Semantic search

This page or action requires JavaScript to work, please enable JavaScript in your browser or use a browser where this is supported so that functionality can be served and is provided as requested. For further assistance, please have a look at the noscript help page.

Search Clear all entries

	Year	Reference	Coupling	Pathway	Preparation	Organism	Tissue;cell
Miotto 2016 Biochem J	2016	Miotto PM, Holloway GP (2016) In the absence of phosphate shuttling, exercise reveals the in vivo importance of creatine-independent mitochondrial ADP transport. Biochem J 473:2831-43.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Lashbrook 2016 Thesis	2016	Lashbrook M (2016) Functional responses of cardiac and skeletal muscle mitochondria to short-term obesity: are all obesities the same? Master's Thesis 63pp.	LEAK OXPHOS	F N NS	Permeabilized tissue Isolated mitochondria	Mouse Other mammals	Heart Skeletal muscle
Vevera 2016 Physiol Res	2016	Vevera J, Fišar Z, Nekovářová T, Vrablík M, Zlatohlávek L, Hroudová J, Singh N, Raboch J, Valeš K (2016) Statin-induced changes in mitochondrial respiration in blood platelets in rats and human with dyslipidemia. Physiol Res 65:777-88.	LEAK ROUTINE OXPHOS ET	N S NS Other combinations ROX	Intact cells Permeabilized cells	Human Rat	Blood cells Platelet
Moon 2016 J Biol Chem	2016	Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700.	LEAK OXPHOS	F N S NS Other combinations ROX	Isolated mitochondria	Mouse	Heart
Gehrig 2016 Orphanet J Rare Dis	2016	Gehrig SM, Mihaylova V, Frese S, Mueller SM, Ligon-Auer M, Spengler CM, Petersen JA, Lundby C, Jung HH (2016) Altered skeletal muscle (mitochondrial) properties in patients with mitochondrial DNA single deletion myopath. Orphanet J Rare Dis 11:105.	LEAK OXPHOS	F N S CIV NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
Li 2016 Sci Rep	2016	Li N, Guenancia C, Rigal E, Hachet O, Chollet P, Desmoulins L, Leloup C, Rochette L, Vergely C (2016) Short-term moderate diet restriction in adulthood can reverse oxidative, cardiovascular and metabolic alterations induced by postnatal overfeeding in mice. Sci Rep 6:30817	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Heart
Schoenenberger 2016 Cancer Res	2016	Schönenberger D, Harlander S, Rajski M, Jacobs RA, Lundby AK, Adlesic M, Hejhal T, Wild PJ, Lundby C, Frew IJ (2016) Formation of renal cysts and tumors in Vhl/Trp53-deficient mice requires HIF1α and HIF2α. Cancer Res 76:2025-36.	OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Nervous system
Anand 2016 PLOS ONE	2016	Anand R, Strecker V, Urbach J, Wittig I, Reichert AS (2016) Mic13 is essential for formation of crista junctions in mammalian cells. PLOS ONE 11:e0160258.	LEAK ROUTINE OXPHOS ET	N CIV NS Other combinations ROX	Permeabilized cells Intact cells		HEK
Tsai 2016 Sci Rep	2016	Tsai HH, Chang SC, Chou CH, Weng TP, Hsu CC, Wang JS (2016) Exercise training alleviates hypoxia-induced mitochondrial dysfunction in the lymphocytes of sedentary males. Sci Rep 6:35170.	LEAK ROUTINE OXPHOS ET	F N S NS Other combinations ROX	Permeabilized cells Intact cells	Human	Lymphocyte Blood cells
Kilbaugh 2016 Mitochondrion	2016	Kilbaugh TJ, Karlsson M, Duhaime AC, Hansson MJ, Elmer E, Margulies SS (2016) Mitochondrial response in a toddler-aged swine model following diffuse non-impact traumatic brain injury. Mitochondrion 26:19-25.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Kacso 2016 Biochem J	2016	Kacso G, Ravasz D, Doczi J, Németh B, Madgar O, Saada A, Ilin P, Miller C, Ostergaard E, Iordanov I, Adams D, Vargedo Z, Araki M, Araki K, Nakahara M, Ito H, Gál A, Molnár MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations. Biochem J 473:3463-85.	LEAK OXPHOS	F N Other combinations	Isolated mitochondria	Mouse	Heart Nervous system Liver
Rackham 2016 Cell Rep	2016	Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A (2016) Hierarchical RNA processing is required for mitochondrial ribosome assembly. Cell Rep 16:1874-90.	LEAK OXPHOS ET	N S CIV NS Other combinations	Isolated mitochondria	Mouse	Heart
