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From Bioblast
Year | Reference | Coupling | Pathways | Preparations | Species;model | Tissue;cell | |
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Jayakumari 2020 J Diabetes | 2020 | Jayakumari NR, Rajendran RS, Sivasailam A, Vimala SS, Nanda S, Manjunatha S, Pillai VV, Karunakaran J, Gopala S (2020) Impaired substrate-mediated cardiac mitochondrial complex I respiration with unaltered regulation of fatty acid metabolism and oxidative stress status in type 2 diabetic Asian Indians. J Diabetes 12:542-55. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Human | Heart |
Karabatsiakis 2020 Transl Psychiatry | 2020 | Karabatsiakis DA, Schönfeldt-Lecuona PDC (2020) Depression, mitochondrial bioenergetics, and electroconvulsive therapy: a new approach towards personalized medicine in psychiatric treatment - a short review and current perspective. Transl Psychiatry 10:226. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Deleye 2020 J Biol Chem | 2020 | Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R (2020) CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway. J Biol Chem 295:17310-22. | LEAK OXPHOS | F N | Homogenate | Mouse | Liver |
Yurre 2020 Arq Bras Cardiol | 2020 | Yurre AR, Silva JDFD, Torres MKDS, Martins EL, Ramos IP, Silva WSFLD, Sarpa JDS, Guedes CCDS, Napoleão TH, Coelho LCBB, Paiva PMG, Medei E (2020) Evaluation of the cardiac effects of a water-soluble lectin (Wsmol) from Moringa oleifera seeds. Arq Bras Cardiol 114:1029-37. | LEAK OXPHOS | N NS ROX | Isolated mitochondria | Mouse | Heart |
Fuchs 2020 J Funct Foods | 2020 | Fuchs C, Bakuradze T, Steinke R, Grewal R, Eckert GP, Richling E (2020) Polyphenolic composition of extracts from winery by-products and effects on cellular cytotoxicity and mitochondrial functions in HepG2 cells. J Funct Foods 70:103988. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Liver |
Belosludtsev 2020 Biochimie | 2020 | Belosludtsev KN, Belosludtseva NV, Kosareva EA, Talanov EY, Gudkov SV, Dubinin MV (2020) Itaconic acid impairs the mitochondrial function by the inhibition of complexes II and IV and induction of the permeability transition pore opening in rat liver mitochondria. Biochimie 176:150-57. | LEAK OXPHOS | N S CIV | Isolated mitochondria | Rat | Liver |
Kunz 2020 J Biol Chem | 2020 | Kunz HE, Dorschner JM, Berent TE, Meyer T, Wang X, Jatoi A, Kumar R, Lanza IR (2020) Methylarginine metabolites are associated with attenuated muscle protein synthesis in cancer-associated muscle wasting. J Biol Chem 295:17441-59. | LEAK ROUTINE OXPHOS ET | N NS ROX S | Permeabilized tissue Intact cells | Mouse | Skeletal muscle |
Dawson 2020 J Exp Biol | 2020 | Dawson NJ, Millet C, Selman C, Metcalfe NB (2020) Measurement of mitochondrial respiration in permeabilized fish gills. J Exp Biol 223:jeb216762. | LEAK OXPHOS | N CIV NS ROX | Permeabilized tissue | Fishes | Lung;gill |
Rebane-Klemm 2020 Cancers (Basel) | 2020 | Rebane-Klemm E, Truu L, Reinsalu L, Puurand M, Shevchuk I, Chekulayev V, Timohhina N, Tepp K, Bogovskaja J, Afanasjev V, Suurmaa K, Valvere V, Kaambre T (2020) Mitochondrial respiration in KRAS and BRAF mutated colorectal tumors and polyps. Cancers (Basel) 12:E815. | LEAK OXPHOS | N NS | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Mahul-Mellier 2020 Proc Natl Acad Sci U S A | 2020 | Mahul-Mellier AL, Burtscher J, Maharjan N, Weerens L, Croisier M, Kuttler F, Leleu M, Knott GW, Lashuel HA (2020) The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration. Proc Natl Acad Sci U S A 117:4971-82. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Mouse | Nervous system |
Truong 2020 Cytokine | 2020 | Truong NTT, Lydic TA, Bazil JN, Suryadevara A, Olson LK (2020) Regulation of lipid metabolism in pancreatic beta cells by interferon gamma: a link to anti-viral function. Cytokine 133:155147. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Hoffmann 2020 J Clin Endocrinol Metab | 2020 | Hoffmann C, Schneeweiss P, Randrianarisoa E, Schnauder G, Kappler L, Machann J, Schick F, Fritsche A, Heni M, Birkenfeld A, Niess AM, Häring HU, Weigert C, Moller A (2020) Response of mitochondrial respiration in adipose tissue and muscle to 8 weeks of endurance exercise in obese subjects. J Clin Endocrinol Metab 105:dgaa571. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle Fat |
