Search by property

This page provides a simple browsing interface for finding entities described by a property and a named value. Other available search interfaces include the page property search, and the ask query builder.

Search by property

Property "Has-20abstract" (as page type) with input value "Cardiomyocyte-20loss-20and-20cardiac-20fibrosis-20are-20the-20main-20characteristics-20of-20cardiac-20ischemia-20and-20heart-20failure,-20and-20mitochondrial-20function-20of-20cardiomyocytes-20is-20impaired-20in-20cardiac-20ischemia-20and-20heart-20failure,-20so-20the-20aim-20of-20this-20study-20is-20to-20identify-20fate-20variability-20of-20cardiomyocytes-20and-20cardiac-20fibroblasts-20with-20mitochondria-20inhibition-20and-20explore-20the-20underlying-20mechanism.-20The-20mitochondrial-20respiratory-20function-20was-20measured-20by-20using-20Oxygraph-2D2k-20high-2Dresolution-20respirometry.-20The-20STAT3-20expression-20and-20activity-20were-20evaluated-20by-20western-20blot.-20Cardiomyocytes-20and-20cardiac-20fibroblasts-20displayed-20different-20morphology.-20The-20mitochondrial-20respiratory-20function-20and-20the-20expressions-20of-20mitochondrial-20complex-20I,-20II,-20III,-20IV,-20and-20V-20of-20cardiac-20fibroblasts-20were-20lower-20than-20that-20of-20cardiomyocytes.-20Mitochondrial-20respiratory-20complex-20I-20inhibitor-20rotenone-20and-20H-3Csub-3E2-3C-2Fsub-3EO-3Csub-3E2-3C-2Fsub-3E-20(100-20µM,-204-20h)-20treatment-20induced-20cell-20death-20of-20cardiomyocyte-20but-20not-20cardiac-20fibroblasts.-20The-20function-20of-20complex-20I-2FII-20was-20impaired-20in-20cardiomycytes-20but-20not-20cardiac-20fibroblasts-20stimulated-20with-20H-3Csub-3E2-3C-2Fsub-3EO-3Csub-3E2-3C-2Fsub-3E-20(100-20µM,-204-20h)-20and-20in-20ischemic-20heart-20of-20mice.-20Rotenone-20and-20H-3Csub-3E2-3C-2Fsub-3EO-3Csub-3E2-3C-2Fsub-3E-20(100-20µM,-204-20h)-20treatment-20reduced-20STAT3-20expression-20and-20activity-20in-20cardiomyocytes-20but-20not-20cardiac-20fibroblasts.-20Inhibition-20of-20STAT3-20impaired-20mitochondrial-20respiratory-20capacity-20and-20exacerbated-20H-3Csub-3E2-3C-2Fsub-3EO-3Csub-3E2-3C-2Fsub-3E-2Dinduced-20cell-20injury-20in-20cardiomycytes-20but-20not-20significantly-20in-20cardiac-20fibroblasts.-20In-20conclusion,-20the-20different-20susceptibility-20of-20cardiomyocytes-20and-20cardiac-20fibroblasts-20to-20mitochondria-20inhibition-20determines-20the-20cell-20fate-20under-20the-20same-20pathological-20stimuli-20and-20in-20which-20STAT3-20plays-20a-20critical-20role." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

Showing below up to 0 results starting with #1.

View (previous 50 | next 50) (20 | 50 | 100 | 250 | 500)

Property: Value:

List of results

No results.