OROBOROS INSTRUMENTS

Bioblast Agenda - 2023 week 22

Oroboros declares solidarity against the Russian aggression-war in Ukraine.

2023 Week 22

May- 29 Mo

May- 30 Tu

Registration deadline for »EUROMIT2023 Bologna IT«

May- 31 We

Measuring fatty acid oxidation (FAO)-linked respiration requires a low concentration of malate

In the absence of malate, accumulation of Acetyl-CoA inhibits FAO.
- »Fatty acid oxidation pathway control state«, »Mitochondrial Pathways: Chapter 5«
- communicated by »Cecatto Cristiane« and »Cardoso Luiza«

Jun- 01 Th

Jun- 02 Fr

Oroboros of the month

Ceiling decoration (detail) - 1683-85 Fresco - Palazzo Medici Riccardi, Florence

The picture shows one of the ends of the ceiling in the Galleria Riccardiana (opposite to the entrance) reproduce the Cave of Eternity. Giordano presents a gathering of mythological figures associated with time and mortality. They are encircled by an Ouroboros, which symbolises Eternity.

(photo by Elettra Leo)).

» Oroboros pictures of the month

In focus

MiPschool2023 and
15^th MiPconference: Bioenergetics Communications on mitObesity

Dates: 2023 July 23-27 and July 27-30

Location: Obergurgl, Austria

» Abstract submission - open until fully booked
» Registration

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Bioblast: About

Bioblast is an open access platform, including MitoPedia as a glossary and index for mitochondrial and chloroplast physiology, hosting MitoGlobal, and supporting the journal Bioenergetics Communications and the Oroboros Ecosystem.
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2023 Week 23

Jun- 05 Mo

Jun- 06 Tu

»Health Innovation Summit 2023 Vienna AT«

13:30-14:30 Erich Gnaiger discussion panel member at Health Innovation Summit 2023 Vienna AT - The BMI gender data gap: Cellular energy metabolism is fired by mitochondria. Their respiratory capacity decreases with obesity. But the WHO defines obesity with an adult-white-male medicine bias inherent in the body mass index.

Jun- 07 We

»ESCI 2023 Prague CZ« Jun 7-9

Jun- 08 Th

»International GIBB Meeting 2023 Riva del Garda IT« Jun 8-10

13:00 Baglivo Eleonora poster session at ESCI 2023 Prague CZ - The cytochrome c test for respirometric quality control of the integrity of the mitochondrial outer membrane - Session S01 - Mitochondrial Biology

13:00 Leo Elettra poster session at ESCI 2023 Prague CZ - High-resolution respirometry is comparable in 0.5 mL and 2.0 mL chamber volumes: studies with platelets, permeabilized fibroblasts, and isolated mitochondria - Session S01 - Mitochondrial Biology

16:00-16:15 Timon-Gomez Alba oral presentation at International GIBB Meeting 2023 Riva del Garda IT - A reference substrate-uncoupler-inhibitor titration protocol to create a mitochondrial pathway and coupling control database - Session 1 - Redox reactions and dynamics of energy-transducing membranes

Jun- 09 Fr

14:30-15:00 Gnaiger Erich Plenary lecture 3 at International GIBB Meeting 2023 Riva del Garda IT - Nonlinearity of the proton leak and membrane potential - protonmotive pressure as a unifying concept

Jun- 10 Sa

Jun- 11 Su

»EUROMIT2023 Bologna IT« Jun 11-15

2023 Week 24

Jun- 12 Mo

»EUROMIT2023 Bologna IT« Jun 11-15

15:30 Timon-Gomez Alba poster session at EUROMIT2023 Bologna IT - Mitochondrial injury in warm ischemia studied by high-resolution respirometry - Session topic: Modelling pathogenic mechanisms: OXPHOS, metabolic rewiring and tissue specificity

18:00 Gnaiger Erich poster session at EUROMIT2023 Bologna IT - Off-target effects of etomoxir: inhibition of mitochondrial Complex I and fatty acid oxidation - Session topic: Modelling pathogenic mechanisms: OXPHOS, metabolic rewiring and tissue specificity

Jun- 13 Tu

12:45-13:45 Gnaiger Erich lunch workshop at EUROMIT2023 Bologna IT - Mitochondrial bioenergetics - a quantitative analytical and diagnostic approach - Sala Europa

Jun- 14 We

Jun- 15 Th

"Obesity has an opposing association with mitochondrial respiration in adipose- and liver tissue with no overall association with NAFLD (nonalcoholic fatty liver disease) severity."

