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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (357 entries) 357 500 2 Exercise physiology;nutrition;life style 702 977 3 Comparative MiP;environmental MiP 309 455 4 Pharmacology;toxicology 783 937 5 mt-Biogenesis;mt-density 244 326 6 Genetic knockout;overexpression 583 649 7 Instruments;methods 258 392
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 251 386 2 Alzheimer's 65 89 3 Autism 6 10 4 Cancer 328 437 5 Cardiovascular 182 251 6 COPD 9 12 7 Diabetes 332 434 8 Inherited 61 93 9 Infectious 45 63 10 Myopathy 61 72 11 Neurodegenerative 156 217 12 Obesity 231 373 13 Parkinson's 60 95 14 Sepsis 69 79 15 Other 256 327
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 92 153 2 Cryopreservation 38 61 3 Hypoxia 94 187 4 Ischemia-reperfusion 306 410 5 Oxidative stress;RONS 552 780 6 Permeability transition 71 92 7 Temperature: hypothermia; hyperthermia 90 110
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 6 2 Zebrafish (» Fishes) 11 17 3 Drosophila (» Hexapods) 60 77 4 Caenorhabditis elegans (» Nematodes) 22 30 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 59 83 7 Comparative MiP 309 455
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 12 23 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 12 17 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 108 144 5 Hexapods insects, springtails; » Drosophila 32 41 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 23 40 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 18 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 50 61 12 Plants 32 63 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 37 52 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 42 15 Archaea archaebacteria 0 7
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 166 230 2 Genital 87 118 3 Heart 671 870 4 Kidney 133 165 5 Liver 599 776 6 Lung;Gill 53 73 7 Nervous system 560 676 8 Skeletal muscle 1017 1262
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 233 288 2 Endothelial;epithelial;mesothelial cell 240 275 3 Fibroblast 193 252 4 Islet cell;pancreas;thymus 49 61 5 Leukemia 22 25 6 Lymphocyte 55 73 7 Platelets 110 128 8 Stem cells 35 47
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 15 2 HEK 87 107 3 HeLa 35 52 4 Neuroblastoma 39 44 5 HUVEC 19 22 6 Macrophage-derived cell lines 26 35 7 Other cells and cell lines 284 328
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 48 238 2 Intact organ 22 36 3 Living cells 1061 1192 4 Permeabilized cells 651 684 5 Permeabilized tissue 1025 1111 6 Homogenate 335 373 7 Isolated mitochondria 1169 1460 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 2 10 10 Enzyme 39 74 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 25 2 Complex I CI 448 536 3 Complex II;succinate dehydrogenase CII 394 466 4 Complex III CIII 297 346 5 Complex IV;cytochrome c oxidase CIV 402 473 6 Complex V;ATP synthase CV 218 258 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 57 80 9 Supercomplex 44 60 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 80 105 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 147 197 2 ATP production 75 112 3 Aerobic glycolysis 46 90 4 Amino acid 9 19 5 Calcium 99 167 6 Coupling efficiency;uncoupling 81 146 7 Cyt c Cytochrome c 40 53 8 Fatty acid FA substrate kinetics 120 145 9 Flux control 52 83 10 Inhibitor Inhibitor kinetics 127 158 11 Ion;substrate transport 57 104 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
104 158 13 Oxygen kinetics 102 140 14 Q-junction effect 13 55 15 Redox state 50 85 16 Substrate Fuel substrate kinetics 179 231 17 Temperature Temperature dependence 68 93 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 53 68
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2619 2830 2 R 
ROUTINE respiration
Physiological state, living cells 810 892 3 E 
ET capacity
Maximal noncoupled respiration 1860 1958 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2330 2474
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 547 645 2 N N-pathway control state NADH-linked, level 4 2233 2371 3 S S-pathway control state Succinate-linked, level 3 1520 1601 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 145 166 5 DQ Duorquinol-linked, level 2 23 27 6 CIV Complex IV single step Ascorbate & TMPD, level 1 628 655 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1405 1457 8 Other 129 145 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1344 1394
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1017 1262 2 O2k-Publications: Human heart 671 870 3 O2k-Publications: Skeletal muscle - human vs mouse 36 45
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35