Alston 2020 Am J Hum Genet | 2020 | Alston CL, Veling MT, Heidler J, Taylor LS, Alaimo JT, Sung AY, He L, Hopton S, Broomfield A, Pavaine J, Diaz J, Leon E, Wolf P, McFarland R, Prokisch H, Wortmann SB, Bonnen PE, Wittig I, Pagliarini DJ, Taylor RW (2020) Pathogenic bi-allelic mutations in NDUFAF8 cause Leigh syndrome with an isolated complex I deficiency. Am J Hum Genet 106:92-101. | LEAK ROUTINE OXPHOS ET | N NS | Permeabilized cells Intact cells | Human | Fibroblast |
Cornelissen 2020 Hum Mol Genet | 2020 | Cornelissen T, Spinazzi M, Martin S, Imberechts D, Vangheluwe P, Bird M, De Strooper B, Vandenberghe W (2020) CHCHD2 harboring the Parkinson's disease-linked T61I mutation precipitates inside mitochondria and induces precipitation of wild-type CHCHD2. Hum Mol Genet 29:1096-106. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized cells | Human | Fibroblast |
Li Puma 2020 Am J Physiol Regul Integr Comp Physiol | 2020 | Li Puma LC, Hedges M, Heckman JM, Mathias AB, Engstrom MR, Brown AB, Chicco AJ (2020) Experimental oxygen concentration influences rates of mitochondrial hydrogen peroxide release from cardiac and skeletal muscle preparations. Am J Physiol Regul Integr Comp Physiol 318:972-80. | LEAK OXPHOS | N NS | Permeabilized tissue Homogenate Isolated mitochondria | Mouse | Heart Skeletal muscle |
Severo 2020 Life Sci | 2020 | Severo L, Godinho D, Machado F, Hartmann D, Fighera MR, Soares FA, Furian AF, Oliveira MS, Royes LF (2020) The role of mitochondrial bioenergetics and oxidative stress in depressive behavior in recurrent concussion model in mice. Life Sci 257:117991. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Weaver 2020 Biol Lett | 2020 | Weaver RJ, Carrion G, Nix R, Maeda GP, Rabinowitz S, Iverson ENK, Thueson K, Havird JC (2020) High mitochondrial mutation rates in Silene are associated with nuclear-mediated changes in mitochondrial physiology. Biol Lett 16:20200450. | LEAK OXPHOS | N S CIV NS | Isolated mitochondria | Plants | |
MitoEAGLE muscle 1 | 2020 | Doerrier C, Gama-Perez P, Distefano G, Pesta D, Soendergaard SD, Chroeis KM, Gonzalez-Franquesa A, Goodpaster BH, Coen P, Larsen S, Gnaiger E, Garcia-Roves PM (2020) Inter-laboratory harmonization of respiratory protocols in permeabilized human muscle fibers. - Updated: 2020-03-08 | LEAK OXPHOS ET | N NS S ROX | Permeabilized tissue | Human | Skeletal muscle |
Schoepf 2020 Nat Commun | 2020 | Schöpf Bernd, Weissensteiner Hansi, Schäfer Georg, Fazzini Federica, Charoentong Pornpimol, Naschberger Andreas, Rupp Bernhard, Fendt Liane, Bukur Valesca, Giese Irina, Sorn Patrick, Sant’Anna-Silva Ana Carolina, Iglesias-Gonzalez Javier, Sahin Ugur, Kronenberg Florian, Gnaiger Erich, Klocker Helmut (2020) OXPHOS remodeling in high-grade prostate cancer involves mtDNA mutations and increased succinate oxidation. https://doi.org/10.1038/s41467-020-15237-5 | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Permeabilized tissue | Human | Genital Other cell lines |
Lozano 2020 Part Fibre Toxicol | 2020 | Lozano O, Silva-Platas C, Chapoy-Villanueva H, Pérez BE, Lees JG, Ramachandra CJA, Contreras-Torres FF, Lázaro-Alfaro A, Luna-Figueroa E, Bernal-Ramírez J, Gordillo-Galeano A, Benitez A, Oropeza-Almazán Y, Castillo EC, Koh PL, Hausenloy DJ, Lim SY, García-Rivas G (2020) Amorphous SiO2 nanoparticles promote cardiac dysfunction via the opening of the mitochondrial permeability transition pore in rat heart and human cardiomyocytes. Part Fibre Toxicol 17:15. | LEAK OXPHOS ET | S | Isolated mitochondria | Rat Human | Heart |
Allen 2020 Commun Biol | 2020 | Allen ME, Pennington ER, Perry JB, Dadoo S, Makrecka-Kuka M, Dambrova M, Moukdar F, Patel HD, Han X, Kidd GK, Benson EK, Raisch TB, Poelzing S, Brown DA, Shaikh SR (2020) The cardiolipin-binding peptide elamipretide mitigates fragmentation of cristae networks following cardiac ischemia reperfusion in rats. Commun Biol 3:389. | LEAK OXPHOS ET | N S CIV | Permeabilized tissue | Rat | Heart |
Garcia 2020 Mol Hum Reprod | 2020 | Garcia BM, Machado TS, Carvalho KF, Nolasco P, Nociti RP, Del Collado M, Capo Bianco MJD, Grejo MP, Neto JDA, Sugiyama FHC, Tostes K, Pandey AK, Gonçalves LM, Perecin F, Meirelles FV, Ferraz JBS, Vanzela EC, Boschero AC, Guimarães FEG, Abdulkader F, Laurindo FRM, Kowaltowski AJ, Chiaratti MR (2020) Mice born to females with oocyte-specific deletion of mitofusin 2 have increased weight gain and impaired glucose homeostasis. Mol Hum Reprod 26:938-52. | LEAK OXPHOS ET | S | Isolated mitochondria | Mouse | Liver |
