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From Bioblast
Year | Reference | Coupling | Pathway | Preparation | Organism | Tissue;cell | |
---|---|---|---|---|---|---|---|
Reutzel 2018 Oxid Med Cell Longev | 2018 | Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Mouse | Nervous system |
Pape 2018 Nutrients | 2018 | Pape JA, Newey CR, Burrell HR, Workman A, Perry K, Bikman BT, Bridgewater LC, Grose JH (2018) Per-Arnt-Sim kinase (PASK) deficiency increases cellular respiration on a standard diet and decreases liver triglyceride accumulation on a western high-fat high-sugar diet. Nutrients 10:1990. | OXPHOS LEAK | NS | Permeabilized tissue | Mouse | Skeletal muscle Liver |
Kauppila 2018 Thesis | 2018 | Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart Liver |
Cardinale 2018 Thesis | 2018 | Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99. | LEAK OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Human | Skeletal muscle |
Dechandt 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Dechandt CR, Vicentini TM, Lanfredi GP, da Silva RMP Jr, Espreafico EM, de Oliveira JAC, Faça VM, Garcia-Cairasco N, Alberici LC (2018) The highly efficient power house in the Wistar Audiogenic Rat (WAR), an epileptic rat strain. Am J Physiol Regul Integr Comp Physiol 316:R243-R254. | LEAK OXPHOS ET | N ROX | Permeabilized tissue Isolated mitochondria | Rat | Heart Skeletal muscle Liver |
Siira 2018 EMBO Rep | 2018 | Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198. | LEAK OXPHOS ET | N S | Isolated mitochondria | Mouse | Heart |
Cecatto 2018 FEBS J | 2018 | Cecatto C, Amaral AU, da Silva JC, Wajner A, Schimit MOV, da Silva LHR, Wajner SM, Zanatta A, Castilho RF, Wajner M (2018) Metabolite accumulation in VLCAD deficiency markedly disrupts mitochondrial bioenergetics and Ca2+ homeostasis in the heart. FEBS J 285:1437-55. | LEAK OXPHOS ET | N S | Permeabilized cells Permeabilized tissue Isolated mitochondria | Rat | Heart Other cell lines |
Stepanova 2018 J Neurochem | 2018 | Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45. | LEAK OXPHOS | N S Gp NS ROX | Isolated mitochondria | Mouse | Nervous system |
Rekuviene 2018 Thesis | 2018 | Rekuvienė E (2018) Effect of respiratory complex I inhibitors on mitochondrial permeability transition and cell viability during brain ischemia. Doctoral Dissertation 138. | LEAK OXPHOS | N S | Isolated mitochondria | Rat | Nervous system |
Burstein 2018 Hum Mol Genet | 2018 | Burstein SR, Valsecchi F, Kawamata H, Bourens M, Zeng R, Zuberi A, Milner TA, Cloonan SM, Lutz C, Barrientos A, Manfredi G (2018) In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions. Hum Mol Genet 27:160-77. | LEAK OXPHOS ET | N CIV | Isolated mitochondria Intact cells | Human Mouse | Heart Skeletal muscle Nervous system HEK |
Manoharan 2018 Thesis | 2018 | Manoharan N (2018) Characterization of mitochondrial respiration in atlantic salmon (Salmo salar) fed with glutamate and succinate enhanced diet. Master's Thesis 52. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Fishes | Heart Liver |
Santos Bertolini 2018 Thesis | 2018 | Santos Bertolini M (2018) Functional study of MICU1 and MICU2 proteins in calcium signaling of Trypanosoma cruzi. Master's Thesis 108. | LEAK OXPHOS ET | S | Permeabilized cells | Protists | |
Astrakhanova 2018 Sovrem Tekhnologii Med | 2018 | Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94. | OXPHOS LEAK | N S | Isolated mitochondria | Mouse | Nervous system |
Krug 2018 Thesis | 2018 | Krug KP (2018) Adaptation of metabolism and respiratory chain functions in pulmonary arterial vascular muscle cells under chronic hypoxia: especially considering the cytochrome c oxidase subunit 4 isoform 2. Doctoral Dissertation 136. | LEAK ROUTINE OXPHOS ET | N S CIV ROX | Intact cells Permeabilized cells | Rat | Other cell lines |
Razak 2018 RUMeS | 2018 | Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Nervous system |
Fink 2018 J Biol Chem | 2018 | Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41. https://doi.org/10.1074/jbc.RA118.005144 | OXPHOS | N S NS | Isolated mitochondria | Mouse | Skeletal muscle |
Manakov 2018 J Physiol Biochem | 2018 | Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Rat | Heart |
Belosludtsev 2018 Biochim Biophys Acta | 2018 | Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97. | OXPHOS | N S NS | Isolated mitochondria | Rat | Liver |
Uribe-Alvarez 2018 Microbiologyopen | 2018 | Uribe-Alvarez C, Chiquete-Félix N, Morales-García L, Bohórquez-Hernández A, Delgado-Buenrostro NL, Vaca L, Peña A, Uribe-Carvajal S (2018) Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism. Microbiologyopen 8:e00675. | OXPHOS ET | CIV ROX N NS | Isolated mitochondria | Saccharomyces cerevisiae | |
Davila 2018 Elife | 2018 | Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:e33246. | LEAK OXPHOS ET | N | Isolated mitochondria | Mouse | Skeletal muscle Liver |
Britto 2018 BMC Biol | 2018 | Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65. https://doi.org/10.1186/s12915-018-0525-4 | LEAK OXPHOS | F N NS Other combinations | Permeabilized cells Isolated mitochondria | Mouse | Skeletal muscle |
Efimova 2018 Thesis | 2018 | Efimova I (2018) Structural composition and functional properties of mitochondrial FoF1 ATP synthase on models of specific subunits deficiencies. PhD Thesis 94. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | HEK |
Hollis 2018 Neuropharmacology | 2018 | Hollis F, Mitchell ES, Canto C, Wang D, Sandi C (2018) Medium chain triglyceride diet reduces anxiety-like behaviors and enhances social competitiveness in rats. Neuropharmacology 138:245-56. | OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Mahapatra 2018 Clin Sci (Lond) | 2018 | Mahapatra G, Smith SC, Hughes TM, Wagner B, Maldjian JA, Freedman BI, Molina AJA (2018) Blood-based bioenergetic profiling is related to differences in brain morphology in African Americans with Type 2 diabetes. Clin Sci (Lond) 132:2509-18. https://doi.org/10.1042/CS20180690 | LEAK OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells | Human | Nervous system Blood cells |
Dejmek 2018 Physiol Res | 2018 | Dejmek J, Kohoutová M, Kripnerová M, Čedíková M, Tůma Z, Babuška V, Bolek L, Kuncová J (2018) Repeated exposure to hyperbaric hyperoxia affects mitochondrial functions of the lung fibroblasts. Physiol Res 67(Suppl 4):S633-S643. | LEAK ROUTINE OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Intact cells | Human | Lung;gill Fibroblast |
Giordano 2018 Am J Respir Cell Mol Biol | 2018 | Giordano L, Farnham A, Dhandapani PK, Salminen L, Bhaskaran J, Voswinckel R, Rauschkolb P, Scheibe S, Sommer N, Beisswenger C, Weissmann N, Braun T, Jacobs HT, Bals R, Herr C, Szibor M (2018) Alternative oxidase attenuates cigarette smoke-induced lung dysfunction and tissue damage. Am J Respir Cell Mol Biol 60:515-22. | OXPHOS | N S CIV ROX | Permeabilized cells | Mouse | Fibroblast |
Lai 2018 Acta Physiol (Oxf) | 2018 | Lai N, M Kummitha C, Rosca MG, Fujioka H, Tandler B, Hoppel CL (2018) Isolation of mitochondrial subpopulations from skeletal muscle: optimizing recovery and preserving integrity. Acta Physiol (Oxf) e13182. doi: 10.1111/apha.13182. | LEAK OXPHOS ET | N | Isolated mitochondria | Rat | Skeletal muscle |
Christen 2018 Free Radic Biol Med | 2018 | Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Fishes | Heart |
Zhang 2018 Cardiovasc Diabetol | 2018 | Zhang X, Zhang Z, Yang Y, Suo Y, Liu R, Qiu J, Zhao Y, Jiang N, Liu C, Tse G, Li G, Liu T (2018) Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits. Cardiovasc Diabetol 17:160. | OXPHOS LEAK | N | Isolated mitochondria | Rabbit | Heart |
Gratl 2018 Thesis | 2018 | Gratl A (2018) High-resolution respirometry for measurement of mitochondrial function in PAD patients before and after revascularisation. PhD Thesis 69. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Van der Kooij 2018 Mol Psychiatry | 2018 | van der Kooij MA, Hollis F, Lozano L, Zalachoras I, Abad S, Zanoletti O, Grosse J, Guillot de Suduiraut I, Canto C, Sandi C (2018) Diazepam actions in the VTA enhance social dominance and mitochondrial function in the nucleus accumbens by activation of dopamine D1 receptors. Mol Psychiatry 23:569-78. | OXPHOS ET | N S NS ROX | Homogenate | Rat | Nervous system |
Apostolopoulou 2018 Thesis | 2018 | Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77. | OXPHOS ET | F N NS | Homogenate Isolated mitochondria | Human | Liver |
Reguis Yadao 2018 Thesis | 2018 | Reguis Yadao DR (2018) Smooth muscle cell mitochondrial respiration – effects of aerobic training and type I diabetes. Master's Thesis 71. | LEAK OXPHOS | N NS ROX | Permeabilized tissue | Mouse | Other cell lines |
Hayward 2018 Thesis | 2018 | Hayward L (2018) The effect of anoxia on mitochondrial function in a hibernator (Ictidomys tridecemlineatus). Master's Thesis 57. | OXPHOS LEAK | N NS | Isolated mitochondria | Other mammals | Liver |
Fox 2018 Thesis | 2018 | Fox JC (2018) FROST450, a novel microtubule targeting agent: resistance and cross-resistance in an ovarian cancer cell line. Bachelor's Thesis 27. | LEAK OXPHOS ET | N NS ROX | Intact cells | Human | Genital |
Papadimitriou 2018 Thesis | 2018 | Papadimitriou ID (2018) The influence of ACTN3 R577X genotype on performance and muscle adaptations to a single bout of exercise . PhD Thesis 125. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Simard 2018 J Vis Exp | 2018 | Simard CJ, Pelletier G, Boudreau LH, Hebert-Chatelain E, Pichaud N (2018) Measurement of mitochondrial oxygen consumption in permeabilized fibers of Drosophila using minimal amounts of tissue. J Vis Exp 134. | LEAK OXPHOS | N Gp CIV NS ROX | Permeabilized tissue | Drosophila | |
