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O2k-Publications: Topics
- Mitochondria and Cell Research - the Oroboros Ecosystem
Contents
- 1 Mitochondrial physiology: MiP areas
- 2 Pathological states
- 3 Stress conditions
- 4 Organisms
- 5 Tissues and cells
- 6 Preparations
- 7 Enzymes
- 8 Regulation
- 9 Coupling control states
- 10 Pathway control states
- 11 MiPMap combinations - examples
- 12 O2k-Manuals and protocols and specific instrumental applications
Mitochondrial physiology: MiP areas
# O2k-Publications MitoPedia: Comment O2k Total 1 mt-Medicine (353 entries) 353 480 2 Exercise physiology;nutrition;life style 615 859 3 Comparative MiP;environmental MiP 287 423 4 Pharmacology;toxicology 650 782 5 mt-Biogenesis;mt-density 230 304 6 Genetic knockout;overexpression 489 547 7 Instruments;methods 203 298
Pathological states
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Aging;senescence 222 347 2 Alzheimer's 59 80 3 Autism 2 6 4 Cancer 289 387 5 Cardiovascular 145 208 6 COPD 8 11 7 Diabetes 284 383 8 Inherited 60 81 9 Infectious 31 38 10 Myopathy 53 64 11 Neurodegenerative 142 197 12 Obesity 185 320 13 Parkinson's 52 82 14 Sepsis 59 69 15 Other 211 278
Stress conditions
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Cell death White, brown, beige fat tissue 84 141 2 Cryopreservation 33 56 3 Hypoxia 67 99 4 Ischemia-reperfusion 285 387 5 Oxidative stress;RONS 515 720 6 Permeability transition 61 81 7 Temperature: hypothermia; hyperthermia 85 102
Organisms
- Mammals
- Model organisms
# O2k-Publications MitoPedia: Comment O2k Total 1 Chicken (» Birds) 4 5 2 Zebrafish (» Fishes) 11 16 3 Drosophila (» Hexapods) 48 63 4 Caenorhabditis elegans (» Nematodes) 17 25 5 Artemia (» Crustaceans) 11 18 6 Saccharomyces cerevisiae (» Fungi) 52 72 7 Comparative MiP 287 423
- Non-mammals
# O2k-Publications MitoPedia: Comment O2k Total 1 Birds (» Chicken) 11 21 2 Reptiles turtles, lizards, snakes, crocodiles, alligators 10 14 3 Amphibians frogs, toads, salamanders 9 13 4 Fishes bony fishes, carilaginous fishes (sharks, rays, skates) and jawless fishes (hagfish, lampreys); » Zebrafish 97 126 5 Hexapods insects, springtails; » Drosophila 29 38 6 Crustaceans crabs, shrimp, barnacles, etc.; » Artemia 19 37 7 Annelids polychaetes, e.g. lugworm Arenicola marina, oligochaetes, leeches 3 16 8 Molluscs gastropods, cephalopods, bivalves 18 28 9 Nematodes » Caenorhabditis elegans 3 8 10 Other invertebrates urocordates (e.g. ascidians, sea squirts); cephalochordates (amphioxus, lancelets); echinoderms; chelicerates (e.g. spiders, scorpions, horseshoe crabs); myriapods (millipedes, centipedes); gastrotrichs; rotifers; ctenophores; nemerteans; tardigrades; platyhelminthes; cnidaria; porifera; ... 11 15 11 Fungi yeast, molds, mushrooms, etc.; » Saccharomyces cerevisiae 48 59 12 Plants 25 45 13 Protists amoebas, ciliates, trypanosomes, dinoflagellates, diatoms, green algae, etc. 28 40 14 Eubacteria true bacteria, cyanobacteria, spirochetes 21 37 15 Archaea archaebacteria 0 6
Tissues and cells
- Tissues - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Fat White, brown, beige fat tissue 146 206 2 Genital 77 106 3 Heart 589 768 4 Kidney 115 143 5 Liver 530 686 6 Lung;Gill 46 60 7 Nervous system 494 592 8 Skeletal muscle 892 1107
- Cell types - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Blood cells 210 260 2 Endothelial;epithelial;mesothelial cell 207 237 3 Fibroblast 167 213 4 Islet cell;pancreas;thymus 42 52 5 Leukemia 23 26 6 Lymphocyte 48 62 7 Platelets 99 117 8 Stem cells 30 40
- Cell lines - alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 CHO 13 13 2 HEK 68 86 3 HeLa 27 40 4 Neuroblastoma 32 35 5 HUVEC 19 22 6 Macrophage-derived cell lines 22 31 7 Other cells and cell lines 265 302
