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• Ezeani 2020 Front Biosci (Schol Ed)
  ...appears that normalisation of altered Kv1.5 channel, an oxygen sensing ion channel and fulfillment of oxygen demand by myocardium might offer a new strategy f
  1 KB (189 words) - 08:30, 16 September 2023
• Viola 2016 JACC: Basic to Translational Science
  ..., Hool LC (2016) The role of the L-type Ca²⁺ channel in altered metabolic activity in a murine model of hypertrophic cardiomyopathy. JACC: Basic to T
  4 KB (531 words) - 15:42, 12 March 2019
• Krabbendam 2020 Cell Death Dis
  ...er BM, Hekimi S, Culmsee C, Eckert GP, Dolga AM (2020) SK channel-mediated metabolic escape to glycolysis inhibits ferroptosis and supports stress resistance in ...oxins. Our findings shed light on metabolic mechanisms promoted through SK channel activation through mitohormesis, which enhances neuronal resilience against
  3 KB (380 words) - 15:39, 29 April 2020
• Viola 2016 J Physiol
  ...n C, Hool L (2016) The L-type Ca²⁺ channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy. J Ph ...y be effective in reducing the cardiomyopathy by normalising mitochondrial metabolic activity.
  4 KB (517 words) - 17:11, 7 November 2016
• Styles 2021 Cell Death Dis
  ...iferation. This study identifies a Kv1.3-mediated mechanism underlying the metabolic regulation of proliferation, which may provide a therapeutic target for dis
  2 KB (261 words) - 15:45, 16 August 2021
• Boutilier 2001 Respir Physiol
  |title=Boutilier RG (2001) Mechanisms of metabolic defense against hypoxia in hibernating frogs. Respir Physiol 128:365-77. ...tation initiates a generalised suppression of ion channel densities and/or channel leak activities. The net result is that cell membrane permeabilities are re
  2 KB (280 words) - 09:28, 9 November 2016
• Stiban 2014 Abstract MiP2014
  |title=Very long chain ceramides interfere with C16 ceramide-induced channel formation: rheostatic control of apoptosis. .../sub>-channel formation in vivo. This interplay between different ceramide metabolic enzymes and their products adds a new dimension to the complexity of mitoch
  3 KB (384 words) - 19:53, 17 August 2014
• Kampjut 2019 Nature
  ...ors, which may have therapeutic potential in ischaemia reperfusion injury, metabolic syndrome and some cancers7-9.
  2 KB (310 words) - 17:38, 20 January 2023
• Tian 2023 Redox Biol
  ...Y, Kong Q, Li J, Xin Y, Wu W, Tang X, Liu X (2023) Voltage-dependent anion channel 1 (VDAC1) overexpression alleviates cardiac fibroblast activation in cardia ...ed to reduced long-chain fatty acid (LCFA) uptake. Voltage-dependent anion channel 1 (VDAC1), the main gatekeeper of the outer mitochondrial membrane (OMM), s
  3 KB (410 words) - 15:36, 11 October 2023
• Gregg 2016 Diabetes
  ...ffset age-associated mitochondrial deficiency with reduced K_ATP channel activity. Diabetes 65:2700-10. ...ce, but not humans, are able to successfully compensate for age-associated metabolic dysfunction by adjusting their β cell glucose sensitivity, and highlight a
  3 KB (381 words) - 14:25, 13 November 2017
• Luo 2012 Cell Res
  ...es. The present results indicate a novel therapeutic strategy for managing metabolic diseases and improving exercise endurance. |keywords=PGC-1α, TRPV-1, High-fat diet-induced metabolic disorders, Exercise capacity
  2 KB (318 words) - 19:34, 29 February 2020
• Briston 2017 Sci Rep
  ...ensitise mitochondria to mPTP opening. Thus, cellular metabolic fluxes and metabolic environment dictate mitochondrial functional response to Ca²⁺ ov
  2 KB (324 words) - 12:54, 10 March 2020
• Angelini 2021 Cell Rep
  ...ed in ischemic or late-stage failing hearts. The mechanism regulating this metabolic switch remains poorly understood. Here, we report that loss of PHD2/3, the ...ial infarction, Prolyl hydroxylase domain protein, Voltage-dependent anion channel
  2 KB (249 words) - 14:28, 12 October 2021
• Ramos 2020 PLoS One
  ...erstand how cytoskeletal disruption in the absence of dystrophin may cause metabolic dysfunctions in skeletal muscle.
  2 KB (308 words) - 15:24, 3 January 2023
• Kataoka 2020 Microbiology Monographs
  ...nd energetics of these respiratory components are summarized and also some metabolic engineering of C. glutamicum to produce valuable chemicals are described re
  2 KB (321 words) - 20:44, 3 November 2023
• Lerchner 2019 Anal Bioanal Chem
  ...der anoxic conditions and with glycolytic inhibitors showed that anaerobic metabolic processes contribute from 30 to 40% to the overall heat production rate. Si
  2 KB (266 words) - 12:24, 9 July 2019
• Phosphorylation pathway
  ...stem, controlling local AMP and ADP concentrations and forming [[metabolic channel]]s. Since substrate-level phosphorylation is involved in the TCA-cycle, the
  2 KB (251 words) - 11:27, 2 June 2020
• Lee 2017 MiPschool Obergurgl
  |title=[[File:LeeHK.jpg|left|90px]] The metabolic syndrome (MetS) - dysmitochondrial syndrome and mitochondrial disruptors. [ ...docrine disrupting chemicals (EDCs), persistent organic pollutants (POPs), metabolic disrupting chemicals (MDCs).
  5 KB (649 words) - 16:10, 12 January 2018
• Gorbacheva 2016 International Symposium Mitochondrial Motility
  ...the content of adenine nucleotides and creatine phosphate against decrease metabolic acidosis and growth of glucose [4]. ...on the functioning of mitochondria, and in particular, on work of mitoKATP channel.
  3 KB (408 words) - 13:03, 7 March 2020
• Miotto 2016 Biochem J
  ...xercise, suggesting that ''in vivo'' activation of voltage-dependent anion channel (VDAC)/adenine nucleotide translocase (ANT) can support mitochondrial ADP t
  3 KB (394 words) - 09:30, 8 November 2016

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