Urazov 2018 Sovrem Tekhnologii Med | 2018 | Urazov MD, Astrakhanova TA, Usenko AV, Mishchenko TA, Schelchkova NA, Kravchenko GA, Vedunova MV, Mitroshina EV (2018) New aspects of central nervous system adaptation to prenatal hypoxia. Sovrem Tekhnologii Med 10:60-68. | OXPHOS LEAK | N S NS | Isolated mitochondria | Mouse | Nervous system |
D'Souza 2018 J Lipid Res | 2018 | D'Souza K, Nzirorera C, Cowie AM, Varghese GP, Trivedi P, Eichmann TO, Biswas D, Touaibia M, Morris AJ, Aidinis V, Kane DA, Pulinilkunnil T, Kienesberger PC (2018) Autotaxin-LPA signaling contributes to obesity-induced insulin resistance in muscle and impairs mitochondrial metabolism. J Lipid Res 59:1805-17. | LEAK OXPHOS | F N S ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Zdralevic 2018 J Biol Chem | 2018 | Ždralević M, Brand A, Di Ianni L, Dettmer K, Reinders J, Singer K, Peter K, Schnell A, Bruss C, Decking SM, Koehl G, Felipe-Abrio B, Durivault J, Bayer P, Evangelista M, O'Brien T, Oefner PJ, Renner K, Pouysségur J, Kreutz M (2018) Double genetic disruption of lactate dehydrogenase A and B is required to ablate the 'Warburg effect' restricting tumor growth to oxidative metabolism. J Biol Chem 293:15947-61. | LEAK OXPHOS ET | N NS ROX | Permeabilized cells Intact cells | Human | Endothelial;epithelial;mesothelial cell |
Aparicio-Trejo 2018 Free Radic Biol Med | 2018 | Aparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96. | LEAK OXPHOS | N S NS ROX | Intact cells Isolated mitochondria | Rat | Kidney |
Fisher-Wellman 2018 Cell Rep | 2018 | Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606. | LEAK OXPHOS | F N S | Isolated mitochondria | Mouse | Heart Skeletal muscle |
Tripodi 2018 Biochim Biophys Acta Mol Cell Res | 2018 | Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13. | OXPHOS LEAK | N S | Isolated mitochondria | Saccharomyces cerevisiae | |
Holland 2018 Cell Death Dis | 2018 | Holland OJ, Cuffe JSM, Dekker Nitert M, Callaway L, Kwan Cheung KA, Radenkovic F, Perkins AV (2018) Placental mitochondrial adaptations in preeclampsia associated with progression to term delivery. Cell Death Dis 9:1150. | LEAK OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Human | Genital |
Zhang 2018 Aging Dis | 2018 | Zhang L, Hao J, Zheng Y, Su R, Liao Y, Gong X, Liu L, Wang X (2018) Fucoidan protects dopaminergic neurons by enhancing the mitochondrial function in a rotenone-induced rat model of Parkinson’s disease. Aging Dis 9:590-604. | LEAK OXPHOS ET | N S ROX | Permeabilized tissue Homogenate | Rat | Nervous system |
Kjeld 2018 PLoS One | 2018 | Kjeld T, Stride N, Gudiksen A, Hansen EG, Arendrup HC, Horstmann PF, Zerahn B, Jensen LT, Nordsborg N, Bejder J, Halling JF (2018) Oxygen conserving mitochondrial adaptations in the skeletal muscles of breath hold divers. PLoS One 13:e0201401. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Monzio Compagnoni 2018 Biochim Biophys Acta Mol Basis Dis | 2018 | Monzio Compagnoni G, Kleiner G, Bordoni A, Fortunato F, Ronchi D, Salani S, Guida M, Corti C, Pichler I, Bergamini C, Fato R, Pellecchia MT, Vallelunga A, Del Sorbo F, Elia A, Reale C, Garavaglia B, Mora G, Albanese A, Cogiamanian F, Ardolino G, Bresolin N, Corti S, Comi GP, Quinzii CM, Di Fonzo A (2018) Mitochondrial dysfunction in fibroblasts of multiple system atrophy. Biochim Biophys Acta Mol Basis Dis 1864:3588-97. | OXPHOS ET ROUTINE | N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Budai 2018 Br J Surg | 2018 | Budai A, Horváth G, Tretter L, Radák Z, Koltai E, Bori Z, Torma F, Lukáts Á, Röhlich P, Szijártó A, Fülöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31. | OXPHOS | N S | Isolated mitochondria | Rat | Liver |
McWilliams 2018 Open Biol | 2018 | McWilliams TG, Barini E, Pohjolan-Pirhonen R, Brooks SP, Singh F, Burel S, Balk K, Kumar A, Montava-Garriga L, Prescott AR, Hassoun SM, Mouton-Liger F, Ball G, Hills R, Knebel A, Ulusoy A, Di Monte DA, Tamjar J, Antico O, Fears K, Smith L, Brambilla R, Palin E, Valori M, Eerola-Rautio J, Tienari P, Corti O, Dunnett SB, Ganley IG, Suomalainen A, Muqit MMK (2018) Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. Open Biol 8:180108. | LEAK OXPHOS ET | N | Homogenate | Mouse | Nervous system |
Maurya 2018 Cell Rep | 2018 | Maurya SK, Herrera JL, Sahoo SK, Reis FCG, Vega RB, Kelly DP, Periasamy M (2018) Sarcolipin signaling promotes mitochondrial biogenesis and oxidative metabolism in skeletal muscle. Cell Rep 24:2919-31. | OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Lander 2018 J Biol Chem | 2018 | Lander N, Chiurillo MA, Bertolini MS, Storey M, Vercesi AE, Docampo R (2018) Calcium-sensitive pyruvate dehydrogenase phosphatase is required for energy metabolism, growth, differentiation, and infectivity of Trypanosoma cruzi. J Biol Chem 293:17402-17. | LEAK OXPHOS ET | N S | Permeabilized cells | Protists | |
Sims 2018 JCI Insight | 2018 | Sims CA, Guan Y, Mukherjee S, Singh K, Botolin P, Davila A Jr, Baur JA (2018) Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI Insight 3:120182. | OXPHOS | N S CIV ROX | Permeabilized cells Isolated mitochondria | Rat | Liver Kidney |
Dandanell 2018 Scand J Med Sci Sports | 2018 | Dandanell S, Meinild-Lundby AK, Andersen AB, Lang PF, Oberholzer L, Keiser S, Robach P, Larsen S, Rønnestad BR, Lundby C (2018) Determinants of maximal whole-body fat oxidation in elite cross-country skiers: role of skeletal muscle mitochondria. Scand J Med Sci Sports 28:2494-504. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Nelson 2018 Amino Acids | 2018 | Nelson MM, Builta ZJ, Monroe TB, Doorn JA, Anderson EJ (2018) Biochemical characterization of the catecholaldehyde reactivity of L-carnosine and its therapeutic potential in human myocardium. Amino Acids 51:97-102. | OXPHOS | Permeabilized tissue | Human | Heart | |
Cardinale 2018 Front Physiol | 2018 | Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133. | OXPHOS | F N NS | Isolated mitochondria | Human | Skeletal muscle |
Stepanova 2018 J Cereb Blood Flow Metab | 2018 | Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab 39:1790-802. | OXPHOS ET LEAK | N S ROX | Isolated mitochondria | Rat | Nervous system |
Kahl 2018 Stroke | 2018 | Kahl A, Stepanova A, Konrad C, Anderson C, Manfredi G, Zhou P, Iadecola C, Galkin A (2018) Critical role of flavin and glutathione in complex I-mediated bioenergetic failure in brain ischemia/reperfusion injury. Stroke 49:1223-31. | LEAK OXPHOS | CIV | Homogenate | Mouse | Nervous system |
Cronin 2018 Nature | 2018 | Cronin SJF, Seehus C, Weidinger A, Talbot S, Reissig S, Seifert M, Pierson Y, McNeill E, Longhi MS, Turnes BL, Kreslavsky T, Kogler M, Hoffmann D, Ticevic M, da Luz Scheffer D, Tortola L, Cikes D, Jais A, Rangachari M, Rao S, Paolino M, Novatchkova M, Aichinger M, Barrett L, Latremoliere A, Wirnsberger G, Lametschwandtner G, Busslinger M, Zicha S, Latini A, Robson SC, Waisman A, Andrews N, Costigan M, Channon KM, Weiss G, Kozlov AV, Tebbe M, Johnsson K, Woolf CJ, Penninger JM (2018) The metabolite BH4 controls T cell proliferation in autoimmunity and cancer. Nature 563:564-68. | ROUTINE OXPHOS ET LEAK | N S | Permeabilized cells Intact cells | Mouse | Lymphocyte |
Puurand 2018 Int J Mol Sci | 2018 | Puurand M, Tepp K, Klepinin A, Klepinina L, Shevchuk I, Kaambre T (2018) Intracellular energy-transfer networks and high-resolution respirometry: a convenient approach for studying their function. Int J Mol Sci 19:e2933. | OXPHOS | N | Permeabilized cells | ||
Pardo 2018 FASEB J | 2018 | Pardo R, Vilà M, Cervela L, de Marco M, Gama-Pérez P, González-Franquesa A, Statuto L, Vilallonga R, Simó R, Garcia-Roves PM, Villena JA (2018) Calorie restriction prevents diet-induced insulin resistance independently of PGC-1-driven mitochondrial biogenesis in white adipose tissue. FASEB J 33:2343-58. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Fat |
Jelenik 2018 Diabetes | 2018 | Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702. | LEAK OXPHOS | F N NS ROX | Permeabilized tissue Isolated mitochondria | Human Mouse | Heart |
Keller 2018 Oxid Med Cell Longev | 2018 | Keller AC, Knaub LA, Scalzo RL, Hull SE, Johnston AE, Walker LA, Reusch JEB (2018) Sepiapterin improves vascular reactivity and insulin-stimulated glucose in wistar rats. Oxid Med Cell Longev 2018:7363485. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Rat | Endothelial;epithelial;mesothelial cell |
Ko 2018 Pflugers Arch | 2018 | Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75. | LEAK OXPHOS | N ROX | Isolated mitochondria | Rat | Heart |
Angebault 2018 Sci Signal | 2018 | Angebault C, Fauconnier J, Patergnani S, Rieusset J, Danese A, Affortit CA, Jagodzinska J, Mégy C, Quiles M, Cazevieille C, Korchagina J, Bonnet-Wersinger D, Milea D, Hamel C, Pinton P, Thiry M, Lacampagne A, Delprat B, Delettre C (2018) ER-mitochondria cross-talk is regulated by the Ca2+ sensor NCS1 and is impaired in Wolfram syndrome. Sci Signal 11:eaaq1380. | LEAK OXPHOS | N S NS | Permeabilized cells | Human | Fibroblast |
Rocha 2018 J Physiol Biochem | 2018 | Rocha C, Koury OH, Scheede-Bergdahl C, Bergdahl A (2018) Cardiac mitochondrial respiration following a low-carbohydrate, high-fat diet in apolipoprotein E-deficient mice. J Physiol Biochem 75:65-72. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Mouse | Heart |
Arnoux 2018 Elife | 2018 | Arnoux I, Willam M, Griesche N, Krummeich J, Watari H, Offermann N, Weber S, Narayan Dey P, Chen C, Monteiro O, Buettner S, Meyer K, Bano D, Radyushkin K, Langston R, Lambert JJ, Wanker E, Methner A, Krauss S, Schweiger S, Stroh A (2018) Metformin reverses early cortical network dysfunction and behavior changes in Huntington's disease. Elife 7:e38744. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Dohlmann 2018 Physiol Rep | 2018 | Dohlmann TL, Hindsø M, Dela F, Helge JW, Larsen S (2018) High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle. Physiol Rep 6:e13857. | OXPHOS ET | N NS | Permeabilized tissue | Human | Skeletal muscle Fat |