Kahancova 2020 Sci Rep | 2020 | Kahancová A, Sklenář F, Ježek P, Dlasková A (2020) Overexpression of native IF1 downregulates glucose-stimulated insulin secretion by pancreatic INS-1E cells. Sci Rep 10:1551. | LEAK ROUTINE ET | Intact cells | Rat | Islet cell;pancreas;thymus | |
Maeda 2020 J Cell Mol Med | 2020 | Maeda H, Kami D, Maeda R, Murata Y, Jo JI, Kitani T, Tabata Y, Matoba S, Gojo S (2020) TAT-dextran-mediated mitochondrial transfer enhances recovery from models of reperfusion injury in cultured cardiomyocytes. J Cell Mol Med 24:5007-20. | LEAK ROUTINE OXPHOS ET | N ROX | Isolated mitochondria Intact cells | Rat | Heart |
Fecker 2020 Biomolecules | 2020 | Fecker R, Buda V, Alexa E, Avram S, Pavel IZ, Muntean D, Cocan I, Watz C, Minda D, Dehelean CA, Soica C, Danciu C (2020) Phytochemical and biological screening of Oenothera biennis L. hydroalcoholic extract. Biomolecules 10:E818. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Boardman 2020 Am J Physiol Heart Circ Physiol | 2020 | Boardman NT, Pedersen TM, Rossvoll L, Hafstad AD, Aasum E (2020) Diet-induced obese mouse hearts tolerate an acute high fatty acid exposure that also increases ischemic tolerance. Am J Physiol Heart Circ Physiol 319:H682-93. | LEAK OXPHOS | F N | Isolated mitochondria | Mouse | Heart |
Woessner 2020 Thesis | 2020 | Woessner MN (2020) BEET-HF: The effects of dietary inorganic nitrate supplementation on aerobic exercise performance, vascular function, cardiac performance and mitochondrial respiration in patients with heart failure with reduced ejection fraction. PhD Thesis 198. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Ost 2020 EMBO Rep | 2020 | Ost M, Igual Gil C, Coleman V, Keipert S, Efstathiou S, Vidic V, Weyers M, Klaus S (2020) Muscle-derived GDF15 drives diurnal anorexia and systemic metabolic remodeling during mitochondrial stress. EMBO Rep 21:e48804. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Juarez-Flores 2020 Antioxidants (Basel) | 2020 | Juarez-Flores DL, Ezquerra M, Gonzalez-Casacuberta I, Ormazabal A, Moren C, Tolosa E, Fucho R, Guitart-Mampel M, Casado M, Valldeoriola F, de la Torre-Lara J, Munoz E, Tobias E, Compta Y, Garcia-Garcia FJ, Garcia-Ruiz C, Fernandez-Checa JC, Marti MJ, Grau JM, Cardellach F, Artuch R, Fernandez-Santiago R, Garrabou G (2020) Disrupted mitochondrial and metabolic plasticity underlie comorbidity between age-related and degenerative disorders as Parkinson disease and type 2 diabetes mellitus. Antioxidants (Basel) 9:1063. | LEAK ROUTINE ET | ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Venediktova 2020 Mitochondrion | 2020 | Venediktova NI, Mashchenko OV, Talanov EY, Belosludtseva NV, Mironova GD (2020) Energy metabolism and oxidative status of rat liver mitochondria in conditions of experimentally induced hyperthyroidism. Mitochondrion 52:190-96. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Liver |
Politis-Barber 2020 Am J Physiol Endocrinol Metab | 2020 | Politis-Barber V, Brunetta HS, Paglialunga S, Petrick HL, Holloway GP (2020) Long-term high-fat feeding exacerbates short-term increases in adipose mitochondrial reactive oxygen species, without impairing mitochondrial respiration. Am J Physiol Endocrinol Metab 319:E376-87. | LEAK OXPHOS | F N Gp NS | Permeabilized cells | Mouse | Fat |
Bundgaard 2020 J Exp Biol | 2020 | Bundgaard A, Qvortrup K, Rasmussen LJ, Fago A (2020) Turtles maintain mitochondrial integrity but reduce mitochondrial respiratory capacity in the heart after cold acclimation and anoxia. J Exp Biol 222:jeb200410. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Amphibians | Heart |
Zussman 2020 J Autoimmun | 2020 | Zussman R, Xu LY, Damani T, Groom KM, Chen Q, Seers B, Viall CA, Chamley LW, Hickey A (2020) Antiphospholipid antibodies can specifically target placental mitochondria and induce ROS production. J Autoimmun 111:102437. | LEAK ET | N S Gp CIV NS ROX | Permeabilized tissue | Human | Genital |
Gutierrez 2020 Sci Signal | 2020 | Gutiérrez T, Qi H, Yap MC, Tahbaz N, Milburn LA, Lucchinetti E, Lou PH, Zaugg M, LaPointe PG, Mercier P, Overduin M, Bischof H, Burgstaller S, Malli R, Ballanyi K, Shuai J, Simmen T (2020) The ER chaperone calnexin controls mitochondrial positioning and respiration . Sci Signal 13:eaax6660. | LEAK ROUTINE ET | Intact cells | Mouse | Fibroblast | |
