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Property "Has-20abstract" (as page type) with input value "Hydrogen-20sulfide-20(H2S)-20is-20the-20third-20gasotransmitter-20described-20in-20mammals.-20These-20gasotransmitters-20(H2S,-20CO,-20and-20NO)-20are-20small-20molecules-20able-20to-20diffuse-20freely-20across-20membranes-20and-20thus-20susceptible-20to-20reach-20easily-20intracellular-20targets,-20one-20of-20which-20is-20the-20respiratory-20enzyme-20cytochrome-20oxidase-20subject-20to-20complete-20inhibition-20by-20low-20micromolar-20concentrations-20of-20these-20gases.-20However-20in-20contrast-20to-20NO-20or-20CO,-20H2S-20can-20be-20metabolized-20by-20a-20sulfide-20quinone-20reductase-20feeding-20the-20mitochondrial-20respiratory-20chain-20with-20the-20hydrogen-20atoms-20of-20sulfide.-20Sulfide-20is-20thus-20a-20two-2Dsided-20molecule:-20substrate-20or-20poison-20according-20to-20the-20concentration.-20The-20aim-20of-20this-20chapter-20is-20to-20present-20a-20mean-20to-20monitor-20sulfide-20oxidation-20by-20isolated-20mitochondria-20or-20cells-20and-20to-20summarize-20how-20the-20properties-20of-20this-20amazing-20couple-20(mitochondria-20and-20sulfide)-20translate-20into-20practical-20and-20conceptual-20consequences." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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