OROBOROS INSTRUMENTS

»Oroboros Ecosystem«

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Oroboros Ecosystem Agenda - 2021 week 8

2021 Week 8

• Feb-22 Mo

Exploring the Q-junction in real-time Simultaneous measurement of coenzyme Q redox state and respiration in isolated mitochondria: Komlodi T, Cardoso LHD, Doerrier C, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. MitoFit Preprints 2021.2. doi:10.26124/mitofit:2021-0002

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• Feb-23 Tu - ÖGMBT Life Science Tuesdays

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• Feb-24 We

Anticancer effect of metformin in myeloproliferative neoplasms: downregulation of JAK2/STAT signaling and mitochondrial activity from the O2k-Network »BR Ribeirao Preto Alberici LC«  Machado-Neto JA, Fenerich BA, Scopim-Ribeiro R, Eide CA, Coelho-Silva JL, Dechandt CRP, Fernandes JC, Rodrigues Alves APN, Scheucher PS, Simões BP, Alberici LC, de Figueiredo Pontes LL, Tognon CE, Druker BJ, Rego EM, Traina F (2018) Metformin exerts multitarget antileukemia activity in JAK2V617F-positive myeloproliferative neoplasms. Cell Death Dis 9:311. »Bioblast link«

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• Feb-25 Th

Diagnosis of mitochondrial disease in frozen samples Measurement of respiratory function in cryopreserved muscle biopsies: Zuccolotto-dos-Reis FH, Andriao-Escarso SH, Araujo JS, Espreafico EM, Alberici LC, Sobreira CFR (2021) Acetyl CoA driven respiration in frozen muscle contributes to the diagnosis of mitochondrial disease. MitoFit Preprints 2021.3. doi:10.26124/mitofit:2021-0003

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• Feb-26 Fr

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• Feb-27 Sa

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• Feb-28 Su Rare disease day

Wolframin deficiency-related changes in the bioenergetics of mouse muscle from the O2k-Network »EE Tallinn Kaambre T« »EE Tartu Paju K«  Tepp K, Puurand M, Timohhina N, Aid-Vanakova J, Reile I, Shevchuk I, Chekulayev V, Eimre M, Peet N, Kadaja L, Paju K, Kaambre T (2020) Adaptation of striated muscles to Wolframin deficiency in mice: Alterations in cellular bioenergetics. Biochim Biophys Acta Gen Subj 1864:129523. »Bioblast link«

Oroboros of the month

Oroboros cycle The Ouroboros represents the perpetual cyclic renewal of life and infinity, the concept of eternity and the eternal return, and represents the cycle of life, death and rebirth, leading to immortality, as in the phoenix. Oroboros pictures of the month page

In focus

• MitoEAGLE Mitochondrial Physiology and Blue Book MitoPathways Poster
  

- »MitoEAGLE Task Group BEC 2020.1

- »Gnaiger 2020 MitoPathways BEC 2020.2« 

Stay alert

Bioblast alert 2021

MitoPedia alert - Currently Asked Questions

O2k-Publications alert

O2k-Open Support alert - Currently Asked Questions

Oroboros Agenda In Focus

Funding acknowledgments

Next Oroboros Ecosystem Agenda 2021

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2021 Week 9

• Mar-1 Mo

Complex I of the mitochondrial electron transfer system is an important druggable target in Alzheimer's disease from the O2k-Network »US NY New York Galkin A«  Stojakovic A, Trushin S, Sheu A, Khalili L, Chang SY, Li X, Christensen T, Salisbury JL, Geroux RE, Gateno B, Flannery PJ, Dehankar M, Funk CC, Wilkins J, Stepanova A, O'Hagan T, Galkin A, Nesbitt J, Zhu X, Tripathi U, Macura S, Tchkonia T, Pirtskhalava T, Kirkland JL, Kudgus RA, Schoon RA, Reid JM, Yamazaki Y, Kanekiyo T, Zhang S, Nemutlu E, Dzeja P, Jaspersen A, Kwon YIC, Lee MK, Trushina E (2021) Partial inhibition of mitochondrial complex I ameliorates Alzheimer's disease pathology and cognition in APP/PS1 female mice. Commun Biol 4:61. »Bioblast link«