Gumpp 2020 Proc Natl Acad Sci U S A | 2020 | Gumpp AM, Boeck C, Behnke A, Bach AM, Ramo-Fernández L, Welz T, Gündel H, Kolassa IT, Karabatsiakis A (2020) Childhood maltreatment is associated with changes in mitochondrial bioenergetics in maternal, but not in neonatal immune cells. Proc Natl Acad Sci U S A 117:24778-84. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Xia 2020 Biomed Res Int | 2020 | Xia W, Wang Q, Lu Y, Hu Y, Zhang X, Zhang J, Liu D, Song J, Zhu Z, Liu D, Zhang H (2020) Transient receptor potential channel canonical type 3 deficiency antagonizes myofibroblast transdifferentiation in vivo. Biomed Res Int 2020:1202189. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Peres de Oliveira 2020 Proteome Sci | 2020 | Peres de Oliveira A, Basei FL, Slepicka PF, de Castro Ferezin C, Melo-Hanchuk TD, de Souza EE, Lima TI, Dos Santos VT, Mendes D, Silveira LR, Menck CFM, Kobarg J (2020) NEK10 interactome and depletion reveal new roles in mitochondria. Proteome Sci 18:4. | LEAK ROUTINE ET | Intact cells | Human | HeLa | |
Cruz 2020 Cancers (Basel) | 2020 | Cruz B, Oliveira A, Viana LR, Lopes-Aguiar L, Canevarolo R, Colombera MC, Valentim RR, Garcia-Fóssa F, de Sousa LM, Castelucci BG, Consonni SR, Martins-de-Souza D, de Jesus MB, Russell ST, Gomes-Mardondes MCC (2020) Leucine-tich diet modulates the metabolomic and proteomic profile of skeletal muscle during cancer cachexia. Cancers (Basel) 12:E1880. | LEAK ROUTINE ET | Intact cells | Mouse | Skeletal muscle | |
Lensu 2020 Nutrients | 2020 | Lensu S, Pariyani R, Mäkinen E, Yang B, Saleem W, Munukka E, Lehti M, Driuchina A, Lindén J, Tiirola M, Lahti L, Pekkala S (2020) Prebiotic xylo-oligosaccharides ameliorate high-fat-diet-induced hepatic steatosis in rats . Nutrients 12:E3225. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Rat | Liver |
Tepp 2020 Biochim Biophys Acta Gen Subj | 2020 | Tepp K, Puurand M, Timohhina N, Aid-Vanakova J, Reile I, Shevchuk I, Chekulayev V, Eimre M, Peet N, Kadaja L, Paju K, Kaambre T (2020) Adaptation of striated muscles to Wolframin deficiency in mice: Alterations in cellular bioenergetics. Biochim Biophys Acta Gen Subj 1864:129523. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Mouse | Heart Skeletal muscle |
Xiong 2020 Biomed Pharmacother | 2020 | Xiong Xiaowei, Lu Weihang, Qin Xuan, Luo Qingyu, Zhou Weimin (2020) Downregulation of the GLP-1/CREB/adiponectin pathway is partially responsible for diabetes-induced dysregulated vascular tone and VSMC dysfunction. Biomed Pharmacother 127:110218. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Human Rat | Endothelial;epithelial;mesothelial cell |
Smith 2020 J Biol Chem | 2020 | Smith CD, Schmidt CA, Lin CT, Fisher-Wellman KH, Neufer PD (2020) Flux through mitochondrial redox circuits linked to nicotinamide nucleotide transhydrogenase generates counterbalance changes in energy expenditure. J Biol Chem 295:16207-16. | LEAK OXPHOS ET | F N | Isolated mitochondria | Mouse | Skeletal muscle |
Rodriguez 2020 J Gerontol A Biol Sci Med Sci | 2020 | Rodríguez E, Hakkou M, Hagen TM, Lemieux H, Blier PU (2020) Divergences in the control of mitochondrial respiration are associated with lifespan variation in marine bivalves. J Gerontol A Biol Sci Med Sci 76:796-804. | LEAK OXPHOS ET | F N S Gp CIV ROX | Isolated mitochondria | Molluscs | |
No 2020 Pflugers Arch | 2020 | No MH, Heo JW, Yoo SZ, Kim CJ, Park DH, Kang JH, Seo DY, Han J, Kwak HB (2020) Effects of aging and exercise training on mitochondrial function and apoptosis in the rat heart. Pflugers Arch 472:179-93. | LEAK OXPHOS | N NS | Permeabilized tissue | Rat | Heart |
Dolezelova 2020 PLoS Biol | 2020 | Doleželová E, Kunzová M, Dejung M, Levin M, Panicucci B, Regnault C, Janzen CJ, Barrett MP, Butter F, Zíková A (2020) Cell-based and multi-omics profiling reveals dynamic metabolic repurposing of mitochondria to drive developmental progression of Trypanosoma brucei. PLoS Biol 18:e3000741. | LEAK ROUTINE | S Gp CIV | Permeabilized cells Intact cells | Protists | |
D'Urso 2020 Surg Endosc | 2020 | D'Urso A, Agnus V, Barberio M, Seeliger B, Marchegiani F, Charles AL, Geny B, Marescaux J, Mutter D, Diana M (2020) Computer-assisted quantification and visualization of bowel perfusion using fluorescence-based enhanced reality in left-sided colonic resections. Surg Endosc 35:4321-31. | LEAK OXPHOS | N NS | Human | Endothelial;epithelial;mesothelial cell | |
