SL, Chen Z, McCommis KS, Pittman SK, Yoshino J, Matkovich SJ, Hsu FF, Chrast R, Eaton JM, Harris TE, Weihl CC, Finck BN (2019) Loss of lipin 1-mediated phosphatidic acid phosphohydrolase activity in muscle leads to skeletal myopathy in mice. FASEB J 33:652-67. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Inigo 2019 Mol Metab | 2019 | Inigo MR, Amorese AJ, Tarpey MD, Balestrieri NP, Jones KG, Patteson DJ, Jackson KC, Torres MJ, Lin CT, Smith CD, Heden TD, McMillin SL, Weyrauch LA, Stanley EC, Schmidt CA, Kilburg-Basnyat BB, Reece SW, Psaltis CE, Leinwand LA, Funai K, McClung JM, Gowdy KM, Witczak CA, Lowe DA, Neufer PD, Spangenburg EE (2019) Estrogen receptor-α in female skeletal muscle is not required for regulation of muscle insulin sensitivity and mitochondrial regulation. Mol Metab 34:1-15. | LEAK OXPHOS | F N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Courtes 2019 Biomed Pharmacother | 2019 | Courtes AA, de Carvalho NR, Gonçalves DF, Hartmann DD, da Rosa PC, Dobrachinski F, Franco JL, de Souza DOG, Soares FAA (2019) Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats. Biomed Pharmacother 111:1438-46. | OXPHOS LEAK | N S NS ROX | Isolated mitochondria | Rat | Liver |
Chao 2019 J Appl Physiol (1985) | 2019 | Chao T, Burmeister DM, Corona BT, Greising SM (2019) Oxidative pathophysiology following volumetric muscle loss injury in a porcine model. J Appl Physiol (1985) 126:1541-49. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Pig | Skeletal muscle |
Holsgrove 2019 Thesis | 2019 | Holsgrove A (2019) The effect of temperature on cardiac energetics in the rainbow trout, Onchorhynchus mykiss. Phd Thesis 166. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Fishes | Heart |
Doerrier 2019 MitoFit Preprint Arch EA | 2019 | Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2019) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. https://doi.org/10.26124/mitofit:ea19.MiPSchool.0009 | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
McMurray 2019 FASEB J | 2019 | McMurray F, MacFarlane M, Kim K, Patten DA, Wei-LaPierre L, Fullerton MD, Harper ME (2019) Maternal diet-induced obesity alters muscle mitochondrial function in offspring without changing insulin sensitivity. FASEB J 33:13515-26. | LEAK OXPHOS | F N S CIV ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Spinazzi 2019 Proc Natl Acad Sci U S A | 2019 | Spinazzi M, Radaelli E, Horré K, Arranz AM, Gounko NV, Agostinis P, Maia TM, Impens F, Morais VA, Lopez-Lluch G, Serneels L, Navas P, De Strooper B (2019) PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. Proc Natl Acad Sci U S A 116:277-86. | LEAK OXPHOS ET | N S CIV NS ROX | Intact cells Permeabilized cells Isolated mitochondria | Mouse | Nervous system |
Itkis 2019 Mitochondrion | 2019 | Itkis Y, Krylova T, Pechatnikova NL, De Grassi A, Tabakov VY, Pierri CL, Aleshin V, Boyko A, Bunik VI, Zakharova EY (2019) A novel variant m.641A>T in the mitochondrial MT-TF gene is associated with epileptic encephalopathy in adolescent. Mitochondrion 47:10-17. | LEAK ROUTINE OXPHOS ET | N CIV NS ROX | Intact cells Permeabilized cells | Human | Fibroblast |
Berru 2019 Sci Rep | 2019 | Berru FN, Gray SE, Thome T, Kumar RA, Salyers ZR, Coleman M, Dennis Le, O'Malley K, Ferreira LF, Berceli SA, Scali ST, Ryan TE (2019) Chronic kidney disease exacerbates ischemic limb myopathy in mice via altered mitochondrial energetics. Sci Rep 9:15547. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Flis 2019 Int J Mol Sci | 2019 | Flis DJ, Dzik K, Kaczor JJ, Cieminski K, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2019) Swim training modulates mouse skeletal muscle energy metabolism and ameliorates reduction in grip strength in a mouse model of amyotrophic lateral sclerosis. Int J Mol Sci 20:E233. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Skeletal muscle |
Rocco-Machado 2019 Free Radic Biol Med | 2019 | Rocco-Machado N, Cosentino-Gomes D, Nascimento MT, Paes-Vieira L, Khan YA, Mittra B, Andrews NW, Meyer-Fernandes JR (2019) Leishmania amazonensis ferric iron reductase (LFR1) is a bifunctional enzyme: Unveiling a NADPH oxidase activity. https://doi.org/10.1016/j.freeradbiomed.2019.08.026 | LEAK ROUTINE ET | ROX | Intact organism Intact cells | Protists | |
Jaskiewicz 2019 J Clin Med | 2019 | Jaśkiewicz A, Pająk B, Łabieniec-Watała M, De Palma C, Orzechowski A (2019) Diverse action of selected statins on skeletal muscle cells - An attempt to explain the protective effect of geranylgeraniol (GGOH) in statin-associated myopathy (SAM). J Clin Med 8:694. | ROUTINE OXPHOS ET LEAK | N S NS ROX | Permeabilized cells Intact cells | Mouse | Skeletal muscle Other cell lines |
Benoist 2019 Sci Rep | 2019 | Benoist L, Chadet S, Genet T, Lefort C, Heraud A, Danila MD, Muntean DM, Baron C, Angoulvant D, Babuty D, Bourguignon T, Ivanes F (2019) Stimulation of P2Y11 receptor protects human cardiomyocytes against hypoxia/reoxygenation injury and involves PKCε signaling pathway. Sci Rep 9:11613. | LEAK ROUTINE ET | ROX | Intact cells | Human | Heart |
Kumari 2019 Am J Physiol Heart Circ Physiol | 2019 | Kumari S, Braun RK, Tetri L, Barton GP, Hacker TA, Goss KN (2019) Bimodal right ventricular dysfunction after postnatal hyperoxia exposure: implications for the preterm heart. Am J Physiol Heart Circ Physiol 317:H1272-81. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Heart |
Skrivergaard 2019 Viruses | 2019 | Skrivergaard S, Jensen MS, Rolander TB, Nguyen TBN, Bundgaard A, Nejsum LN, Martensen PM (2019) The cellular localization of the p42 and p46 oligoadenylate synthetase 1 isoforms and their impact on mitochondrial respiration. Viruses 11:E1122. | LEAK ROUTINE OXPHOS ET | N S ROX | Permeabilized cells Intact cells | Human | Other cell lines HeLa |
Rawat 2019 J Mol Biol | 2019 | Rawat S, Anusha V, Jha M, Sreedurgalakshmi K, Raychaudhuri S (2019) Aggregation of respiratory complex subunits marks the onset of proteotoxicity in proteasome inhibited cells. J Mol Biol 431:996-1015. | OXPHOS LEAK | N S CIV ROX | Permeabilized cells | Mouse | Nervous system Other cell lines |
Esteves 2019 Oncogene | 2019 | Esteves P, Dard L, Brillac A, Hubert C, Sarlak S, Rousseau B, Dumon E, Izotte J, Bonneu M, Lacombe D, Dupuy JW, Amoedo N, Rossignol R (2019) Nuclear control of lung cancer cells migration, invasion and bioenergetics by eukaryotic translation initiation factor 3F. Oncogene 39:617-36. | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Ahmed 2019 Mol Nutr Food Res | 2019 | Ahmed N, Tcheng M, Roma A, Buraczynski M, Jayanth P, Rea K, Akhtar TA, Spagnuolo PA (2019) Avocatin B protects against lipotoxicity and improves insulin sensitivity in diet-induced obesity. Mol Nutr Food Res 63:e1900688. | LEAK ROUTINE ET | N ROX | Intact cells | Mouse Rat | Skeletal muscle Islet cell;pancreas;thymus |
Johansen 2019 Comp Biochem Physiol C Toxicol Pharmacol | 2019 | Johansen JL, Esbaugh AJ (2019) Oil-induced responses of cardiac and red muscle mitochondria in red drum (Sciaenops ocellatus). Comp Biochem Physiol C Toxicol Pharmacol 219:35-41. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Fishes | Heart Skeletal muscle |
Kappler 2019 Am J Physiol Endocrinol Metab | 2019 | Kappler L, Hoene M, Hu C, von Toerne C, Li J, Bleher D, Hoffmann C, Böhm A, Kollipara L, Zischka H, Königsrainer A, Häring HU, Peter A, Xu G, Sickmann A, Hauck SM, Weigert C, Lehmann R (2019) Linking bioenergetic function of mitochondria to tissue-specific molecular fingerprints. Am J Physiol Endocrinol Metab 317:E374-E387. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue Isolated mitochondria | Human Mouse | Skeletal muscle Liver |
Perry 2019 J Mol Cell Cardiol | 2019 | Perry JB, Davis GN, Allen ME, Makrecka-Kuka M, Dambrova M, Grange RW, Shaikh SR, Brown DA (2019) Cardioprotective effects of idebenone do not involve ROS scavenging: Evidence for mitochondrial complex I bypass in ischemia/reperfusion injury. J Mol Cell Cardiol 135:160-171. | LEAK OXPHOS | N S ROX | Isolated mitochondria Permeabilized cells | Rat | Heart |
Qaed 2019 Oxid Med Cell Longev | 2019 | Qaed E, Wang J, Almoiliqy M, Song Y, Liu W, Chu P, Alademi S, Alademi M, Li H, Alshwmi M, Al-Azab M, Ahsan A, Mahdi S, Han G, Niu M, Ali A, Shopit A, Wang H, Li X, Qaid A, Ma X, Li T, Peng J, Ma J, Zhang J, Tang Z (2019) Phosphocreatine improves cardiac dysfunction by normalizing mitochondrial respiratory function through JAK2/STAT3 signaling pathway in vivo and in vitro. Oxid Med Cell Longev 2019:6521218. | LEAK OXPHOS ET ROUTINE | N S NS ROX | Homogenate Isolated mitochondria Permeabilized cells Intact cells | Rat | Heart |
Alvarez 2019 Chem Biol Interact | 2019 | Álvarez Santos MR, Duarte YB, Güiza FM, Romero Bohórquez AR, Mendez-Sanchez SC (2019) Effects of new tetrahydroquinoline-isoxazole hybrides on bioenergetics of hepatocarcinoma Hep-G2 cells and rat liver mitochondria. Chem Biol Interact 302:164-71. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Power 2019 PLoS One | 2019 | Power AS, Norman R, Jones TLM, Hickey AJ, Ward ML (2019) Mitochondrial function remains impaired in the hypertrophied right ventricle of pulmonary hypertensive rats following short duration metoprolol treatment. PLoS One 14:e0214740. | LEAK OXPHOS | N NS | Permeabilized tissue | Rat | Heart |
Cedrone 2019 Thesis | 2019 | Cedrone M (2019) Low birth weight and post-natal diet induced alterations in skeletal muscle oxygen consumption and fiber type composition. Master's Thesis 83. | LEAK OXPHOS | N S | Permeabilized tissue Intact cells | Guinea pig Mouse | Skeletal muscle |
Rose 2019 Am J Physiol Endocrinol Metab | 2019 | Rose S, Carvalho E, Diaz EC, Cotter M, Bennuri SC, Azhar G, Frye RE, Adams SH, Børsheim E (2019) A comparative study of mitochondrial respiration in circulating blood cells and skeletal muscle fibers in women. Am J Physiol Endocrinol Metab 317:E503-E512. https://doi.org/10.1152/ajpendo.00084.2019 | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells Platelet |
Cornacchia 2019 Cell Stem Cell | 2019 | Cornacchia D, Zhang C, Zimmer B, Chung SY, Fan Y, Soliman MA, Tchieu J, Chambers SM, Shah H, Paull D, Konrad C, Vincendeau M, Noggle SA, Manfredi G, Finley LWS, Cross JR, Betel D, Studer L (2019) Lipid deprivation induces a stable, naive-to-primed intermediate state of pluripotency in human PSCs. Cell Stem Cell 25:120-36. | LEAK ET | N CIV | Intact cells | Human | Stem cells |
Bodis 2019 J Clin Endocrinol Metab | 2019 | Bodis K, Jelenik T, Lundbom J, Markgraf DF, Strom A, Zaharia OP, Karusheva Y, Burkart V, Muessig K, Kupriyanova Y, Ouni M, Wolkersdorfer M, Hwang JH, Ziegler D, Schuermann A, Roden M, Szendroedi J (2019) Expansion and impaired mitochondrial efficiency of deep subcutaneous adipose tissue in recent-onset type 2 diabetes. J Clin Endocrinol Metab 105:dgz267. | LEAK OXPHOS ET | F N NS | Permeabilized cells | Human | Fat |
Roux 2019 PLoS Pathog | 2019 | Roux A, Leroy H, De Muylder B, Bracq L, Oussous S, Dusanter-Fourt I, Chougui G, Tacine R, Randriamampita C, Desjardins D, Le Grand R, Bouillaud F, Benichou S, Margottin-Goguet F, Cheynier R, Bismuth G, Mangeney M (2019) FOXO1 transcription factor plays a key role in T cell-HIV-1 interaction. https://doi.org/10.1371/journal.ppat.1007669 | LEAK ROUTINE ET | Intact cells | Human | Lymphocyte | |
Macedo 2019 Biochim Biophys Acta Mol Cell Biol Lipids | 2019 | Macedo F, Martins GL, Luévano-Martínez LA, Viana GM, Riske KA, Inague A, Yoshinaga MY, Aguilaniu H, Miyamoto S, Glezer I, da Cunha FM (2019) Lipase-like 5 enzyme controls mitochondrial activity in response to starvation in Caenorhabditis elegans. Biochim Biophys Acta Mol Cell Biol Lipids 1865:158539. | LEAK OXPHOS | N CIV NS | Isolated mitochondria | Caenorhabditis elegans | |
McBride 2019 Arch Biochem Biophys | 2019 | McBride S, Wei-LaPierre L, McMurray F, MacFarlane M, Qiu X, Patten DA, Dirksen RT, Harper ME (2019) Skeletal muscle mitoflashes, pH, and the role of uncoupling protein-3. Arch Biochem Biophys 663:239-48. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Wiberg 2019 Eur Heart J Acute Cardiovasc Care | 2019 | Wiberg S, Stride N, Bro-Jeppesen J, Holmberg MJ, Kjærgaard J, Larsen S, Donnino MW, Hassager C, Dela F (2019) Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest. Eur Heart J Acute Cardiovasc Care 9:S138-44. | OXPHOS ET LEAK | N NS | Permeabilized tissue | Human | Skeletal muscle |
Lemieux 2019 bioRxiv | 2019 | Lemieux H, Subarsky P, Doblander C, Wurm M, Troppmair J, Gnaiger E (2019) Mitochondrial respiratory function as an early biomarker of apoptosis induced by growth factor removal. bioRxiv doi: https://doi.org/10.1101/151480 . | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Mouse | Blood cells |
MiPNet12.01 Suppl T-issue | 2018-11-18 | MitoPathways at the Q-junction: mouse skeletal muscle fibers. | LEAK ROUTINE ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
MiPNet21.06 SUIT RP | 2018-06-25 | SUIT reference protocol for OXPHOS analysis by high-resolution respirometry. | LEAK OXPHOS ET | F N S Gp CIV NS Other combinations | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria | ||
Quispe 2018 Redox Biol | 2018 | Quispe RL, Jaramillo ML, Galant LS, Engel D, Dafre AL, Teixeira da Rocha JB, Radi R, Farina M, de Bem AF (2018) Diphenyl diselenide protects neuronal cells against oxidative stress and mitochondrial dysfunction: Involvement of the glutathione-dependent antioxidant system. Redox Biol 20:118-29. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines |
Wu 2018 Adv Sci | 2018 | Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Scheiber 2018 J Cardiovasc Transl Res | 2018 | Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Human | Heart |
Chou 2018 Int J Cardiol | 2018 | Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Intact cells Permeabilized cells | Human | Platelet Blood cells |
Trewin 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Trewin AJ, Parker L, Shaw CS, Hiam D, Garnham AP, Levinger I, McConell GK, Stepto NK (2018) Acute HIIE elicits similar changes in human skeletal muscle mitochondrial H2O2 release, respiration and cell signaling as endurance exercise even with less work. Am J Physiol Regul Integr Comp Physiol 315:R1003-R1016. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Valentine 2018 J Gerontol A Biol Sci Med Sci | 2018 | Valentine JM, Li ME, Shoelson SE, Zhang N, Reddick RL, Musi N (2018) NFκB regulates muscle development and mitochondrial function. J Gerontol A Biol Sci Med Sci 75:647-53. | LEAK OXPHOS ET | F N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Dawson 2018 Acta Physiol (Oxf) | 2018 | Dawson NJ, Lyons SA, Henry DA, Scott GR (2018) Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol (Oxf) 223:e13030. | LEAK OXPHOS | N CIV NS | Permeabilized tissue | Other mammals | Skeletal muscle |
Leckey 2018 FASEB J | 2018 | Leckey JJ, Hoffman NJ, Parr EB, Devlin BL, Trewin AJ, Stepto NK, Morton JP, Burke LM, Hawley JA (2018) High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. FASEB J 32:2979-91. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Komlodi 2018 Methods Mol Biol | 2018 | Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Permeabilized tissue | Human Mouse | Skeletal muscle HEK |
Britto 2018 BMC Biol | 2018 | Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65. https://doi.org/10.1186/s12915-018-0525-4 | LEAK OXPHOS | F N NS Other combinations | Permeabilized cells Isolated mitochondria | Mouse | Skeletal muscle |
Hedges 2018 J Appl Physiol (1985) | 2018 | Hedges CP, Woodhead JST, Wang HW, Mitchell CJ, Cameron-Smith D, Hickey AJR, Merry TL (2018) Peripheral blood mononuclear cells do not reflect skeletal muscle mitochondrial function or adaptation to high-intensity interval training in healthy young men. J Appl Physiol (1985) 126:454-61. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue Intact cells | Human | Skeletal muscle Blood cells |
Petiz 2018 Chem Biol Interact | 2018 | Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Liver |
Simard 2018 J Vis Exp | 2018 | Simard CJ, Pelletier G, Boudreau LH, Hebert-Chatelain E, Pichaud N (2018) Measurement of mitochondrial oxygen consumption in permeabilized fibers of Drosophila using minimal amounts of tissue. J Vis Exp 134. | LEAK OXPHOS | N Gp CIV NS ROX | Permeabilized tissue | Drosophila | |
