Wojtala 2014 Abstract MiP2014
| Proteomic analysis of mitochondrial complex I deficient mouse model - an impact of complex I deficiency on p66Shc-Ser36 phosphorylation pathway in NDUFS4-/- mice tissues. |
Link:
MiP2014, Book of Abstracts Open Access
Wojtala A, Koopman W, Willems PH, Smeitink JA, Duszynski J, Wieckowski MR (2014)
Event: MiP2014
Labels:
Stress:RONS; Oxidative Stress"RONS; Oxidative Stress" is not in the list (Cell death, Cryopreservation, Ischemia-reperfusion, Permeability transition, Oxidative stress;RONS, Temperature, Hypoxia, Mitochondrial disease) of allowed values for the "Stress" property. Organism: Mouse
Enzyme: Complex I
Coupling state: OXPHOS
MiP2014
Affiliation
1-Dep Biochem, Nencki Inst Experimental Biol, Warsaw, Poland; 2-Radbound Univ Medical Centre, Nijmegen, The Netherlands. - a.wojtala@nencki.gov.pl
References and acknowledgements
This work was supported by the Statutory Founding from Nencki Institute of Experimental Biology and Polish Ministry of Science and Higher Education grant W100/HFSC/2011.
- Distelmaier F, Koopmann WJ, van den Heuvel PL, Rodenburg RJ, Mayatepek E, Willems PH, Smeitink JA (2009) Mitochondrial complex I deficiency: from organelle dysfunction to clinical disease. Brain. 132: 833–42.
- Pinton P, Rimessi A, Marchi S, Orsini F, Migliaccio E, Giorgio M, Contursi C, Minucci S, Mantovani F, Wieckowski MR, Del Sal G, Pelicci PG, Rizzuto R (2007) Protein kinase C beta and prolyl isomerase 1 regulate mitochondrial effects of the life-span determinant p66Shc. Science 315: 659-63.
- Suski JM, Karkucinska-Wieckowska A, Lebiedzinska M, Giorgi C, Szczepanowska J, Szabadkai G, Duszynski J, Pronicki M, Pinton P, Wieckowski MR (2011) p66Shc aging protein in control of fibroblasts cell fate.
Int J Mol Sci 12: 5373-89.