Boehmert 2020 Transfusion | 2020 | Böhmert S, Kübel S, Müller MM, Weber CF, Adam EH, Dröse S, Zacharowski K, Fischer D (2020) The effect of the interruption of agitation, temporary cooling, and pneumatic tube transportation on platelet quality during storage for transfusion. Transfusion 61:1258-65. | LEAK ROUTINE ET | CIV | Intact cells | Human | Platelet |
Locatelli 2020 FASEB J | 2020 | Locatelli L, Cazzaniga A, De Palma C, Castiglioni S, Maier JAM (2020) Mitophagy contributes to endothelial adaptation to simulated microgravity. FASEB J 34:1833-45. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Mohsin 2020 Arch Biochem Biophys | 2020 | Mohsin AA, Thompson J, Hu Y, Hollander J, Lesnefsky EJ, Chen Q (2020) Endoplasmic reticulum stress-induced complex I defect: Central role of calcium overload. Arch Biochem Biophys 683:108299. | LEAK OXPHOS | N S | Permeabilized cells | Rat | Skeletal muscle |
Ulgherait 2020 Nat Commun | 2020 | Ulgherait Matt, Chen Anna, McAllister Sophie F, Kim Han X, Delventhal Rebecca, Wayne Charlotte R, Garcia Christian J, Recinos Yocelyn, Oliva Miles, Canman Julie C, Picard Martin, Owusu-Ansah Edward, Shirasu-Hiza Mimi (2020) Circadian regulation of mitochondrial uncoupling and lifespan. Nat Commun 11:1927. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Drosophila | |
Irion 2020 Stem Cells Int | 2020 | Irion CI, Martins EL, Christie MLA, de Andrade CBV, de Moraes ACN, Ferreira RP, Pimentel CF, Suhett GD, Campos de Carvalho AC, Lindoso RS, Vieyra A, Galina A, Goldenberg RCS (2020) Acute myocardial infarction reduces respiration in rat cardiac fibers, despite adipose tissue mesenchymal stromal cell transplant. Stem Cells Int 2020:4327965 . | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Heart |
Song 2020 Obes Facts | 2020 | Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) Increased insulin sensitivity by high-altitude hypoxia in mice with high-fat diet-induced obesity is associated with activated AMPK signaling and subsequently enhanced mitochondrial biogenesis in skeletal muscles. Obes Facts 13:455-72. | LEAK OXPHOS | F N | Permeabilized tissue | Skeletal muscle | |
Protasoni 2020 EMBO J | 2020 | Protasoni M, Pérez-Pérez R, Lobo-Jarne T, Harbour ME, Ding S, Peñas A, Diaz F, Moraes CT, Fearnley IM, Zeviani M, Ugalde C, Fernández-Vizarra E (2020) Respiratory supercomplexes act as a platform for complex III-mediated maturation of human mitochondrial complexes I and IV. EMBO J 39:e102817. | LEAK ROUTINE ET | ROX | Intact cells | Human | Other cell lines |
Wefers 2020 Mol Metab | 2020 | Wefers J, Connell NJ, Fealy CE, Andriessen C, de Wit V, van Moorsel D, Moonen-Kornips E, Jörgensen JA, Hesselink MKC, Havekes B, Hoeks J, Schrauwen P (2020) Day-night rhythm of skeletal muscle metabolism is disturbed in older, metabolically compromised individuals. Mol Metab 41:101050. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Kamarauskaite 2020 Biomed Res Int | 2020 | Kamarauskaite J, Baniene R, Trumbeckas D, Strazdauskas A, Trumbeckaite S (2020) Increased succinate accumulation induces ROS generation in in vivo ischemia/reperfusion-affected rat kidney mitochondria. Biomed Res Int 2020:8855585. | LEAK OXPHOS | N S | Rat | Kidney | |
Purhonen 2020 Nat Commun | 2020 | Purhonen J, Grigorjev V, Ekiert R, Aho N, Rajendran J, Pietras R, Truvé K, Wikström M, Sharma V, Osyczka A, Fellman V, Kallijärvi J (2020) A spontaneous mitonuclear epistasis converging on Rieske Fe-S protein exacerbates complex III deficiency in mice. Nat Commun 11:322. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Liver Kidney |
Baggio 2020 Neurotoxicology | 2020 | Baggio S, Zenki K, Martins Silva A, Dos Santos TG, Rech G, Lazzarotto G, Dias RD, Mussulini BH, Rico EP, de Oliveira DL (2020) Fetal alcohol spectrum disorders model alters the functionality of glutamatergic neurotransmission in adult zebrafish. Neurotoxicology 78:152-160. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Zebrafish | Nervous system |
Pelster 2020 PLoS One | 2020 | Pelster B, Wood CM, Campos DF, Val AL (2020) Cellular oxygen consumption, ROS production and ROS defense in two different size-classes of an Amazonian obligate air-breathing fish (Arapaima gigas). PLoS One 15:e0236507. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Fishes | Kidney Lung;gill |