Granata 2016 FASEB J	2016	Granata C, Oliveira RS, Little JP, Renner K, Bishop DJ (2016) Mitochondrial adaptations to high-volume exercise training are rapidly reversed after a reduction in training volume in human skeletal muscle. FASEB J 30:3413-23. https://doi.org/10.1096/fj.201500100R	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Liu 2016 EMBO Mol Med	2016	Liu J, Liang X, Zhou D, Lai L, Xiao L, Liu L, Fu T, Kong Y, Zhou Q, Vega RB, Zhu MS, Kelly DP, Gao X, Gan Z (2016) Coupling of mitochondrial function and skeletal muscle fiber type by a miR-499/Fnip1/AMPK circuit. EMBO Mol Med 8:1212-1228.	LEAK OXPHOS ET	N ROX	Permeabilized cells Permeabilized tissue	Mouse	Skeletal muscle
Porter 2016 Cell Metab	2016	Porter C, Herndon DN, Chondronikola M, Chao T, Annamalai P, Bhattarai N, Saraf MK, Capek KD, Reidy PT, Daquinag AC, Kolonin MG, Rasmussen BB, Borsheim E, Toliver-Kinsky T, Sidossis LS (2016) Human and mouse brown adipose tissue mitochondria have comparable UCP1 function. Cell Metab 24:246-55.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human Mouse	Skeletal muscle Fat
Pesta 2016 FASEB J	2016	Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Skeletal muscle
Bal 2016 J Biol Chem	2016	Bal NC, Maurya SK, Singh S, Wehrens XH, Periasamy M (2016) Increased reliance on muscle based thermogenesis upon acute minimization of brown adipose tissue function. J Biol Chem 291:17247-57.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Van Zutphen 2016 J Hepatol	2016	van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJA, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208.	LEAK OXPHOS ET	F N NS Other combinations	Isolated mitochondria	Rat	Liver
Saben 2016 Cell Rep	2016	Saben JL, Boudoures AL, Asghar Z, Thompson A, Drury A, Zhang W, Chi M, Cusumano A, Scheaffer S, Moley KH (2016) Maternal metabolic syndrome programs mitochondrial dysfunction via germline changes across three generations. Cell Rep 16:1-8.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Most 2016 Am J Clin Nutr	2016	Most J, Timmers S, Warnke I, Jocken JW, van Boekschoten M, de Groot P, Bendik I, Schrauwen P, Goossens GH, Blaak EE (2016) Combined epigallocatechin-3-gallate and resveratrol supplementation for 12 wk increases mitochondrial capacity and fat oxidation, but not insulin sensitivity, in obese humans: a randomized controlled trial. Am J Clin Nutr 104:215-27.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Gregg 2016 Diabetes	2016	Gregg T, Poudel C, Schmidt BA, Dhillon RS, Sdao SM, Truchan NA, Baar EL, Fernandez LA, Denu JM, Eliceiri KW, Rogers JD, Kimple ME, Lamming DW, Merrins MJ (2016) Pancreatic β cells from mice offset age-associated mitochondrial deficiency with reduced K_ATP channel activity. Diabetes 65:2700-10.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Human Mouse	Islet cell;pancreas;thymus Other cell lines
Richman 2016 Nat Commun	2016	Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart Liver
Lemieux 2016 Mitochondrion	2016	Lemieux H, Boemer F, van Galen G, Serteyn D, Amory H, Baise E, Cassart D, van Loon G, Marcillaud-Pitel C, Votion DM (2016) Mitochondrial function is altered in horse atypical myopathy. Mitochondrion 30:35-41.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Thomas 2016 Neurodegeneration Therapeutics	2016	Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Rat	Nervous system
Price 2016 J Thermal Biol	2016	Price ER, Sirsat TS, Sirsat SKG, Kang G, Keereetaweep J, Aziz M, Chapman KD, Dzialowski EM (2016) Thermal acclimation in American alligators: Effects of temperature regime on growth rate, mitochondrial function, and membrane composition. J Thermal Biol p11.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Reptiles	Heart Skeletal muscle
Ryan 2016 Diabetes	2016	Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68.	LEAK OXPHOS ET	N S CIV Other combinations ROX	Isolated mitochondria	Mouse	Skeletal muscle
Gariani 2016 Hepatology	2016	Gariani K, Menzies KJ, Ryu D, Wegner CJ, Wang X, Ropelle ER, Moullan N, Zhang H, Perino A, Lemos V, Kim B, Park YK, Piersigilli A, Pham TX, Yang Y, Ku SC, Koo SI, Fomitchova A, Cantó C, Schoonjans K, Sauve AA, Lee JY, Auwerx J (2016) Eliciting the mitochondrial unfolded protein response via NAD+ repletion reverses fatty liver disease. Hepatology 63:1190-204.	OXPHOS	N S	Permeabilized tissue	Mouse	Liver