De Moura Alvorcem 2018 Mitochondrion | 2018 | De Moura Alvorcem L, Britto R, Parmeggiani B, Glanzel NM, Da Rosa-Junior NT, Cecatto C, Bobermin LD, Amaral AU, Wajner M, Leipnitz G (2018) Evidence that thiol group modification and reactive oxygen species are involved in hydrogen sulfide-induced mitochondrial permeability transition pore opening in rat cerebellum. Mitochondrion 47:141-50. | LEAK OXPHOS ET | N S NS | Isolated mitochondria Intact cells | Rat | Nervous system |
Sprenger 2018 EMBO Mol Med | 2018 | Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2018) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11:e9288. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Mouse | Nervous system |
Laouafa 2018 Adv Exp Med Biol | 2018 | Laouafa S, Roussel D, Marcouiller F, Soliz J, Bairam A, Joseph V (2018) Role of estradiol receptor beta (ERβ) on arterial pressure, respiratory chemoreflex and mitochondrial function in young and aged female mice. Adv Exp Med Biol 1071:115-27. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Mouse | Nervous system |
Fischer 2018 BMC Musculoskelet Disord | 2018 | Fischer MJ, Horvath G, Krismer M, Gnaiger E, Goebel G, Pesta DH (2018) Evaluation of mitochondrial function in chronic myofascial trigger points - a prospective cohort pilot study using high-resolution respirometry. BMC Musculoskelet Disord 19:388. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Tosi 2018 J Bioenerg Biomembr | 2018 | Tosi I, Art T, Cassart D, Farnir F, Ceusters J, Serteyn D, Lemieux H, Votion DM (2018) Altered mitochondrial oxidative phosphorylation capacity in horses suffering from polysaccharide storage myopathy. J Bioenerg Biomembr 50:379-90. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Horse | Skeletal muscle |
Kim 2018 Pflugers Arch | 2018 | Kim Y, Triolo M, Erlich AT, Hood DA (2018) Regulation of autophagic and mitophagic flux during chronic contractile activity-induced muscle adaptations. Pflugers Arch 471:431-40. | OXPHOS | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Takahashi 2018 Sci Rep | 2018 | Takahashi K, Miura Y, Ohsawa I, Shirasawa T, Takahashi M (2018) In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep 8:15585. | OXPHOS | N | Isolated mitochondria | Mouse | Nervous system |
Ryan 2018 JCI Insight | 2018 | Ryan TE, Yamaguchi DJ, Schmidt CA, Zeczycki TN, Shaikh SR, Brophy P, Green TD, Tarpey MD, Karnekar R, Goldberg EJ, Sparagna GC, Torres MJ, Annex BH, Neufer PD, Spangenburg EE, McClung JM (2018) Extensive skeletal muscle cell mitochondriopathy distinguishes critical limb ischemia patients from claudicants. JCI Insight 3:123235. | OXPHOS LEAK | N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Falcao-Tebas 2018 J Physiol | 2018 | Falcão-Tebas F, Kuang J, Arceri C, Kerris JP, Andrikopoulos S, Marin EC, McConell GK (2018) Four weeks of exercise early in life reprograms adult skeletal muscle insulin resistance caused by paternal high fat diet. J Physiol 597:121-36. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Rossignoli 2018 J Nutr Biochem | 2018 | Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23. | LEAK ET OXPHOS | N S | Permeabilized cells Isolated mitochondria | Mouse | Skeletal muscle Nervous system Liver Fat |
Johnson 2018 J Mol Cell Cardiol | 2018 | Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K (2018) Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. J Mol Cell Cardiol 121:94-102. | OXPHOS ET | F N S NS | Isolated mitochondria | Mouse | Heart Skeletal muscle |
Burney 2018 Thesis | 2018 | Burney E (2018) Characterization of mitochondrial metabolism in L6 rat myoblasts. Bachelor's Thesis p50. | LEAK ROUTINE OXPHOS ET | F N S Gp NS Other combinations ROX | Permeabilized cells Intact cells | Rat | Other cell lines |
Musi 2018 Aging Cell | 2018 | Musi N, Valentine JM, Sickora KR, Baeuerle E, Thompson CS, Shen Q, Orr ME (2018) Tau protein aggregation is associated with cellular senescence in the brain. Aging Cell 17:e12840. | LEAK OXPHOS ET | F N S NS | Homogenate | Mouse | Nervous system |
Trumbeckaite 2018 J Bioenerg Biomembr | 2018 | Trumbeckaite S, Cesna V, Jasukaitiene A, Baniene R, Gulbinas A (2018) Different mitochondrial response to cisplatin and hyperthermia treatment in human AGS, Caco-2 and T3M4 cancer cell lines. J Bioenerg Biomembr 50:329-38. | OXPHOS | N S | Permeabilized cells | Human | Other cell lines |
Ramil 2018 Thesis | 2018 | Ramil LR, Gulbinas A, Cesna V (2018) “HIPEC” hyperthermic intraperitoneal chemotherapy. Evaluation of intraperitoneal free cancer cells. Master's Thesis. | OXPHOS LEAK | N S | Isolated mitochondria | Human | Endothelial;epithelial;mesothelial cell |
Karlsson 2018 J Neurotrauma | 2018 | Karlsson M, Pukenas B, Chawla S, Ehinger JK, Plyler R, Stolow M, Gabello M, Hugerth M, Elmér E, Hansson MJ, Margulies S, Kilbaugh T (2018) Neuroprotective effects of cyclosporine in a porcine pre-clinical trial of focal traumatic brain injury. J Neurotrauma 36:14-24. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Okerblom 2018 Proc Biol Sci | 2018 | Okerblom J, Fletes W, Patel HH, Schenk S, Varki A, Breen EC (2018) Human-like Cmah inactivation in mice increases running endurance and decreases muscle fatigability: implications for human evolution. Proc Biol Sci 285:20181656. | OXPHOS LEAK | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Audia 2018 Basic Res Cardiol | 2018 | Audia JP, Yang XM, Crockett ES, Housley N, Haq EU, O'Donnell K, Cohen MV, Downey JM, Alvarez DF (2018) Caspase‑1 inhibition by VX‑765 administered at reperfusion in P2Y12 receptor antagonist‑treated rats provides long‑term reduction in myocardial infarct size and preservation of ventricular function. Basic Res Cardiol 113:32. | OXPHOS ET | N S CIV NS ROX | Permeabilized tissue | Rat | Heart |
Champigny 2018 Mar Drugs | 2018 | Champigny CM, Cormier RPJ, Simard CJ, St-Coeur PD, Fortin S, Pichaud N (2018) Omega-3 monoacylglyceride effects on longevity, mitochondrial metabolism and oxidative stress: insights from Drosophila melanogaster. Mar Drugs 16:E453. | LEAK OXPHOS ET | N S NS ROX Gp | Permeabilized tissue | Drosophila | |
Lobo-Jarne 2018 Cell Rep | 2018 | Lobo-Jarne T, Nývltová E, Pérez-Pérez R, Timón-Gómez A, Molinié T, Choi A, Mourier A, Fontanesi F, Ugalde C, Barrientos A (2018) Human COX7A2L regulates complex III biogenesis and promotes supercomplex organization remodeling without affecting mitochondrial bioenergetics. Cell Rep 25:1786-99. | LEAK OXPHOS ET | N S NS ROX Gp | Permeabilized cells | Human | HEK Other cell lines |
Kleszczynski 2018 Int J Mol Sci | 2018 | Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786. | LEAK OXPHOS | N NS | Isolated mitochondria | Mouse | Liver |
Schiffer 2018 PLoS One | 2018 | Schiffer TA, Christensen M, Gustafsson H, Palm F (2018) The effect of inactin on kidney mitochondrial function and production of reactive oxygen species. PLoS One 13:e0207728. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Kidney |
Wilmanns 2018 Mol Metab | 2018 | Wilmanns JC, Pandey R, Hon O, Chandran A, Schilling JM, Forte E, Wu Q, Cagnone G, Bais P, Philip V, Coleman D, Kocalis H, Archer SK, Pearson JT, Ramialison M, Heineke J, Patel HH, Rosenthal NA, Furtado MB, Costa MW (2018) Metformin intervention prevents cardiac dysfunction in a murine model of adult congenital heart disease. Mol Metab 20:102-14. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Mouse | Heart |
Friederich 2018 Nat Commun | 2018 | Friederich MW, Timal S, Powell CA, Dallabona C, Kurolap A, Palacios-Zambrano S, Bratkovic D, Derks TGJ, Bick D, Bouman K, Chatfield KC, Damouny-Naoum N, Dishop MK, Falik-Zaccai TC, Fares F, Fedida A, Ferrero I, Gallagher RC, Garesse R, Gilberti M, González C, Gowan K, Habib C, Halligan RK, Kalfon L, Knight K, Lefeber D, Mamblona L, Mandel H, Mory A, Ottoson J, Paperna T, Pruijn GJM, Rebelo-Guiomar PF, Saada A, Sainz B Jr, Salvemini H, Schoots MH, Smeitink JA, Szukszto MJ, Ter Horst HJ, van den Brandt F, van Spronsen FJ, Veltman JA, Wartchow E, Wintjes LT, Zohar Y, Fernández-Moreno MA, Baris HN, Donnini C, Minczuk M, Rodenburg RJ, Van Hove JLK (2018) Pathogenic variants in glutamyl-tRNAGln amidotransferase subunits cause a lethal mitochondrial cardiomyopathy disorder. Nat Commun 9:4065. | ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human Fungi | Fibroblast |
Harmuth 2018 Front Mol Neurosci | 2018 | Harmuth T, Prell-Schicker C, Weber JJ, Gellerich F, Funke C, Drießen S, Magg JCD, Krebiehl G, Wolburg H, Hayer SN, Hauser S, Krüger R, Schöls L, Riess O, Hübener-Schmid J (2018) Mitochondrial morphology, function and homeostasis are impaired by expression of an N-terminal calpain cleavage fragment of Ataxin-3. Front Mol Neurosci 11:368. | LEAK ET ROUTINE OXPHOS | N S | Homogenate Intact cells | Mouse | Fibroblast |
Treberg 2018 Redox Biol | 2018 | Treberg JR, Braun K, Selseleh P (2018) Mitochondria can act as energy-sensing regulators of hydrogen peroxide availability. Redox Biol 20:483-88. | LEAK OXPHOS ET | S | Isolated mitochondria | Rat | Skeletal muscle |
Dogan 2018 Cell Metab | 2018 | Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77. | LEAK OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Skeletal muscle |
Larsen 2018 Physiol Rep | 2018 | Larsen S, Lundby AM, Dandanell S, Oberholzer L, Keiser S, Andersen AB, Haider T, Lundby C (2018) Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males. Physiol Rep 6:e13793. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Briones-Herrera 2018 Food Chem Toxicol | 2018 | Briones-Herrera A, Avila-Rojas SH, Aparicio-Trejo OE, Cristóbal M, León-Contreras JC, Hernández-Pando R, Pinzón E, Pedraza-Chaverri J, Sánchez-Lozada LG, Tapia E (2018) Sulforaphane prevents maleic acid-induced nephropathy by modulating renal hemodynamics, mitochondrial bioenergetics and oxidative stress. Food Chem Toxicol 115:185-97. | LEAK OXPHOS | N NS S | Isolated mitochondria | Rat | Kidney |
