From Bioblast
O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (357 entries) 357 500 2 Exercise physiology;nutrition;life style 719 995 3 Comparative MiP;environmental MiP 313 463 4 Pharmacology;toxicology 807 964 5 mt-Biogenesis;mt-density 245 327 6 Genetic knockout;overexpression 613 679 7 Instruments;methods 263 398
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 260 395 2 Alzheimer's 68 92 3 Autism 7 11 4 Cancer 336 447 5 Cardiovascular 192 261 6 COPD 9 12 7 Diabetes 339 441 8 Inherited 61 94 9 Infectious 47 65 10 Myopathy 68 79 11 Neurodegenerative 160 222 12 Obesity 241 383 13 Parkinson's 64 100 14 Sepsis 71 81 15 Other 269 341
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 92 154 2 Cryopreservation 38 61 3 Hypoxia 101 196 4 Ischemia-reperfusion 318 422 5 Oxidative stress;RONS 561 794 6 Permeability transition 71 94 7 Temperature: hypothermia; hyperthermia 90 110
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 5 7 2 Zebrafish (» Fishes) 14 20 3 Drosophila (» Hexapods) 62 79 4 Caenorhabditis elegans (» Nematodes) 23 31 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 60 84 7 Comparative MiP 313 463
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 13 24 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 13 18 3 Amphibians frogs, toads, salamanders 10 15 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 110 146 5 Hexapods insects, springtails; » Drosophila 32 41 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 39 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 20 8 Molluscs gastropods, cephalopods, bivalves 24 41 9 Nematodes » Caenorhabditis elegans 5 11 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 18 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 51 62 12 Plants 33 65 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 40 57 14 Eubacteria true bacteria, cyanobacteria, spirochetes 24 44 15 Archaea archaebacteria 0 7
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 177 241 2 Genital 91 122 3 Heart 691 890 4 Kidney 138 170 5 Liver 618 795 6 Lung;Gill 55 75 7 Nervous system 577 695 8 Skeletal muscle 1049 1299
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 235 290 2 Endothelial;epithelial;mesothelial cell 248 283 3 Fibroblast 197 257 4 Islet cell;pancreas;thymus 53 64 5 Leukemia 22 25 6 Lymphocyte 56 74 7 Platelets 117 135 8 Stem cells 36 48
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 15 2 HEK 89 110 3 HeLa 36 53 4 Neuroblastoma 42 48 5 HUVEC 19 22 6 Macrophage-derived cell lines 26 35 7 Other cells and cell lines 290 336
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 51 245 2 Intact organ 22 36 3 Living cells 1099 1235 4 Permeabilized cells 680 713 5 Permeabilized tissue 1059 1148 6 Homogenate 353 391 7 Isolated mitochondria 1208 1501 8 SMP Submitochondrial particles 10 28 9 Chloroplasts 3 11 10 Enzyme 39 74 11 Oxidase and biochemical oxidation 38 48
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 21 26 2 Complex I CI 454 559 3 Complex II;succinate dehydrogenase CII 395 467 4 Complex III CIII 298 353 5 Complex IV;cytochrome c oxidase CIV 402 477 6 Complex V;ATP synthase CV 219 262 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 57 80 9 Supercomplex 45 66 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 81 106 11 Uncoupling protein 59 64
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 148 200 2 ATP production 78 117 3 Aerobic glycolysis 48 92 4 Amino acid 9 19 5 Calcium 101 172 6 Coupling efficiency;uncoupling 81 156 7 Cyt c Cytochrome c 39 52 8 Fatty acid FA substrate kinetics 120 145 9 Flux control 53 85 10 Inhibitor Inhibitor kinetics 127 159 11 Ion;substrate transport 60 107 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
- Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
107 162 13 Oxygen kinetics 103 142 14 Q-junction effect 13 55 15 Redox state 50 85 16 Substrate Fuel substrate kinetics 179 231 17 Temperature Temperature dependence 70 95 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 54 69
Coupling-control
# O2k-Publications MitoPedia: Coupling-control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2726 2939 2 R 
ROUTINE respiration
Physiological state, living cells 839 922 3 E 
ET capacity
Maximal noncoupled respiration 1944 2042 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 2451 2596
Pathway control
# O2k-Publications MitoPedia: Electron-transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 571 670 2 N N-pathway control state NADH-linked, level 4 2336 2475 3 S S-pathway control state Succinate-linked, level 3 1586 1667 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 150 172 5 DQ Duorquinol-linked, level 2 23 27 6 CIV Complex IV single step Ascorbate & TMPD, level 1 660 687 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1478 1530 8 Other 130 146 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1424 1474
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 1049 1299 2 O2k-Publications: Human heart 691 890 3 O2k-Publications: Skeletal muscle - human vs mouse 37 46
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 29 35