Lica 2018 Stem Cells Dev | 2018 | Lica JJ, Grabe GJ, Heldt M, Misiak M, Bloch P, Serocki M, Switalska M, Wietrzyk J, Baginski M, Hellmann A, Borowski E, Skladanowski A (2018) Cell density-dependent cytological stage profile and its application for a screen of cytostatic agents active towards Leukemic Stem Cells. Stem Cells Dev 27:488-513. | LEAK ROUTINE ET | N | Human Mouse | Heart Blood cells Other cell lines | |
Bytautiene 2018 J Dev Orig Health Dis | 2018 | Bytautiene Prewit E, Porter C, La Rosa M, Bhattarai N, Yin H, Gamble P, Kechichian T, Sidossis LS (2018) Adipose tissue uncoupling protein 1 levels and function are increased in a mouse model of developmental obesity induced by maternal exposure to high-fat diet. J Dev Orig Health Dis 9:401-8. | LEAK | F N | Permeabilized tissue | Mouse | Fat |
Burtscher 2018 Front Mol Neurosci | 2018 | Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Sprenger 2018 EMBO Mol Med | 2018 | Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2018) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11:e9288. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Nervous system |
Farias 2018 Int J Biol Macromol | 2018 | Farias CLA, Martinez GR, Cadena SMSC, Mercê ALR, de Oliveira Petkowicz CL, Noleto GR (2018) Cytotoxicity of xyloglucan from Copaifera langsdorffii and its complex with oxovanadium (IV/V) on B16F10 cells. Int J Biol Macromol 121:1019-28. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
Lasalvia 2018 PLOS ONE | 2018 | Lasalvia M, Scrima R, Perna G, Piccoli C, Capitanio N, Biagi PF, Schiavulli L, Ligonzo T, Centra M, Casamassima G, Ermini A, Capozzi V (2018) Exposure to 1.8 GHz electromagnetic fields affects morphology, DNA-related Raman spectra and mitochondrial functions in human lympho-monocytes. PLOS ONE 13:e0192894. | LEAK ET | Intact cells | Human | Lymphocyte | |
Hughey 2018 J Biol Chem | 2018 | Hughey CC, Trefts E, Bracy DP, James FD, Donahue EP, Wasserman DH (2018) Glycine N-methyltransferase deletion in mice diverts carbon flux from gluconeogenesis to pathways that utilize excess methionine cycle intermediates. J Biol Chem 293:11944-54. | LEAK ROUTINE ET | Intact cells | Mouse | Liver | |
Jang 2018 J Med Toxicol | 2018 | Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Blood cells |
Burstein 2018 Hum Mol Genet | 2018 | Burstein SR, Valsecchi F, Kawamata H, Bourens M, Zeng R, Zuberi A, Milner TA, Cloonan SM, Lutz C, Barrientos A, Manfredi G (2018) In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions. Hum Mol Genet 27:160-77. | LEAK OXPHOS ET | N CIV | Isolated mitochondria Intact cells | Human Mouse | Heart Skeletal muscle Nervous system HEK |
Zhang 2018 J Gerontol A Biol Sci Med Sci | 2018 | Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22. | LEAK OXPHOS | F N NS | Mouse | Skeletal muscle | |
Salin 2018 Integr Comp Biol | 2018 | Salin K, Villasevil EM, Anderson GJ, Selman C, Chinopoulos C, Metcalfe NB (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integr Comp Biol 58:486-94. | LEAK OXPHOS | N S NS ROX | Homogenate | Fishes | Liver |
Giacco 2018 FASEB J | 2018 | Giacco A, Delli Paoli G, Senese R, Cioffi F, Silvestri E, Moreno M, Ruoppolo M, Caterino M, Costanzo M, Lombardi A, Goglia F, Lanni A, de Lange P (2018) The saturation degree of fatty acids and their derived acylcarnitines determines the direct effect of metabolically active thyroid hormones on insulin sensitivity in skeletal muscle cells. FASEB J 33:1811-23. | LEAK ET ROUTINE | ROX | Intact cells | Rat | Skeletal muscle |
Havird 2018 bioRxiv | 2018 | Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2018) Assessing mitochondrial function in angiosperms with highly divergent mitochondrial genomes. bioRxiv doi: https://doi.org/10.1101/448902. | LEAK OXPHOS | N S CIV NS | Isolated mitochondria | Plants | |
Woodman 2018 FASEB J | 2018 | Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Rat | Liver Kidney |
Cree-Green 2018 Diabetes | 2018 | Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, Mcclatchey PM, Bauer TA, Regensteiner JG, Reusch JEB (2018) Supplemental oxygen improves in-vivo mitochondrial oxidative phosphorylation flux in sedentary obese adults with type 2 diabetes. Diabetes 67:1369-79. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Rundle 2018 Environ Sci Technol | 2018 | Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Fishes | Liver |
Ejarque 2018 Int J Obes (Lond) | 2018 | Ejarque M, Ceperuelo-Mallafré V, Serena C, Maymo-Masip E, Duran X, Díaz-Ramos A, Millan-Scheiding M, Núñez-Álvarez Y, Núñez-Roa C, Gama P, Garcia-Roves PM, Peinado MA, Gimble JM, Zorzano A, Vendrell J, Fernández-Veledo S (2018) Adipose tissue mitochondrial dysfunction in human obesity is linked to a specific DNA methylation signature in adipose-derived stem cells. Int J Obes (Lond) 43:1256-68. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | Fat |
Kauppila 2018 Thesis | 2018 | Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart Liver |
Siira 2018 EMBO Rep | 2018 | Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart |
Coleman 2018 Sci Rep | 2018 | Coleman V, Sa-Nguanmoo P, Koenig J, Schulz TJ, Grune T, Klaus S, Kipp AP, Ost M (2018) Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep 8:2446. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Tillmans 2018 Thesis | 2018 | Tillmans F (2018) Effect of normobaric hypoxia on leukemic vell lines in vitro. Dissertation p92. | LEAK ROUTINE ET | N S NS ROX | Intact cells Permeabilized cells | Human | Other cell lines Lymphocyte |
Rossignoli 2018 J Nutr Biochem | 2018 | Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23. | LEAK ET OXPHOS | N S | Permeabilized cells Isolated mitochondria | Mouse | Skeletal muscle Nervous system Liver Fat |
Arnoux 2018 Elife | 2018 | Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. Elife 7:e38744. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Dela 2018 Acta Physiol (Oxf) | 2018 | Dela F, Ingersen A, Andersen NB, Nielsen MB, Petersen HHH, Hansen CN, Larsen S, Wojtaszewski J, Helge JW (2018) Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes. Acta Physiol (Oxf) 226:e13245. | OXPHOS LEAK | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Kener 2018 J Vis Exp | 2018 | Kener KB, Munk DJ, Hancock CR, Tessem JS (2018) High-resolution respirometry to measure mitochondrial function of intact beta cells in the presence of natural compounds. J Vis Exp 131. | LEAK ET | ROX | Intact cells | Islet cell;pancreas;thymus | |
Sumbalova 2018 Nova Sciences | 2018 | Sumbalová Z, Garcia-Souza LF, Cizmarova B, Volani C, Gnaiger E (2018) Analysis of mitochondrial function in human blood cells. In: Recent advances in mitochondrial medicine and coenzyme Q10. Gvozdjáková A, Cornelissen G, Singh RB eds, Nova Sciences:255-68. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Blood cells |
Kahl 2018 Stroke | 2018 | Kahl A, Stepanova A, Konrad C, Anderson C, Manfredi G, Zhou P, Iadecola C, Galkin A (2018) Critical role of flavin and glutathione in complex I-mediated bioenergetic failure in brain ischemia/reperfusion injury. Stroke 49:1223-31. | LEAK OXPHOS | CIV | Homogenate | Mouse | Nervous system |
Holland 2018 Cell Death Dis | 2018 | Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Genital |
Silaidos 2018 Biol Sex Differ | 2018 | Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Nervous system Blood cells |
Zdralevic 2018 J Biol Chem | 2018 | Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M (2018) Double genetic disruption of lactate dehydrogenase A and B is required to ablate the 'Warburg effect' restricting tumor growth to oxidative metabolism. J Biol Chem 293:15947-61. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Weisz 2018 Hum Mol Genet | 2018 | Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106. | OXPHOS ET LEAK | N S NS ROX | Isolated mitochondria | Drosophila | Skeletal muscle |
Reguis Yadao 2018 Thesis | 2018 | Reguis Yadao DR (2018) Smooth muscle cell mitochondrial respiration – effects of aerobic training and type I diabetes. Master's Thesis 71. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Other cell lines |
Manoharan 2018 Thesis | 2018 | Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Fishes | Heart Liver |
Ahn 2018 Redox Biol | 2018 | Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H (2018) Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol 17:47-58. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Lu 2018 Cell Rep | 2018 | Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Hernandez-Resendiz 2018 J Cell Physiol | 2018 | Hernández-Reséndiz I, Gallardo-Pérez JC, López-Macay A, Robledo-Cadena DX, García-Villa E, Gariglio P, Saavedra E, Moreno-Sánchez R, Rodríguez-Enríquez S (2018) Mutant p53R248Q downregulates oxidative phosphorylation and upregulates glycolysis under normoxia and hypoxia in human cervix cancer cells. J Cell Physiol 234:5524-36. | LEAK | Intact cells | Human | HeLa | |
Walczak 2018 FASEB J | 2018 | Walczak J, Dębska-Vielhaber G, Vielhaber S, Szymański J, Charzyńska A, Duszyński J, Szczepanowska J (2018) Distinction of sporadic and familial forms of ALS based on mitochondrial characteristics. FASEB J 33:4388-403. | OXPHOS LEAK ROUTINE | N S | Permeabilized cells | Human | Fibroblast |
Fernandes-Siqueira 2018 mSphere | 2018 | Fernandes-Siqueira LO, Zeidler JD, Sousa BG, Ferreira T, Da Poian AT (2018) Anaplerotic role of glucose in the oxidation of endogenous fatty acids during Dengue virus infection. mSphere 3.pii: e00458-17. | LEAK ET | F ROX | Intact cells | Human | Liver Other cell lines |
Kong 2018 Proteomics | 2018 | Kong D, Tian X, Li Y*, Zhang S, Cheng Y, Huo L, Ma H, Yang Z, Ren L, Zhang M, Zhang W (2018) Revealing the inhibitory effect of ginseng on mitochondrial respiration through synaptosomal proteomics. Proteomics 18:e1700354. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Deschaseaux 2018 US Patent | 2018 | Deschaseaux F, Guilloton F, Muller S, Sensebe L, Casteilla L, Carriere-Pazat A (2018) Method for obtaining human brown/beige adipocytes . US Patent US20180216070A1. | LEAK ROUTINE ET | ROX | Intact cells | Human | Fat |
Lee 2018 Neurol Genet | 2018 | Lee RG, Sedghi M, Salari M, Shearwood AJ, Stentenbach M, Kariminejad A, Goullee H, Rackham O, Laing NG, Tajsharghi H, Filipovska A (2018) Early-onset Parkinson disease caused by a mutation in CHCHD2 and mitochondrial dysfunction. Neurol Genet 4:e276. | LEAK OXPHOS ET | N S CIV NS | Permeabilized cells | Human | Fibroblast |
Mahapatra 2018 Clin Sci (Lond) | 2018 | Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690 | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Human | Nervous system Blood cells |
Eimre 2018 Oxid Med Cell Longev | 2018 | Eimre M, Paju K, Peet N, Kadaja L, Tarrend M, Kasvandik S, Seppet J, Ivask M, Orlova E, Kõks S (2018) Increased mitochondrial protein levels and bioenergetics in the musculus rectus femoris of Wfs1-deficient mice. Oxid Med Cell Longev 2018:3175313. | OXPHOS LEAK | N S CIV ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Thrush 2018 Int J Obes (Lond) | 2018 | Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Kauppila 2018 Nucleic Acids Res | 2018 | Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse | |
Schiffer 2018 Am J Physiol Renal Physiol | 2018 | Schiffer TA, Gustafsson H, Palm F (2018) Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment. Am J Physiol Renal Physiol 315:F677-F681. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Kidney |
Ryan 2018 JCI Insight | 2018 | Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235. | OXPHOS LEAK | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse Rat | Skeletal muscle |
De Sales 2018 Molecules | 2018 | de Sales NFF, Silva da Costa L, Carneiro TIA, Minuzzo DA, Oliveira FL, Cabral LMC, Torres AG, El-Bacha T (2018) Anthocyanin-rich grape pomace extract (Vitis vinifera L.) from wine industry affects mitochondrial bioenergetics and glucose metabolism in human hepatocarcinoma HepG2 cells. Molecules 23. | LEAK ROUTINE ET | N | Intact cells | Human | Liver Other cell lines |
Kleszczynski 2018 Int J Mol Sci | 2018 | Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786. | LEAK OXPHOS | N NS | Isolated mitochondria | Mouse | Liver |
Christen 2018 Free Radic Biol Med | 2018 | Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Fishes | Heart |
Chabi 2018 J Bioenerg Biomembr | 2018 | Chabi B, Fouret G, Lecomte J, Cortade F, Pessemesse L, Baati N, Coudray C, Lin L, Tong Q, Wrutniak-Cabello C, Casas F, Feillet-Coudray C (2018) Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition. J Bioenerg Biomembr 50:131-42. | LEAK OXPHOS | N S CIV NS | Homogenate Isolated mitochondria | Mouse | Skeletal muscle |
Li 2018 Gene | 2018 | Li Y, Wen S, Li D, Xie J, Wei X, Li X, Liu Y, Fang H, Yang Y, Lyu J (2018) SURF1 mutations in Chinese patients with Leigh syndrome: Novel mutations, mutation spectrum, and the functional consequences. Gene 674:15-24. | LEAK ROUTINE | Intact cells | Human | Blood cells | |
Nielsen 2018 Neurosci Lett | 2018 | Nielsen B, Cejvanovic V, Wörtwein G, Hansen AR, Marstal KK, Weimann A, Bjerring PN, Dela F, Poulsen HE, Jørgensen MB (2018) Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue. Neurosci Lett 690:1-5. | LEAK OXPHOS ET | N NS ROX S | Homogenate | Rat | Nervous system |
Souza 2018 Sci Rep | 2018 | Souza RWA, Alves CRR, Medeiros A, Rolim N, Silva GJJ, Moreira JBN, Alves MN, Wohlwend M, Gebriel M, Hagen L, Sharma A, Koch LG, Britton SL, Slupphaug G, Wisløff U, Brum PC (2018) Differential regulation of cysteine oxidative post-translational modifications in high and low aerobic capacity. Sci Rep 8:17772. | LEAK OXPHOS ET | N S NS | Permeabilized tissue | Rat | Heart Skeletal muscle |
Astrakhanova 2018 Sovrem Tekhnologii Med | 2018 | Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94. | OXPHOS LEAK | N S | Isolated mitochondria | Mouse | Nervous system |
Ost 2018 Curr Opin Clin Nutr Metab Care | 2018 | Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells | Blood cells Platelet Skeletal muscle Liver Fat | |
Davila 2018 Elife | 2018 | Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:e33246. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Skeletal muscle Liver |
Ederer 2018 Int J Mol Sci | 2018 | Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M (2018) Age- and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in Drosophila melanogaster. Int J Mol Sci 19:3351. | LEAK OXPHOS | N | Isolated mitochondria | Drosophila | |
Torres 2018 Cell Metab | 2018 | Torres MJ, Kew KA, Ryan TE, Pennington ER, Lin CT, Buddo KA, Fix AM, Smith CA, Gilliam LA, Karvinen S, Lowe DA, Spangenburg EE, Zeczycki TN, Shaikh SR, Neufer PD (2018) 17β-estradiol directly lowers mitochondrial membrane microviscosity and improves bioenergetic function in skeletal muscle. Cell Metab 27:167-79. https://doi.org/10.1016/j.cmet.2017.10.003 | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Gonzalez-Freire 2018 Aging Cell | 2018 | Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L (2018) Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: the Baltimore longitudinal study of aging. Aging Cell 17. | LEAK OXPHOS | NS | Permeabilized tissue | Human | Skeletal muscle |
Stepanova 2018 J Neurochem | 2018 | Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45. | LEAK OXPHOS | N S Gp NS ROX | Isolated mitochondria | Mouse | Nervous system |
Quispe 2018 Mol Neurobiol | 2018 | Quispe RL, Canto RFS, Jaramillo ML, Barbosa FAR, Braga AL, de Bem AF, Farina M (2018) Design, synthesis, and in vitro evaluation of a novel probucol derivative: protective activity in neuronal cells through GPx upregulation. Mol Neurobiol 55:7619-34. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Nervous system Other cell lines |
Carter 2018 J Physiol | 2018 | Carter HN, Kim Y, Erlich AT, Zarrin-Khat D, Hood DA (2018) Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity. J Physiol 596:3567-84. | LEAK OXPHOS | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Song 2018 J Cell Physiol | 2018 | Song Y, Gao L, Tang Z, Li H, Sun B, Chu P, Qaed E, Ma X, Peng J, Wang S, Hu M, Tang Z (2018) Anticancer effect of SZC015 on pancreatic cancer via mitochondria-dependent apoptosis and the constitutive suppression of activated nuclear factor κB and STAT3 in vitro and in vivo. J Cell Physiol 234:777-88. | LEAK ET | ROX | Intact cells | Human | Islet cell;pancreas;thymus |