Preparations
# O2k-Publications MitoPedia: Comment O2k Total 1 Living organism 38 199 2 Intact organ 21 34 3 Living cells 891 989 4 Permeabilized cells 526 555 5 Permeabilized tissue 896 979 6 Homogenate 277 310 7 Isolated mitochondria 1044 1309 8 SMP Submitochondrial particles 9 21 9 Chloroplasts 1 9 10 Enzyme 38 66 11 Oxidase and biochemical oxidation 37 47
Enzymes
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 Adenine nucleotide translocase ANT 20 24 2 Complex I CI 419 503 3 Complex II;succinate dehydrogenase CII 369 437 4 Complex III CIII 282 326 5 Complex IV;cytochrome c oxidase CIV 381 448 6 Complex V;ATP synthase CV 205 243 7 mt-Inner membrane transporter 31 43 8 Marker enzyme 49 69 9 Supercomplex 40 53 10 TCA cycle and matrix dehydrogenases Tricarboxylic acid cycle 74 94 11 Uncoupling protein 57 62
Regulation
- Alphabetical order
# O2k-Publications MitoPedia: Comment O2k Total 1 ADP ADP kinetics 145 189 2 ATP production 69 102 3 Aerobic glycolysis 41 76 4 Amino acid 9 18 5 Calcium 85 119 6 Coupling efficiency;uncoupling 70 130 7 Cyt c Cytochrome c 37 46 8 Fatty acid FA substrate kinetics 115 139 9 Flux control 46 71 10 Inhibitor Inhibitor kinetics 128 156 11 Ion;substrate transport 51 91 12 mt-Membrane potential Mitochondrial membrane potential
- Bioblast links: Force and membrane potential - >>>>>>> - Click on [Expand] or [Collapse] - >>>>>>>
.::: Fundamental relationships
- mt-Membrane potential and protonmotive force
- O2k-Potentiometry
- » O2k-Catalogue: O2k-TPP+ ISE-Module
- » O2k-Manual: MiPNet15.03 O2k-MultiSensor-ISE
- » TPP - O2k-Procedures: Tetraphenylphosphonium
- » Specifications: MiPNet15.08 TPP electrode
- » Poster
- » Unspecific binding of TPP+
- » TPP+ inhibitory effect
- O2k-Potentiometry
- O2k-Fluorometry
- » O2k-Catalogue: O2k-FluoRespirometer
- » O2k-Manual: MiPNet22.11 O2k-FluoRespirometer manual
- » Safranin - O2k-Procedures: MiPNet20.13 Safranin mt-membranepotential / Safranin
- » TMRM - O2k-Procedures: TMRM
- O2k-Fluorometry
- O2k-Publications
91 139 13 Oxygen kinetics 95 126 14 Q-junction effect 6 7 15 Redox state 45 69 16 Substrate Fuel substrate kinetics 173 224 17 Temperature Temperature dependence 57 80 18 Threshold;excess capacity 27 30 19 Uncoupler Uncoupler kinetics 51 66
Coupling control states
# O2k-Publications MitoPedia: Coupling control states Comment O2k Total 1 P 
OXPHOS capacity
Oxidative phosphorylation capacity, saturating [ADP] 2230 2425 2 R 
ROUTINE respiration
Physiological state, living cells 669 728 3 E 
ET-capacity
Maximal noncoupled respiration 1533 1615 4 L 
LEAK respiration
Resting state, non-phosphorylating respiration 1887 2014
Pathway control states
# O2k-Publications MitoPedia: Electron transfer-pathway states Comment O2k Total 1 F F-pathway control state Fatty acid oxidation, level 5 459 552 2 N N-pathway control state NADH-linked, level 4 1865 1984 3 S S-pathway control state Succinate-linked, level 3 1256 1326 4 Gp Gp-pathway control state Glycerophosphate-linked, level 3 115 132 5 DQ Duorquinol-linked, level 2 17 20 6 CIV Complex IV single step Ascorbate & TMPD, level 1 530 555 7 NS NS-pathway control state Convergent CI- and CII-linked electron flow to the Q-junction 1151 1196 8 Other 123 138 9 ROX 
Residual oxygen consumption
includes non-mitochondrial respiration 1062 1103
MiPMap combinations - examples
- Examples for specific combinations
# O2k-Publications MitoPedia: Comment O2k Total 1 O2k-Publications: Human skeletal muscle 892 1107 2 O2k-Publications: Human heart 589 768 3 O2k-Publications: Skeletal muscle - human vs mouse 36 44
- Browse data
O2k-Manuals and protocols and specific instrumental applications
# O2k-Publications MitoPedia: Comment O2k Total 1 Twin-Flow respirometry 0 21 2 Separate DatLab applications 26 32
