Difference between revisions of "Tetraphenylphosphonium"
From Bioblast
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{{MitoPedia topics|type=Chemicals | {{MitoPedia topics|type=Chemicals | ||
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* [[O2k-TPP%2B_ISE-Module|O2k-TPP+ ISE-Module]] | :::: * [[O2k-TPP%2B_ISE-Module|O2k-TPP+ ISE-Module]] | ||
'''First TPP publication with HRR''' [[Brown 2011 Am J Physiol Regul Integr Comp Physiol]] | :::: '''First TPP publication with HRR''' [[Brown 2011 Am J Physiol Regul Integr Comp Physiol]] | ||
== TPP<sup>+</sup> inhibitory effect == | == TPP<sup>+</sup> inhibitory effect == | ||
{{Technical support integrated}} | {{Technical support integrated}} | ||
:::: For measurement of [[mitochondrial membrane potential]], the inhibitory concentration of the probe molecule should be evaluated on the activity of respiration [[MiPNet14.05]]. This side effect of TPP+ and TPMP+ (and various dyes) is frequently ignored. | |||
Revision as of 07:02, 6 May 2016
- high-resolution terminology - matching measurements at high-resolution
Tetraphenylphosphonium
Description
Tetraphenylphosphonium (TPP+). A molecular probe in conjunction with an ion selective electrode (ISE) for measuring the mitochondrial membrane potential.
See also: External unspecific binding of TPP+ and Internal unspecific binding of TPP+.
Abbreviation: TPP+
Reference: MiPNet14.05
- First TPP publication with HRR Brown 2011 Am J Physiol Regul Integr Comp Physiol
TPP+ inhibitory effect
MitoPedia O2k and high-resolution respirometry:
O2k-Open Support
- For measurement of mitochondrial membrane potential, the inhibitory concentration of the probe molecule should be evaluated on the activity of respiration MiPNet14.05. This side effect of TPP+ and TPMP+ (and various dyes) is frequently ignored.