Laouafa 2018 Adv Exp Med Biol | 2018 | Laouafa S, Roussel D, Marcouiller F, Soliz J, Bairam A, Joseph V (2018) Role of estradiol receptor beta (ERβ) on arterial pressure, respiratory chemoreflex and mitochondrial function in young and aged female mice. Adv Exp Med Biol 1071:115-27. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Tetri 2018 Front Physiol | 2018 | Tetri LH, Diffee GM, Barton GP, Braun RK, Yoder HE, Haraldsdottir K, Eldridge MW, Goss KN (2018) Sex-specific skeletal muscle fatigability and decreased mitochondrial oxidative capacity in adult rats exposed to postnatal hyperoxia. Front Physiol 9:326. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Skeletal muscle |
Durand 2018 Blood Purif | 2018 | Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Platelet Blood cells |
Banerjee 2018 Cell Transplant | 2018 | Banerjee A*, Lindenmair A, Hennerbichler S, Steindorf P, Steinborn R, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Cellular and site-specific mitochondrial characterization of vital human amniotic membrane. Cell Transplant 27:3-11. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Genital | |
Cruz 2018 Chem Biol Interact | 2018 | Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Drosophila | |
Tyagi 2018 Sci Rep | 2018 | Tyagi A, Nguyen CU, Chong T, Michel CR, Fritz KS, Reisdorph N, Knaub L, Reusch JEB, Pugazhenthi S (2018) SIRT3 deficiency-induced mitochondrial dysfunction and inflammasome formation in the brain. Sci Rep 8:17547. | LEAK OXPHOS ET | N NS | Homogenate | Mouse | Nervous system |
Smenes 2018 Interact Cardiovasc Thorac Surg | 2018 | Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
Santos Bertolini 2018 Thesis | 2018 | Santos Bertolini M (2018) Functional study of MICU1 and MICU2 proteins in calcium signaling of Trypanosoma cruzi. Master's Thesis 108. | LEAK OXPHOS ET | S | Permeabilized cells | Protists | |
Qu 2018 FASEB J | 2018 | Qu C, Zhang S, Wang W, Li M, Wang Y, van der Heijde-Mulder M, Shokrollahi E, Hakim MS, Raat NJH, Peppelenbosch MP, Pan Q (2018) Mitochondrial electron transport chain complex III sustains hepatitis E virus replication and represents an antiviral target. FASEB J 33:1008-19. | LEAK ROUTINE | CIV ROX | Intact cells | Human | Liver |
Francisco 2018 J Neurochem | 2018 | Francisco A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. J Neurochem 147:663-77. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Nervous system |
Martins 2018 Oxid Med Cell Longev | 2018 | Martins IK, de Carvalho NR, Macedo GE, Rodrigues NR, Ziech CC, Vinadé L, Filho VMB, Menezes IA, Franco J, Posser T (2018) Anacardium microcarpum promotes neuroprotection dependently of AKT and ERK phosphorylation but does not prevent mitochondrial damage by 6-OHDA. Oxid Med Cell Longev 2018:2131895. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Chicken | Nervous system |
Zhou 2018 Cell Death Dis | 2018 | Zhou C, Sun H, Zheng C, Gao J, Fu Q, Hu N, Shao X, Zhou Y, Xiong J, Nie K, Zhou H, Shen L, Fang H, Lyu J (2018) Oncogenic HSP60 regulates mitochondrial oxidative phosphorylation to support Erk1/2 activation during pancreatic cancer cell growth. Cell Death Dis 9:161. | LEAK ROUTINE | ROX | Intact cells | Human | Islet cell;pancreas;thymus Other cell lines |
Salin 2018 Funct Ecol | 2018 | Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Funct Ecol DOI: 10.1111/1365-2435.13125. | LEAK OXPHOS | CIV NS ROX | Homogenate | Fishes | Liver |
Girard 2018 mSphere | 2018 | Girard RMBM, Crispim M, Alencar MB, Silber AM (2018) Uptake of L-alanine and its distinct roles in the bioenergetics of Trypanosoma cruzi. mSphere pii:e00338-18. | LEAK ET | Intact cells | Protists | ||
Wang 2018 Mol Med Rep | 2018 | Wang B, Li W, Fang H, Zhou H (2018) Hepatitis B virus infection is not associated with fatty liver disease: Evidence from a cohort study and functional analysis. Mol Med Rep 19:320-26. https://doi.org/10.3892/mmr.2018.9619 | LEAK ET | Intact cells | Human | Liver | |
Fuhrmann 2018 Cell Mol Life Sci | 2018 | Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67. | LEAK ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria Intact cells | Human | |
Braz-Mota 2018 Sci Total Environ | 2018 | Braz-Mota S, Campos DF, MacCormack TJ, Duarte RM, Val AL, Almeida-Val VMF (2018) Mechanisms of toxic action of copper and copper nanoparticles in two Amazon fish species: Dwarf cichlid (Apistogramma agassizii) and cardinal tetra (Paracheirodon axelrodi). Sci Total Environ 630:1168-80. | LEAK OXPHOS ET | N NS ROX | Fishes | Lung;gill | |
Hecker 2018 Biochim Biophys Acta | 2018 | Hecker M, Sommer N, Foch S, Hecker A, Hackstein H, Witzenrath M, Weissmann N, Seeger W, Mayer K (2018) Resolvin E1 and its precursor 18R-HEPE restore mitochondrial function in inflammation. Biochim Biophys Acta 1863:1016-28. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Ruas 2018 Sci Rep | 2018 | Ruas JS, Siqueira-Santos ES, Rodrigues-Silva E, Castilho RF (2018) High glycolytic activity of tumor cells leads to underestimation of electron transport system capacity when mitochondrial ATP synthase is inhibited. https://doi.org/10.1038/s41598-018-35679-8 | LEAK ET ROUTINE | N | Permeabilized cells Intact cells | Human | Nervous system Other cell lines |
Bradley 2018 Biochim Biophys Acta | 2018 | Bradley RM, Bloemberg D, Aristizabal Henao JJ, Hashemi A, Mitchell AS, Fajardo VA, Bellissimo C, Mardian EB, Bombardier E, Paré MF, Moes KA, Stark KD, Tupling AR, Quadrilatero J, Duncan RE (2018) Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fiber type in extensor digitorum longus muscle. Biochim Biophys Acta 1863:700-11. | LEAK OXPHOS ET | N S CIV NS | Permeabilized tissue | Mouse | Skeletal muscle |
Piel 2018 Intensive Care Med Exp | 2018 | Piel S, Ehinger JK, Chamkha I, Frostner EÅ, Sjövall F, Elmér E, Hansson MJ (2018) Bioenergetic bypass using cell-permeable succinate, but not methylene blue, attenuates metformin-induced lactate production. Intensive Care Med Exp 6:22. | LEAK | S ROX | Intact cells | Human | Platelet Blood cells |
Keller 2018 Oxid Med Cell Longev | 2018 | Keller AC, Knaub LA, Scalzo RL, Hull SE, Johnston AE, Walker LA, Reusch JEB (2018) Sepiapterin improves vascular reactivity and insulin-stimulated glucose in wistar rats. Oxid Med Cell Longev 2018:7363485. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Rat | Endothelial;epithelial;mesothelial cell |
Hancock 2018 Elife | 2018 | Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Heart |
Dabbaghizadeh 2018 PLOS ONE | 2018 | Dabbaghizadeh A, Morrow G, Amer YO, Chatelain EH, Pichaud N, Tanguay RM (2018) Identification of proteins interacting with the mitochondrial small heat shock protein Hsp22 of Drosophila melanogaster: Implication in mitochondrial homeostasis. PLOS ONE 13:e0193771. | LEAK ROUTINE ET | ROX | Intact cells | Human | HeLa |
Toledo 2018 Obesity (Silver Spring) | 2018 | Toledo FGS, Dubé JJ, Goodpaster BH, Stefanovic-Racic M, Coen PM, DeLany JP (2018) Mitochondrial respiration is associated with lower energy expenditure and lower aerobic capacity in African American women. Obesity (Silver Spring) 26:903-9. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Zhang 2018 Aging Dis | 2018 | Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue Homogenate | Rat | Nervous system |
Miklikova 2018 Physiol Res | 2018 | Miklíková M, Jarkovská D, Čedíková M, Švíglerová J, Kuncová J, Nalos L, Kubíková T, Liška V, Holubová M, Lysák D, Králíčková M, Vištejnová L, Štengl M (2018) Beneficial effects of mesenchymal stem cells on adult porcine cardiomyocytes in non-contact co-culture. Physiol Res 67:619-31. | LEAK ROUTINE ET | Intact cells | Pig | Heart | |
Rajasekaran 2018 FASEB J | 2018 | Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Mouse | Liver |
McWilliams 2018 Open Biol | 2018 | McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK (2018) Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol 8:180108. | LEAK OXPHOS ET | N | Homogenate | Mouse | Nervous system |
D'Souza 2018 J Lipid Res | 2018 | D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17. | LEAK OXPHOS | F N S ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Schiffer 2018 PLoS One | 2018 | Schiffer TA, Christensen M, Gustafsson H, Palm F (2018) The effect of inactin on kidney mitochondrial function and production of reactive oxygen species. PLoS One 13:e0207728. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Kidney |
Becker 2018 EMBO Rep | 2018 | Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Liver Fat |
Boeck 2018 Psychoneuroendocrinology | 2018 | Boeck C, Gumpp AM, Calzia E, Radermacher P, Waller C, Karabatsiakis A, Kolassa IT (2018) The association between cortisol, oxytocin, and immune cell mitochondrial oxygen consumption in postpartum women with childhood maltreatment. Psychoneuroendocrinology 96:69-77. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Paech 2018a Toxicology | 2018 | Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44. | LEAK OXPHOS ET | N S DQ CIV ROX | Permeabilized cells Isolated mitochondria | Human Mouse | Liver Other cell lines |
Houghton 2018 Free Radic Biol Med | 2018 | Houghton MJ, Kerimi A, Tumova S, Boyle JP, Williamson G (2018) Quercetin preserves redox status and stimulates mitochondrial function in metabolically-stressed HepG2 cells. Free Radic Biol Med 129:296-309. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Pamenter 2018 PLoS One | 2018 | Pamenter ME, Lau GY, Richards JG (2018) Effects of cold on murine brain mitochondrial function. PLoS One 13:e0208453. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Song 2018 Proc Natl Acad Sci U S A | 2018 | Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G (2018) Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes. Proc Natl Acad Sci U S A 115:1576-81. | LEAK OXPHOS ET | N S NS | Intact cells | Rat | Heart |
Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | LEAK ROUTINE OXPHOS ET | F S Gp | Permeabilized cells Intact cells | Human | Other cell lines Fibroblast |
Manakov 2018 J Physiol Biochem | 2018 | Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Rat | Heart |
Van Den Brink 2018 PLoS Genet | 2018 | Van Den Brink DM, Cubizolle A, Chatelain G, Davoust N, Girard V, Johansen S, Napoletano F, Dourlen P, Guillou L, Angebault-Prouteau C, Bernoud-Hubac N, Guichardant M, Brabet P, Mollereau B (2018) Physiological and pathological roles of FATP-mediated lipid droplets in Drosophila and mice retina. PLoS Genet 14:e1007627. | LEAK OXPHOS | F N S NS | Permeabilized cells | Mouse | Endothelial;epithelial;mesothelial cell |
Singh 2018 Arch Toxicol | 2018 | Singh F, Zoll J, Duthaler U, Charles AL, Panajatovic MV, Laverny G, McWilliams TG, Metzger D, Geny B, Krähenbühl S, Bouitbir J (2018) PGC-1β modulates statin-associated myotoxicity in mice. Arch Toxicol 93:487-504. | OXPHOS LEAK | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Scaini 2018 Eur Neuropsychopharmacol | 2018 | Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines Lymphocyte |
Kamunde 2018 Free Radic Biol Med | 2018 | Kamunde C, Sharaf M, MacDonald N (2018) H2O2 metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48. | LEAK | N ROX | Isolated mitochondria | Fishes | Heart Liver |
Sowton 2018 Biochem Biophys Res Commun | 2018 | Sowton AP, Millington-Burgess SL, Murray AJ, Harper MT (2018) Rapid kinetics of changes in oxygen consumption rate in thrombin-stimulated platelets measured by high-resolution respirometry. Biochem Biophys Res Commun 503:2721-27. | LEAK | Intact cells | Human | Platelet Blood cells | |
Fischer 2018 BMC Musculoskelet Disord | 2018 | Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Martins 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Martins EL, Ricardo JC, de-Souza-Ferreira E, Camacho-Pereira J, Ramos-Filho D, Galina A (2018) Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles. Comp Biochem Physiol B Biochem Mol Biol 217:40-50. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Machado-Neto 2018 Cell Death Dis | 2018 | Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Other cell lines |
Boeck 2018 Sci Rep | 2018 | Boeck C, Salinas-Manrique J, Calzia E, Radermacher P, von Arnim CAF, Dietrich DE, Kolassa IT, Karabatsiakis A (2018) Targeting the association between telomere length and immunocellular bioenergetics in female patients with Major Depressive Disorder. Sci Rep 8:9419. | LEAK ROUTINE ET | N ROX | Intact cells | Human | Blood cells |
Sant'Anna-Silva 2018 Front Oncol | 2018 | Sant'Anna-Silva ACB, Santos GC, Campos SPC, Oliveira Gomes AM, Pérez-Valencia JA, Rumjanek FD (2018) Metabolic profile of oral squamous carcinoma cell lines relies on a higher demand of lipid metabolism in metastatic cells. Front Oncol 8:13. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines Fibroblast |
Garcia-Roche 2018 Redox Biol | 2018 | García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12. | LEAK OXPHOS ET | N NS ROX S | Permeabilized tissue | Rat Bovines | Liver |
Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | LEAK ROUTINE OXPHOS ET | F N S DQ NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Park 2018 J Clin Invest | 2018 | Park H, He A, Tan M, Johnson JM, Dean JM, Pietka TA, Chen Y, Zhang X, Hsu FF, Razani B, Funai K, Lodhi IJ (2018) Peroxisome-derived lipids regulate adipose thermogenesis by mediating cold-induced mitochondrial fission. J Clin Invest 129:694-711. | OXPHOS ET LEAK | F N S | Permeabilized tissue | Mouse | Fat |
Boutoual 2018 Sci Rep | 2018 | Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Cardinale 2018 Thesis | 2018 | Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99. | LEAK OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Human | Skeletal muscle |
Rodrigues 2018 Free Radic Biol Med | 2018 | Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Drosophila | |
Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Wang 2018 Cell Physiol Biochem | 2018 | Wang P, Hu Y, Yao D, Li Y (2018) Omi/HtrA2 regulates a aitochondria-dependent apoptotic pathway in a murine model of septic encephalopathy. Cell Physiol Biochem 49:2163-73. | LEAK OXPHOS | N S CIV | Rat | Nervous system | |
Einer 2018 Cell Mol Gastroenterol Hepatol | 2018 | Einer C, Leitzinger C, Lichtmannegger J, Eberhagen C, Rieder T, Borchard S, Wimmer R, Denk G, Popper B, Neff F, Polishchuk EV, Polishchuk RS, Hauck SM, von Toerne C, Müller JC, Karst U, Baral BS, DiSpirito AA, Kremer AE, Semrau J, Weiss KH, Hohenester S, Zischka H (2018) A high calorie diet aggravates mitochondrial dysfunction and triggers severe liver damage in Wilson disease rats. Cell Mol Gastroenterol Hepatol 7:571-96. | LEAK OXPHOS ET | S | Isolated mitochondria | Rat | Liver |
Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
Ravasz 2018 Biochim Biophys Acta | 2018 | Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24. | LEAK OXPHOS | F N DQ | Isolated mitochondria | Mouse | Liver |
Kovalcikova 2018 Thesis | 2018 | Kovalčíková J (2018) Functional characterisation of new components of mitochondrial proteome. PhD Thesis p104. | LEAK OXPHOS ET | N NS | Homogenate | Mouse Rat | Heart Liver |
Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | ROUTINE OXPHOS ET LEAK | N S | Permeabilized cells Intact cells | Mouse | Lymphocyte |
Meinild Lundby 2018 Acta Physiol (Oxf) | 2018 | Meinild Lundby AK, Jacobs RA, Gehrig S, de Leur J, Hauser M, Bonne TC, Flück D, Dandanell S, Kirk N, Kaech A, Ziegler U, Larsen S, Lundby C (2018) Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. Acta Physiol (Oxf) 222, e12905. | OXPHOS LEAK ET | NS F N CIV | Permeabilized tissue | Human | Skeletal muscle |
Clere-Jehl 2018 Shock | 2018 | Clere-Jehl R, Helms J, Kassem M, Le Borgne P, Delabranche X, Charles AL, Geny B, Meziani F, Bilbault P (2018) Septic shock alters mitochondrial respiration of lymphoid cell-lines and human peripheral blood mononuclear cells: the role of plasma. Shock 51:97-104. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