Mayer 2018 Endocrinology | 2018 | Mayer AL, Zhang Y, Feng EH, Higgins CB, Adenekan O, Pietka TA, Beatty WL, DeBosch BJ (2018) Enhanced hepatic PPARα activity links GLUT8 deficiency to augmented peripheral fasting responses in male mice. Endocrinology 159:2110-26. | OXPHOS ET | N S NS ROX | Permeabilized tissue Homogenate | Mouse | Skeletal muscle Liver |
Rajasekaran 2018 FASEB J | 2018 | Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61. | LEAK OXPHOS ET | N S CIV ROX | Isolated mitochondria | Mouse | Liver |
Brouwers 2018 Front Physiol | 2018 | Brouwers B, Stephens NA, Costford SR, Hopf ME, Ayala JE, Yi F, Xie H, Li JL, Gardell SJ, Sparks LM, Smith SR (2018) Elevated nicotinamide phosphoribosyl transferase in skeletal muscle augments exercise performance and mitochondrial respiratory capacity following exercise training. Front Physiol 9:704. | OXPHOS ET | F N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Schiffer 2018 Am J Physiol Renal Physiol | 2018 | Schiffer TA, Gustafsson H, Palm F (2018) Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment. Am J Physiol Renal Physiol 315:F677-F681. | LEAK OXPHOS | N NS | Isolated mitochondria | Rat | Kidney |
Carter 2018 J Appl Physiol (1985) | 2018 | Carter HN, Pauly M, Tryon LD, Hood DA (2018) Effect of contractile activity on PGC-1α transcription in young and aged skeletal muscle. J Appl Physiol (1985) 124:1605-15. | OXPHOS | N | Intact cells | Rat | Skeletal muscle |
Monaco 2018 Am J Physiol Regul Integr Comp Physiol | 2018 | Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204. | LEAK OXPHOS | N NS | Permeabilized tissue Isolated mitochondria | Rat | Heart |
Real-Hohn 2018 bioRxiv | 2018 | Real-Hohn A, Navegantes C, Ramos K, Ramos-Filho D, Cahuê F, Galina A, Salerno V (2018) Hexokinase: a central player in the synergism of high-intensity intermittent exercise and every-other-day intermittent fasting regimen on energy metabolism adaptations. bioRxiv doi: https://doi.org/10.1101/389668. | LEAK OXPHOS ET | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Barbeau 2018 Biochem J | 2018 | Barbeau PA, Miotto PM, Holloway GP (2018) Mitochondrial derived reactive oxygen species influence ADP sensitivity, but not CPT-I substrate sensitivity. Biochem J 475:2997-3008. | OXPHOS | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Kang 2018 Exp Mol Med | 2018 | Kang YC, Son M, Kang S, Im S, Piao Y, Lim KS, Song MY, Park KS, Kim YH, Pak YK (2018) Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson's disease models. Exp Mol Med 50:105. | OXPHOS | N | Isolated mitochondria | Human | Nervous system |
Kim 2018 Free Radic Biol Med | 2018 | Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124:517-24. | OXPHOS | N S | Isolated mitochondria | Mouse | Nervous system |
Burtscher 2018 Front Mol Neurosci | 2018 | Burtscher J, Bean C, Zangrandi L, Kmiec I, Agostinho A, Scorrano L, Gnaiger E, Schwarzer C (2018) Proenkephalin derived peptides are involved in the modulation of mitochondrial respiratory control during epileptogenesis. Front Mol Neurosci doi:10.3389/fnmol.2018.00351. | LEAK OXPHOS ET | N S NS ROX | Homogenate | Mouse | Nervous system |
Cooper 2018 Exp Physiol | 2018 | Cooper MA, McCoin C, Pei D, Thyfault JP, Koestler D, Wright DE (2018) Reduced mitochondrial reactive oxygen species production in peripheral nerves of mice fed a ketogenic diet. Exp Physiol 103:1206-12. | OXPHOS ET LEAK | F N NS | Permeabilized tissue | Mouse | Nervous system |
Miotto 2018 Thesis | 2018 | Miotto PM (2018) The influence of exercise and high fat feeding on the regulation of mitochondrial substrate sensitivity in skeletal muscle. PhD Thesis p185. | OXPHOS | F N NS | Permeabilized cells | Mouse | Skeletal muscle |
Von Schulze 2018 J Physiol | 2018 | Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α, and BNIP3 mediated mitophagy. J Physiol 596:6157-71. | OXPHOS ET | F N NS | Isolated mitochondria | Mouse | Liver |
Kovalcikova 2018 Thesis | 2018 | Kovalčíková J (2018) Functional characterisation of new components of mitochondrial proteome. PhD Thesis p104. | LEAK OXPHOS ET | N NS | Homogenate | Mouse Rat | Heart Liver |
Magnifico 2018 Oxid Med Cell Longev | 2018 | Magnifico MC, Xhani M, Popov M, Saso L, Sarti P, Arese M (2018) Nonylphenol and octylphenol differently affect cell redox balance by modulating the nitric oxide signaling. Oxid Med Cell Longev 2018:1684827. | ROUTINE OXPHOS | N S CIV ROX | Permeabilized cells Intact cells | Human | Liver Other cell lines |
Marie 2018 Cell Death Dis | 2018 | Marie M, Bigot K, Angebault C, Barrau C, Gondouin P, Pagan D, Fouquet S, Villette T, Sahel JA, Lenaers G, Picaud S (2018) Light action spectrum on oxidative stress and mitochondrial damage in A2E-loaded retinal pigment epithelium cells. Cell Death Dis 9:287. | LEAK OXPHOS ET | N S NS | Permeabilized cells | Endothelial;epithelial;mesothelial cell | |
Fuhrmann 2018 Cell Mol Life Sci | 2018 | Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67. | LEAK ROUTINE OXPHOS ET | N S ROX | Isolated mitochondria Intact cells | Human | |
Sokolov 2018 Mitochondrion | 2018 | Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37. | LEAK OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Molluscs | Lung;gill |
Bryant 2018 Thesis | 2018 | Bryant HJ (2018) The role of mitochondrial uncoupling in temperature responses in Atlantic killifish, Fundulus heteroclitus. Master's Thesis p126. | LEAK OXPHOS ET | F S | Isolated mitochondria | Fishes | Nervous system Liver Fat |
Arena 2018 Mol Cell | 2018 | Arena G, Cissé MY, Pyrdziak S, Chatre L, Riscal R, Fuentes M, Arnold JJ, Kastner M, Gayte L, Bertrand-Gaday C, Nay K, Angebault-Prouteau C, Murray K, Chabi B, Koechlin-Ramonatxo C, Orsetti B, Vincent C, Casas F, Marine JC, Etienne-Manneville S, Bernex F, Lombès A, Cameron CE, Dubouchaud H, Ricchetti M, Linares LK, Le Cam L (2018) Mitochondrial MDM2 regulates respiratory complex I activity independently of p53. Mol Cell 69:594-609. | OXPHOS | N S NS | Permeabilized cells | Human | Lung;gill Other cell lines |
Scaini 2018 Eur Neuropsychopharmacol | 2018 | Scaini G, Quevedo J, Velligan D, Roberts DL, Raventos H, Walss-Bass C (2018) Second generation antipsychotic-induced mitochondrial alterations: Implications for increased risk of metabolic syndrome in patients with schizophrenia. Eur Neuropsychopharmacol 28:369-80. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Human | Other cell lines Lymphocyte |
Warnsmann 2018 Mech Ageing Dev | 2018 | Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58. | LEAK OXPHOS ET | N | Isolated mitochondria | Fungi | |
Doerrier 2018 Methods Mol Biol | 2018 | Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70. https://doi.org/10.1007/978-1-4939-7831-1_3 | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS Other combinations ROX | Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells | Human Mouse Rat Saccharomyces cerevisiae | Heart Skeletal muscle Endothelial;epithelial;mesothelial cell Blood cells HEK Platelet |
Tetri 2018 Front Physiol | 2018 | Tetri LH, Diffee GM, Barton GP, Braun RK, Yoder HE, Haraldsdottir K, Eldridge MW, Goss KN (2018) Sex-specific skeletal muscle fatigability and decreased mitochondrial oxidative capacity in adult rats exposed to postnatal hyperoxia. Front Physiol 9:326. | LEAK OXPHOS ET | N S CIV ROX | Permeabilized tissue | Rat | Skeletal muscle |
Coleman 2018 Sci Rep | 2018 | Coleman V, Sa-Nguanmoo P, Koenig J, Schulz TJ, Grune T, Klaus S, Kipp AP, Ost M (2018) Partial involvement of Nrf2 in skeletal muscle mitohormesis as an adaptive response to mitochondrial uncoupling. Sci Rep 8:2446. | LEAK OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Chicco 2018 J Biol Chem | 2018 | Chicco AJ, Le CH, Gnaiger E, Dreyer HC, Muyskens JB, D'Alessandro A, Nemkov T, Hocker AD, Prenni JE, Wolfe LM, Sindt NM, Lovering AT, Subudhi AW, Roach RC (2018) Adaptive remodeling of skeletal muscle energy metabolism in high-altitude hypoxia: Lessons from AltitudeOmics. J Biol Chem 293:6659-71. | LEAK OXPHOS ET | F N S | Permeabilized tissue | Human | Skeletal muscle |
Bhaskaran 2018 EMBO Rep | 2018 | Bhaskaran S, Pharaoh G, Ranjit R, Murphy A, Matsuzaki S, Nair BC, Forbes B, Gispert S, Auburger G, Humphries KM, Kinter M, Griffin TM, Deepa SS (2018) Loss of mitochondrial protease ClpP protects mice from diet-induced obesity and insulin resistance. EMBO Rep 19. pii: e45009. | LEAK OXPHOS | N S NS | Mouse | Fat | |
Logan 2018 Mol Metab | 2018 | Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55. | LEAK OXPHOS | N S NS | Isolated mitochondria | Mouse | Nervous system |
Holloway 2018 Cell Rep | 2018 | Holloway GP, Holwerda AM, Miotto PM, Dirks ML, Verdijk LB, van Loon LJC (2018) Age-associated impairments in mitochondrial ADP sensitivity contribute to redox stress in senescent human skeletal muscle. Cell Rep 22:2837–48. | OXPHOS ET LEAK | N S NS | Permeabilized tissue | Human | Skeletal muscle |
Rampello 2018 Microb Cell | 2018 | Rampello NG, Stenger M, Westermann B, Osiewacz HD (2018) Impact of F1Fo-ATP-synthase dimer assembly factors on mitochondrial function and organismic aging. Microb Cell 5:198–207. | OXPHOS | N CIV | Isolated mitochondria | Fungi | |
Bjoerndal 2018 Nutr Metab (Lond) | 2018 | Bjørndal B, Alterås EK, Lindquist C, Svardal A, Skorve J, Berge RK (2018) Associations between fatty acid oxidation, hepatic mitochondrial function, and plasma acylcarnitine levels in mice. Nutr Metab (Lond) 15:10. | OXPHOS ET | F N ROX | Homogenate | Mouse | Liver |
Song 2018 Proc Natl Acad Sci U S A | 2018 | Song E, Ramos SV, Huang X, Liu Y, Botta A, Sung HK, Turnbull PC, Wheeler MB, Berger T, Wilson DJ, Perry CGR, Mak TW, Sweeney G (2018) Holo-lipocalin-2-derived siderophores increase mitochondrial ROS and impair oxidative phosphorylation in rat cardiomyocytes. Proc Natl Acad Sci U S A 115:1576-81. | LEAK OXPHOS ET | N S NS | Intact cells | Rat | Heart |