Contreras Mostazo 2020 Cancers (Basel) | 2020 | Mostazo MGC, Kurrle N, Casado M, Fuhrmann D, Alshamleh I, Häupl B, Martín-Sanz P, Brüne B, Serve H, Schwalbe H, Schnütgen F, Marin S, Cascante M (2020) Metabolic plasticity is an essential requirement of acquired tyrosine kinase inhibitor resistance in chronic myeloid leukemia. Cancers (Basel) 12:E3443. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV ROX | Permeabilized cells Intact cells | Human | Blood cells |
Kanellopoulos 2020 Cell | 2020 | Kanellopoulos AK, Mariano V, Spinazzi M, Woo YJ, McLean C, Pech U, Li KW, Armstrong JD, Giangrande A, Callaerts P, Smit AB, Abrahams BS, Fiala A, Achsel T, Bagni C (2020) Aralar sequesters GABA into hyperactive mitochondria, causing social behavior deficits. Cell 180:1178-97. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Drosophila | Nervous system Other cell lines |
Burtscher 2020 Int J Mol Sci | 2020 | Burtscher J, Di Pardo A, Maglione V, Schwarzer C, Squitieri F (2020) Mitochondrial respiration changes in R6/2 Huntington's Disease model mice during aging in a brain region specific manner. Int J Mol Sci 21:5412. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Mouse | Nervous system |
Luevano-Martinez 2020 FEBS Lett | 2020 | Luévano-Martínez LA, Girard RMBM, Alencar MB, Silber AM (2020) ATP regulates the activity of an alternative oxidase in Trypanosoma brucei. FEBS Lett [Epub ahead of print]. | LEAK ROUTINE ET | Intact cells | Protists | ||
Chang 2020 J Biol Chem | 2020 | Chang L, Liu X, Diggle CP, Boyle JP, Hopkins PM, Shaw MA, Allen PD (2020) Bioenergetic defects in muscle fibers of RYR1 mutant knock-in mice associated with malignant hyperthermia. J Biol Chem 295:15226-35. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Doig 2020 Skelet Muscle | 2020 | Doig CL, Zielinska AE, Fletcher RS, Oakey LA, Elhassan YS, Garten A, Cartwright D, Heising S, Alsheri A, Watson DG, Prehn C, Adamski J, Tennant DA, Lavery GG (2020) Induction of the nicotinamide riboside kinase NAD+ salvage pathway in a model of sarcoplasmic reticulum dysfunction. Skelet Muscle 10:5. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Carvalho 2020 BMC Nutr | 2020 | Carvalho E, Adams SH, Borsheim E, Blackburn ML, Ono-Moore KD, Cotter M, Bowlin AK, Yeruva L (2020) Neonatal diet impacts liver mitochondrial bioenergetics in piglets fed formula or human milk. BMC Nutr 6:13. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Pig | Liver |
Kuzniewska 2020 EMBO Rep | 2020 | Kuzniewska B, Cysewski D, Wasilewski M, Sakowska P, Milek J, Kulinski TM, Winiarski M, Kozielewicz P, Knapska E, Dadlez M, Chacinska A, Dziembowski A, Dziembowska M (2020) Mitochondrial protein biogenesis in the synapse is supported by local translation. EMBO Rep 21:e48882. | LEAK ET | N S | Permeabilized cells | Human Mouse | Nervous system HEK |
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Khamoui 2020 Physiol Genomics | 2020 | Khamoui AV, Tokmina-Roszyk D, Rossiter HB, Fields GB, Visavadiya NP (2020) Hepatic proteome analysis reveals altered mitochondrial metabolism and suppressed acyl-CoA synthetase-1 in colon-26 tumor-induced cachexia. Physiol Genomics 52:203-16. | LEAK OXPHOS ET | N NS | Intact cells | Mouse | Liver |
Seo 2020 J Clin Med | 2020 | Seo DY, Heo JW, No MH, Yoo SZ, Ko JR, Park DH, Kang JH, Kim CJ, Jung SJ, Han J, Kwak HB (2020) Exercise training protects against atorvastatin-induced skeletal muscle dysfunction and mitochondrial dysfunction in the skeletal muscle of rats. J Clin Med 9:E2292. | LEAK OXPHOS | N | Permeabilized tissue | Rat | Skeletal muscle |
Risiglione 2020 Int J Mol Sci | 2020 | Risiglione P, Leggio L, Cubisino SAM, Reina S, Paternò G, Marchetti B, Magrì A, Iraci N, Messina A (2020) High-resolution respirometry reveals MPP+ mitochondrial toxicity mechanism in a cellular model of parkinson's disease. Int J Mol Sci 21:E7809. https://doi.org/10.3390/ijms21217809 | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Intact cells | Human | Neuroblastoma |