Rivas 2018 Am J Physiol Endocrinol Metab | 2018 | Rivas E, Herndon DN, Porter C, Meyer W, Suman OE. (2018) Short-term metformin and exercise training effects on strength, aerobic capacity, glycemic control, and mitochondrial function in children with burn injury.. Am J Physiol Endocrinol Metab. 314(3):E232-E240. | LEAK OXPHOS | Permeabilized tissue | Human | Skeletal muscle | |
Banerjee 2018 Stem Cells Int | 2018 | Banerjee A, Lindenmair A, Steinborn R, Dumitrescu SD, Hennerbichler S, Kozlov AV, Redl H, Wolbank S, Weidinger A (2018) Oxygen tension strongly influences metabolic parameters and the release of interleukine-6 of human amniotic mesenchymal stromal cells in vitro. Stem Cells Int 2018:9502451. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell Genital | |
Falcao-Tebas 2018 J Physiol | 2018 | Falcão-Tebas F, Kuang J, Arceri C, Kerris JP, Andrikopoulos S, Marin EC, McConell GK (2018) Four weeks of exercise early in life reprograms adult skeletal muscle insulin resistance caused by paternal high fat diet. J Physiol 597:121-36. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Zimin 2018 Br J Anaesth | 2018 | Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32. | OXPHOS LEAK | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Pileggi 2018 Free Radic Biol Med | 2018 | Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Kjeld 2018 PLoS One | 2018 | Kjeld T, Stride N, Gudiksen A, Hansen EG, Arendrup HC, Horstmann PF, Zerahn B, Jensen LT, Nordsborg N, Bejder J, Halling JF (2018) Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers. PLoS One 13:e0201401. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | LEAK ET ROUTINE OXPHOS | N S | Homogenate Intact cells | Mouse | Fibroblast |
Goncalves 2018 Life Sci | 2018 | Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sci 193:234-41. | LEAK OXPHOS | N S NS ROX | Homogenate | Mouse | Liver |
Hayward 2018 Thesis | 2018 | Hayward L (2018) The effect of anoxia on mitochondrial function in a hibernator (Ictidomys tridecemlineatus). Master's Thesis 57. | OXPHOS LEAK | N NS | Isolated mitochondria | Other mammals | Liver |
Oemer 2018 Proc Nat Acad Sci U S A | 2018 | Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
Rodriguez-Nuevo 2018 EMBO J | 2018 | Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Gao 2018 Free Radic Biol Med | 2018 | Gao JL, Zhao J, Zhu HB, Peng X, Zhu JX, Ma MH, Fu Y, Hu N, Tai Y, Xuan XC, Dong DL (2018) Characterizations of mitochondrial uncoupling induced by chemical mitochondrial uncouplers in cardiomyocytes. Free Radic Biol Med 124:288-98. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
Dandanell 2018 Scand J Med Sci Sports | 2018 | Dandanell S, Meinild-Lundby AK, Andersen AB, Lang PF, Oberholzer L, Keiser S, Robach P, Larsen S, Rønnestad BR, Lundby C (2018) Determinants of maximal whole-body fat oxidation in elite cross-country skiers: role of skeletal muscle mitochondria. Scand J Med Sci Sports 28:2494-504. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Campbell 2018 Free Radic Biol Med | 2018 | Campbell MD, Duan J, Samuelson AT, Gaffrey MJ, Wang L, Bammler TK, Moore RJ, White CC, Kavanagh TJ, Voss JG, Szeto HH, Rabinovitch PS, Qian WJ, Marcinek DJ (2018) Improving mitochondrial function with SS-31 reverses age-related redox stress and improves exercise tolerance in aged mice. Free Radic Biol Med 134:268-81. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Cecatto 2018 FEBS J | 2018 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca2+ homeostasis in the heart. FEBS J 285:1437-55. | LEAK OXPHOS ET | N S | Permeabilized cells Permeabilized tissue Isolated mitochondria | Rat | Heart Other cell lines |
Bhaskaran 2018 EMBO Rep | 2018 | Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009. | LEAK OXPHOS | N S NS | Mouse | Fat | |
Martinez 2018 Arch Biochem Biophys | 2018 | Martínez JH, Fuentes F, Vanasco V, Alvarez S, Alaimo A, Cassina A, Coluccio Leskow F, Velazquez F (2018) Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment. Arch Biochem Biophys 651:1-12. | LEAK OXPHOS ET | N S ROX | Isolated mitochondria | Rat | Nervous system |
Musi 2018 Aging Cell | 2018 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | F N S NS | Homogenate | Mouse | Nervous system |
Ko 2018 Pflugers Arch | 2018 | Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75. | LEAK OXPHOS | N ROX | Isolated mitochondria | Rat | Heart |
Groennebaek 2018 Front Physiol | 2018 | Groennebaek T, Jespersen NR, Jakobsgaard JE, Sieljacks P, Wang J, Rindom E, Musci RV, Bøtker HE, Hamilton KL, Miller BF, de Paoli FV, Vissing K (2018) Skeletal muscle mitochondrial protein synthesis and respiration increase with low-load blood flow restricted as well as high-load resistance training. Front Physiol 9:1796. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Briones-Herrera 2018 Food Chem Toxicol | 2018 | Briones-Herrera A, Avila-Rojas SH, Aparicio-Trejo OE, Cristóbal M, León-Contreras JC, Hernández-Pando R, Pinzón E, Pedraza-Chaverri J, Sánchez-Lozada LG, Tapia E (2018) Sulforaphane prevents maleic acid-induced nephropathy by modulating renal hemodynamics, mitochondrial bioenergetics and oxidative stress. Food Chem Toxicol 115:185-97. | LEAK OXPHOS | N NS S | Isolated mitochondria | Rat | Kidney |
Aparicio-Trejo 2018 Free Radic Biol Med | 2018 | Aparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96. | LEAK OXPHOS | N S NS ROX | Intact cells Isolated mitochondria | Rat | Kidney |
Lander 2018 J Biol Chem | 2018 | Lander N, Chiurillo MA, Bertolini MS, Storey M, Vercesi AE, Docampo R (2018) Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi. J Biol Chem 293:17402-17. | LEAK OXPHOS ET | N S | Permeabilized cells | Protists | |
Wilmanns 2018 Mol Metab | 2018 | Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Mouse | Heart |
Zhang 2018 Cardiovasc Diabetol | 2018 | Zhang X, Zhang Z, Yang Y, Suo Y, Liu R, Qiu J, Zhao Y, Jiang N, Liu C, Tse G, Li G, Liu T (2018) Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits. Cardiovasc Diabetol 17:160. | OXPHOS LEAK | N | Isolated mitochondria | Rabbit | Heart |
Zhang 2018 J Mol Cell Cardiol | 2018 | Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria | Mouse | Heart |
Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | LEAK OXPHOS ET | N S DQ CIV ROX NS | Isolated mitochondria | Mouse | Liver |
Alston 2018 Am J Hum Genet | 2018 | Alston CL, Heidler J, Dibley MG, Kremer LS, Taylor LS, Fratter C, French CE, Glasgow RIC, Feichtinger RG, Delon I, Pagnamenta AT, Dolling H, Lemonde H, Aiton N, Bjørnstad A, Henneke L, Gärtner J, Thiele H, Tauchmannova K, Quaghebeur G, Houstek J, Sperl W, Raymond FL, Prokisch H, Mayr JA, McFarland R, Poulton J, Ryan MT, Wittig I, Henneke M, Taylor RW (2018) Bi-allelic mutations in NDUFA6 establish its role in early-onset isolated mitochondrial complex I deficiency. Am J Hum Genet 103:592-601. | LEAK ET | Intact cells | Human | Fibroblast | |
Niu 2018 Cancer Metab | 2018 | Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Human | HeLa |
Dechandt 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Dechandt CR, Vicentini TM, Lanfredi GP, da Silva RMP Jr, Espreafico EM, de Oliveira JAC, Faça VM, Garcia-Cairasco N, Alberici LC (2018) The highly efficient power house in the Wistar Audiogenic Rat (WAR), an epileptic rat strain. Am J Physiol Regul Integr Comp Physiol 316:R243-R254. | LEAK OXPHOS ET | N ROX | Permeabilized tissue Isolated mitochondria | Rat | Heart Skeletal muscle Liver |
Kahancova 2018 FEBS Lett | 2018 | Kahancova A, Sklenar F, Jezek P, Dlaskova A (2018) Regulation of glucose-stimulated insulin secretion by ATPase Inhibitory Factor 1 (IF1). FEBS Lett 592:999-1009. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Other cell lines |
Kappler 2018 Thesis | 2018 | Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Skeletal muscle Liver Other cell lines |
Karlsson 2018 J Neurotrauma | 2018 | Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T (2018) Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. J Neurotrauma 36:14-24. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Christensen 2018 Diabetes Metab Res Rev | 2018 | Christensen M, Schiffer TA, Gustafsson H, Krag SP, Nørregaard R, Palm F (2018) Metformin attenuates renal medullary hypoxia in diabetic nephropathy through uncoupling protein-2 inhibition. Diabetes Metab Res Rev 21:e3091. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Kidney |
Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Human | Lung;gill Fibroblast |
Davis 2018 FASEB J | 2018 | Davis RAH, Deemer SE, Bergeron JM, Little JT, Warren JL, Fisher G, Smith DL Jr, Fontaine KR, Dickinson SL, Allison DB, Plaisance EP (2018) Dietary R, S-1,3-butanediol diacetoacetate reduces body weight and adiposity in obese mice fed a high-fat diet. FASEB J 33:2409-21. | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Bryant 2018 Thesis | 2018 | Bryant HJ (2018) The role of mitochondrial uncoupling in temperature responses in Atlantic killifish, Fundulus heteroclitus. Master's Thesis p126. | LEAK OXPHOS ET | F S | Isolated mitochondria | Fishes | Nervous system Liver Fat |
Bricambert 2018 Nat Commun | 2018 | Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092. | LEAK OXPHOS ET | N S | Homogenate | Mouse | Liver |
Lee 2018 Reprod Sci | 2018 | Lee HC, Lin SC, Wu MH, Tsai SJ (2018) Induction of pyruvate dehydrogenase kinase 1 by hypoxia alters cellular metabolism and inhibits apoptosis in endometriotic stromal cells. Reprod Sci 26:734-44. | LEAK ROUTINE | ROX | Intact cells | Human | Genital |
Doucet 2018 Mol Pharmacol | 2018 | Doucet MS, Jougleux JL, Poirier SJ, Cormier M, Leger JL, Surette ME, Pichaud N, Touaibia M, Boudreau LH (2018) Identification of peracetylated quercetin as a selective 12-lipoxygenase pathway inhibitor in human platelets. Mol Pharmacol 95:139-50. | LEAK ROUTINE ET | ROX | Intact cells | Human | Platelet Blood cells |
Du 2018 Environ Sci Technol | 2018 | Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11. | LEAK ET | N S NS | Isolated mitochondria | Fishes | Liver |
Friederich-Persson 2018 Acta Physiol (Oxf) | 2018 | Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Kidney |
Remor 2018 Mol Neurobiol | 2018 | Remor AP, da Silva RA, de Matos FJ, Glaser V, de Paula Martins R, Ghisoni K, da Luz Scheffer D, Andia DC, Portinho D, de Souza AP, de Oliveira PA, Prediger RD, Torres AI, Linhares RMM, Walz R, Ronsoni MF, Hohl A, Rafacho A, Aguiar AS Jr, De Paul AL, Latini A (2018) Chronic metabolic derangement-induced cognitive deficits and neurotoxicity are associated with REST inactivation. Mol Neurobiol 56:1539-57. | LEAK OXPHOS | N | Intact cells | Rat | Nervous system |
Lima 2018 Biochem Cell Biol | 2018 | Lima T, Silveira L (2018) A microplate assay for measuring cell death in C2C12 cells. Biochem Cell Biol 96:702-6. | LEAK ET | F | Intact cells | Mouse | Skeletal muscle Other cell lines |
Konopka 2018 Aging Cell | 2018 | Konopka AR, Laurin JL, Schoenberg HM, Reid JJ, Castor WM, Wolff CA, Musci RV, Safairad OD, Linden MA, Biela LM, Bailey SM, Hamilton KL, Miller BF (2018) Metformin inhibits mitochondrial adaptations to aerobic exercise training in older adults. Aging Cell 18:e12880. | OXPHOS ET LEAK | F N NS S ROX | Permeabilized tissue | Human | Skeletal muscle |
Urazov 2018 Sovrem Tekhnologii Med | 2018 | Urazov MD, Astrakhanova TA, Usenko AV, Mishchenko TA, Schelchkova NA, Kravchenko GA, Vedunova MV, Mitroshina EV (2018) New aspects of central nervous system adaptation to prenatal hypoxia. Sovrem Tekhnologii Med 10:60-68. | OXPHOS LEAK | N S NS | Isolated mitochondria | Mouse | Nervous system |
Mancini 2017 Thesis | 2018 | Mancini G (2017) Colesterol dietético e doença de Alzheimer em modelos experimentais: avaliação da resposta sináptica, mitocondrial e comportamental. Doctoral Thesis p118. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system |
Krug 2018 Thesis | 2018 | Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136. | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Intact cells Permeabilized cells | Rat | Other cell lines |
Chung 2018 J Exp Biol | 2018 | Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458. | LEAK OXPHOS ET | F N S CIV NS ROX | Isolated mitochondria | Fishes | Liver |
Scalzo 2018 Physiol Rep | 2018 | Scalzo RL, Knaub LA, Hull SE, Keller AC, Hunter K, Walker LA, Reusch JEB (2018) Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats. Physiol Rep 6:e13754. | LEAK OXPHOS ET | F NS Other combinations | Permeabilized tissue | Rat | Heart |
Goncalves 2018 Neurotoxicology | 2018 | Gonçalves DF, Courtes AA, Hartmann DD, da Rosa PC, Oliveira DM, Soares FAA, Dalla Corte CL (2018) 6-Hydroxydopamine induces different mitochondrial bioenergetics response in brain regions of rat. Neurotoxicology 70:1-11. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Nervous system |
Warnsmann 2018 Mech Ageing Dev | 2018 | Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58. | LEAK OXPHOS ET | N | Isolated mitochondria | Fungi | |
Pacheco-Velazquez 2018 Mol Pharm | 2018 | Pacheco-Velázquez SC, Robledo-Cadena DX, Hernández-Reséndiz I, Gallardo-Pérez JC, Moreno-Sánchez R, Rodríguez-Enríquez S (2018) Energy metabolism drugs block triple negative breast metastatic cancer cell phenotype. Mol Pharm 15:2151-64. | LEAK | Human | Genital Other cell lines | ||
Cooper 2018 Exp Physiol | 2018 | Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Mouse | Nervous system |
Reyes 2018 EMBO Mol Med | 2018 | Reyes A, Melchionda L, Burlina A, Robinson AJ, Ghezzi D, Zeviani M (2018) Mutations in TIMM50 compromise cell survival in OxPhos-dependent metabolic conditions. EMBO Mol Med 10:e8698. | LEAK ET | ROX | Intact cells | Human | Fibroblast |
Matsumoto 2018 Circulation | 2018 | Matsumoto J, Takada S, Kinugawa S, Furihata T, Nambu H, Kakutani N, Tsuda M, Fukushima A, Yokota T, Tanaka S, Takahashi H, Watanabe M, Hatakeyama S, Matsumoto M, Nakayama KI, Otsuka Y, Sabe H, Tsutsui H, Anzai T (2018) Brain-derived neurotrophic factor improves limited exercise capacity in mice with heart failure. Circulation 138:2064-66. | LEAK ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Marie 2018 Cell Death Dis | 2018 | Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis 9:287. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Endothelial;epithelial;mesothelial cell | |
Jang 2018 Shock | 2018 | Jang DH, Orloski CJ, Owiredu S, Shofer FS, Greenwood JC, Eckmann DM (2018) Alterations in mitochondrial function in blood cells obtained from patients with sepsis presenting to an emergency department. Shock 51:580-84. | LEAK ROUTINE ET | ROX | Human | Blood cells | |
Stepanova 2018 J Cereb Blood Flow Metab | 2018 | Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab 39:1790-802. | OXPHOS ET LEAK | N S ROX | Isolated mitochondria | Rat | Nervous system |
Champigny 2018 Mar Drugs | 2018 | Champigny CM, Cormier RPJ, Simard CJ, St-Coeur PD, Fortin S, Pichaud N (2018) Omega-3 monoacylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453. | LEAK OXPHOS ET | N S NS ROX Gp | Permeabilized tissue | Drosophila | |
Kuehn 2018 Biochem Pharmacol | 2018 | Kühn B, Brat C, Fettel J, Hellmuth N, Maucher IV, Bulut U, Hock KJ, Grimmer J, Manolikakes G, Rühl M, Kühn A, Zacharowski K, Matrone C, Urbschat A, Roos J, Steinhilber D, Maier TJ (2018) Anti-inflammatory nitro-fatty acids suppress tumor growth by triggering mitochondrial dysfunction and activation of the intrinsic apoptotic pathway in colorectal cancer cells. Biochem Pharmacol 155:48-60. | LEAK ET | CIV | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Treberg 2018 Redox Biol | 2018 | Treberg JR, Braun K, Selseleh P (2018) Mitochondria can act as energy-sensing regulators of hydrogen peroxide availability. Redox Biol 20:483-88. | LEAK OXPHOS ET | S | Isolated mitochondria | Rat | Skeletal muscle |
Fox 2018 Thesis | 2018 | Fox JC (2018) FROST450, a novel microtubule targeting agent: resistance and cross-resistance in an ovarian cancer cell line. Bachelor's Thesis 27. | LEAK OXPHOS ET | N NS ROX | Intact cells | Human | Genital |
Tai 2018 Acta Pharm Sin B | 2018 | Tai Y, Li L, Peng X, Zhu J, Mao X, Qin N, Ma M, Huo R, Bai Y, Dong D (2018) Mitochondrial uncoupler BAM15 inhibits artery constriction and potently activates AMPK in vascular smooth muscle cells. Acta Pharm Sin B 8:909-18. | LEAK ET | ROX | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell |
