From Bioblast
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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (334 entries) 334 455 2 Exercise physiology;nutrition;life style 597 817 3 Comparative MiP;environmental MiP 286 422 4 Pharmacology;toxicology 579 681 5 mt-Biogenesis;mt-density 230 302 6 Genetic knockout;overexpression 468 526 7 Instruments;methods 201 296
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 217 330 2 Alzheimer's 55 75 3 Autism 2 4 4 Cancer 279 371 5 Cardiovascular 140 184 6 COPD 8 10 7 Diabetes 279 367 8 Inherited 53 73 9 Infectious 27 32 10 Myopathy 52 62 11 Neurodegenerative 135 184 12 Obesity 179 281 13 Parkinson's 52 81 14 Sepsis 56 65 15 Other 200 264
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 76 126 2 Cryopreservation 33 56 3 Hypoxia 66 96 4 Ischemia-reperfusion 278 379 5 Oxidative stress;RONS 500 698 6 Permeability transition 54 73 7 Temperature: hypothermia; hyperthermia 85 102
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 10 15 3 Drosophila (» Hexapods) 47 61 4 Caenorhabditis elegans (» Nematodes) 15 22 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 50 68 7 Comparative MiP 286 422
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 10 20 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 94 123 5 Hexapods insects, springtails; » Drosophila 28 37 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 18 28 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 44 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 26 38 14 Eubacteria true bacteria, cyanobacteria, spirochetes 19 35 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 139 182 2 Genital 76 105 3 Heart 572 744 4 Kidney 112 139 5 Liver 520 673 6 Lung;Gill 45 57 7 Nervous system 486 582 8 Skeletal muscle 865 1073
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 186 233 2 Endothelial;epithelial;mesothelial cell 200 229 3 Fibroblast 162 207 4 Islet cell;pancreas;thymus 40 50 5 Lymphocyte 51 64 6 Platelet 91 107 7 Stem cells 24 34
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 67 84 3 HeLa 26 39 4 Neuroblastoma 30 33 5 HUVEC 19 22 6 Macrophage-derived cell lines 22 31 7 Other cells and cell lines 255 292
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 38 159 2 Intact organ 21 33 3 Living cells 852 947 4 Permeabilized cells 504 532 5 Permeabilized tissue 870 953 6 Homogenate 266 299 7 Isolated mitochondria 1013 1276 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 38 66 11 Oxidase and biochemical oxidation 36 46
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 23 2 Complex I CI 411 495 3 Complex II;succinate dehydrogenase CII 365 433 4 Complex III CIII 277 321 5 Complex IV;cytochrome c oxidase CIV 376 442 6 Complex V;ATP synthase CV 201 239 7 mt-Inner membrane transporter 29 41 8 Marker enzyme 48 68 9 Supercomplex 40 52 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 70 89 11 Uncoupling protein 54 59
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 144 187 2 ATP production 64 96 3 Aerobic glycolysis 39 74 4 Amino acid 9 18 5 Calcium 71 103 6 Coupling efficiency;uncoupling 68 127 7 Cyt c Cytochrome c 36 44 8 Fatty acid FA substrate kinetics 112 134 9 Flux control 45 70 10 Inhibitor Inhibitor kinetics 126 154 11 Ion;substrate transport 48 87 12 mt-Membrane potential Mitochondrial membrane potential
- » Keywords: Force and membrane potential
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
88 136 13 Oxygen kinetics 91 122 14 Q-junction effect 6 7 15 Redox state 45 69 16 Substrate Fuel substrate kinetics 170 221 17 Temperature Temperature dependence 57 80 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 51 66
Coupling control states
# O2k-Publications MitoPedia: Coupling control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2156 2351 2 R 
ROUTINE respiration
Physiological state, living cells 644 702 3 E 
ET-capacity
Maximal noncoupled respiration 1472 1553 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1800 1927
Pathway control states
# O2k-Publications MitoPedia: Electron transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 444 537 2 N N-pathway control state NADH-linked, level 4 1789 1908 3 S S-pathway control state Succinate-linked, level 3 1205 1275 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 104 121 5 DQ Duorquinol-linked, level 2 16 19 6 CIV Complex IV single step Ascorbate & TMPD, level 1 505 530 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1105 1150 8 Other 121 136 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1000 1041
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 865 1073 2 O2k-Publications: Human heart 572 744 3 O2k-Publications: Skeletal muscle - human vs mouse 35 43
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 25 31