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Pham 2020 Eur J Appl Physiol | 2020 | Pham T, MacRae CL, Broome SC, D'souza RF, Narang R, Wang HW, Mori TA, Hickey AJR, Mitchell CJ, Merry TL (2020) MitoQ and CoQ10 supplementation mildly suppresses skeletal muscle mitochondrial hydrogen peroxide levels without impacting mitochondrial function in middle-aged men. Eur J Appl Physiol 120:1657-69. | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Guo 2020 Hum Gene Ther | 2020 | Guo Y, Zhang K, Gao X, Zhou Z, Liu Z, Yang K, Huang K, Yang Q, Long Q (2020) Sustained oligomycin sensitivity conferring protein expression in cardiomyocytes protects against cardiac hypertrophy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89. | LEAK OXPHOS ET | N NS ROX | Isolated mitochondria | Mouse | Heart |
Thome 2020 JCI Insight | 2020 | Thome T, Kumar RA, Burke SK, Khattri RB, Salyers ZR, Kelley RC, Coleman MD, Christou DD, Hepple RT, Scali ST, Ferreira LF, Ryan TE (2020) Impaired muscle mitochondrial energetics is associated with uremic metabolite accumulation in chronic kidney disease. JCI Insight 6:e139826. | LEAK OXPHOS | F N S | Isolated mitochondria | Mouse | Skeletal muscle |
Madeo 2020 US Patent | 2020 | Madeo F, Eisenberg T, Stekovic S (2020) Use of spermidine for the enhancement of mitochondrial respiration. US Patent US20200054579 A1. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Heart |
Stankova 2020 Int J Mol Sci | 2020 | Staňková P, Kučera O, Peterová E, Lotková H, Maseko TE, Nožičková K, Červinková Z (2020) Adaptation of mitochondrial substrate flux in a mouse model of nonalcoholic fatty liver disease. Int J Mol Sci 21:E1101. | LEAK OXPHOS | F N S Gp NS ROX | Homogenate | Mouse | Liver |
Song 2020 Life Sci | 2020 | Song K, Zhang Y, Ga Q, Bai Z, Ge RL (2020) High-altitude chronic hypoxia ameliorates obesity-induced non-alcoholic fatty liver disease in mice by regulating mitochondrial and AMPK signaling. Life Sci 252:117633. | LEAK OXPHOS ET | F N NS | Homogenate | Mouse | Liver |
Falcao-Tebas 2020 J Physiol | 2020 | Falcão-Tebas F, Marin EC, Kuang J, Bishop DJ, McConell GK (2020) Maternal exercise attenuates the lower skeletal muscle glucose uptake and insulin secretion caused by paternal obesity in female adult rat offspring. J Physiol 598:4251-70. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Russell 2020 Nutrients | 2020 | Russell JS, Griffith TA, Naghipour S, Vider J, Du Toit EF, Patel HH, Peart JN, Headrick JP (2020) Dietary α-linolenic acid counters cardioprotective dysfunction in diabetic mice: unconventional PUFA protection. Nutrients 12:E2679. | LEAK OXPHOS ET | N S NS | Homogenate | Mouse | Heart |
Peruzzotti-Jametti 2020 bioRxiv | 2020 | Peruzzotti-Jametti L, Bernstock JD, Manferrari G, Rogall R, Fernandez-Vizarra E, Williamson JC, Braga A, van den Bosch A, Leonardi T, Kittel A, Benincá C, Vicario N, Tan S, Bastos C, Bicci I, Iraci N, Smith JA, Lehner PJ, Buzas EI, Faria N, Zeviani M, Frezza C, Brisson A, Matheson NJ, Viscomi C, Pluchino S (2020) Neural stem cells traffic functional mitochondria via extracellular vesicles to correct mitochondrial dysfunction in target cells. bioRxiv doi: https://doi.org/10.1101/2020.01.29.923441 . | LEAK | N S Gp CIV ROX | Permeabilized cells | Mouse | Stem cells |
Feng 2020 Int J Biol Macromol | 2020 | Feng Q, Shao M, Han J, Tang T, Zhang Y, Liu F (2020) TFAM, a potential oxidative stress biomarker used for monitoring environment pollutants in Musca domestica. Int J Biol Macromol 155:524-34. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Hexapods | |
Macedo 2020 FASEB J | 2020 | Macedo F, Romanatto T, Gomes de Assis C, Buis A, Kowaltowski AJ, Aguilaniu H, Marques da Cunha F (2020) Lifespan-extending interventions enhance lipid-supported mitochondrial respiration in Caenorhabditis elegans. FASEB J 34:9972-81. | LEAK OXPHOS | F N CIV ROX | Intact organism Isolated mitochondria | Caenorhabditis elegans | |
Avila-Rojas 2020 Food Chem Toxicol | 2020 | Avila-Rojas SH, Aparicio-Trejo OE, Briones-Herrera A, Medina-Campos ON, Reyes-Fermín LM, Martínez-Klimova E, León-Contreras JC, Hernández-Pando R, Tapia E, Pedraza-Chaverri J (2020) Alterations in mitochondrial homeostasis in a potassium dichromate model of acute kidney injury and their mitigation by curcumin. Food Chem Toxicol 145:111774. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Kidney |
Zhang 2020 Chemosphere | 2020 | Zhang Y, Li Y, Feng Q, Shao M, Yuan F, Liu F (2020) Polydatin attenuates cadmium-induced oxidative stress via stimulating SOD activity and regulating mitochondrial function in Musca domestica larvae. Chemosphere 248:126009. | LEAK OXPHOS | N S ROX | Isolated mitochondria | Hexapods | |