Layec 2016 Am J Physiol Endocrinol Metab	2016	Layec G, Gifford JR, Trinity JD, Hart CR, Garten RS, Park SY, Le Fur Y, Jeong EK, Richardson RS (2016) Accuracy and precision of quantitative 31P-MRS measurements of human skeletal muscle mitochondrial function. Am J Physiol Endocrinol Metab 311:E358-66.	LEAK OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Edgett 2016 Exp Physiol	2016	Edgett BA, Hughes MC, Matusiak JB, Perry CG, Simpson CA, Gurd BJ (2016) SIRT3 gene expression but not SIRT3 subcellular localization is altered in response to fasting and exercise in human skeletal muscle. Exp Physiol 101:1101-13.	OXPHOS	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Gilliam 2016 Am J Physiol Endocrinol Metab	2016	Gilliam LA, Lark DS, Reese LR, Torres MJ, Ryan TE, Lin CT, Cathey BL, Neufer PD (2016) Targeted overexpression of mitochondrial catalase protects against cancer chemotherapy-induced skeletal muscle dysfunction. Am J Physiol Endocrinol Metab 311:E293-301.	LEAK OXPHOS	F N NS Other combinations	Permeabilized tissue	Mouse	Skeletal muscle
Sobotka 2016 J Bioenerg Biomembr	2016	Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.	LEAK OXPHOS	N S CIV	Intact cells Permeabilized cells Homogenate Isolated mitochondria	Mouse Rat	Liver
Dias 2016 Neurobiol Aging	2016	Dias C, Lourenço CF, Ferreiro E, Barbosa RM, Laranjinha J, Ledo A (2016) Age-dependent changes in the glutamate-nitric oxide pathway in the hippocampus of the triple transgenic model of Alzheimer's disease: implications for neurometabolic regulation. Neurobiol Aging 46:84-95.	LEAK ET	N S ROX	Permeabilized tissue	Mouse	Nervous system
Barth 2016 Thesis	2016	Barth C (2016) Effekte einer intermittierenden Hyperoxie auf die mitochondriale Atmung in Alveolarmakrophagen. Dissertation p69.	LEAK ROUTINE OXPHOS	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Lung;gill Macrophage-derived
Christensen 2016 J Appl Physiol (1985)	2016	Christensen PM, Jacobs RA, Bonne T, Flück D, Bangsbo J, Lundby C (2016) A short period of high-intensity interval training improves skeletal muscle mitochondrial function and pulmonary oxygen uptake kinetics. J Appl Physiol (1985) 120:1319-27.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
Ruas 2016 PLOS ONE	2016	Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF (2016) Underestimation of the maximal capacity of the mitochondrial electron transport system in oligomycin-treated cells. PLOS ONE 11:e0150967.	LEAK OXPHOS ET	N	Intact cells Permeabilized cells Isolated mitochondria	Human Rat	Nervous system Genital Other cell lines
Viola 2016 JACC: Basic to Translational Science	2016	Viola HM, Johnstone VPA, Szappanos HC, Richman TR, Tsoutsman T, Filipovska A, Semsarian C, Seidman JG, Seidman CE, Hool LC (2016) The role of the L-type Ca²⁺ channel in altered metabolic activity in a murine model of hypertrophic cardiomyopathy. JACC: Basic to Translational Science 1: 61–72.	OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart
Chabi 2016 Exp Gerontol	2016	Chabi B, Pauly M, Carillon J, Carnac G, Favier FB, Fouret G, Bonafos B, Vanterpool F, Vernus B, Coudray C, Feillet-Coudray C, Bonnieu Z, Lacan D, Koechlin-Ramonatxo C (2016) Protective effect of myostatin gene deletion on aging-related muscle metabolic decline. Exp Gerontol 78:23-31.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Skeletal muscle
Ehinger 2016 Mov Disord	2016	Ehinger JK, Morota S, Hansson MJ, Gesine P, Elmér E (2016) Mitochondrial respiratory function in peripheral blood cells from Huntington’s disease patients. Mov Disord doi:10.1002/mdc3.12308.	LEAK ROUTINE OXPHOS ET	N S CIV NS Other combinations ROX	Permeabilized cells Intact cells	Human	Blood cells Lymphocyte Platelet
Baeder 2016 Int J Dent	2016	Baeder AC, Napa K, Richardson ST, Taylor OJ, Andersen SG, Wilcox SH, Winden DR, Reynolds PR, Bikman BT (2016) Oral gingival cell cigarette smoke exposure induces muscle cell metabolic disruption. Int J Dent 2016:2763160.	LEAK OXPHOS ET	N NS ROX	Permeabilized cells	Mouse	Skeletal muscle