Haschka 2018 Mov Disord | 2018 | Haschka D, Volani C, Stefani A, Tymoszuk P, Mitterling T, Holzknecht E, Heidbreder A, Coassin S, Sumbalova Z, Seifert M, Dichtl S, Theurl I, Gnaiger E, Kronenberg F, Frauscher B, Högl B, Weiss G (2018) Association of mitochondrial iron deficiency and dysfunction with idiopathic restless legs syndrome. Mov Disord 34:114-23. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Lymphocyte |
Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Rubio-Villena 2018 Hum Mol Genet | 2018 | Rubio-Villena C, Viana R, Bonet J, Garcia-Gimeno MA, Casado M, Heredia M, Sanz P (2018) Astrocytes: new players in progressive myoclonus epilepsy of Lafora type. Hum Mol Genet 27:1290-1300. | LEAK ROUTINE ET | ROX | Mouse | Nervous system | |
Marinho 2018 Evid Based Complement Alternat Med | 2018 | Marinho PC, Vieira AB, Pereira PG, Rabelo K, Ciambarella BT, Nascimento ALR, Cortez E, Moura AS, Guimarães FV, Martins MA, Barquero G, Ferreira RN, de Carvalho JJ (2018) Capybara oil improves hepatic mitochondrial dysfunction, steatosis, and inflammation in a murine model of nonalcoholic fatty liver disease. Evid Based Complement Alternat Med 2018:4956079. | LEAK OXPHOS | Intact cells | Mouse | Liver | |
Burney 2018 Thesis | 2018 | Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50. | LEAK ROUTINE OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells Intact cells | Rat | Other cell lines |
Angebault 2018 Sci Signal | 2018 | Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C (2018) ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome. Sci Signal 11:eaaq1380. | LEAK OXPHOS | N S NS | Permeabilized cells | Human | Fibroblast |
MacMillan-Crow 2018 Intern Med Rev (Wash D C) | 2018 | MacMillan-Crow LA, Mayeux PR (2018) Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. Intern Med Rev (Wash D C) 4. | OXPHOS LEAK | N S ROX | Permeabilized tissue | Mouse | Kidney |
Sokolov 2018 Mitochondrion | 2018 | Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Molluscs | Lung;gill |
Larsen 2018 Physiol Rep | 2018 | Larsen S, Lundby AM, Dandanell S, Oberholzer L, Keiser S, Andersen AB, Haider T, Lundby C (2018) Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. Physiol Rep 6:e13793. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Fisher-Wellman 2018 Cell Rep | 2018 | Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606. | LEAK OXPHOS | F N S | Isolated mitochondria | Mouse | Heart Skeletal muscle |
Chen 2018 iScience | 2018 | Chen YC, Cheng TH, Lin WL, Chen CL, Yang WY, Blackstone C, Chang CR (2018) Srv2 Is a pro-fission factor that modulates yeast mitochondrial morphology and respiration by regulating actin assembly. iScience 11:305-17. | LEAK ROUTINE ET | ROX | Intact cells | Saccharomyces cerevisiae | |
Blunsom 2018 Biochim Biophys Acta | 2018 | Blunsom NJ, Gomez-Espinosa E, Ashlin TG, Cockcroft S (2018) Mitochondrial CDP-diacylglycerol synthase activity is due to the peripheral protein, TAMM41 and not due to the integral membrane protein, CDP-diacylglycerol synthase 1. Biochim Biophys Acta 1863:284-98. | LEAK ROUTINE ET | ROX | Intact cells | Rat | Heart |
Kriel 2018 Sci Rep | 2018 | Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348. | LEAK OXPHOS ET ROUTINE | N ROX | Permeabilized cells | Human | Nervous system Other cell lines |
Bialas 2018 Int J Chron Obstruct Pulmon Dis | 2018 | Białas AJ, Siewiera K, Watała C, Rybicka A, Grobelski B, Kośmider L, Kurek J, Miłkowska-Dymanowska J, Piotrowski WJ, Górski P (2018) Mitochondrial functioning abnormalities observed in blood platelets of chronic smoke-exposed guinea pigs – a pilot study. Int J Chron Obstruct Pulmon Dis 13:3707—17 . | LEAK ROUTINE ET | ROX | Intact cells | Guinea pig | Platelet |
Gratl 2018 Thesis | 2018 | Gratl A (2018) High-resolution respirometry for measurement of mitochondrial function in PAD patients before and after revascularisation. PhD Thesis 69. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Cardinale 2018 Physiol Rep | 2018 | Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
Dias 2018 Anal Biochem | 2018 | Dias C, Lourenco CF, Barbosa RM, Laranjinha J, Ledo A (2018) Analysis of respiratory capacity in brain tissue preparations: high-resolution respirometry for intact hippocampal slices. Anal Biochem 551:43-50. | LEAK ROUTINE ET | ROX | Intact cells | Mouse Rat | Nervous system |
Casal 2018 J Anim Sci | 2018 | Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43. | LEAK OXPHOS ET | N S ROX | Intact cells | Bovines | Liver |
Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. | LEAK OXPHOS | F N NS ROX | Permeabilized tissue Isolated mitochondria | Human Mouse | Heart |
Thompson 2018 EMBO Mol Med | 2018 | Thompson K, Mai N, Oláhová M, Scialó F, Formosa LE, Stroud DA, Garrett M, Lax NZ, Robertson FM, Jou C, Nascimento A, Ortez C, Jimenez-Mallebrera C, Hardy SA, He L, Brown GK, Marttinen P, McFarland R, Sanz A, Battersby BJ, Bonnen PE, Ryan MT, Chrzanowska-Lightowlers ZM, Lightowlers RN, Taylor RW (2018) OXA1L mutations cause mitochondrial encephalopathy and a combined oxidative phosphorylation defect. EMBO Mol Med 10:e9060. | LEAK OXPHOS | N CIV ROX Gp Other combinations | Homogenate | Drosophila | |
Holloway 2018 Cell Rep | 2018 | Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC (2018) Age-associated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Ramil 2018 Thesis | 2018 | Ramil LR, Gulbinas A, Cesna V (2018) “HIPEC” hyperthermic intraperitoneal chemotherapy. Evaluation of intraperitoneal free cancer cells. Master's Thesis. | OXPHOS LEAK | N S | Isolated mitochondria | Human | Endothelial;epithelial;mesothelial cell |
Lo 2018 Am J Physiol Renal Physiol | 2018 | Lo S, MacMillan-Crow LA, Parajuli N (2018) Renal cold storage followed by transplantation impairs proteasome function and subsequently mitochondrial protein homeostasis. Am J Physiol Renal Physiol 316:F42-F53. | OXPHOS LEAK | N S ROX | Permeabilized cells | Rat | Kidney Other cell lines |
De Lima Junior 2018 EBioMedicine | 2018 | De Lima Junior JC, Souza GF, Moura-Assis A, Gaspar RS, Gaspar JM, Rocha AL, Ferrucci DL, Lima TI, Victório SC, Bonfante ILP, Cavaglieri CR, Pareja JC, Brunetto SQ, Ramos CD, Geloneze B, Mori MA, Silveira LR, Segundo GRS, Ropelle ER, Velloso LA (2018) Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency. EBioMedicine 39:436-47. | LEAK ET | N | Isolated mitochondria | Mouse | Fat |
Distefano 2018 J Cachexia Sarcopenia Muscle | 2018 | Distefano G, Standley RA, Zhang X, Carnero EA, Yi F, Cornnell HH, Coen PM (2018) Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. J Cachexia Sarcopenia Muscle 9:279-94. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Clarke 2018 Methods Mol Biol | 2018 | Clarke KJ, Porter RK (2018) The importance of calcium ions for determining mitochondrial glycerol-3-phosphate dehydrogenase activity when measuring uncoupling protein 1 (UCP1) function in mitochondria isolated from brown adipose tissue. Methods Mol Biol 1782:325-36. | LEAK | S Gp | Isolated mitochondria | Rat | Fat |
Dogan 2018 Cell Metab | 2018 | Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77. | LEAK OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Scarpelli 2018 J Pineal Res | 2018 | Scarpelli P, Almeida GT, Viçoso KL, Lima WR, Pereira LB, Meissner KA, Wrenger C, Rafaello A, Rizzuto R, Pozzan T, Garcia CRS (2018) Melatonin activate FIS1, DYN1 and DYN2 Plasmodium falciparum related-genes for mitochondria fission: mitoemerald-GFP as a tool to visualize mitochondria structure. J Pineal Res 66:e12484. | LEAK ROUTINE ET | Intact organism | |||
Yepez 2018 PLOS One | 2018 | Yépez VA, Kremer LS, Iuso A, Gusic M, Kopajtich R, Koňaříková E, Nadel A, Wachutka L, Prokisch H, Gagneur J (2018) OCR-Stats: Robust estimation and statistical testing of mitochondrial respiration activities using Seahorse XF Analyzer. https://doi.org/10.1371/journal.pone.0199938 | LEAK ROUTINE ET | Intact cells | |||
Lobo-Jarne 2018 Cell Rep | 2018 | Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99. | LEAK OXPHOS ET | N S NS ROX Gp | Permeabilized cells | Human | HEK Other cell lines |
De Godoy 2018 J Biol Chem | 2018 | de Godoy MA, Saraiva LM, de Carvalho LRP, Vasconcelos-Dos-Santos A, Beiral HJV, Ramos AB, Silva LRP, Leal RB, Monteiro VHS, Braga CV, de Araujo-Silva CA, Sinis LC, Bodart-Santos V, Kasai-Brunswick TH, Alcantara CL, Lima APCA, da Cunha-E Silva NL, Galina A, Vieyra A, De Felice FG, Mendez-Otero R, Ferreira ST (2018) Mesenchymal stem cells and cell-derived extracellular vesicles protect hippocampal neurons from oxidative stress and synapse damage induced by amyloid-β oligomers. J Biol Chem 293:1957-75. | LEAK ROUTINE ET | Intact cells | Rat | Nervous system | |
Mendes 2018 Mol Neurobiol | 2018 | Mendes Lima JP, Rayêe D, Silva-Rodrigues T, Ribeiro Paes Pereira P, Mendonca APM, Rodrigues-Ferreira C, Szczupak D, Fonseca A, Oliveira MF, Souza Lima FR, Lent R, Galina A, Uziel D (2018) Perinatal asphyxia and brain development: mitochondrial damage without anatomical or cellular losses. Mol Neurobiol doi.org/10.1007/s12035-018-1019-7. | LEAK ROUTINE ET | N NS ROX | Intact cells | Rat | Nervous system |
Gam 2018 Acta Diabetol | 2018 | Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Human | Genital |
Tsuda 2018 J Cachexia Sarcopenia Muscle | 2018 | Tsuda M, Fukushima A, Matsumoto J, Takada S, Kakutani N, Nambu H, Yamanashi K, Furihata T, Yokota T, Okita K, Kinugawa S, Anzai T (2018) Protein acetylation in skeletal muscle mitochondria is involved in impaired fatty acid oxidation and exercise intolerance in heart failure. J Cachexia Sarcopenia Muscle 9:844-59. | OXPHOS LEAK | F N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Wang 2018 J Nutr Biochem | 2018 | Wang Y, Fouret G, Bonafos B, Blachnio-Zabielska A, Leroy T, Crouzier D, Barea B, Gaillet S, Moro C, Lecomte J, Coudray C, Feillet-Coudray C (2018) Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats. J Nutr Biochem 64:182-97. | OXPHOS LEAK | N NS | Isolated mitochondria | Rat | Skeletal muscle |
Sirsat 2018 Comp Biochem Physiol A Mol Integr Physiol | 2018 | Sirsat SKG, Dzialowski EM (2018) Ontogeny of skeletal and cardiac muscle mitochondria oxygen fluxes in two breeds of chicken. Comp Biochem Physiol A Mol Integr Physiol 215:20-7. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Birds | Heart Skeletal muscle |
Razak 2018 RUMeS | 2018 | Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Nervous system |
Vatner 2018 Aging Cell | 2018 | Vatner DE, Zhang J, Oydanich M, Guers J, Katsyuba E, Yan L, Sinclair D, Auwerx J, Vatner SF (2018) Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751. | LEAK OXPHOS | N S NS | Intact cells | Mouse | Fat |
Khamoui 2018 J Dev Orig Health Dis | 2018 | Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Hedges 2018 FASEB J | 2018 | Hedges CP, Bishop DJ, Hickey AJR (2018) Voluntary wheel running prevents the acidosis-induced decrease in skeletal muscle mitochondrial reactive oxygen species emission. FASEB J 33:4996-5004. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Ziegler 2018 Cell | 2018 | Ziegler PK, Bollrath J, Pallangyo CK, Matsutani T, Canli Ö, De Oliveira T, Diamanti MA, Müller N, Gamrekelashvili J, Putoczki T, Horst D, Mankan AK, Öner MG, Müller S, Müller-Höcker J, Kirchner T, Slotta-Huspenina J, Taketo MM, Reinheckel T, Dröse S, Larner AC, Wels WS, Ernst M, Greten TF, Arkan MC, Korn T, Wirth D, Greten FR (2018) Mitophagy in intestinal epithelial cells triggers adaptive immunity during tumorigenesis. Cell 174:88-101. | LEAK ET | Intact cells | Mouse | Endothelial;epithelial;mesothelial cell | |
Komlodi 2018 J Bioenerg Biomembr | 2018 | Komlódi T, Geibl FF, Sassani M, Ambrus A, Tretter L (2018) Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr 50:355-365 | LEAK | S Gp | Isolated mitochondria | Guinea pig | Heart Nervous system |
De Moura Alvorcem 2018 Mitochondrion | 2018 | De Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, Da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2018) Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum. Mitochondrion 47:141-50. | LEAK OXPHOS ET | N S NS | Isolated mitochondria Intact cells | Rat | Nervous system |
Logan 2018 Thesis | 2018 | Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Zebrafish | Skeletal muscle |
Li 2018 Free Radic Biol Med | 2018 | Li H, Tang Z, Chu P, Song Y, Yang Y, Sun B, Niu M, Qaed E, Shopit A, Han G, Ma X, Peng J, Hu M, Tang Z (2018) Neuroprotective effect of phosphocreatine on oxidative stress and mitochondrial dysfunction induced apoptosis in vitro and in vivo: Involvement of dual PI3K/Akt and Nrf2/HO-1 pathways. Free Radic Biol Med 120:228-38. | LEAK ROUTINE ET | CIV | Intact cells | Rat | Nervous system Other cell lines |
Cecatto 2018 J Cell Biochem | 2018 | Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86. | LEAK OXPHOS ET | N | Permeabilized cells Permeabilized tissue | Rat | Heart Nervous system Liver |
Okerblom 2018 Proc Biol Sci | 2018 | Okerblom J, Fletes W, Patel HH, Schenk S, Varki A, Breen EC (2018) Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution. Proc Biol Sci 285:20181656. | OXPHOS LEAK | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Real-Hohn 2018 bioRxiv | 2018 | Real-Hohn A, Navegantes C, Ramos K, Ramos-Filho D, Cahuê F, Galina A, Salerno V (2018) Hexokinase: a central player in the synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations. bioRxiv doi: https://doi.org/10.1101/389668. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Jang 2018 Intensive Care Med Exp | 2018 | Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | Blood cells |
Mavroudis 2018 Eur J Cardiothorac Surg | 2018 | Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68. | LEAK ET OXPHOS | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Flis 2018 Oxid Med Cell Longev | 2018 | Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice. Oxid Med Cell Longev 5940748. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Skeletal muscle |
Ounpuu 2018 Biochem Cell Biol | 2018 | Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print]. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Pape 2018 Nutrients | 2018 | Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH (2018) Per-Arnt-Sim kinase (PASK) deficiency increases cellular respiration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990. | OXPHOS LEAK | NS | Permeabilized tissue | Mouse | Skeletal muscle Liver |
Chicco 2018 J Biol Chem | 2018 | Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Human | Skeletal muscle |
Stanford 2018 Cell Metab | 2018 | Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ (2018) 12,13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20. | LEAK OXPHOS ET | F ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
Liu 2018 J Periodontol | 2018 | Liu J, Zeng J, Wang X, Zheng M, Luan Q (2018) P53 mediates lipopolysaccharide-induced inflammation in human gingival fibroblasts. J Periodontol 89:1142-51. | LEAK ET | ROX | Intact cells | Human | Fibroblast |
Rocha 2018 J Physiol Biochem | 2018 | Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Rekuviene 2018 Thesis | 2018 | Rekuvienė E (2018) Effect of respiratory complex I inhibitors on mitochondrial permeability transition and cell viability during brain ischemia. Doctoral Dissertation 138. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Nervous system |
Touat 2018 J Clin Invest | 2018 | Touat M, Sourisseau T, Dorvault N, Chabanon RM, Garrido M, Morel D, Krastev DB, Bigot L, Adam J, Frankum JR, Durand S, Pontoizeau C, Souquère S, Kuo MS, Sauvaigo S, Mardakheh F, Sarasin A, Olaussen KA, Friboulet L, Bouillaud F, Pierron G, Ashworth A, Lombès A, Lord CJ, Soria JC, Postel-Vinay S (2018) DNA repair deficiency sensitizes lung cancer cells to NAD+ biosynthesis blockade. J Clin Invest 128:1671-87. | LEAK ROUTINE ET | Human | Lung;gill Other cell lines | ||
Lai 2018 Acta Physiol (Oxf) | 2018 | Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopulations from skeletal muscle: optimizing recovery and preserving integrity. Acta Physiol (Oxf) e13182. doi: 10.1111/apha.13182. | LEAK OXPHOS ET | N | Isolated mitochondria | Rat | Skeletal muscle |
