Difference between revisions of "Respiratory acceptor control ratio"
Line 1: | Line 1: | ||
{{MitoPedia | {{MitoPedia | ||
|abbr=RCR | |abbr=RCR | ||
|description=The '''respiratory control ratio''' (RCR) is defined as [[State 3]]/[[State 4]] ([[Chance 1955 JBC-III|Chance and Williams 1955]]).Β Considering an index of [[uncoupling]], RCR should be replaced by the ''[[L/E]]'' ratio, if ''[[P/E]]''<1.0 ([[ | |description=The '''respiratory control ratio''' (RCR) is defined as [[State 3]]/[[State 4]] ([[Chance 1955 JBC-III|Chance and Williams 1955]]).Β Considering an index of [[uncoupling]], RCR should be replaced by the ''[[L/E]]'' ratio, if ''[[P/E]]''<1.0 ([[Gnaiger 2009 Int J Biochem Cell Biol|Gnaiger 2009]]).Β In intact cells, RCR has been used for the ratio [[State 3u]]/[[State 4o]], i.e. for the inverse ''L/E'' ratio ([[Hutter_2004_Biochem J|Huetter et al., 2004]]). | ||
|info=[[Chance 1955 JBC-III]]; [[MiPNet12.15]] | |info=[[Chance 1955 JBC-III]]; [[MiPNet12.15]] | ||
|type=Respiration | |type=Respiration |
Revision as of 19:04, 17 February 2012
- high-resolution terminology - matching measurements at high-resolution
Respiratory acceptor control ratio
Description
The respiratory control ratio (RCR) is defined as State 3/State 4 (Chance and Williams 1955). Considering an index of uncoupling, RCR should be replaced by the L/E ratio, if P/E<1.0 (Gnaiger 2009). In intact cells, RCR has been used for the ratio State 3u/State 4o, i.e. for the inverse L/E ratio (Huetter et al., 2004).
Abbreviation: RCR
Reference: Chance 1955 JBC-III; MiPNet12.15
MitoPedia methods:
Respirometry
MitoPedia topics: "Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Respiratory state"Respiratory state" is not in the list (Enzyme, Medium, Inhibitor, Substrate and metabolite, Uncoupler, Sample preparation, Permeabilization agent, EAGLE, MitoGlobal Organizations, MitoGlobal Centres, ...) of allowed values for the "MitoPedia topic" property.
Discussion
The RCR is discussed in the context of OXPHOS versus ETS capacity.