Chen 2018 Hum Mol Genet | 2018 | Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26. | OXPHOS ET | F N S DQ CIV NS | Isolated mitochondria | Human | Endothelial;epithelial;mesothelial cell Fibroblast |
Wuest 2018 Cell Metab | 2018 | Wüst S, Dröse S, Heidler J, Wittig I, Klockner I, Franko A, Bonke E, Günther S, Gärtner U, Boettger T, Braun T (2018) Metabolic maturation during muscle stem cell differentiation is achieved by miR-1/133a-mediated inhibition of the Dlk1-Dio3 mega gene cluster. Cell Metab 27:1026-39. | OXPHOS | N S CIV | Intact cells | Mouse | Skeletal muscle |
Becker 2018 EMBO Rep | 2018 | Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126. | LEAK OXPHOS ET | F N S NS ROX | Isolated mitochondria | Mouse | Liver Fat |
Chabi 2018 J Bioenerg Biomembr | 2018 | Chabi B, Fouret G, Lecomte J, Cortade F, Pessemesse L, Baati N, Coudray C, Lin L, Tong Q, Wrutniak-Cabello C, Casas F, Feillet-Coudray C (2018) Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition. J Bioenerg Biomembr 50:131-42. | LEAK OXPHOS | N S CIV NS | Homogenate Isolated mitochondria | Mouse | Skeletal muscle |
Scheiber 2018 J Cardiovasc Transl Res | 2018 | Scheiber D, Zweck E, Jelenik T, Horn P, Albermann S, Masyuk M, Boeken U, Saeed D, Kelm M Roden M, Szendroedi J, Westenfeld R (2018) Reduced myocardial mitochondrial ROS production in mechanically unloaded hearts. J Cardiovasc Transl Res 12:107-15. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Human | Heart |
Garcia-Roche 2018 Redox Biol | 2018 | García-Roche M, Casal A, Carriquiry M, Radi R, Celia Quijano C, Cassina A (2018) Respiratory analysis of coupled mitochondria in cryopreserved liver biopsies. Redox Biol 17:207-12. | LEAK OXPHOS ET | N NS ROX S | Permeabilized tissue | Rat Bovines | Liver |
Mikulas 2018 Dent Mater | 2018 | Mikulás K, Hermann P, Gera I, Komlódi T, Horváth G, Ambrus A, Tretter L (2018) Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e181. | OXPHOS ET | N S | Isolated mitochondria | Guinea pig | Nervous system |
Bouwkamp 2018 Neurol Genet | 2018 | Bouwkamp CG, Afawi Z, Fattal-Valevski A, Krabbendam IE, Rivetti S, Masalha R, Quadri M, Breedveld GJ, Mandel H, Tailakh MA, Beverloo HB, Stevanin G, Brice A, van IJcken WFJ, Vernooij MW, Dolga AM, de Vrij FMS, Bonifati V, Kushner SA (2018) ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia. Neurol Genet 4:e223. | OXPHOS ET | N | Isolated mitochondria | Human | |
Zhang 2018 J Gerontol A Biol Sci Med Sci | 2018 | Zhang X, Trevino MB, Wang M, Gardell SJ, Ayala JE, Han X, Kelly DP, Goodpaster BH, Vega RB, Coen PM (2018) Impaired mitochondrial energetics characterize poor early recovery of muscle mass following hind limb unloading in old mice. J Gerontol A Biol Sci Med Sci 73:1313-22. | LEAK OXPHOS | F N NS | Mouse | Skeletal muscle | |
Augustynek 2018 Int J Mol Sci | 2018 | Augustynek B, Koprowski P, Rotko D, Kunz WS, Szewczyk A, Kulawiak B (2018) Mitochondrial BK channel openers CGS7181 and CGS7184 exhibit cytotoxic properties. Int J Mol Sci 19. pii: E353. | OXPHOS | N | Isolated mitochondria | Rat | Nervous system |
Zimin 2018 Br J Anaesth | 2018 | Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32. | OXPHOS LEAK | N S ROX | Isolated mitochondria | Mouse | Nervous system |
Van Erp 2018 Sci Rep | 2018 | Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405. | OXPHOS ET | F N S NS | Isolated mitochondria | Rat | Liver Kidney |
Braz-Mota 2018 Sci Total Environ | 2018 | Braz-Mota S, Campos DF, MacCormack TJ, Duarte RM, Val AL, Almeida-Val VMF (2018) Mechanisms of toxic action of copper and copper nanoparticles in two Amazon fish species: Dwarf cichlid (Apistogramma agassizii) and cardinal tetra (Paracheirodon axelrodi). Sci Total Environ 630:1168-80. | LEAK OXPHOS ET | N NS ROX | Fishes | Lung;gill | |
Zhuang 2018 Thesis | 2018 | Zhuang Y (2018) Potential application of alternative oxidase (AOX) in neurodegenerative diseases. Master's Thesis p71. | OXPHOS | N S CIV ROX | Isolated mitochondria | Mouse | Nervous system |
Fouret 2018 Br J Nutr | 2018 | Fouret G, Gaillet S, Lecomte J, Bonafos B, Djohan F, Barea B, Badia E, Coudray C, Feillet-Coudray C (2018) 20-Week follow-up of hepatic steatosis installation and liver mitochondrial structure and activity and their interrelation in rats fed a high-fat-high-fructose diet. Br J Nutr 119:368-80. | OXPHOS | N NS | Rat | Liver | |
Hsiao 2018 Anal Biochem | 2018 | Hsiao CP, Hoppel C (2018) Analyzing mitochondrial function in human peripheral blood mononuclear cells. Anal Biochem 549:12-20. | OXPHOS ET | F N S DQ CIV NS ROX | Intact cells | Human | Blood cells |
Corrochano 2018 Hum Mol Genet | 2018 | Corrochano S, Blanco G, Williams D, Wettstein J, Simon M, Kumar S, Moir L, Agnew T, Stewart M, Landman A, Kotiadis VN, Duchen MR, Wackerhage H, Rubinsztein DC, Brown SDM, Acevedo-Arozena A (2018) A genetic modifier suggests that endurance exercise exacerbates Huntington's disease. Hum Mol Genet 27:1723-31. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Friederich-Persson 2018 Acta Physiol (Oxf) | 2018 | Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Kidney |
Petiz 2018 Chem Biol Interact | 2018 | Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Rat | Liver |
Meinild Lundby 2018 Acta Physiol (Oxf) | 2018 | Meinild Lundby AK, Jacobs RA, Gehrig S, de Leur J, Hauser M, Bonne TC, Flück D, Dandanell S, Kirk N, Kaech A, Ziegler U, Larsen S, Lundby C (2018) Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis. Acta Physiol (Oxf) 222, e12905. | OXPHOS LEAK ET | NS F N CIV | Permeabilized tissue | Human | Skeletal muscle |
Koit 2018 US Patent | 2018 | Koit A, Kaambre T (2018) Method for selecting patients responsive for cancer treatments. US Patent US20180017547A1. | OXPHOS | F N NS | Permeabilized cells | Human | |
Thrush 2018 Int J Obes (Lond) | 2018 | Thrush AB, Antoun G, Nikpay M, Patten DA, DeVlugt C, Mauger JF, Beauchamp BL, Lau P, Reshke R, Doucet É, Imbeault P, Boushel R, Gibbings D, Hager J, Valsesia A, Slack R, Al-Dirbashi OY, Dent R, McPherson R, Harper ME (2018) Diet-resistant obesity is characterized by a distinct plasma proteomic signature and impaired muscle fiber metabolism. Int J Obes (Lond) 42:353-62. | LEAK OXPHOS ET | F N CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Cejvanovic 2018 Free Radic Biol Med | 2018 | Cejvanovic V, Kjær LK, Bergholdt HKM, Torp-Pedersen A, Henriksen T, Weimann A, Ellervik C, Poulsen HE (2018) Iron induced RNA-oxidation in the general population and in mouse tissue. Free Radic Biol Med 115:127-35. | OXPHOS | N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Distefano 2018 J Cachexia Sarcopenia Muscle | 2018 | Distefano G, Standley RA, Zhang X, Carnero EA, Yi F, Cornnell HH, Coen PM (2018) Physical activity unveils the relationship between mitochondrial energetics, muscle quality, and physical function in older adults. J Cachexia Sarcopenia Muscle 9:279-94. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Docherty 2018 Atherosclerosis | 2018 | Docherty CK, Carswell A, Friel E, Mercer JR (2018) Impaired mitochondrial respiration in human carotid plaque atherosclerosis: A potential role for Pink1 in vascular smooth muscle cell energetics. Atherosclerosis 268:1-11. | OXPHOS | N CIV NS ROX | Permeabilized tissue | Human | Endothelial;epithelial;mesothelial cell |
Gonzalez-Freire 2018 Aging Cell | 2018 | Gonzalez-Freire M, Scalzo P, D'Agostino J, Moore ZA, Diaz-Ruiz A, Fabbri E, Zane A, Chen B, Becker KG, Lehrmann E, Zukley L, Chia CW, Tanaka T, Coen PM, Bernier M, de Cabo R, Ferrucci L (2018) Skeletal muscle ex vivo mitochondrial respiration parallels decline in vivo oxidative capacity, cardiorespiratory fitness, and muscle strength: the Baltimore longitudinal study of aging. Aging Cell 17. | LEAK OXPHOS | NS | Permeabilized tissue | Human | Skeletal muscle |
Chen 2018 Endocrinology | 2018 | Chen Y, McCommis KS, Ferguson D, Hall AM, Harris CA, Finck BN (2018) Inhibition of the mitochondrial pyruvate carrier by tolylfluanid. Endocrinology 159:609-21. | OXPHOS | N NS | Isolated mitochondria | Mouse | Fat |
Martins 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Martins EL, Ricardo JC, de-Souza-Ferreira E, Camacho-Pereira J, Ramos-Filho D, Galina A (2018) Rapid regulation of substrate use for oxidative phosphorylation during a single session of high intensity interval or aerobic exercises in different rat skeletal muscles. Comp Biochem Physiol B Biochem Mol Biol 217:40-50. | LEAK OXPHOS ET | F N NS ROX | Permeabilized tissue | Rat | Skeletal muscle |
Allard 2018 J Clin Endocrinol Metab | 2018 | Allard NAE, Schirris TJJ, Verheggen RJ, Russel FGM, Rodenburg RJ, Smeitink JAM, Thompson PD, Hopman MTE, Timmers S (2018) Statins affect skeletal muscle performance: evidence for disturbances in energy metabolism. J Clin Endocrinol Metab 103:75-84. | OXPHOS | F N S Gp CIV NS | Permeabilized tissue | Human | Skeletal muscle |
Dawson 2018 Acta Physiol (Oxf) | 2018 | Dawson NJ, Lyons SA, Henry DA, Scott GR (2018) Effects of chronic hypoxia on diaphragm function in deer mice native to high altitude. Acta Physiol (Oxf) 223:e13030. | LEAK OXPHOS | N CIV NS | Permeabilized tissue | Other mammals | Skeletal muscle |
Sirsat 2018 Comp Biochem Physiol A Mol Integr Physiol | 2018 | Sirsat SKG, Dzialowski EM (2018) Ontogeny of skeletal and cardiac muscle mitochondria oxygen fluxes in two breeds of chicken. Comp Biochem Physiol A Mol Integr Physiol 215:20-7. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Birds | Heart Skeletal muscle |
De Medeiros 2018 Biochim Biophys Acta | 2018 | de Medeiros WA, da Silva LA, Dall'Igna DM, Michels M, Manfredini A, Dos Santos Cardoso J, Constantino L, Scaini G, Vuolo F, Streck EL, Ritter C, Dal-Pizzol F (2018) N-acetylcysteine effects on a murine model of chronic critical limb ischemia. Biochim Biophys Acta 1864:454-63. | OXPHOS | F N NS | Rat | ||