Tripodi 2018 Biochim Biophys Acta Mol Cell Res | 2018 | Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13. | OXPHOS LEAK | N S | Isolated mitochondria | Saccharomyces cerevisiae | |
Stein 2018 Cell Rep | 2018 | Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Heart Skeletal muscle |
Martinez-Palma 2018 Neurotherapeutics | 2018 | Martínez-Palma L, Miquel E, Lagos-Rodríguez V, Barbeito L, Cassina A, Cassina P (2018) Mitochondrial modulation by dichloroacetate reduces toxicity of aberrant glial cells and gliosis in the SOD1G93A rat model of amyotrophic lateral sclerosis. Neurotherapeutics 16:203-15. | LEAK ET | ROX | Intact cells | Rat | Nervous system |
Efimova 2018 Thesis | 2018 | Efimova I (2018) Structural composition and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | HEK |
Lund 2018 Acta Physiol (Oxf) | 2018 | Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, Støckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Perks 2018 Cell Rep | 2018 | Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42. | LEAK OXPHOS ET | N Gp S | Isolated mitochondria | Mouse | Heart |
Klepinin 2018 J Bioenerg Biomembr | 2018 | Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Heart Neuroblastoma |
Pardo 2018 FASEB J | 2018 | Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA (2018) Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue. FASEB J 33:2343-58. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Fat |
Gorgey 2018 Eur J Appl Physiol | 2018 | Gorgey AS, Witt O, O'Brien L, Cardozo C, Chen Q, Lesnefsky EJ, Graham ZA (2018) Mitochondrial health and muscle plasticity after spinal cord injury. Eur J Appl Physiol 119:315-31. | OXPHOS LEAK | N S CIV NS | Permeabilized tissue | Human | Skeletal muscle |
Logan 2018 Mol Metab | 2018 | Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55. | LEAK OXPHOS | N S NS | Isolated mitochondria | Mouse | Nervous system |
JanssenDuijghuijsen 2018 Thesis | 2018 | JanssenDuijghuijsen LM (2018) Good, Bad, or Risky? Intestinal permeability to protein: Human and in vitro studies. Doctoral Thesis p154. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Cunatova 2018 Thesis | 2018 | Čunátová K (2018) The role of tissue specific isoforms of subunit 4 in assembly and function of cytochrome c oxidase. PhD Thesis p107. | LEAK ROUTINE ET | CIV ROX | Intact cells | Human | HEK |
Merz 2018 Intensive Care Med Exp | 2018 | Merz T, Wepler M, Nußbaum B, Vogt J, Calzia E, Wang R, Szabo C, Radermacher P, McCook O (2018) Cystathionine-γ-lyase expression is associated with mitochondrial respiration during sepsis-induced acute kidney injury in swine with atherosclerosis. Intensive Care Med Exp 6:43. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Pig | Kidney |
Brunetta 2018 Exp Physiol | 2018 | Brunetta HS, de Paula GC, de Oliveira J, Martins EL, Dos Santos GJ, Filho AG, Rafacho A, de Bem AF, Nunes EA (2018) Decrement in resting and insulin-stimulated soleus muscle mitochondrial respiration is an early event in diet-induced obesity in mice. Exp Physiol 104:306-21. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Ferri 2018 Eur J Appl Physiol | 2018 | Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ (2018) Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia. Eur J Appl Physiol 118:1641-52. | LEAK OXPHOS | N | Permeabilized tissue | Rat | Heart Skeletal muscle |
Monaco 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204. | LEAK OXPHOS | N NS | Permeabilized tissue Isolated mitochondria | Rat | Heart |
Szelechowski 2018 Sci Rep | 2018 | Szelechowski M, Amoedo N, Obre E, Léger C, Allard L, Bonneu M, Claverol S, Lacombe D, Oliet S, Chevallier S, Le Masson G, Rossignol R (2018) Metabolic reprogramming in amyotrophic lateral sclerosis. Sci Rep 8:3953. | LEAK ROUTINE ET | F ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
MitoFit Open Seminar 2017-07-14 | 2017-07-14 |
Innsbruck AT, 2017 Jul 14. MitoFit Open Seminar on immune cell bioenergetics. Investigating the role of mitochondria in healthy and psychopathological aging. | LEAK ROUTINE ET | Intact cells | Human | Blood cells | |
Braz-Mota 2017 Thesis | 2017 | Braz Mota S (2017) Estudo comparativo da toxicidade e dos mecanismos de ação tóxica de nanopartículas de cobre e cobre em duas espécies de peixes da Amazônia: Apistogramma agassizii e Paracheirodon axelrodi. Dissertation p.78. | LEAK OXPHOS ET | N NS ROX | Homogenate | Fishes | Lung;gill |
JanssenDuijghuijsen 2017 Front Physiol | 2017 | JanssenDuijghuijsen LM, Grefte S, de Boer VCJ, Zeper L, van Dartel DAM, van der Stelt I, Bekkenkamp-Grovenstein M, van Norren K, Wichers HJ, Keijer J (2017) Mitochondrial ATP depletion disrupts Caco-2 monolayer integrity and internalizes Claudin 7. Front Physiol 8:794. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Makrecka-Kuka 2017 Toxicol Lett | 2017 | Makrecka-Kuka M, Volska K, Antone U, Vilskersts R, Grinberga S, Bandere D, Liepinsh E, Dambrova M (2017) Trimethylamine N-oxide impairs pyruvate and fatty acid oxidation in cardiac mitochondria. Toxicol Lett 267:32-8. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Newsom 2017 Am J Physiol Endocrinol Metab | 2017 | Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Da Silva 2017 Neurotox Res | 2017 | Da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M (2017) α-Ketoadipic acid and α-aminoadipic acid cause disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90. | LEAK OXPHOS ET | N | Isolated mitochondria Homogenate | Rat | Nervous system |
Wolff 2017 Thesis | 2017 | Wolff C (2017) Impact of lipid metabolism on skeletal muscle mitochondrial function in type 2 diabetes mellitus patients. Dissertation p68. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Horse Human | Skeletal muscle |
Rodrigues-Silva 2017 J Neurooncol | 2017 | Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. 10.1007/s11060-017-2482-0 | LEAK ROUTINE OXPHOS ET | N ROX | Permeabilized cells Isolated mitochondria Intact cells | Rat | Nervous system |
Perks 2017 Sci Adv | 2017 | Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A (2017) Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Heart Liver |
Koning 2017 J Cereb Blood Flow Metab | 2017 | Koning G, Leverin AL, Nair S, Schwendimann L, Ek J, Carlsson Y, Gressens P, Thornton C, Wang X, Mallard C, Hagberg H (2017) Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection. J Cereb Blood Flow Metab 39:1038-55. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Rat | |
Schatton 2017 J Cell Biol | 2017 | Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017) CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-93. | LEAK OXPHOS ET | N NS | Intact cells Isolated mitochondria | Mouse | Liver |
Buck 2017 PLOS ONE | 2017 | Buck E, Zügel M, Schumann U, Merz T, Gumpp AM, Witting A, Steinacker JM, Landwehrmeyer GB, Weydt P, Calzia E, Lindenberg KS (2017) High-resolution respirometry of fine-needle muscle biopsies in pre-manifest Huntington's disease expansion mutation carriers shows normal mitochondrial respiratory function. PLOS ONE 12:e0175248. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Human Mouse | Heart Skeletal muscle Nervous system Liver |
Khalifa 2017 Physiol Rep | 2017 | Khalifa AR, Abdel-Rahman EA, Mahmoud AM, Ali MH, Noureldin M, Saber SH, Mohsen M, Ali SS (2017) Sex-specific differences in mitochondria biogenesis, morphology, respiratory function, and ROS homeostasis in young mouse heart and brain. Physiol Rep 5. pii: e13125. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Heart Nervous system |
Du 2017 Evolution | 2017 | Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52. | LEAK OXPHOS ET | N NS ROX S | Isolated mitochondria | Fishes | Liver |
Warren 2017 J Nutr Metab | 2017 | Warren JL, Gower BA, Hunter GR, Windham ST, Moellering DR, Fisher G (2017) Associations of mitochondrial fatty acid oxidation with body fat in premenopausal women. J Nutr Metab 2017:7832057. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
Jang 2017 Clin Toxicol (Phila) | 2017 | Jang DH, Kelly M, Hardy K, Lambert DS, Shofer FS, Eckmann DM (2017) A preliminary study in the alterations of mitochondrial respiration in patients with carbon monoxide poisoning measured in blood cells. Clin Toxicol (Phila) 55:579-84. | LEAK ROUTINE OXPHOS ET | F S CIV NS ROX | Intact cells | Blood cells | |
Xu 2017 Diabetes | 2017 | Xu D, Xu S, Kyaw AMM, Lim YC, Chia SY, Chee Siang DT, Alvarez-Dominguez JR, Chen P, Leow MK, Sun L (2017) RNA binding protein Ybx2 regulates RNA stability during cold-induced brown fat activation. Diabetes 66:2987-3000. | LEAK OXPHOS ET | N ROX | Mouse | Skeletal muscle | |
Dolezal 2017 J Biol Chem | 2017 | Dolezal JM, Wang H, Kulkarni S, Jackson L, Lu J, Ranganathan S, Goetzman ES, Bharathi SS, Beezhold K, Byersdorfer CA, Prochownik EV (2017) Sequential adaptive changes in a c-Myc-driven model of hepatocellular carcinoma. J Biol Chem 292:10068-86. | LEAK OXPHOS | N S NS | Intact cells | Mouse | Liver |
Komlodi 2017 Neuropharmacology | 2017 | Komlódi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98. | LEAK OXPHOS ET | N S | Isolated mitochondria | Guinea pig | Nervous system |
Fink 2017 Am J Physiol Cell Physiol | 2017 | Fink BD, Bai F, Yu L, Sivitz WI (2017) Regulation of ATP production: dependence on calcium concentration and respiratory state. Am J Physiol Cell Physiol 313:C146-53. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Skeletal muscle |
Thomsen 2017 Neurobiol Aging | 2017 | Thomsen K, Yokota T, Hasan-Olive MM, Sherazi N, Fakouri NB, Desler C, Regnell CE, Larsen S, Rasmussen LJ, Dela F, Bergersen LH, Lauritzen M (2017) Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus. Neurobiol Aging 61:215-24. | LEAK OXPHOS | N NS ROX | Mouse | Nervous system | |
Darrell 2017 US Patent | 2017 | Neufer PD, Anderson EJ, Szeto HH (2017) Methods for preventing or treating insulin resistance. US Patent US20170100450 A1. | LEAK OXPHOS | F N S ROX | Permeabilized tissue | Human Rat | Skeletal muscle |
Gusdon 2017 Exp Gerontol | 2017 | Gusdon AM, Callio J, Distefano G, O'Doherty RM, Goodpaster BH, Coen PM, Chu CT (2017) Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice. Exp Gerontol 90:1-13. | LEAK OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
Wen 2017 Antioxid Redox Signal | 2017 | Wen JJ, Porter C, Garg NJ. (2017) Inhibition of NFE2L2-Antioxidant Response Element Pathway by Mitochondrial Reactive Oxygen Species Contributes to Development of Cardiomyopathy and Left Ventricular Dysfunction in Chagas Disease. Antioxid Redox Signal. 27(9):550-566. | LEAK OXPHOS ET | Permeabilized tissue | Mouse | Heart | |
Lalia 2017 Aging (Albany NY) | 2017 | Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129. | OXPHOS LEAK ET | F N NS ROX S | Isolated mitochondria | Human | Skeletal muscle |
Asiri 2017 Thesis | 2017 | Asiri A (2017) Effects of asiatic acid on neurite outgrowth in Neuro-2a cells. Master's Thesis p42. | LEAK ROUTINE ET | Intact cells | Mouse | Nervous system | |
Dixit 2017 Free Radic Biol Med | 2017 | Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Heart |
Sidlauskas 2017 Neurosci Lett | 2017 | Sidlauskas K, Sidlauskiene R, Li N, Liobikas J (2017) 5-Hydroxy-1,4-naphthalenedione exerts anticancer effects on glioma cells through interaction with the mitochondrial electron transport chain. Neurosci Lett 639:207-14. | OXPHOS LEAK ROUTINE ET | N S | Intact cells Permeabilized cells | Rat | Nervous system Other cell lines |
Mathers 2017 J Comp Physiol B | 2017 | Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34. | LEAK OXPHOS | N S CIV ROX DQ | Intact cells Isolated mitochondria | Other mammals | Liver |
Krycer 2017 Biochem Biophys Res Commun | 2017 | Krycer JR, Fisher-Wellman KH, Fazakerley DJ, Muoio DM, James DE (2017) Bicarbonate alters cellular responses in respiration assays. Biochem Biophys Res Commun 489:399-403. | LEAK OXPHOS | N NS | Permeabilized cells Intact cells | Mouse | Liver Fat |
Thomas 2017 Thesis | 2017 | Thomas NO (2017) Age-related decrease in resilience against acute redox cycling agents: critical role of declining GSH-dependent detoxification capacity. Dissertation p141. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Rat | Liver |
De Carvalho 2017 Toxicol Research | 2017 | de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 . | LEAK OXPHOS ET | F N NS ROX S | Isolated mitochondria | Drosophila | |
Crouch 2017 PLOS ONE | 2017 | Crouch ML, Knowels G, Stuppard R, Ericson NG, Bielas JH, Marcinek DJ, Syrjala KL (2017) Cyclophosphamide leads to persistent deficits in physical performance and in vivo mitochondria function in a mouse model of chemotherapy late effects. PLOS ONE 12:e0181086. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Fourcade 2017 Aging Cell | 2017 | Fourcade S, Morató L, Parameswaran J, Ruiz M, Ruiz-Cortés T, Jové M, Naudí A, Martínez-Redondo P, Dierssen M, Ferrer I, Villarroya F, Pamplona R, Vaquero A, Portero-Otín M, Pujol A (2017) Loss of SIRT2 leads to axonal degeneration and locomotor disability associated with redox and energy imbalance. Aging Cell 16:1404-13. | LEAK OXPHOS | N S NS ROX | Mouse | ||
Cecatto 2017 Neurochem Int | 2017 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45. | LEAK OXPHOS ET | N | Isolated mitochondria | Rat | Nervous system Liver |
Correa 2017 Crit Care | 2017 | Corrêa TD, Pereira AJ, Brandt S, Vuda M, Djafarzadeh S, Takala J, Jakob SM (2017) Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Crit Care 21:105. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Pig | Nervous system |
Trewin 2017 PLOS ONE | 2017 | Trewin AJ, Levinger I, Parker L, Shaw CS, Serpiello FR, Anderson MJ, McConell GK, Hare DL, Stepto NK (2017) Acute exercise alters skeletal muscle mitochondrial respiration and H2O2 emission in response to hyperinsulinemic-euglycemic clamp in middle-aged obese men. PLOS ONE 12:e0188421. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Uzhachenko 2017 Aging (Albany NY) | 2017 | Uzhachenko R, Boyd K, Olivares-Villagomez D, Zhu Y, Goodwin JS, Rana T, Shanker A, Tan WJ, Bondar T, Medzhitov R, Ivanova AV (2017) Mitochondrial protein Fus1/Tusc2 in premature aging and age-related pathologies: critical roles of calcium and energy homeostasis. Aging (Albany NY) 9:627-49. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Kidney Endothelial;epithelial;mesothelial cell Fibroblast |
Holland 2017 Placenta | 2017 | Holland OJ, Hickey AJR, Alvsaker A, Moran S, Hedges C, Chamley LW, Perkins AV (2017) Changes in mitochondrial respiration in the human placenta over gestation. Placenta 57:102-12. | LEAK ROUTINE OXPHOS | F N CIV NS ROX | Permeabilized cells Intact cells | Genital | |
Scheede-Bergdahl 2017 Can J Physiol Pharmacol | 2017 | Scheede-Bergdahl C, Bergdahl A (2017) Adaptation of mitochondrial expression and ATP production in dedifferentiating vascular smooth muscle cells. Can J Physiol Pharmacol 95:1473-9. | LEAK OXPHOS | F N CIV NS ROX | Permeabilized tissue | Mouse | Endothelial;epithelial;mesothelial cell |
Canevarolo 2017 Thesis | 2017 | Canevarolo RR (2017) Resistência ao metotrexato está diretamente associada à concentração de glutationa em linhagens de leucemia linfoide aguda. Dissertation p159. | LEAK ROUTINE ET | Intact cells | Human | Macrophage-derived | |
Zholobenko 2017 PLOS ONE | 2017 | Zholobenko AV, Mouithys-Mickalad A, Dostal Z, Serteyn D, Modriansky M (2017) On the causes and consequences of the uncoupler-like effects of quercetin and dehydrosilybin in H9c2 cells. PLOS ONE 12:e0185691. | LEAK OXPHOS ET ROUTINE | F N S NS ROX | Permeabilized cells Intact cells | Rat | Heart |
Wetzel 2017 Thesis | 2017 | Wetzel MD (2017) Mechanism of metformin action in dermal fibroblasts. PhD Thesis 125. | LEAK OXPHOS | F N NS ROX | Intact cells | Human | Fibroblast |
Mottahedin 2017 J Cereb Blood Flow Metab | 2017 | Mottahedin A, Svedin P, Nair S, Mohn CJ, Wang X, Hagberg H, Ek J, Mallard C (2017) Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain. J Cereb Blood Flow Metab 37:1192-8. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Nervous system |
