Cookies help us deliver our services. By using our services, you agree to our use of cookies. More information

Search by property

From Bioblast

This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.

Search by property

Property "Has-20abstract" (as page type) with input value "About-20two-20decades-20ago,-20West-20and-20coworkers-20established-20a-20model-20which-20predicts-20that-20metabolic-20rate-20follows-20a-20three-20quarter-20power-20relationship-20with-20the-20mass-20of-20an-20organism,-20based-20on-20the-20premise-20that-20tissues-20are-20supplied-20nutrients-20through-20a-20fractal-20distribution-20network.-20Quarter-20power-20scaling-20is-20widely-20considered-20a-20universal-20law-20of-20biology-20and-20it-20is-20generally-20accepted-20that-20were-20in-2Dvitro-20cultures-20to-20obey-20allometric-20metabolic-20scaling,-20they-20would-20have-20more-20predictive-20potential-20and-20could,-20for-20instance,-20provide-20a-20viable-20substitute-20for-20animals-20in-20research.-20This-20paper-20outlines-20a-20theoretical-20and-20computational-20framework-20for-20establishing-20quarter-20power-20scaling-20in-20three-2Ddimensional-20spherical-20constructs-20in-2Dvitro,-20starting-20where-20fractal-20distribution-20ends.-20Allometric-20scaling-20in-20non-2Dvascular-20spherical-20tissue-20constructs-20was-20assessed-20using-20models-20of-20Michaelis-20Menten-20oxygen-20consumption-20and-20diffusion.-20The-20models-20demonstrate-20that-20physiological-20scaling-20is-20maintained-20when-20about-205-20to-2060-25-20of-20the-20construct-20is-20exposed-20to-20oxygen-20concentrations-20less-20than-20the-20Michaelis-20Menten-20constant,-20with-20a-20significant-20concentration-20gradient-20in-20the-20sphere.-20The-20results-20have-20important-20implications-20for-20the-20design-20of-20downscaled-20in-2Dvitro-20systems-20with-20physiological-20relevance." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

Showing below up to 0 results starting with #1.

View (previous 50 | next 50) (20 | 50 | 100 | 250 | 500)


    

List of results

No results.