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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling-control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (354 entries) 354 483 2 Exercise physiology;nutrition;life style 638 884 3 Comparative MiP;environmental MiP 296 433 4 Pharmacology;toxicology 688 823 5 mt-Biogenesis;mt-density 232 306 6 Genetic knockout;overexpression 517 575 7 Instruments;methods 216 321
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 232 358 2 Alzheimer's 61 82 3 Autism 3 7 4 Cancer 303 401 5 Cardiovascular 153 219 6 COPD 8 11 7 Diabetes 298 398 8 Inherited 60 81 9 Infectious 37 49 10 Myopathy 55 66 11 Neurodegenerative 145 200 12 Obesity 205 345 13 Parkinson's 52 83 14 Sepsis 61 71 15 Other 228 296
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 88 145 2 Cryopreservation 34 57 3 Hypoxia 74 106 4 Ischemia-reperfusion 294 396 5 Oxidative stress;RONS 531 737 6 Permeability transition 66 87 7 Temperature: hypothermia; hyperthermia 88 105
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 51 66 4 Caenorhabditis elegans (» Nematodes) 19 27 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 72 7 Comparative MiP 296 433
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 10 14 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 100 130 5 Hexapods insects, springtails; » Drosophila 31 40 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 19 29 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 31 43 14 Eubacteria true bacteria, cyanobacteria, spirochetes 23 39 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 152 213 2 Genital 81 110 3 Heart 616 797 4 Kidney 119 147 5 Liver 548 706 6 Lung;Gill 48 63 7 Nervous system 510 610 8 Skeletal muscle 929 1144
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 218 268 2 Endothelial;epithelial;mesothelial cell 221 251 3 Fibroblast 170 216 4 Islet cell;pancreas;thymus 45 55 5 Leukemia 22 25 6 Lymphocyte 48 62 7 Platelets 102 120 8 Stem cells 31 41
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 73 91 3 HeLa 30 43 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 24 33 7 Other cells and cell lines 270 307
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 42 212 2 Intact organ 21 34 3 Living cells 941 1040 4 Permeabilized cells 560 591 5 Permeabilized tissue 940 1024 6 Homogenate 296 331 7 Isolated mitochondria 1081 1350 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 39 68 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 427 511 3 Complex II;succinate dehydrogenase CII 377 446 4 Complex III CIII 288 332 5 Complex IV;cytochrome c oxidase CIV 388 455 6 Complex V;ATP synthase CV 209 247 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 50 71 9 Supercomplex 41 54 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 75 95 11 Uncoupling protein 57 62
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 190 2 ATP production 71 104 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 88 133 6 Coupling efficiency;uncoupling 71 132 7 Cyt c Cytochrome c 38 47 8 Fatty acid FA substrate kinetics 116 140 9 Flux control 46 73 10 Inhibitor Inhibitor kinetics 127 155 11 Ion;substrate transport 54 94 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
97 147 13 Oxygen kinetics 96 127 14 Q-junction effect 6 7 15 Redox state 45 70 16 Substrate Fuel substrate kinetics 175 227 17 Temperature Temperature dependence 59 82 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 52 68
Coupling-control states
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2341 2537 2 R 
ROUTINE respiration
Physiological state, living cells 709 768 3 E 
ET capacity
Maximal noncoupled respiration 1623 1707 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2024 2152
Pathway control states
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 485 579 2 N N-pathway control state NADH-linked, level 4 1977 2097 3 S S-pathway control state Succinate-linked, level 3 1324 1395 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 124 142 5 DQ Duorquinol-linked, level 2 17 21 6 CIV Complex IV single step Ascorbate & TMPD, level 1 558 584 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1231 1277 8 Other 123 139 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1136 1178
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 929 1144 2 O2k-Publications: Human heart 616 797 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 27 33