Pedersen JS, Rygg MO, Chrøis K, Sustarsic EG, Gerhart-Hines Z, Wever Albrechtsen NJ, Serizawa RR, Kristiansen VB, Basse AL, Boilesen AEB, Olsen BH, Hansen T, Gluud LL, Madsbad S, Larsen S, Bendtsen F, Dela F (2022) Influence of NAFLD and bariatric surgery on hepatic and adipose tissue mitochondrial biogenesis and respiration. »Bioblast link«

from the O2k-Network »DK Copenhagen Gerhart-Hines Z« and »DK Copenhagen Larsen S«

Jun- 16 Fr

2023 Week 25

Jun- 19 Mo

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

Jun- 20 Tu

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

Decline of mitochondrial fitness in overweight states is a biomarker of the systemic mitObesity syndrome, providing a mechanistic link between common obesity and associated chronic comorbidities.

Body mass excess provides an evidence-based index of underweight, overweight and obesity across all heights and ages, applicable to all populations for which the healthy reference baseline is established.
- »Body mass excess and mitObesity«

Jun- 21 We

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

Jun- 22 Th

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

"BAM15 is a tolerable and efficacious protonophore that protects against diet‐induced obesity."

Axelrod CL, King WT, Davuluri G, Noland RC, Hall J, Hull M, Dantas WS, Zunica ER, Alexopoulos SJ, Hoehn KL, Langohr I, Stadler K, Doyle H, Schmidt E, Nieuwoudt S, Fitzgerald K, Pergola K, Fujioka H, Mey JT, Fealy C, Mulya A, Beyl R, Hoppel CL, Kirwan JP (2021) BAM15-mediated mitochondrial uncoupling protects against obesity and improves glycemic control. »Bioblast link«

from the O2k-Network »US LA Baton Rouge Noland RC« and »US OH Cleveland Hoppel CL«

Jun- 23 Fr

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

Jun- 24 Sa

Oroboros O2k-Workshop IOC Schroecken AT Jun 19-24

2023 Week 26

Jun- 26 Mo

Jun- 27 Tu

Jun- 28 We

Jun- 29 Th

Jun- 30 Fr

2023 Week 27

Jul- 03 Mo

Jul- 04 Tu

Jul- 05 We

Jul- 06 Th

Jul- 07 Fr

2023 Week 28

Jul- 10 Mo

Jul- 11 Tu

Jul- 12 We

Jul- 13 Th

Jul- 14 Fr

Jul- 15 Sa

»2nd Mitochondria Conference 2023 Lisbon PT« Jul 15-18

2023 Week 29

Jul- 17 Mo

»2nd Mitochondria Conference 2023 Lisbon PT« Jul 15-18

Jul- 18 Tu

Jul- 19 We

Jul- 20 Th

Jul- 21 Fr

Jul- 22 Sa

Jul- 23 Su

MiPschool Obergurgl 2023 Jul 23-27

2023 Week 30

Jul- 24 Mo

MiPschool Obergurgl 2023 Jul 23-27

Jul- 25 Tu

MiPschool Obergurgl 2023 Jul 23-27

Jul- 26 We

MiPschool Obergurgl 2023 Jul 23-27

Jul- 27 Th

MiPschool Obergurgl 2023 Jul 23-27

15^th MiPconference: Bioenergetics Communications on mitObesity Obergurgl 2023 Jul 27-30

Jul- 28 Fr

15^th MiPconference: Bioenergetics Communications on mitObesity Obergurgl 2023 Jul 27-30

Jul- 29 Sa

15^th MiPconference: Bioenergetics Communications on mitObesity Obergurgl 2023 Jul 27-30

Jul- 30 Su

15^th MiPconference: Bioenergetics Communications on mitObesity Obergurgl 2023 Jul 27-30

2023 Week 31

Jul- 31 Mo

Aug- 01 Tu

Aug- 02 We

Aug- 03 Th

Aug- 04 Fr

Aug- 05 Sa

Aug- 06 Su

2023 Week 32

Aug- 07 Mo

Aug- 08 Tu

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Aug- 11 Fr

2023 Week 33

Aug- 14 Mo

Aug- 15 Tu

Aug- 16 We

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Aug- 18 Fr

2023 Week 34

Aug- 21 Mo

Aug- 22 Tu

Aug- 23 We

Aug- 24 Th

Aug- 25 Fr

2023 Week 35

Aug- 28 Mo

Aug- 29 Tu

Aug- 30 We

Aug- 31 Th

Sep- 01 Fr

2023 Week 36

Sep- 04 Mo

Sep- 05 Tu

Sep- 06 We

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2023 Week 37

Sep- 11 Mo

Sep- 12 Tu

Sep- 13 We

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Sep- 15 Fr

2023 Week 38

Sep- 18 Mo

Sep- 19 Tu

Sep- 20 We

Sep- 21 Th

Sep- 22 Fr

2023 Week 39

Sep- 25 Mo

Sep- 26 Tu

Sep- 27 We

Sep- 28 Th

Sep- 29 Fr

2023 Week 40

Oct- 02 Mo