Jang 2018 Intensive Care Med Exp | 2018 | Jang DH, MD, Khatri UG, Shortal BP, Kelly M, Lambert DS, Hardy K, Eckmann DM (2018) Alterations in mitochondrial respiration and reactive oxygen species in patients poisoned with carbon monoxide treated with hyperbaric oxygen. Intensive Care Med Exp 6:4. | LEAK OXPHOS ET | N S Gp CIV NS ROX | Permeabilized cells | Human | Blood cells |
Goncalves 2018 Life Sci | 2018 | Gonçalves DF, de Carvalho NR, Leite MB, Courtes AA, Hartmann DD, Stefanello ST, da Silva IK, Franco JL, Soares FAA, Dalla Corte CL (2018) Caffeine and acetaminophen association: Effects on mitochondrial bioenergetics. Life Sci 193:234-41. | LEAK OXPHOS | N S NS ROX | Homogenate | Mouse | Liver |
Ignatenko 2018 Nat Commun | 2018 | Ignatenko O, Chilov D, Paetau I, de Miguel E, Jackson CB, Capin G, Paetau A, Terzioglu M, Euro L, Suomalainen A (2018) Loss of mtDNA activates astrocytes and leads to spongiotic encephalopathy. Nat Commun 9:70. | OXPHOS ET | N CIV NS | Homogenate | Mouse | Nervous system |
Weisz 2018 Hum Mol Genet | 2018 | Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106. | OXPHOS ET LEAK | N S NS ROX | Isolated mitochondria | Drosophila | Skeletal muscle |
Oemer 2018 Proc Nat Acad Sci U S A | 2018 | Oemer G, Lackner L, Muigg K, Krumschnabel G, Watschinger K, Sailer S, Lindner H, Gnaiger E, Wortmann SB, Werner ER, Zschocke J, Keller MA (2018) The molecular structural diversity of mitochondrial cardiolipins. Proc Nat Acad Sci U S A 115:4158-63. | LEAK ROUTINE OXPHOS ET | F N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | HeLa |
Leckey 2018 FASEB J | 2018 | Leckey JJ, Hoffman NJ, Parr EB, Devlin BL, Trewin AJ, Stepto NK, Morton JP, Burke LM, Hawley JA (2018) High dietary fat intake increases fat oxidation and reduces skeletal muscle mitochondrial respiration in trained humans. FASEB J 32:2979-91. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Boutoual 2018 Sci Rep | 2018 | Boutoual R, Meseguer S, Villarroya M, Martín-Hernández E, Errami M, Martín MA, Casado M, Armengod ME (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARγ-UCP2-AMPK axis. Sci Rep 8:1163. | LEAK OXPHOS ET | F N S NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Smenes 2018 Interact Cardiovasc Thorac Surg | 2018 | Smenes BT, Bækkerud FH, Slagsvold KH, Hassel E, Wohlwend M, Pinho M, Høydal M, Wisløff U, Rognmo Ø, Wahba A (2018) Acute exercise is not cardioprotective and may induce apoptotic signalling in heart surgery: a randomized controlled trial. Interact Cardiovasc Thorac Surg 27:95-101. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized tissue | Human | Heart |
Woodman 2018 FASEB J | 2018 | Woodman AG, Mah R, Keddie D, Noble RMN, Panahi S, Gragasin FS, Lemieux H, Bourque SL (2018) Prenatal iron deficiency causes sex-dependent mitochondrial dysfunction and oxidative stress in fetal rat kidneys and liver. FASEB J 32:3254-63. | LEAK OXPHOS ET | N S CIV NS ROX | Homogenate | Rat | Liver Kidney |
Isohanni 2018 Neurogenetics | 2018 | Isohanni P, Carroll CJ, Jackson CB, Pohjanpelto M, Lönnqvist T, Suomalainen A (2018) Defective mitochondrial ATPase due to rare mtDNA m.8969G>A mutation-causing lactic acidosis, intellectual disability, and poor growth. Neurogenetics 19:49-53. | OXPHOS ET | N S CIV NS | Permeabilized cells | Human | Skeletal muscle Blood cells Fibroblast |
Silva 2018 Nat Cell Biol | 2018 | Silva J, Aivio S, Knobel PA, Bailey LJ, Casali A, Vinaixa M, Garcia-Cao I, Coyaud É, Jourdain AA, Pérez-Ferreros P, Rojas AM, Antolin-Fontes A, Samino-Gené S, Raught B, González-Reyes A, Ribas de Pouplana L, Doherty AJ, Yanes O, Stracker TH (2018) EXD2 governs germ stem cell homeostasis and lifespan by promoting mitoribosome integrity and translation. Nat Cell Biol 20:162-74. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Islet cell;pancreas;thymus | |
Mavroudis 2018 Eur J Cardiothorac Surg | 2018 | Mavroudis CD, Karlsson M, Ko T, Hefti M, Gentile JI, Morgan RW, Plyler R, Mensah-Brown KG, Boorady TW, Melchior RW, Rosenthal TM, Shade BC, Schiavo KL, Nicolson SC, Spray TL, Sutton RM, Berg RA, Licht DJ, Gaynor JW, Kilbaugh TJ (2018) Cerebral mitochondrial dysfunction associated with deep hypothermic circulatory arrest in neonatal swine. Eur J Cardiothorac Surg 54:162-68. | LEAK ET OXPHOS | N S CIV NS ROX | Homogenate | Pig | Nervous system |
Hoffmann 2018 Sci Rep | 2018 | Hoffmann C, Höckele S, Kappler L, Hrabĕ de Angelis M, Häring HU, Weigert C (2018) The effect of differentiation and TGFβ on mitochondrial respiration and mitochondrial enzyme abundance in cultured primary human skeletal muscle cells. Sci Rep 8:737. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Human | Skeletal muscle |
Teulier 2018 J Fish Biol | 2018 | Teulier L, Guillard L, Leon C, Romestaing C, Voituron Y (2018) Consequences of electroshock-induced narcosis in fish muscle: from mitochondria to swim performance. J Fish Biol 92:1805-18. | OXPHOS ET | N NS ROX | Intact cells | Fishes Zebrafish | Skeletal muscle |
Lund 2018 Acta Physiol (Oxf) | 2018 | Lund MT, Larsen S, Hansen M, Courraud J, Floyd AK, Støckel M, Helge JW, Dela F (2018) Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery. Acta Physiol (Oxf) 223:e13032. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Setz 2018 Hear Res | 2018 | Setz C, Benischke AS, Pinho Ferreira Bento AC, Brand Y, Levano S, Paech F, Leitmeyer K, Bodmer D (2018) Induction of mitophagy in the HEI-OC1 auditory cell line and activation of the Atg12/LC3 pathway in the organ of Corti. Hear Res 361:52-65. | OXPHOS ET | F N S NS ROX | Permeabilized cells | Mouse | Other cell lines |
Robach 2018 Scand J Med Sci Sports | 2018 | Robach P, Hansen J, Pichon A, Meinild Lundby AK, Dandanell S, Slettaløkken Falch G, Hammarström D, Pesta DH, Siebenmann C, Keiser S, Kérivel P, Whist JE, Rønnestad BR, Lundby C (2018) Hypobaric live high-train low does not improve aerobic performance more than live low-train low in cross-country skiers. Scand J Med Sci Sports 28:1636-52. | OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Cardinale 2018 Physiol Rep | 2018 | Cardinale DA, Gejl KD, Ørtenblad N, Ekblom B, Blomstrand E, Larsen FJ (2018) Reliability of maximal mitochondrial oxidative phosphorylation in permeabilized fibers from the vastus lateralis employing high-resolution respirometry. Physiol Rep 6. doi: 10.14814/phy2.13611. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Skeletal muscle |
Wu 2018 Adv Sci | 2018 | Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Mouse | Liver |
Jang 2018 J Med Toxicol | 2018 | Jang DH, Khatri UG, Mudan A, Love JS, Owiredu S, Eckmann DM (2018) Translational application of measuring mitochondrial functions in blood cells obtained from patients with acute poisoning. J Med Toxicol 14:144-51. | LEAK ROUTINE OXPHOS ET | N S Gp CIV NS ROX | Intact cells Permeabilized cells | Human | Blood cells |
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol | 2018 | Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse Rat | Skeletal muscle |
Shen 2018 Biosci Rep | 2018 | Shen NY, Ng SY, Toepp SL, Ljubicic V (2018) Protein arginine methyltransferase expression and activity during myogenesis. Biosci Rep 38. pii: BSR20171533. | OXPHOS | N NS | Permeabilized cells | Mouse | Skeletal muscle |
Kriel 2018 Sci Rep | 2018 | Kriel J, Mueller-Nedebock K, Maarman G, Mbizana S, Ojuka E, Klumperman B, Loos B (2018) Coordinated autophagy modulation overcomes glioblastoma chemoresistance through disruption of mitochondrial bioenergetics. Sci Rep 8:10348. | LEAK OXPHOS ET ROUTINE | N ROX | Permeabilized cells | Human | Nervous system Other cell lines |
Salin 2018 Integr Comp Biol | 2018 | Salin K, Villasevil EM, Anderson GJ, Selman C, Chinopoulos C, Metcalfe NB (2018) The RCR and ATP/O indices can give contradictory messages about mitochondrial efficiency. Integr Comp Biol 58:486-94. | LEAK OXPHOS | N S NS ROX | Homogenate | Fishes | Liver |
Cecatto 2018 J Cell Biochem | 2018 | Cecatto C, Wajner A, Vargas CR, Wajner SM, Amaral AU, Wajner M (2018) High vulnerability of the heart and liver to 3-hydroxypalmitic acid-induced disruption of mitochondrial functions in intact cell systems. J Cell Biochem 119:7678-86. | LEAK OXPHOS ET | N | Permeabilized cells Permeabilized tissue | Rat | Heart Nervous system Liver |
Vinel 2018 Nat Med | 2018 | Vinel C, Lukjanenko L, Batut A, Deleruyelle S, Pradere JP, Le Gonidec S, Dortignac A, Geoffre N, Pereira O, Karaz S, Lee U, Camus M, Chaoui K, Mouisel E, Bigot A, Mouly V, Vigneau M, Pagano AF, Chopard A, Pillard F, Guyonnet S, Cesari M, Burlet-Schiltz O, Pahor M, Feige JN, Vellas B, Valet P, Dray C (2018) The exerkine apelin reverses age-associated sarcopenia. Nat Med 24:1360-71. | OXPHOS | N S | Permeabilized tissue | Mouse | Skeletal muscle |
Pileggi 2018 Free Radic Biol Med | 2018 | Pileggi CA, Hedges CP, D'Souza RF, Durainayagam BR, Markworth JF, Hickey AJR, Mitchell CJ, Cameron-Smith D (2018) Exercise recovery increases skeletal muscle H2O2 emission and mitochondrial respiratory capacity following two-weeks of limb immobilization. Free Radic Biol Med 124:241-8. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Weber 2018 Int J Mol Sci | 2018 | Weber A, Klocker H, Oberacher H, Gnaiger E, Neuwirt H, Sampson N, Eder IE (2018) Succinate accumulation is associated with a shift of mitochondrial respiratory control and HIF-1α upregulation in PTEN negative prostate cancer cells. Int J Mol Sci 19:2129. | ROUTINE OXPHOS ET | F N S NS Other combinations ROX | Intact cells Permeabilized cells | Human | Genital |
