Juhasz 2017 MiPschool Obergurgl
From Bioblast
 Blockade of N-methyl-D-aspartate receptors improves polymicrobial sepsis-evoked mitochondrial dysfunction in rats. |
Link: MITOEAGLE
Juhasz L, Poles MZ, Tallosy SZP, Rutai A, Boros M, Vecsei L, Szabo A, Kaszaki J (2017)
Event: MiPschool Obergurgl 2017
At the request of the authors, this abstract is not made available online.
• Bioblast editor: Kandolf G
• O2k-Network Lab: HU Szeged Boros M
Labels: MiParea: Respiration Pathology: Other
Organism: Rat Tissue;cell: Liver Preparation: Homogenate
Regulation: Calcium Coupling state: LEAK, OXPHOS Pathway: N, S HRR: Oxygraph-2k
Affiliations
- Juhász L(1), Poles MZ(1), Tallósy SZP(1), Rutai A(1), Boros M(1), Vécsei L(2), Szabó A(1), Kaszaki J(1)
- Univ Szeged, Inst Surgical Research
- Univ Szeged, Dept Neurol.- jilajila@gmail.com
References and support
- Singer M (2014) The role of mitochondrial dysfunction in sepsis-induced multi-organ failure. Virulence 5:66-72.
- Duan Y, Gross RA, Sheu SS (2007) Ca2+-dependent generation of mitochondrial reactive oxygen species serves as a signal for poly(ADP-ribose) polymerase-1 activation during glutamate excitotoxicity. J Physiol 585:741-58.
- Pinto BB, Dyson A, Umbrello M, Carré JE, Ritter C, Clatworthy I, Duchen MR, Singer M (2017) Improved Survival in a long term-model of sepsis is associated with reduced mitochondrial calcium uptake despite increased energetic demand. Crit Care Med [Epub ahead of print]
- Financial support: NKFIH K116689, GINOP-2.3.2-15-2016-00034
Instructions
- All details: Abstracts
