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Revision as of 00:49, 9 November 2020 by Gnaiger Erich (talk | contribs) (Gnaiger Erich moved page Free ET capacity to Net ET-capacity E-L)
Description
The free ET capacity, E-L, is the ET capacity corrected for LEAK respiration. E-L is the respiratory capacity potentially available for ion transport and phosphorylation of ADP to ATP. Oxygen consumption in the ET-pathway state, therefore, is partitioned into the free ET capacity, E-L, and LEAK respiration, LP, compensating for proton leaks, slip and cation cycling: E = E-L+LP (see free OXPHOS capacity).
Abbreviation: E-L
Reference: Gnaiger 2020 MitoPathways
Communicated by Gnaiger E (2014-09-21) last upate 2020-11-07.
Coupling control states for E-L
- Reference state, rate ZX: ET capacity; E = Eยด-Rox
- Background state, rate YX: LEAK respiration; L = Lยด-Rox
- Metabolic control variable, X=ZX-YX: Scope of uncoupler stimulation, Free ET capacity E-L
Flux control efficiency
- ยป Flux control efficiency, jZ-Y
- Coupling control efficiency, 1-YX/ZX: E-L coupling control efficiency, ET-coupling efficiency: jE-L = (E-L)/E = 1-L/E
Compare
- mt-Preparations Free OXPHOS capacity, P-L
- Intact cells Free ROUTINE activity, R-L