Silaidos 2018 Biol Sex Differ | 2018 | Silaidos C, Pilatus U, Grewal R, Matura S, Lienerth B, Pantel J, Eckert GP (2018) Sex-associated differences in mitochondrial function in human peripheral blood mononuclear cells (PBMCs) and brain. Biol Sex Differ 9:34. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Permeabilized cells Intact cells | Human | Nervous system Blood cells |
Stein 2018 Cell Rep | 2018 | Stein CS, Jadiya P, Zhang X, McLendon JM, Abouassaly GM, Witmer NH, Anderson EJ, Elrod JW, Boudreau RL (2018) Mitoregulin: A lncRNA-encoded microprotein that supports mitochondrial supercomplexes and respiratory efficiency. Cell Rep 23:3710-20. | LEAK OXPHOS | F N | Permeabilized tissue | Human | Heart Skeletal muscle |
Goswami 2018 Biophys J | 2018 | Goswami I, Perry JB, Allen ME, Brown DA, von Spakovsky MR, Verbridge SS (2018) Influence of pulsed electric fields and mitochondria-cytoskeleton interactions on cell respiration. Biophys J 114:2951-64. | OXPHOS ET | N | Intact cells | Mouse | Other cell lines |
Cruz 2018 Chem Biol Interact | 2018 | Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52. | LEAK OXPHOS ET | N NS | Isolated mitochondria | Drosophila | |
Remor 2018 Mol Neurobiol | 2018 | Remor AP, da Silva RA, de Matos FJ, Glaser V, de Paula Martins R, Ghisoni K, da Luz Scheffer D, Andia DC, Portinho D, de Souza AP, de Oliveira PA, Prediger RD, Torres AI, Linhares RMM, Walz R, Ronsoni MF, Hohl A, Rafacho A, Aguiar AS Jr, De Paul AL, Latini A (2018) Chronic metabolic derangement-induced cognitive deficits and neurotoxicity are associated with REST inactivation. Mol Neurobiol 56:1539-57. | LEAK OXPHOS | N | Intact cells | Rat | Nervous system |
Durand 2018 Blood Purif | 2018 | Durand PY, Nicco C, Serteyn D, Attaf D, Edeas M (2018) Microbiota quality and mitochondrial activity link with occurrence of muscle cramps in hemodialysis patients using citrate dialysate: a pilot study. Blood Purif 46:301-8. | LEAK ROUTINE OXPHOS ET | S ROX | Intact cells | Human | Platelet Blood cells |
Logan 2018 Thesis | 2018 | Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Zebrafish | Skeletal muscle |
Rivas 2018 Am J Physiol Endocrinol Metab | 2018 | Rivas E, Herndon DN, Porter C, Meyer W, Suman OE. (2018) Short-term metformin and exercise training effects on strength, aerobic capacity, glycemic control, and mitochondrial function in children with burn injury.. Am J Physiol Endocrinol Metab. 314(3):E232-E240. | LEAK OXPHOS | Permeabilized tissue | Human | Skeletal muscle | |
Baaten 2018 Haematologica | 2018 | Baaten CCFMJ, Moenen FCJI, Henskens YMC, Swieringa F, Wetzels RJH, van Oerle R, Heijnen HFG, Ten Cate H, Holloway GP, Beckers EAM, Heemskerk JWM, van der Meijden PEJ (2018) Impaired mitochondrial activity explains platelet dysfunction in thrombocytopenic cancer patients undergoing chemotherapy. Haematologica 103:1557-67. | OXPHOS | N NS | Intact cells | Human | Blood cells Platelet |
Scott 2018 Integr Comp Biol | 2018 | Scott GR, Guo KH, Dawson NJ (2018) The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol 58:506-18. https://doi.org/10.1093/icb/icy056 | OXPHOS ET | N S CIV NS | Permeabilized tissue Isolated mitochondria | Mouse | Heart Skeletal muscle |
Cardinale 2018 Acta Physiol (Oxf) | 2018 | Cardinale DA, Larsen FJ, Jensen-Urstad M, Rullman E, Søndergaard H, Morales-Alamo D, Ekblom B, Calbet JAL, Boushel R (2018) Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity. Acta Physiol (Oxf) 225:e13110. | OXPHOS | F N NS | Permeabilized tissue Isolated mitochondria | Human | Skeletal muscle |
Kauppila 2018 Nucleic Acids Res | 2018 | Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69. | LEAK OXPHOS ET | N S NS | Isolated mitochondria | Mouse | |
Casal 2018 J Anim Sci | 2018 | Casal A, Garcia-Roche M, Navajas EA, Cassina A, Carriquiry M (2018) Hepatic mitochondrial function in Hereford steers with divergent residual feed intake phenotypes. J Anim Sci 96:4431-43. | LEAK OXPHOS ET | N S ROX | Intact cells | Bovines | Liver |
Scalzo 2018 Physiol Rep | 2018 | Scalzo RL, Knaub LA, Hull SE, Keller AC, Hunter K, Walker LA, Reusch JEB (2018) Glucagon-like peptide-1 receptor antagonism impairs basal exercise capacity and vascular adaptation to aerobic exercise training in rats. Physiol Rep 6:e13754. | LEAK OXPHOS ET | F NS Other combinations | Permeabilized tissue | Rat | Heart |
Sahl 2018 Anal Biochem | 2018 | Sahl RE, Morville T, Kraunsøe R, Dela F, Helge JW, Larsen S (2018) Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. Anal Biochem 556:119-24. | OXPHOS ET | N NS | Permeabilized cells Isolated mitochondria Intact cells | Human Mouse Saccharomyces cerevisiae | Skeletal muscle |
Jelenik 2018 Mol Metab | 2018 | Jelenik T, Dille M, Müller-Lühlhoff S, Kabra DG, Zhou Z, Binsch C, Hartwig S, Lehr S, Chadt A, Peters EMJ, Kruse J, Roden M, Al-Hasani H, Castañeda TR (2018) FGF21 regulates insulin sensitivity following long-term chronic stress. Mol Metab 16:126-38. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Mouse | Skeletal muscle |
Rundle 2018 Environ Sci Technol | 2018 | Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11. | LEAK OXPHOS ET | N ROX | Isolated mitochondria | Fishes | Liver |
Ounpuu 2018 Biochem Cell Biol | 2018 | Ounpuu L, Truu L, Shevchuk I, Chekulayev V, Klepinin A, Koit A, Tepp K, Puurand M, Rebane-Klemm E, Käämbre T (2018) Comparative analysis of the bioenergetics of human adenocarcinoma Caco-2 cell line and postoperative tissue samples from colorectal cancer patients. Biochem Cell Biol [Epub ahead of print]. | LEAK OXPHOS | N S CIV ROX | Permeabilized cells | Human | Endothelial;epithelial;mesothelial cell Other cell lines |
Lu 2018 Cell Rep | 2018 | Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52. | LEAK OXPHOS ET | N S NS ROX | Isolated mitochondria | Mouse | Heart |
Klepinin 2018 J Bioenerg Biomembr | 2018 | Klepinin A, Ounpuu L, Mado K, Truu L, Chekulayev V, Puurand M, Shevchuk I, Tepp K, Planken A, Kaambre T (2018) The complexity of mitochondrial outer membrane permeability and VDAC regulation by associated proteins. J Bioenerg Biomembr 50:339-54. | LEAK OXPHOS ET | N S NS ROX | Permeabilized cells | Mouse | Heart Neuroblastoma |
Wefers 2018 Proc Natl Acad Sci U S A | 2018 | Wefers J, van Moorsel D, Hansen J, Connell NJ, Havekes B, Hoeks J, van Marken Lichtenbelt WD, Duez H, Phielix E, Kalsbeek A, Boekschoten MV, Hooiveld GJ, Hesselink MKC, Kersten S, Staels B, Scheer FAJL, Schrauwen P (2018) Circadian misalignment induces fatty acid metabolism gene profiles and compromises insulin sensitivity in human skeletal muscle. Proc Natl Acad Sci U S A 115:7789-94. | OXPHOS ET | F N | Intact cells | Human | Skeletal muscle |
Ferri 2018 Eur J Appl Physiol | 2018 | Ferri A, Panariti A, Miserocchi G, Rocchetti M, Buoli Comani G, Rivolta I, Bishop DJ (2018) Tissue specificity of mitochondrial adaptations in rats after 4 weeks of normobaric hypoxia. Eur J Appl Physiol 118:1641-52. | LEAK OXPHOS | N | Permeabilized tissue | Rat | Heart Skeletal muscle |
Paech 2018b Toxicology | 2018 | Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23. | LEAK OXPHOS ET | N S DQ CIV ROX NS | Isolated mitochondria | Mouse | Liver |
Paech 2018a Toxicology | 2018 | Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44. | LEAK OXPHOS ET | N S DQ CIV ROX | Permeabilized cells Isolated mitochondria | Human Mouse | Liver Other cell lines |
Van der Pluijm 2018 Cardiovasc Res | 2018 | van der Pluijm I, Burger J, van Heijningen PM, IJpma A, van Vliet N, Milanese C, Schoonderwoerd K, Sluiter W, Ringuette LJ, Dekkers DHW, Que I, Kaijzel EL, Te Riet L, MacFarlane E, Das D, van der Linden R, Vermeij M, Demmers JA, Mastroberardino PG, Davis EC, Yanagisawa H, Dietz H, Kanaar R, Essers J (2018) Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation. Cardiovasc Res 114:1776-93. | OXPHOS | N S NS ROX | Homogenate | Mouse | Skeletal muscle |
Chou 2018 Int J Cardiol | 2018 | Chou CH, Fu TC, Tsai HH, Hsu CC, Wang CH, Wang JS (2018) High-intensity interval training enhances mitochondrial bioenergetics of platelets in patients with heart failure. Int J Cardiol 274:214-20. | LEAK ROUTINE OXPHOS ET | F N S NS ROX | Intact cells Permeabilized cells | Human | Platelet Blood cells |
Hafen 2018 J Appl Physiol (1985) | 2018 | Hafen PS, Preece CN, Sorensen JR, Hancock CR, Hyldahl RD (2018) Repeated exposure to heat stress induces mitochondrial adaptation in human skeletal muscle. J Appl Physiol (1985) 125:1447-55. | OXPHOS ET | N S NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Gam 2018 Acta Diabetol | 2018 | Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010. | LEAK OXPHOS | F N S NS | Isolated mitochondria | Human | Genital |
Barca 2018 Hum Mol Genet | 2018 | Barca E, Ganetzky RD, Potluri P, Juanola-Falgarona M, Gai X, Li D, Jalas C, Hirsch Y, Emmanuele V, Tadesse S, Ziosi M, Akman HO, Chung WK, Tanji K, McCormick E, Place E, Consugar M, Pierce EA, Hakonarson H, Wallace DC, Hirano M, Falk MJ (2018) USMG5 Ashkenazi Jewish founder mutation impairs mitochondrial complex V dimerization and ATP synthesis. Hum Mol Genet 27:3305-12. | LEAK ROUTINE OXPHOS ET | F N S DQ NS ROX | Permeabilized cells Intact cells | Human | Fibroblast |
Rodrigues 2018 Sci Rep | 2018 | Rodrigues APC, Camargo AF, Andjelkovic A, Jacobs HT, Oliveira MT (2018) Developmental arrest in Drosophila melanogaster caused by mitochondrial DNA replication defects cannot be rescued by the alternative oxidase. Sci Rep 8:10882. | OXPHOS | N CIV ROX | Homogenate Oxidase;biochemical oxidation | Drosophila | |
Dejos 2018 Sci Rep | 2018 | Dejos C, Kuny S, Han WH, Capel H, Lemieux H, Sauvé Y (2018) Photoreceptor-induced RPE phagolysosomal maturation defects in Stargardt-like Maculopathy (STGD3). Sci Rep 8:5944. | OXPHOS | N S CIV NS ROX | Homogenate | Mouse | Endothelial;epithelial;mesothelial cell |