Davidson 2020 Circ Res | 2020 | Davidson MT, Grimsrud P, Lai L, Draper J, Fisher-Wellman KH, Narowski TM, Koves TR, Kelly DP, Muoio DM (2020) Extreme acetylation of the cardiac mitochondrial proteome does not promote heart failure. Circ Res 127:1094-108. | LEAK | F N | Isolated mitochondria | Mouse | Heart |
Dymkowska 2020 J Appl Toxicol | 2020 | Dymkowska D, Wrzosek A, Zabłocki K (2020) Atorvastatin and pravastatin stimulate nitric oxide and reactive oxygen species generation, affect mitochondrial network architecture and elevate nicotinamide N-methyltransferase level in endothelial cells. J Appl Toxicol 41:1076-88. | LEAK ET ROUTINE | Intact cells | Human | Endothelial;epithelial;mesothelial cell | |
Friederich-Persson 2020 Am J Physiol Renal Physiol | 2020 | Friederich-Persson M, Persson P (2020) Mitochondrial angiotensin II receptors regulate oxygen consumption in kidney mitochondria from healthy and type 1 diabetic rats. Am J Physiol Renal Physiol 318:F683-88. | LEAK OXPHOS | N Gp | Isolated mitochondria | Rat | Kidney |
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Herpich 2020 Exp Gerontol | 2020 | Herpich C, Franz K, Klaus S, Müller-Werdan U, Ost M, Norman K (2020) Age-related fatigue is associated with reduced mitochondrial function in peripheral blood mononuclear cells. Exp Gerontol 144:111177. | LEAK ROUTINE ET | ROX | Intact cells | Human | Blood cells |
Hedges 2020 Biosci Rep | 2020 | Hedges CP, Pham T, Shetty B, Masson SWC, Hickey AJR, Shepherd PR, Merry TL (2020) Prolonged treatment with a PI3K p110α inhibitor causes sex- and tissue-dependent changes in antioxidant content, but does not affect mitochondrial function. https://doi.org/10.1042/bsr20201128 | LEAK OXPHOS ET | N CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle Liver |
Padilla-Flores 2020 Biochem Biophys Res Commun | 2020 | Padilla-Flores T, Lopez-Gonzalez Z, Vaca L, Aparicio-Trejo OE, Briones-Herrera A, Riveros-Rosas H, Pedraza-Chaverri J, Leon-Aparicio D, Salvador C, Sampieri A, Escobar LI (2020) "Funny" channels in cardiac mitochondria modulate membrane potential and oxygen consumption. Biochem Biophys Res Commun 524:1030-36. | LEAK ROUTINE | ROX | Intact cells | Rat | Heart |
Rondot 2020 Thesis | 2020 | Rondot A (2020) Fuels for winter: the role of proline in overwintering bumblebee queens (Bombus impatiens). Master's Thesis 41. | LEAK OXPHOS | N S NS ROX | Permeabilized tissue | Hexapods | Skeletal muscle |
Assis-de-Lemos 2020 Curr Protoc Toxicol | 2020 | Assis-de-Lemos G, Ledur PF, Karmirian K, Rehen SK, Galina A (2020) A protocol to study mitochondrial function in human neural progenitors and iPSC-derived astrocytes. Curr Protoc Toxicol 85:e97. | LEAK ROUTINE ET | ROX | Intact cells | Human | Nervous system |
Robledo-Cadena 2020 Pharmaceuticals (Basel) | 2020 | Robledo-Cadena DX, Gallardo-Pérez JC, Dávila-Borja V, Pacheco-Velázquez SC, Belmont-Díaz JA, Ralph SJ, Blanco-Carpintero BA, Moreno-Sánchez R, Rodríguez-Enríquez S (2020) Non-steroidal anti-inflammatory drugs increase cisplatin, paclitaxel, and doxorubicin efficacy against human cervix cancer cells. Pharmaceuticals (Basel) 13:463. | LEAK | Intact cells | Human | Endothelial;epithelial;mesothelial cell HeLa Fibroblast | |
Wang 2020 J Mol Med (Berl) | 2020 | Wang SY, Zhu Siyu, Wu Jian, Zhang Maomao, Xu Yousheng, Xu Wei, Cui Jinjin, Yu Bo, Cao Wei, Liu Jingjin (2020) Exercise enhances cardiac function by improving mitochondrial dysfunction and maintaining energy homoeostasis in the development of diabetic cardiomyopathy. J Mol Med (Berl) 98:245-61. | LEAK OXPHOS | N ROX | Isolated mitochondria | Mouse | Heart |
Matsuo 2020 Am J Physiol Endocrinol Metab | 2020 | Matsuo FS, Araújo PHC, Mota RF, Carvalho AJR, Queiroz MS, Almeida BB, Ferreira KCOS, Metzner RJM, Ferrari GD, Alberici LC, Osako MK (2020) RANKL induces beige adipocyte differentiation in preadipocytes. Am J Physiol Endocrinol Metab 318:E866-77. | LEAK OXPHOS | N | Permeabilized cells | Mouse | Fat |
Dawid 2020 Biochim Biophys Acta Bioenerg | 2020 | Dawid C, Weber D, Musiol E, Janas V, Baur S, Lang R, Fromme T (2020) Comparative assessment of purified saponins as permeabilization agents during respirometry. Biochim Biophys Acta Bioenerg 1861:148251. | LEAK ROUTINE OXPHOS ET | N S Gp NS ROX | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse | Nervous system HEK |