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• Mar-2 Tu

Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate In the absence of malate, accumulation of Acetyl-CoA inhibits FAO. - »Fatty acid oxidation pathway control state«, »Mitochondrial Pathways: Chapter 5«  - communicated by »Cecatto Cristiane« and »Cardoso Luiza«

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• Mar-3 We

»FAT4BRAIN O2k-Workshop IOC148 Virtual Event« (Mar 3-4)

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• Mar-4 Th

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• Mar-05 Fr

2021 Week 10

• Mar-08 Mo

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• Mar-09 Tu - ÖGMBT Life Science Tuesdays

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• Mar-10 We

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• Mar-11 Th

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• Mar-12 Fr

2021 Week 11

• Mar-15 Mo

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• Mar-16 Tu

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• Mar-17 We

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• Mar-18 Th

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• Mar-19 Fr

2021 Week 12 

• Mar-22 Mo

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• Mar-23 Tu - ÖGMBT Life Science Tuesdays

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• Mar-24 We

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• Mar-25 Th

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• Mar-26 Fr

2021 Week 13

• Mar-29 Mo

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• Apr-2 Fr

2021 Week 14

• Apr-05 Mo

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2021 Week 15

• Apr-12 Mo

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2021 Week 16

• Apr-19 Mo

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2021 Week 17

• Apr-26 Mo

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• Apr-30 Fr

2021 Week 18

• May-03 Mo

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• May-07 Fr

2021 Week 19

• May-10 Mo

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• May-14 Fr

2021 Week 20

• May-17 Mo

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• May-21 Fr

2021 Week 21

• May-24 Mo

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• May-28 Fr

2021 Week 22

• May-31 Mo

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• Jun-01 Tu

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2021 Week 23

• Jun-07 Mo

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• Jun-11 Fr

2021 Week 24

• Jun-14 Mo

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2021 Week 25

• Jun-21 Mo

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2021 Week 26 

• Jun-28 Mo

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2021 Week 27

• Jul-05 Mo

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2021 Week 28

• Jul-12 Mo

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2021 Week 29

• Jul-19 Mo

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2021 Week 30

• Jul-26 Mo

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2021 Week 31

• Aug-02 Mo

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2021 Week 32

• Aug-09 Mo

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• Aug-13 Fr

2021 Week 33  

• Aug-16 Mo

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• Aug-20 Fr

2021 Week 34

• Aug-23 Mo

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• Aug-27 Fr

2021 Week 35 

• Aug-30 Mo

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• Aug-31 Tu

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2021 Week 36 

• Sep-06 Mo

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• Sep-07 Tu

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• Sep-10 Fr

2021 Week 37

• Sep-13 Mo

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• Sep-14 Tu

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• Sep-17 Fr

2021 Week 38

• Sep-20 Mo

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• Sep-21 Tu

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• Sep-24 Fr

2021 Week 39 

• Sep-27 Mo

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• Oct-01 Fr

2021 Week 40

• Oct-04 Mo

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2021 Week 41

• Oct-11 Mo

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• Oct-15 Fr

2021 Week 42

• Oct-18 Mo

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• Oct-22 Fr

2021 Week 43

• Oct-25 Mo

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• Oct-29 Fr

2021 Week 44

• Nov-01 Mo

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• Nov-05 Fr

2021 Week 45

• Nov-08 Mo

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• Nov-12 Fr

2021 Week 46

• Nov-15 Mo

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2021 Week 47

• Nov-22 Mo

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• Nov-26 Fr

2021 Week 48

• Nov-29 Mo

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• Dec-03 Fr

2021 Week 49

• Dec-06 Mo

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2021 Week 50

• Dec-13 Mo

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• Dec-17 Fr

2021 Week 51

• Dec-20 Mo

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• Dec-24 Fr

2021 Week 52

• Dec-27 Mo

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• Dec-28 Tu

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• Dec-29 We

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• Dec-31 Fr

Last week and before

» Oroboros Ecosystem Agenda 2021 Archive

» Oroboros Ecosystem Agenda 2020 Archive