Search results

• SUIT-028
  ! Respiratory state ...ate with type N substrates, N_''L'': Non-phosphorylating resting state with NADH-linked (type N) substrates pyruvate&glutamate&malate (PGM; withou
  4 KB (574 words) - 16:13, 14 April 2020
• Cardoso 2022 ESCI Bari
  ...getic fingerprinting with coupling and pathway control of coenzyme Q redox state and respiration in permeabilized HEK 293T cells. 56^th Annual Sci We characterised the Q redox state in pathway and coupling control using the Oroboros NextGen-O2k with the ele
  4 KB (520 words) - 14:41, 30 May 2022
• SUIT-021 Fluo mt D036
  ...f the ATP synthase. Since higher concentrations of Omy can decrease the ET state induced upon addition of uncoupler, the required concentration of Omy has t ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state.
  6 KB (834 words) - 14:07, 6 September 2021
• Chicco 2022 Abstract Bioblast
  ...(NS > S). However, in some types of mitochondria, rotenone added in the NS-state elicits a paradoxical increase in ''J''_O₂, revealing ::::# Department of Biomedical Sciences, Colorado State University, Fort Collins, Colorado, USA - adam.chicco@colostate.edu
  4 KB (625 words) - 08:33, 28 July 2022
• Cardoso 2022a EBEC
  ...of the Q-junction, respectively, impacts the relation between the Q redox state and O₂ flux in opposite directions. Therefore, our aim was to ch ...he NextGen-O2k with Q-Module to measure O₂ flux and the Q redox state simultaneously, using CoQ₂ as a probe [3]. Cryopreserved HEK 293
  4 KB (519 words) - 14:25, 23 August 2022
• Electron-transfer-pathway state
  |abbr=''ET-pathway state'' ...state]]s. [[Coupling-control state]]s require [[Electron-transfer-pathway state|ET-pathway competent states]], including oxygen supply. [[Categories of SUI
  15 KB (1,913 words) - 19:27, 25 August 2023
• Komlodi 2021 MitoFit Q
  ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. https://doi.org/10.26124/mitofit: ...omlodi_2021_MitoFit_Q.pdf Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria]
  5 KB (767 words) - 08:41, 8 January 2023
• Nemec 2018 MiP2018
  ...e (n=10) in seniors (28F/6M; age 66.5±4.3; BMI 26.4±4.0) on the functional state of the skeletal muscle mitochondria. ...ugh, regular exercise highly increased (p=0.003) electron transfer-pathway state (FNS_E) fueled by electrons from octanoyl oxidation, NADH-linked
  4 KB (476 words) - 00:16, 18 March 2019
• Succinate pathway
  ...that supports succinate-linked respiration (succinate-induced respiratory state; previously used nomenclature: CII-linked respiration; SRot; see [[Gnaiger The S-pathway control state is usually induced in mt-preparations by addition of succinate&rotenone. In
  8 KB (1,053 words) - 08:04, 30 March 2023
• SUIT-020 Fluo mt D033
  ...sed [[Mitochondrial membrane potential|mt-membrane potential]] in the LEAK state. ...tate| S]] and [[NADH Electron transfer-pathway state| N-]] pathway control state.
  5 KB (655 words) - 08:41, 30 September 2020
• Komlodi 2021 BEC Q
  ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. Bioenerg Commun 2021.3. https://d ...same manner as Q at Complexes CI, CII and CIII. The CoQ₂ redox state is monitored amperometrically with the working electrode, which is poised a
  6 KB (810 words) - 16:37, 21 January 2024
• SUIT-009 AmR mt D021
  ...in the LEAK state. Pyruvate (P) supports [[NADH Electron transfer-pathway state|NADH-pathway (N)]], and usually in the presence of ADP it does not increase ...s protocol is designed to evaluate RET in the S-linked pathway in the LEAK state, which is decreased by ADP due to reduction of the mt-membrane potential.
  5 KB (681 words) - 00:11, 13 April 2021
• Gnaiger 2009 Int J Biochem Cell Biol
  ...te in the matrix as substrates for NS-pathway control. This physiological state is reconsituted in mitochondrial preparations by external NS-substrate supp :::::* MitoPedia:» [[Electron-transfer-pathway state#Terminology: from CI- and CII-linked to N and S]]
  7 KB (975 words) - 13:46, 1 May 2024
• SUIT-009 AmR ce-pce D019
  ...s dramatically. Pyruvate (P) supports the [[NADH Electron transfer-pathway state|NADH-pathway]] and thus the convergent NS-pathway with little further effec ...s protocol is designed to evaluate RET in the S-linked pathway in the LEAK state, which is decreased by ADP due to reduction of the protonmotive force, ''pm
  5 KB (832 words) - 00:10, 13 April 2021
• Cardoso 2022 Abstract Bioblast
  ...nitoring of respiration together with NAD(P)H autofluorescence and Q-redox state [1] provides unique analytical and diagnostic power in the study of mitocho ...Rich PR, Gnaiger E (2021) Coupling and pathway control of coenzyme Q redox state and respiration in isolated mitochondria. https://doi.org/10.26124/bec:2021
  3 KB (463 words) - 08:34, 28 July 2022
• Szibor 2019 Biochim Biophys Acta Bioenerg
  ...reduces the Q pool almost entirely (>90 %) irrespective of the respiratory state. AOX enhances the forward electron transfer (FET) from CII thereby decreasi |topics=Redox state, Q-junction effect
  3 KB (458 words) - 12:35, 3 April 2021
• Van den Bergen 1994 Eur J Biochem
  ...ty of the cyanide-resistant pathway. The relation between rate and Q redox state for the external NADH dehydrogenase in potato callus mitochondria was found ...spiration rate is proportional to the redox state of the Q-pool. - ''redox state expressed as QH₂ fraction''
  7 KB (1,023 words) - 09:03, 16 July 2021
• Donnelly 2024 Redox Biol
  ...n isolated mitochondria, myotubes and exercising humans. Performing steady-state respirometry with isolated mitochondria we found that oxygen limitation of |topics=Calcium, mt-Membrane potential, Oxygen kinetics, Redox state
  3 KB (366 words) - 13:55, 1 May 2024
• Muller 2008 Biochem J
  ...ations of succinate and is thought not to occur when NAD is in the reduced state. However, very few studies have examined the rates of superoxide production
  3 KB (401 words) - 17:48, 16 January 2021
• Briston 2017 Sci Rep
  ...herapies. Here, we have investigated the impact of mitochondrial metabolic state on the probability and consequences of mPTP opening. Isolated mitochondria
  2 KB (324 words) - 12:54, 10 March 2020

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