From Bioblast
|
|
|
|
|
|
|
NextGen-O2k |
O2k-Publications: Topics
- Mitochondria and cell research
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (325 entries) 325 444 2 Exercise physiology;nutrition;life style 540 719 3 Comparative MiP;environmental MiP 259 385 4 Pharmacology;toxicology 506 586 5 mt-Biogenesis;mt-density 226 292 6 Genetic knockout;overexpression 406 460 7 Instruments;methods 187 284
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 204 307 2 Alzheimer's 54 72 3 Autism 2 2 4 Cancer 256 340 5 Cardiovascular 129 167 6 COPD 8 10 7 Diabetes 251 324 8 Inherited 51 70 9 Infectious 25 30 10 Myopathy 46 55 11 Neurodegenerative 134 180 12 Obesity 167 225 13 Parkinson's 50 75 14 Sepsis 55 64 15 Other 173 233
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 73 129 2 Cryopreservation 31 55 3 Hypoxia 59 87 4 Ischemia-reperfusion 268 368 5 Oxidative stress;RONS 470 665 6 Permeability transition 51 68 7 Temperature: hypothermia; hyperthermia 80 96
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 3 4 2 Zebrafish (» Fishes) 7 12 3 Drosophila (» Hexapods) 40 53 4 Caenorhabditis elegans (» Nematodes) 10 17 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 69 7 Comparative MiP 259 385
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 10 20 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 90 120 5 Hexapods insects, springtails; » Drosophila 26 34 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 17 34 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 16 26 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 10 14 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 47 58 12 Plants 26 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 26 38 14 Eubacteria true bacteria, cyanobacteria, spirochetes 18 34 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 124 153 2 Genital 67 91 3 Heart 539 705 4 Kidney 107 134 5 Liver 479 626 6 Lung;Gill 40 53 7 Nervous system 461 555 8 Skeletal muscle 792 985
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 177 223 2 Endothelial;epithelial;mesothelial cell 181 209 3 Fibroblast 156 200 4 Islet cell;pancreas;thymus 39 49 5 Lymphocyte 46 58 6 Platelet 82 96 7 Stem cells 23 33
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 63 82 3 HeLa 24 36 4 Neuroblastoma 23 24 5 HUVEC 19 22 6 Macrophage-derived cell lines 20 29 7 Other cells and cell lines 229 270
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 38 107 2 Intact organ 20 31 3 Living cells 781 876 4 Permeabilized cells 456 485 5 Permeabilized tissue 796 875 6 Homogenate 240 273 7 Isolated mitochondria 937 1196 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 38 66 11 Oxidase and biochemical oxidation 36 46
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 19 23 2 Complex I CI 381 462 3 Complex II;succinate dehydrogenase CII 339 408 4 Complex III CIII 254 299 5 Complex IV;cytochrome c oxidase CIV 354 420 6 Complex V;ATP synthase CV 182 222 7 mt-Inner membrane transporter 28 38 8 Marker enzyme 48 69 9 Supercomplex 36 47 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 62 80 11 Uncoupling protein 48 54
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 137 178 2 ATP production 58 91 3 Aerobic glycolysis 39 74 4 Amino acid 6 15 5 Calcium 63 93 6 Coupling efficiency;uncoupling 68 126 7 Cyt c Cytochrome c 37 45 8 Fatty acid FA substrate kinetics 106 127 9 Flux control 43 68 10 Inhibitor Inhibitor kinetics 119 146 11 Ion;substrate transport 45 82 12 mt-Membrane potential Mitochondrial membrane potential
- » Keywords: Force and membrane potential
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
78 127 13 Oxygen kinetics 86 116 14 Q-junction effect 5 6 15 Redox state 44 68 16 Substrate Fuel substrate kinetics 167 218 17 Temperature Temperature dependence 51 74 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 50 65
Coupling control states
# O2k-Publications MitoPedia: Coupling control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 1985 2168 2 R 
ROUTINE respiration
Physiological state, living cells 591 650 3 E 
ET-capacity
Maximal noncoupled respiration 1346 1429 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1571 1691
Pathway control states
# O2k-Publications MitoPedia: Electron transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 408 501 2 N N-pathway control state NADH-linked, level 4 1614 1718 3 S S-pathway control state Succinate-linked, level 3 1079 1147 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 98 115 5 DQ Duorquinol-linked, level 2 14 17 6 CIV Complex IV single step Ascorbate & TMPD, level 1 463 489 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 999 1041 8 Other 120 134 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 893 934
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 792 985 2 O2k-Publications: Human heart 539 705 3 O2k-Publications: Skeletal muscle - human vs mouse 31 40
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 17 26