Sobotka 2017 Thesis | 2017 | Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127. | LEAK OXPHOS ET | F N NS | Homogenate Isolated mitochondria Intact cells | Mouse Rat | Liver |
Hals 2017 Physiol Rep | 2017 | Hals I, Ohki T, Singh R, Ma Z, Björklund A, Balasuriya C, Scholz H, Grill V (2017) Hyperoxia reduces insulin release and induces mitochondrial dysfunction with possible implications for hyperoxic treatment of neonates. Physiol Rep 5. pii: e13447. | LEAK OXPHOS ET | N | Permeabilized cells | Human Mouse | Islet cell;pancreas;thymus |
De Souza 2017 Thesis | 2017 | de Souza LF (2017) Modulação redox de peroxirredoxinas e a participação dos sistemas da GSH e da Trx na proteção/função celular. Tese (doutorado) p103. | LEAK ROUTINE ET | Intact cells | Human | Other cell lines | |
Miller 2017 PLOS ONE | 2017 | Miller B, Hamilton K, Boushel R, Williamson K, Laner V, Gnaiger E, Davis M (2017) Mitochondrial respiration in highly aerobic canines in the non-raced state and after a 1600-km sled dog race. PLOS ONE 12:e0174874. | OXPHOS ET LEAK | F N S NS ROX | Permeabilized tissue | Dog | Skeletal muscle |
Schmidt 2017 J Vasc Surg | 2017 | Schmidt CA, Ryan TE, Lin CT, Inigo MM, Green TD, Brault JJ, Spangenburg EE, McClung JM (2017) Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia. J Vasc Surg 65:1504-1514. | OXPHOS ET LEAK | N S CIV NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Napa 2017 Int J Dent | 2017 | Napa K, Baeder AC, Witt JE, Rayburn ST, Miller MG, Dallon BW, Gibbs JL, Wilcox SH, Winden DR, Smith JH, Reynolds PR, Bikman BT (2017) LPS from P. gingivalis negatively alters gingival cell mitochondrial bioenergetics. Int J Dent 2017:2697210. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell |
Ounpuu 2017 Biochim Biophys Acta | 2017 | Ounpuu L, Klepinin A, Pook M, Teino I, Peet N, Paju K, Tepp K, Chekulayev V, Shevchuk I, Koks S, Maimets T, Kaambre T (2017) 2102Ep embryonal carcinoma cells have compromised respiration and shifted bioenergetic profile distinct from H9 human embryonic stem cells. Biochim Biophys Acta 1861:2146-54. | LEAK ROUTINE OXPHOS ET | N S NS ROX CIV | Permeabilized cells Intact cells | Human | Stem cells |
Yu 2017 Free Radic Biol Med | 2017 | Yu Y, Wang L, Delguste F, Durand A, Guilbaud A, Rousselin C, Schmidt AM, Tessier F, Boulanger E, Neviere R (2017) Advanced glycation end products receptor RAGE controls myocardial dysfunction and oxidative stress in high-fat fed mice by sustaining mitochondrial dynamics and autophagy-lysosome pathway. Free Radic Biol Med 112:397-410. | LEAK OXPHOS | F N CIV ROX | Permeabilized tissue | Mouse | Heart |
Comelli 2017 J Bioenerg Biomembr | 2017 | Comelli M, Pretis I, Buso A, Mavelli I (2017) Mitochondrial energy metabolism and signalling in human glioblastoma cell lines with different PTEN gene status. J Bioenerg Biomembr 50:33-52. | LEAK ROUTINE OXPHOS ET | N Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Nervous system |
Busanello 2017 Front Pharmacol | 2017 | Busanello ENB, Marques AC, Lander N, de Oliveira DN, Catharino RR, Oliveira HCF, Vercesi AE (2017) Pravastatin chronic treatment sensitizes hypercholesterolemic mice muscle to mitochondrial permeability transition: protection by creatine or coenzyme Q10. Front Pharmacol 8:185. | LEAK OXPHOS ET | N | Permeabilized tissue | Mouse | Skeletal muscle |
Nabeebaccus 2017 JCI Insight | 2017 | Nabeebaccus AA, Zoccarato A, Hafstad AD, Santos CX, Aasum E, Brewer AC, Zhang M, Beretta M, Yin X, West JA, Schröder K, Griffin JL, Eykyn TR, Abel ED, Mayr M, Shah AM (2017) Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. JCI Insight 2:96184. | LEAK ET | F N | Isolated mitochondria | Mouse | Heart |
Vienne 2017 Anal Biochem | 2017 | Vienne JC, Cimetta C, Dubois M, Duburcq T, Favory R, Dessein AF, Fontaine M, Joncquel-Chevalier Curt M, Cuisset JM, Douillard C, Mention-Mulliez K, Dobbelaere D, Vamecq J (2017) A fast method for high resolution oxymetry study of skeletal muscle mitochondrial respiratory chain complexes. Anal Biochem 528:57-62. | LEAK OXPHOS ET | N CIV ROX S | Homogenate Permeabilized tissue | Pig | Skeletal muscle |
Bowen 2017 J Am Heart Assoc | 2017 | Bowen TS, Brauer D, Rolim NPL, Bækkerud FH, Kricke A, Ormbostad Berre AM, Fischer T, Linke A, da Silva GJ, Wisloff U, Adams V (2017) Exercise training reveals inflexibility of the diaphragm in an animal model of patients with obesity-driven heart failure with a preserved ejection fraction. J Am Heart Assoc 6. pii: e006416. | LEAK OXPHOS | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Fisar 2017 Indian J Biochem Biophys | 2017 | Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Pig | Nervous system |
Profilo 2017 Biochim Biophys Acta | 2017 | Profilo E, Peña-Altamira LE, Corricelli M, Castegna A, Danese A, Agrimi G, Petralla S, Giannuzzi G, Porcelli V, Sbano L, Viscomi C, Massenzio F, Palmieri EM, Giorgi C, Fiermonte G, Virgili M, Palmieri L, Zeviani M, Pinton P, Monti B, Palmieri F, Lasorsa FM (2017) Down-regulation of the mitochondrial aspartate-glutamate carrier isoform 1 AGC1 inhibits proliferation and N-acetylaspartate synthesis in Neuro2A cells. Biochim Biophys Acta 1863:1422-35. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Nervous system Other cell lines Neuroblastoma |
Rezania 2017 Thromb Res | 2017 | Rezania S, Puskarich MA, Petrusca DN, Neto-Neves EM, Rondina MT, Kline JA (2017) Platelet hyperactivation, apoptosis and hypercoagulability in patients with acute pulmonary embolism. Thromb Res 155:106-15. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells Platelet |
Mahalingam 2017 J Physiol | 2017 | Mahalingam S, McClelland GB, Scott GR (2017) Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol 595:4785-801. | LEAK OXPHOS | N CIV NS | Permeabilized tissue Isolated mitochondria | Mouse | Skeletal muscle |
Sivertsson 2017 Am J Physiol Renal Physiol | 2017 | Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872. | LEAK OXPHOS | N | Isolated mitochondria | Rat | Kidney |
Horscroft 2017 Proc Natl Acad Sci U S A | 2017 | Horscroft JA, Kotwica AO, Laner V, West JA, Hennis PJ, Levett DZH, Howard DJ, Fernandez BO, Burgess SL, Ament Z, Gilbert-Kawai ET, Vercueil A, Landis BD, Mitchell K, Mythen MG, Branco C, Johnson RS, Feelisch M, Montgomery HE, Griffin JL, Grocott MPW, Gnaiger E, Martin DS, Murray AJ (2017) Metabolic basis to Sherpa altitude adaptation. Proc Natl Acad Sci U S A 114:6382–7. https://doi.org/10.1073/pnas.1700527114 | LEAK OXPHOS ET | F N S NS Other combinations | Permeabilized tissue | Human | Skeletal muscle |
Li 2017 Oxid Med Cell Longev | 2017 | Li CJ, Chen PK, Sun LY, Pang CY (2017) Enhancement of mitochondrial transfer by antioxidants in human mesenchymal stem cells. Oxid Med Cell Longev 2017:8510805. | ET LEAK ROUTINE | ROX | Intact cells | Human | Fat |
Wu 2017 Sci Rep | 2017 | Wu LH, Chang SC, Fu TC, Huang CH, Wang JS (2017) High-intensity interval training improves mitochondrial function and suppresses thrombin generation in platelets undergoing hypoxic stress. Sci Rep 7:4191. | LEAK OXPHOS ET ROUTINE | N NS ROX CIV | Permeabilized cells Intact cells | Human | Blood cells Platelet |
Elmer 2017 US Patent | 2017 | Elmer E, Hansson MJ, Ehinger JK, Piel S, Moss S (2017) Succinate prodrugs for use in the treatment of lactic acidosis or drug-induced side-effects due to complex I-related impairment of mitochondrial oxidative phosphorylation. US Patent US20170100359 A1. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Heart Blood cells Fibroblast Macrophage-derived Platelet |
Phillips 2017 Cancer Res | 2017 | Phillips CM, Zatarain JR, Nicholls ME, Porter C, Widen SG, Thanki K, Johnson P, Jawad MU, Moyer MP, Randall JW, Hellmich JL, Maskey M, Qiu S, Wood TG, Druzhyna N, Szczesny B, Módis K1, Szabo C, Chao C, Hellmich MR. (2017) Upregulation of Cystathionine-β-Synthase in Colonic Epithelia Reprograms Metabolism and Promotes Carcinogenesis.. Cancer Res. 77(21):5741-5754. | LEAK ROUTINE ET | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Anderson 2017 Cell Metab | 2017 | Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55. | OXPHOS LEAK | F N NS Other combinations | Isolated mitochondria | Mouse | Heart Liver |
Nogueira 2017 Free Radic Biol Med | 2017 | Nogueira NP, Saraiva FMS, Oliveira MP, Mendonca APM, Inacio JDF, Almeida-Amaral EE, Menna-Barreto RF, Laranja GAT, Lopes Torres EJ, Oliveira MF, Paes MC (2017) Heme modulates Trypanosoma cruzi bioenergetics inducing mitochondrial ROS production. Free Radic Biol Med 108:183-91. | LEAK ROUTINE OXPHOS ET | S | Intact organism Permeabilized cells | Protists | |
Alves 2017 Free Radic Biol Med | 2017 | Alves de Souza CE, Alves de Souza HM, Stipp MC, Corso CR, Galindo CM, Cardoso CR, Dittrich RL, de Souza Ramos EA, Klassen G, Carlos RM, Correia Cadena SMS, Acco A (2017) Ruthenium complex exerts antineoplastic effects that are mediated by oxidative stress without inducing toxicity in Walker-256 tumor-bearing rats. Free Radic Biol Med 110:228-39. | LEAK ROUTINE | ROX | Rat | ||
Porplycia 2017 Am J Physiol Regul Integr Comp Physiol | 2017 | Porplycia D, Lau GY, McDonald J, Chen Z, Richards JG, Moyes CD (2017) Subfunctionalization of COX4 paralogs in fish. Am J Physiol Regul Integr Comp Physiol 312:R671-R680. | LEAK | CIV ROX | Isolated mitochondria | Fishes | Skeletal muscle |
Campos 2017 Autophagy | 2017 | Campos JC, Queliconi BB, Bozi LHM, Bechara LRG, Dourado PMM, Andres AM, Jannig PR, Gomes KMS, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB (2017) Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy 13:1304-317. | LEAK OXPHOS ET | NS | Isolated mitochondria | Rat | Heart |
White 2017 Sci Rep | 2017 | White SH, Warren LK, Li C, Wohlgemuth SE (2017) Submaximal exercise training improves mitochondrial efficiency in the gluteus medius but not in the triceps brachii of young equine athletes. Sci Rep 7:14389. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Warren 2017 Metabolism | 2017 | Warren JL, Bulur S, Ovalle F, Windham ST, Gower BA, Fisher G (2017) Effects of acute hyperinsulinemia on skeletal muscle mitochondrial function, reactive oxygen species production, and metabolism in premenopausal women. Metabolism 77:1-12. | LEAK OXPHOS | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Teplova 2017 Toxicol Lett | 2017 | Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17. | OXPHOS LEAK | N S CIV | Isolated mitochondria | Rat | Liver |
Duicu 2017 Can J Physiol Pharmacol | 2017 | Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Heart |
Schreiber 2017 Cell Metab | 2017 | Schreiber R, Diwoky C, Schoiswohl G, Feiler U, Wongsiriroj N, Abdellatif M, Kolb D, Hoeks J, Kershaw EE, Sedej S, Schrauwen P, Haemmerle G, Zechner R (2017) Cold-induced thermogenesis depends on ATGL-mediated lipolysis in cardiac muscle, but not brown adipose tissue. Cell Metab 26:753-63. | LEAK | N Gp | Homogenate | Mouse | Fat |
Uppala 2017 Biochem Biophys Res Commun | 2017 | Uppala R, Dudiak B, Beck ME, Bharathi SS, Zhang Y, Stolz DB, Goetzman ES (2017) Aspirin increases mitochondrial fatty acid oxidation. Biochem Biophys Res Commun 482:346-51. | OXPHOS LEAK ET | N NS | Permeabilized cells | Human Mouse | HEK Fibroblast |
Honrath 2017 Cell Death Differ | 2017 | Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM (2017) SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. Cell Death Differ 24:761-73. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Nervous system Other cell lines |
Kenny 2017 Diabetologia | 2017 | Kenny HC, Rudwill F, Breen L, Salanova M, Blottner D, Heise T, Heer M, Blanc S, O'Gorman DJ (2017) Bed rest and resistive vibration exercise unveil novel links between skeletal muscle mitochondrial function and insulin resistance. Diabetologia 60:1491-501. | LEAK OXPHOS ET | N S CIV NS F | Permeabilized tissue | Human | Skeletal muscle |
Michalak 2017 Oxid Med Cell Longev | 2017 | Michalak S, Florczak-Wyspiańska J, Rybacka-Mossakowska J, Ambrosius W, Osztynowicz K, Baszczuk A, Kozubski W, Wysocka E (2017) Mitochondrial respiration in intact peripheral blood mononuclear cells and sirtuin 3 activity in patients with movement disorders. Oxid Med Cell Longev 2017:9703574. | LEAK ROUTINE ET | ROX | Intact cells | Blood cells | |
Dallon 2017 Biochem J | 2017 | Dallon BW, Parker BA, Hodson AE, Tippetts TS, Harrison ME, Appiah MMA, Witt JE, Gibbs JL, Gray HM, Sant TM, Bikman BT (2017) Insulin selectively reduces mitochondrial uncoupling in brown adipose tissue in mice. Biochem J 475:561-9. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Fat |
Boutant 2017 EMBO J | 2017 | Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58. | ROUTINE LEAK OXPHOS ET | ROX N S NS | Intact cells Homogenate Isolated mitochondria | Mouse | Fat Fibroblast |
Merz 2017 Intensive Care Med Exp | 2017 | Merz T, Vogt JA, Wachter U, Calzia E, Szabo C, Wang R, Radermacher P, McCook O (2017) Impact of hyperglycemia on cystathionine-γ-lyase expression during resuscitated murine septic shock. Intensive Care Med Exp 5:30. | LEAK OXPHOS ET | F N S NS ROX | Homogenate | Mouse | Liver |
Cardinale 2017 Front Physiol | 2017 | Cardinale DA, Lilja M, Mandić M, Gustafsson T, Larsen FJ, Lundberg TR (2017) Resistance training with co-ingestion of anti-inflammatory drugs attenuates mitochondrial function. Front Physiol 8:1074. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Lau 2017 Mol Biol Evol | 2017 | Lau GY, Mandic M, Richards JG (2017) Evolution of cytochrome c oxidase in hypoxia tolerant Sculpins (Cottidae, Actinopterygii). Mol Biol Evol 34:2153-62. | LEAK OXPHOS ET | CIV NS ROX | Isolated mitochondria | Fishes | Nervous system |
Xu 2017 J Hum Genet | 2017 | Xu B, Li X, Du M, Zhou C, Fang H, Lyu J, Yang Y (2017) Novel mutation of ND4 gene identified by targeted next-generation sequencing in patient with Leigh syndrome. J Hum Genet 62:291-7. | LEAK ROUTINE | Intact cells | Human | Blood cells Platelet | |
Chin 2017 US Patent | 2017 | Chin MT, Chien WM, Dinca A (2017) Methods for treating and preventing cardiomyopathy. US Patent WO2016094791A1. | LEAK OXPHOS ET | N CIV ROX | Homogenate | Mouse | Heart |
Haegler 2017 PLOS ONE | 2017 | Haegler P, Grünig D, Berger B, Terracciano L, Krähenbühl S, Bouitbir J (2017) Hepatic effects of pharmacological doses of hydroxy-cobalamin[c-lactam] in mice. PLOS ONE 12:e0171026. | LEAK OXPHOS ET | N S CIV ROX DQ | Homogenate | Mouse | Liver |
Rekuviene 2017 Data Brief | 2017 | Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Data on effects of rotenone on calcium retention capacity, respiration and activities of respiratory chain complexes I and II in isolated rat brain mitochondria. Data Brief 13:707-12. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Nervous system |
Dent 2017 Mol Metab | 2017 | Dent JR, Martins VF, Svensson K, LaBarge SA, Schlenk NC, Esparza MC, Buckner EH, Meyer GA, Hamilton DL, Schenk S, Philp A (2017) Muscle-specific knockout of general control of amino acid synthesis 5 (GCN5) does not enhance basal or endurance exercise-induced mitochondrial adaptation. Mol Metab 6:1574-84. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Victor 2017 Thesis | 2017 | Victor L (2017) Investigating the possible cytoprotective effects of melatonin isomer against simulated ischemic injury. Master's Thesis 76. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells | Rat | Fibroblast |
Zhang 2017 J Am Heart Assoc | 2017 | Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945. | LEAK OXPHOS | N | Isolated mitochondria | Rabbit | Heart |
Lau 2017 Dissertation | 2017 | Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Fishes | Nervous system |
Cunha 2017 Int J Biol Macromol | 2017 | Cunha de Padua MM, Suter Correia Cadena SM, de Oliveira Petkowicz CL, Martinez GR, Rodrigues Noleto G (2017) Galactomannan from Schizolobium amazonicum seed and its sulfated derivatives impair metabolism in HepG2 cells. Int J Biol Macromol 101:64-473. | LEAK ROUTINE ET | ROX | Intact cells | Human | Liver |
Vigueira 2017 Exp Physiol | 2017 | Vigueira PA, McCommis KS, Hodges WT, Schweitzer GG, Cole SL, Oonthonpan L, Taylor EB, McDonald WG, Kletzien RF, Colca JR, Finck BN (2017) The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol 102:985-99. | OXPHOS LEAK | N | Permeabilized cells | Human | Kidney HEK |
