Beach 2013 Abstract MiP2013
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| Beach A, Richard VR, Leonov A, Burstein MT, Feldman R, Gentile C, Titorenko VI (2013) Lithocholic acid delays aging in yeast and exhibits an anti-tumor effect in human cells by altering mitochondrial composition, structure and function. Mitochondr Physiol Network 18.08. |
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Beach A, Richard VR, Leonov A, Burstein MT, Feldman R, Gentile C, Titorenko VI (2013)
Event: MiP2013
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Affiliations and author contributions
Dept of Biology, Concordia University, Montreal, Canada.
Email: adam.pb.beach@gmail.com
References
- Goldberg AA, Bourque SD, Kyryakov P, Gregg C, Boukh-Viner T, Beach A, Burstein MT, Machkalyan G, Richard V, Rampersad S, Cyr D, Milijevic S, Titorenko VI (2009) Effect of calorie restriction on the metabolic history of chronologically aging yeast. Exp Gerontol 44: 555-571.
- Goldberg AA, Richard VR, Kyryakov P, Bourque SD, Beach A, Burstein MT, Glebov A, Koupaki O, Boukh-Viner T, Gregg C, Juneau M, English AM, Thomas DY, Titorenko VI (2010) Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes. Aging 2: 393-414.
- Beach A, Titorenko VI (2011) In search of housekeeping pathways that regulate longevity. Cell Cycle 10: 3042-3044.
- Goldberg AA, Beach A, Davies GF, Harkness TAA, LeBlanc A, Titorenko VI (2011) Lithocholic bile acid selectively kills neuroblastoma cells, while sparing normal neuronal cells. Oncotarget 2:761-782.
- Kyryakov P, Beach A, Richard VR, Burstein MT, Leonov A, Levy S, Titorenko VI (2012) Caloric restriction extends yeast chronological lifespan by altering a pattern of age-related changes in trehalose concentration. Front Physiol 3: 256.
- Beach A, Burstein MT, Richard VR, Leonov A, Levy S, Titorenko VI (2012) Integration of peroxisomes into an endomembrane system that governs cellular aging. Front Physiol 3:283.
- Burstein MT, Kyryakov P, Beach A, Richard VR, Koupaki O, Gomez-Perez A, Leonov A, Levy S, Noohi F, Titorenko VI (2012) Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan. Cell Cycle 11:3443-3462.
- Beach A, Burstein MT, Richard VR, Gomez-Perez A, Leonov A, Iouk T, Titorenko VI (2013) A modular network regulates longevity of chronologically aging yeast. Cell Biol Res Ther 2: 1000e110.