Boutoual 2018 Scientific Reports | 2018 | Boutoual, R., Meseguer, S., Villarroya, M., Martin-Hernandez, E., Errami, M., Martin, M. A., Casado, M., and Armengod, M. E. (2018) Defects in the mitochondrial-tRNA modification enzymes MTO1 and GTPBP3 promote different metabolic reprogramming through a HIF-PPARgamma-UCP2-AMPK axis. Scientific reports 8, 1163 | LEAK ROUTINE OXPHOS ET | F S Gp | Permeabilized cells Intact cells | Human | Other cell lines Fibroblast |
Ost 2018 Curr Opin Clin Nutr Metab Care | 2018 | Ost M, Doerrier C, Gama-Perez P, Moreno-Gomez S (2018) Analysis of mitochondrial respiratory function in tissue biopsies and blood cells. Curr Opin Clin Nutr Metab Care 21:336-42. | LEAK ROUTINE OXPHOS ET | N S NS ROX | Permeabilized cells Permeabilized tissue Isolated mitochondria Intact cells | Blood cells Platelet Skeletal muscle Liver Fat | |
Tarpey 2018 Skelet Muscle | 2018 | Tarpey MD, Amorese AJ, Balestrieri NP, Ryan TE, Schmidt CA, McClung JM, Spangenburg EE (2018) Characterization and utilization of the flexor digitorum brevis for assessing skeletal muscle function. Skelet Muscle 8:14. | OXPHOS | N S CIV NS ROX | Mouse | Skeletal muscle | |
Komlodi 2018 Methods Mol Biol | 2018 | Komlodi T, Sobotka O, Krumschnabel G, Bezuidenhout N, Hiller E, Doerrier C, Gnaiger E (2018) Comparison of mitochondrial incubation media for measurement of respiration and hydrogen peroxide production. Methods Mol Biol 1782:137-55. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Permeabilized tissue | Human Mouse | Skeletal muscle HEK |
Monaco 2018b Diabetologia | 2018 | Monaco CMF, Hughes MC, Ramos SV, Varah NE, Lamberz C, Rahman FA, McGlory C, Tarnopolsky MA, Krause MP, Laham R, Hawke TJ, Perry CGR (2018) Altered mitochondrial bioenergetics and ultrastructure in the skeletal muscle of young adults with type 1 diabetes. Diabetologia 61:1411-23. | OXPHOS | N S Gp NS ROX | Permeabilized tissue | Human | Skeletal muscle |
Vatner 2018 Aging Cell | 2018 | Vatner DE, Zhang J, Oydanich M, Guers J, Katsyuba E, Yan L, Sinclair D, Auwerx J, Vatner SF (2018) Enhanced longevity and metabolism by brown adipose tissue with disruption of the regulator of G protein signaling 14. Aging Cell 17:e12751. | LEAK OXPHOS | N S NS | Intact cells | Mouse | Fat |
Chung 2018 J Exp Biol | 2018 | Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458. | LEAK OXPHOS ET | F N S CIV NS ROX | Isolated mitochondria | Fishes | Liver |
Rodrigues 2018 Free Radic Biol Med | 2018 | Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406. | LEAK ROUTINE OXPHOS ET | N S CIV NS ROX | Isolated mitochondria | Drosophila | |
Kappler 2018 Thesis | 2018 | Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181. | LEAK OXPHOS ET | F N S CIV NS ROX | Permeabilized cells Homogenate Isolated mitochondria | Human Mouse | Skeletal muscle Liver Other cell lines |
Cree-Green 2018 Diabetes | 2018 | Cree-Green M, Scalzo RL, Harrall K, Newcomer BR, Schauer IE, Huebschmann AG, McMillin S, Brown MS, Orlicky D, Knaub L, Nadeau KJ, Mcclatchey PM, Bauer TA, Regensteiner JG, Reusch JEB (2018) Supplemental oxygen improves in-vivo mitochondrial oxidative phosphorylation flux in sedentary obese adults with type 2 diabetes. Diabetes 67:1369-79. | LEAK OXPHOS ET | F N NS | Permeabilized tissue | Human | Skeletal muscle |
Flis 2018 Oxid Med Cell Longev | 2018 | Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice. Oxid Med Cell Longev 5940748. | LEAK OXPHOS | N | Isolated mitochondria | Mouse | Skeletal muscle |
Rodriguez-Nuevo 2018 EMBO J | 2018 | Rodríguez-Nuevo A, Díaz-Ramos A, Noguera E, Díaz-Sáez F, Duran X, Muñoz JP, Romero M, Plana N, Sebastián D, Tezze C, Romanello V, Ribas F, Seco J, Planet E, Doctrow SR, González J, Borràs M, Liesa M, Palacín M, Vendrell J, Villarroya F, Sandri M, Shirihai O, Zorzano A (2018) Mitochondrial DNA and TLR9 drive muscle inflammation upon Opa1 deficiency. EMBO J 37. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized tissue | Mouse | Skeletal muscle |
Bradley 2018 Biochim Biophys Acta | 2018 | Bradley RM, Bloemberg D, Aristizabal Henao JJ, Hashemi A, Mitchell AS, Fajardo VA, Bellissimo C, Mardian EB, Bombardier E, Paré MF, Moes KA, Stark KD, Tupling AR, Quadrilatero J, Duncan RE (2018) Lpaatδ/Agpat4 deficiency impairs maximal force contractility in soleus and alters fiber type in extensor digitorum longus muscle. Biochim Biophys Acta 1863:700-11. | LEAK OXPHOS ET | N S CIV NS | Permeabilized tissue | Mouse | Skeletal muscle |
Ahn 2018 Redox Biol | 2018 | Ahn B, Pharaoh G, Premkumar P, Huseman K, Ranjit R, Kinter M, Szweda L, Kiss T, Fulop G, Tarantini S, Csiszar A, Ungvari Z, Van Remmen H (2018) Nrf2 deficiency exacerbates age-related contractile dysfunction and loss of skeletal muscle mass. Redox Biol 17:47-58. | LEAK OXPHOS | N S CIV NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Perks 2018 Cell Rep | 2018 | Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42. | LEAK OXPHOS ET | N Gp S | Isolated mitochondria | Mouse | Heart |
Rajkumar 2018 Metabolism | 2018 | Rajkumar A, Liaghati A, Chan J, Lamothe G, Dent R, Doucet É, Rabasa-Lhoret R, Prud'homme D, Harper ME, Tesson F (2018) ACSL5 genotype influence on fatty acid metabolism: a cellular, tissue, and whole-body study. Metabolism 83:271-9. | OXPHOS ET | F N CIV NS | Permeabilized cells | Human Mouse | Skeletal muscle Other cell lines |
Zhang 2018 J Mol Cell Cardiol | 2018 | Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82. | LEAK ROUTINE OXPHOS ET | N S NS | Permeabilized cells Isolated mitochondria | Mouse | Heart |
Salin 2018 Funct Ecol | 2018 | Salin K, Villasevil EM, Anderson GJ, Auer SK, Selman C, Hartley RC, Mullen W, Chinopoulos C, Metcalfe NB (2018) Decreased mitochondrial metabolic requirements in fasting animals carry an oxidative cost. Funct Ecol DOI: 10.1111/1365-2435.13125. | LEAK OXPHOS | CIV NS ROX | Homogenate | Fishes | Liver |
Wen 2018 PLOS Pathog | 2018 | Wen JJ, Yin YW, Garg NJ (2018) PARP1 depletion improves mitochondrial and heart function in Chagas disease: Effects on POLG dependent mtDNA maintenance. PLOS Pathog 14:e1007065. | OXPHOS | N S NS | Permeabilized tissue | Mouse | Heart Other cell lines |
Bricambert 2018 Nat Commun | 2018 | Bricambert J, Alves-Guerra MC, Esteves P, Prip-Buus C, Bertrand-Michel J, Guillou H, Chang CJ, Vander Wal MN, Canonne-Hergaux F, Mathurin P, Raverdy V, Pattou F, Girard J, Postic C, Dentin R (2018) The histone demethylase Phf2 acts as a molecular checkpoint to prevent NAFLD progression during obesity. Nat Commun 9:2092. | LEAK OXPHOS ET | N S | Homogenate | Mouse | Liver |
Marini 2018 Proc Natl Acad Sci U S A | 2018 | Marini A, Rotblat B, Sbarrato T, Niklison-Chirou MV, Knight JRP, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G (2018) TAp73 contributes to the oxidative stress response by regulating protein synthesis. Proc Natl Acad Sci U S A 115:6219-24. | OXPHOS | N | Homogenate | Human | Kidney Lung;gill HEK |
Roy Chowdhury 2018 Mol Cell Neurosci | 2018 | Roy Chowdhury S, Djordjevic J, Thomson E, Smith DR, Albensi BC, Fernyhough P (2018) Depressed mitochondrial function and electron transport Complex II-mediated H2O2 production in the cortex of type 1 diabetic rodents. Mol Cell Neurosci 90:49-59. | OXPHOS ET | S | Mouse Rat | Nervous system | |
Carter 2018 J Physiol | 2018 | Carter HN, Kim Y, Erlich AT, Zarrin-Khat D, Hood DA (2018) Autophagy and mitophagy flux in young and aged skeletal muscle following chronic contractile activity. J Physiol 596:3567-84. | LEAK OXPHOS | N NS | Permeabilized tissue | Rat | Skeletal muscle |
Temelie 2018 Oxid Med Cell Longev | 2018 | Temelie M, Savu DI, Moisoi N (2018) Intracellular and intercellular signalling mechanisms following DNA damage are modulated by PINK1. Oxid Med Cell Longev 1391387. | OXPHOS ET | N NS | Permeabilized cells | Human Mouse | Nervous system Other cell lines Fibroblast |
Mkrtchyan 2018 Biochim Biophys Acta | 2018 | Mkrtchyan GV, Üçal M, Müllebner A, Dumitrescu S, Kames M, Moldzio R, Molcanyi M, Schaefer S, Weidinger A, Schaefer U, Hescheler J, Duvigneau JC, Redl H, Bunik VI, Kozlov AV (2018) Thiamine preserves mitochondrial function in a rat model of traumatic brain injury, preventing inactivation of the 2-oxoglutarate dehydrogenase complex. Biochim Biophys Acta 1859:925-31. | OXPHOS | N S | Homogenate | Rat | Nervous system |
Ravasz 2018 Biochim Biophys Acta | 2018 | Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24. | LEAK OXPHOS | F N DQ | Isolated mitochondria | Mouse | Liver |
Khamoui 2018 J Dev Orig Health Dis | 2018 | Khamoui AV, Desai M, Ross MG, Rossiter HB (2018) Sex-specific effects of maternal and postweaning high-fat diet on skeletal muscle mitochondrial respiration. J Dev Orig Health Dis 16:1-8. | LEAK OXPHOS ET | N NS ROX | Permeabilized tissue | Mouse | Skeletal muscle |
Stanford 2018 Cell Metab | 2018 | Stanford KI, Lynes MD, Takahashi H, Baer LA, Arts PJ, May FJ, Lehnig AC, Middelbeek RJW, Richard JJ, So K, Chen EY, Gao F, Narain NR, Distefano G, Shettigar VK, Hirshman MF, Ziolo MT, Kiebish MA, Tseng YH, Coen PM, Goodyear LJ (2018) 12,13-diHOME: an exercise-induced lipokine that increases skeletal muscle fatty acid uptake. Cell Metab 27:1111-20. | LEAK OXPHOS ET | F ROX | Permeabilized tissue | Human Mouse | Skeletal muscle |
Chung 2018 Integr Comp Biol | 2018 | Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM (2018) Mitochondria, temperature, and the pace of life. Integr Comp Biol 58:578-90. | OXPHOS | N | Permeabilized tissue Isolated mitochondria | Fishes | Heart Nervous system Liver |
Marinho 2018 Evid Based Complement Alternat Med | 2018 | Marinho PC, Vieira AB, Pereira PG, Rabelo K, Ciambarella BT, Nascimento ALR, Cortez E, Moura AS, Guimarães FV, Martins MA, Barquero G, Ferreira RN, de Carvalho JJ (2018) Capybara oil improves hepatic mitochondrial dysfunction, steatosis, and inflammation in a murine model of nonalcoholic fatty liver disease. Evid Based Complement Alternat Med 2018:4956079. | LEAK OXPHOS | Intact cells | Mouse | Liver |