Park 2017 Metab Brain Dis | 2017 | Park HS, Cho HS, Kim TW (2017) Physical exercise promotes memory capability by enhancing hippocampal mitochondrial functions and inhibiting apoptosis in obesity-induced insulin resistance by high fat diet. Metab Brain Dis 33:283-92. | OXPHOS LEAK | N NS | Permeabilized tissue | Mouse | Nervous system |
De Moura 2017 Neurotox Res | 2017 | de Moura Alvorcem L, da Rosa MS, Glänzel NM, Parmeggiani B, Grings M, Schmitz F, Wyse ATS, Wajner M, Leipnitz G (2017) Disruption of energy transfer and redox status by sulfite in hippocampus, striatum, and cerebellum of developing rats. Neurotox Res 32:264-75. | LEAK OXPHOS ET | N S NS | Homogenate | Rat | Nervous system |
Mueller 2017 Orphanet J Rare Dis | 2017 | Mueller SM, Gehrig SM, Petersen JA, Frese S, Mihaylova V, Ligon-Auer M, Khmara N, Nuoffer JM, Schaller A, Lundby C, Toigo M, Jung HH (2017) Effects of endurance training on skeletal muscle mitochondrial function in Huntington disease patients. Orphanet J Rare Dis 12:184. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Calcutt 2017 J Clin Invest | 2017 | Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22. | LEAK OXPHOS ET | N CIV ROX | Isolated mitochondria | Rat | Nervous system |
Kyhl 2017 Peptides | 2017 | Kyhl K, Lønborg J, Hartmann B, Kissow H, Poulsen SS, Ali HE, Kjær A, Dela F, Engstrøm T, Treiman M (2017) Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction. Peptides 93:1-12. | OXPHOS LEAK | F N S NS ROX | Permeabilized tissue | Rat | Heart |
Min 2017 Skelet Muscle | 2017 | Min K, Lawan A, Bennett AM (2017) Loss of MKP-5 promotes myofiber survival by activating STAT3/Bcl-2 signaling during regenerative myogenesis. Skelet Muscle 7:21. | LEAK OXPHOS | N | Permeabilized tissue | Mouse | Skeletal muscle |
Davis 2017 Tissue Eng Part C Methods | 2017 | Davis BN, Santoso JW, Walker MJ, Cheng CS, Koves TR, Kraus WE, Truskey GA (2017) Human, tissue-engineered, skeletal muscle myobundles to measure oxygen uptake and assess mitochondrial toxicity. Tissue Eng Part C Methods 23:189-99. | LEAK ROUTINE ET | ROX | Intact cells | Human | Skeletal muscle |
Kake-Guena 2017 J Therm Biol | 2017 | Kake-Guena SA, Touisse K, Warren BE, Scott KY, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31. | LEAK OXPHOS | S Gp CIV NS ROX | Permeabilized tissue | Crustaceans | |
Djafarzadeh 2017b J Vis Exp | 2017 | Djafarzadeh S, Jakob SM (2017) Isolation of intact mitochondria from skeletal muscle by differential centrifugation for High-Resolution Respirometry measurements. J Vis Exp doi: 10.3791/55251. | LEAK OXPHOS | N S CIV NS | Isolated mitochondria | Skeletal muscle | |
Bansal 2017 Environ Health Perspect | 2017 | Bansal A, Rashid C, Xin F, Li C, Polyak E, Duemler A, van der Meer T, Stefaniak M, Wajid S, Doliba N, Bartolomei MS, Simmons RA (2017) Sex- and dose-specific effects of maternal bisphenol A exposure on pancreatic islets of first- and second-generation adult mice offspring. Environ Health Perspect 125:097022. | LEAK ROUTINE ET | ROX | Intact cells | Mouse | Islet cell;pancreas;thymus |
Derungs 2017 Mol Psychiatry | 2017 | Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Nervous system |
Kake 2017 J Therm Biol | 2017 | Kake Guena SA, Touisse K, Warren BE, Scott KY, Dufresne F, Blier PU, Lemieux H (2017) Temperature-related differences in mitochondrial function among clones of the cladoceran Daphnia pulex. J Therm Biol 69:23-31. | LEAK OXPHOS | N CIV NS S ROX | Permeabilized tissue | Crustaceans | |
Yeh 2017 Thesis | 2017 | Yeh A (2017) Modulation of mitochondrial function as an indicator for sublethal effects of contaminants of emerging concern. Dissertation p117. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized cells Permeabilized tissue | Human Fishes | Liver |
Mitroshina 2017 Mod Technol Med | 2017 | Mitroshina ЕV, Abogessimengane BZ, Urazov МD, Hamraoui I, Mishchenko ТА, Astrakhanova ТА, Shchelchkova NА, Lapshin RD, Shishkina ТV, Belousova II, Mukhina IV, Vedunova МV (2017) Adaptive role of glial cell line-derived neurotrophic factor in cerebral ischemia. Mod Technol Med 9:68-76. | OXPHOS LEAK | N S | Isolated mitochondria | Mouse | Nervous system |
Menezes-Filho 2017 Free Radic Biol Med | 2017 | Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ (2017) Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition. Free Radic Biol Med 110:219-27. | LEAK OXPHOS ET | Isolated mitochondria | Mouse | Liver | |
Beresewicz 2017 PLOS ONE | 2017 | Beręsewicz M, Boratyńska-Jasińska A, Charzewski Ł, Kawalec M, Kabzińska D, Kochański A, Krzyśko KA, Zabłocka B (2017) The effect of a novel c.820C>T (Arg274Trp) mutation in the mitofusin 2 gene on fibroblast metabolism and clinical manifestation in a patient. PLOS ONE 12:e0169999. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast | |
Volani 2017 Metallomics | 2017 | Volani C, Doerrier C, Demetz E, Haschka D, Paglia G, Lavdas AA, Gnaiger E, Weiss G (2017) Dietary iron loading negatively affects liver mitochondrial function. Metallomics 9:1634-44. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Liver |
Saintas 2017 PLOS ONE | 2017 | Saintas E, Abrahams L, Ahmad GT, Ajakaiye AM, AlHumaidi AS, Ashmore-Harris C, Clark I, Dura UK, Fixmer CN, Ike-Morris C, Mato Prado M, Mccullough D, Mishra S, Schöler KM, Timur H, Williamson MD, Alatsatianos M, Bahsoun B, Blackburn E, Hogwood CE, Lithgow PE, Rowe M, Yiangou L, Rothweiler F, Cinatl J Jr, Zehner R, Baines AJ, Garrett MD, Gourlay CW, Griffin DK, Gullick WJ, Hargreaves E, Howard MJ, Lloyd DR, Rossman JS, Smales CM, Tsaousis AD, von der Haar T, Wass MN, Michaelis M (2017) Acquired resistance to oxaliplatin is not directly associated with increased resistance to DNA damage in SK-N-ASrOXALI4000, a newly established oxaliplatin-resistant sub-line of the neuroblastoma cell line SK-N-AS. PLOS ONE 12:e0172140. | LEAK ROUTINE ET | Intact cells | Human | Nervous system Other cell lines | |
Chang 2017 J Biol Chem | 2017 | Chang JS, Ha K (2017) An unexpected role for the transcriptional coactivator isoform NT-PGC-1α in the regulation of mitochondrial respiration in brown adipocytes. J Biol Chem 292:9958-66. | LEAK ET ROUTINE | ROX | Intact cells | Mouse | Fat |
Bohanon 2017 Shock | 2017 | Bohanon FJ, Lopez ON, Herndon DN, Wang X, Bhattarai N, Ayadi AE, Prasai A, Jay JW, Rojas-Khalil Y, Toliver-Kinsky TE, Finnerty CC, Radhakrishnan RS, Porter C (2017) Burn trauma acutely increases the respiratory capacity and function of liver mitochondria. Shock 49:466-73. | LEAK OXPHOS ET | F N ROX | Intact cells | Mouse | Liver |
Cockova 2017 Thesis | 2017 | Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells Isolated mitochondria | Human | Nervous system |
Van Schaardenburgh 2017 J Vasc Surg | 2017 | Van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson E (2017) Calf raise exercise increases walking performance in patients with intermittent claudication. J Vasc Surg 65:1473-82. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Grassi 2017 J Appl Physiol (1985) | 2017 | Grassi B, Majerczak J, Bardi E, Buso A, Comelli M, Chlopicki S, Guzik M, Mavelli I, Nieckarz Z, Salvadego D, Tyrankiewicz U, Skórka T, Bottinelli R, Zoladz JA, Pellegrino MA (2017) Exercise training in Tgαq*44 mice during the progression of chronic heart failure: cardiac vs. peripheral (soleus muscle) impairments to oxidative metabolism. J Appl Physiol (1985) 123:326-36. | LEAK OXPHOS ET | N NS S | Permeabilized tissue | Mouse | Skeletal muscle |
Bal 2017 J Biol Chem | 2017 | Bal NC, Singh S, Reis FCG, Maurya SK, Pani S, Rowland LA, Periasamy M (2017) Both brown adipose tissue and skeletal muscle thermogenesis processes are activated during mild to severe cold adaptation in mice. J Biol Chem 292:16616-25. | LEAK OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle Fat |
Schoenfeld 2017 Neurochem Int | 2017 | Schönfeld P, Reiser G (2017) Brain energy metabolism spurns fatty acids as fuel due to their inherent mitotoxicity and potential capacity to unleash neurodegeneration. Neurochem Int 109:68-77. | OXPHOS LEAK | F N | Isolated mitochondria | Rat | Nervous system Liver |
Cardoso 2017 Biochim Biophys Acta | 2017 | Cardoso GMF, Pletsch JT, Parmeggiani B, Grings M, Glanzel NM, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2017) Bioenergetics dysfunction, mitochondrial permeability transition pore opening and lipid peroxidation induced by hydrogen sulfide as relevant pathomechanisms underlying the neurological dysfunction characteristic of ethylmalonic encephalopathy. Biochim Biophys Acta 1863:2192-2201. | LEAK OXPHOS ET | N S NS | Homogenate | Rat | Nervous system |
Dechandt 2017 J Bioenerg Biomembr | 2017 | Dechandt CRP, Zuccolotto-Dos-Reis FH, Teodoro BG, Fernandes AMAP, Eberlin MN, Kettelhut IC, Curti C, Alberici LC (2017) Triacsin C reduces lipid droplet formation and induces mitochondrial biogenesis in primary rat hepatocytes. J Bioenerg Biomembr 49:399-411. | LEAK ROUTINE ET | F N ROX | Permeabilized cells Intact cells | Rat | Liver |
Pamenter 2017 J Exp Biol | 2017 | Pamenter ME, Lau GY, Richards JG, Milsom WK (2017) Naked mole rat brain mitochondria electron transport system flux and H+ leak are reduced during acute hypoxia. J Exp Biol 221. | LEAK OXPHOS ET | N S CIV | Permeabilized cells | Other mammals | Nervous system |
Koit 2017 Oxid Med Cell Longev | 2017 | Koit A, Shevchuk I, Ounpuu L, Klepinin A, Chekulayev V, Timohhina N, Tepp K, Puurand M,Truu L, Heck K, Valvere V, Guzun R, Kaambre T (2017) Mitochondrial respiration in human colorectal and breast cancer clinical material is regulated differently. Oxid Med Cell Longev 2017:1372640. | OXPHOS LEAK | N S CIV ROX NS | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Theisen 2017 Am J Med Genet A | 2017 | Theisen BE, Rumyantseva A, Cohen JS, Alcaraz WA, Shinde DN, Tang S, Srivastava S, Pevsner J, Trifunovic A, Fatemi A (2017) Deficiency of WARS2, encoding mitochondrial tryptophanyl tRNA synthetase, causes severe infantile onset leukoencephalopathy. Am J Med Genet A 173:2505-10. | LEAK ROUTINE ET | ROX | Intact cells | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Kanaan 2017 Redox Biol | 2017 | Kanaan GN, Ichim B, Gharibeh L, Maharsy W, Patten DA, Xuan JY, Reunov A, Marshall P, Veinot J, Menzies K, Nemer M, Harper ME (2017) Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies. Redox Biol 14:509-21. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Cunha-de 2017 Thesis | 2017 | Cunha-de Padua MM (2017) Mecanismos citotóxicos da galactomanana de sementes de Schizolobium amazonicum e seus complexos com oxovanádio em células de hepatocarcinoma humano (HepG2) e efeito do silenciamento da enzima glucose-6-fosfato isomerase (GPI) na sobrevivência de células de adenocarcinoma de cólon humano (LS174T). Doctoral Thesis p160. | LEAK ROUTINE OXPHOS ET | N NS ROX | Intact cells Permeabilized cells | Human | Liver Other cell lines |
Linden 2016 Am J Physiol Gastrointest Liver Physiol | 2017 | Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95. | OXPHOS ET LEAK | N NS | Isolated mitochondria | Rat | Liver |
Yang 2017 Cell Death Dis | 2017 | Yang N, Weinfeld M, Lemieux H, Montpetit B, Goping IS (2017) Photo-activation of the delocalized lipophilic cation D112 potentiates cancer selective ROS production and apoptosis. Cell Death Dis 8:e2587. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Saccharomyces cerevisiae Human | Lymphocyte |
Testoni 2017 Cell Metab | 2017 | Testoni G, Duran J, García-Rocha M, Vilaplana F, Serrano AL, Sebastián D, López-Soldado I, Sullivan MA6, Slebe F, Vilaseca M, Muñoz-Cánoves P, Guinovart JJ (2017) Lack of glycogenin causes glycogen accumulation and muscle function impairment. Cell Metab 26:256-66. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Hartmann 2017 Crit Care Med | 2017 | Hartmann C, Loconte M, Antonucci E, Holzhauser M, Hölle T, Katzsch D, Merz T, McCook O, Wachter U, Vogt JA, Hoffmann A, Wepler M, Gröger M, Matejovic M, Calzia E, Georgieff M, Asfar P, Radermacher P, Nussbaum BL (2017) Effects of hyperoxia during resuscitation from hemorrhagic shock in swine with preexisting coronary artery disease. Crit Care Med 45:e1270-9. | LEAK OXPHOS ET | Homogenate | Pig | Heart Liver Kidney | |
Lee 2017 Am J Physiol Endocrinol Metab | 2017 | Lee S, Leone TC, Rogosa L, Rumsey J, Ayala J, Coen PM, Fitts RH, Vega RB, Kelly DP (2017) Skeletal muscle PGC-1β signaling is sufficient to drive an endurance exercise phenotype and to counteract components of detraining in mice. Am J Physiol Endocrinol Metab 312:E394-406. | LEAK OXPHOS | S | Permeabilized tissue | Mouse | Skeletal muscle |
Herledan 2017 Thesis | 2017 | Herledan G (2017) Le role de SRF au cours de l'atrophie du muscle squelettique adulte & dans les cellules satellites. Diploma Thesis p166. | LEAK OXPHOS ET | N CIV NS | Mouse | Skeletal muscle | |
Carraro 2017 Mol Cell Endocrinol | 2017 | Carraro RS, Souza GF, Solon C, Razolli DS, Chausse B, Barbizan R, Victorio SC, Velloso LA (2017) Hypothalamic mitochondrial abnormalities occur downstream of inflammation in diet-induced obesity. Mol Cell Endocrinol 460:238-45. | LEAK OXPHOS | N ROX | Permeabilized tissue | Mouse | Nervous system |
Joergensen 2017 Physiol Rep | 2017 | Jørgensen W, Rud KA, Mortensen OH, Frandsen L, Grunnet N, Quistorff B (2017) Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle. Physiol Rep 5. pii: e13207. | LEAK OXPHOS | F N NS | Isolated mitochondria | Rat | Skeletal muscle |
Van Schaardenburgh 2017 J Transl Med | 2017 | van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJR (2017) Exercise in claudicants increase or decrease walking ability and the response relates to mitochondrial function. J Transl Med 15:130. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Lou 2017 Physiol Rep | 2017 | Lou PH, Lucchinetti E, Scott KY, Huang Y, Gandhi M, Hersberger M, Clanachan AS, Lemieux H, Zaugg M (2017) Alterations in fatty acid metabolism and sirtuin signaling characterize early type-2 diabetic hearts of fructose-fed rats. Physiol Rep 5 pii: e13388. | LEAK OXPHOS | F N CIV NS | Rat | Heart | |
Qi 2017 Ann Allergy Asthma Immunol | 2017 | Qi S, Cindy Barnig C, Charles AL, Poirot A, Meyer A, Clere-Jehl R, de Blay F, Geny B (2017) Nasal allergen challenge in allergic rhinitis induces mitochondrial dysfunction of peripheral blood mononuclear cells. Ann Allergy Asthma Immunol 118:367-9. | OXPHOS LEAK | N S CIV | Permeabilized cells | Human | Blood cells Lymphocyte |
Ruiz 2017 Brain Pathol | 2017 | Ruiz M, Bégou M, Launay N, Ranea-Robles P, Bianchi P, López-Erauskin J, Morató L, Guilera C, Petit B, Vaurs-Barriere C, Guéret-Gonthier C, Bonnet-Dupeyron MN, Fourcade S, Auwerx J, Boespflug-Tanguy O, Pujol A (2017) Oxidative stress and mitochondrial dynamics malfunction are linked in Pelizaeus-Merzbacher disease. Brain Pathol 28:611-30. | LEAK ROUTINE ET | ROX | Intact cells | Human Mouse | Nervous system Fibroblast |
Asseburg 2017 Thesis | 2017 | Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Mouse Rat | Nervous system Other cell lines |
Mantilla 2017 PLOS Pathog | 2017 | Mantilla BS, Marchese L, Casas-Sánchez A, Dyer NA, Ejeh N, Biran M, Bringaud F, Lehane MJ, Acosta-Serrano A, Silber AM (2017) Proline metabolism is essential for Trypanosoma brucei brucei survival in the tsetse vector. PLOS Pathog 13:e1006158. | LEAK OXPHOS ET ROUTINE | S ROX N | Permeabilized cells Intact cells | Protists | |
Bernardinelli 2017 PLoS One | 2017 | Bernardinelli E, Costa R, Scantamburlo G, To J, Morabito R, Nofziger C, Doerrier C, Krumschnabel G, Paulmichl M, Dossena S (2017) Mis-targeting of the mitochondrial protein LIPT2 leads to apoptotic cell death. PLoS One 12(6):e0179591. | LEAK ROUTINE ET | ROX | Intact cells | Human | Kidney |
Boudoures 2017 Thesis | 2017 | Boudoures AL (2017) Mitochondrial damage accumulation in oocytes – a potential link between maternal obesity and increased cardiometabolic disease risk in offspring. PhD Thesis p179. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Mouse | Heart |
Shen 2017 Thesis | 2017 | Shen NY (2017) Characterizing protein arginine methyltransferase expression, localization, and function during myogenesis. Master's Thesis p106. | LEAK OXPHOS | N NS | Permeabilized cells | Mouse | Skeletal muscle |