Newell 2016 Physiol Entomol	2016	Newell C, Kane CL, Kane DC (2016) Mitochondrial substrate specificity in beetle flight muscle: assessing respiratory oxygen flux in small samples from Dermestes maculatus and Tenebrio molitor. Physiol Entomol p7.	OXPHOS	F N Gp Other combinations	Permeabilized tissue	Hexapods	Skeletal muscle
Sirsat 2016 Biol Open	2016	Sirsat SK, Sirsat TS, Price ER, Dzialowski EM (2016) Post-hatching development of mitochondrial function, organ mass and metabolic rate in two ectotherms, the American alligator (Alligator mississippiensis) and the common snapping turtle (Chelydra serpentina). Biol Open 5:443-51.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Reptiles	Heart Skeletal muscle
Salin 2016 J Exp Biol	2016	Salin K, Auer SK, Anderson GJ, Selman C, Metcalfe NB (2016) Inadequate food intake at high temperatures is related to depressed mitochondrial respiratory capacity. J Exp Biol 219:1356-62.	LEAK OXPHOS	N S CIV NS Other combinations ROX	Permeabilized tissue	Fishes	Skeletal muscle Liver
Alleman 2016 Am J Physiol Heart Circ Physiol	2016	Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA (2016) Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol 310:H1360-70.	LEAK OXPHOS	N NS	Isolated mitochondria	Rat	Heart
Chu 2016 World J Gastroenterol	2016	Chu MJ, Premkumar R, Hickey AJ, Jiang Y, Delahunt B, Phillips AR, Bartlett A (2016) Steatotic livers are susceptible to normothermic ischemia-reperfusion injury from mitochondrial Complex-I dysfunction. World J Gastroenterol 22:4673-84.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Liver
Zabielski 2016 Diabetes	2016	Zabielski P, Lanza IR, Gopala S, Holtz Heppelmann CJ, Bergen HR 3rd, Dasari S, Nair KS (2016) Altered skeletal muscle mitochondrial proteome as the basis of disruption of mitochondrial function in diabetic mice. Diabetes 65:561-73.	LEAK OXPHOS ET	F N S NS ROX	Permeabilized cells	Mouse	Skeletal muscle
Chang 2016 Transl Res	2016	Chang JC, Wu SL, Liu KH, Chen YH, Chuang CS, Cheng FC, Su HL, Wei YH, Kuo SJ, Liu CS (2016) Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity. Transl Res 170:40-56.	LEAK OXPHOS ET	N	Isolated mitochondria	Rat	Nervous system Other cell lines
Lores-Arnaiz 2016 Neurochem Res	2016	Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63.	LEAK ROUTINE OXPHOS ET	N S	Isolated mitochondria Intact cells	Mouse	Nervous system
Amaral 2016 J Neurochem	2016	Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Rat	Nervous system
LaBarge 2016 FASEB J	2016	LaBarge SA, Migdal CW, Buckner EH, Okuno H, Gertsman I, Stocks B, Barshop BA, Nalbandian SR, Philp A, McCurdy CE, Schenk S (2016) p300 is not required for skeletal muscle metabolic adaptation to endurance exercise training. FASEB J 30:1623-33.	LEAK OXPHOS ET	F N NS ROX S Other combinations	Permeabilized tissue	Mouse	Skeletal muscle
Pamenter 2016 Biol Lett	2016	Pamenter ME, Gomez CR, Richards JG, Milsom WK (2016) Mitochondrial responses to prolonged anoxia in brain of red-eared slider turtles. Biol Lett 12. pii: 20150797.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized tissue	Reptiles	Nervous system
Soendergaard 2016 Eur J Sport Sci	2016	Søndergård SD, Dela F, Helge JW, Larsen S (2016) Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle. Eur J Sport Sci 16:801-7.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Wolff 2016 J Evol Biol	2016	Wolff JN, Pichaud N, Camus MF, Côté G, Blier PU, Dowling DK (2016) Evolutionary implications of mitochondrial genetic variation: mitochondrial genetic effects on OXPHOS respiration and mitochondrial quantity change with age and sex in fruit flies. J Evol Biol 29:736-47.	LEAK OXPHOS ET	N Gp CIV Other combinations ROX	Permeabilized tissue	Drosophila	Skeletal muscle
Sparks 2016 Diabetologia	2016	Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue Isolated mitochondria	Human Mouse Rat	Skeletal muscle Other cell lines
Reijne 2016 PLOS ONE	2016	Reijne AC, Ciapaite J, van Dijk TH, Havinga R, van der Zee EA, Groen AK, Reijngoud DJ, Bakker BM, van Dijk G (2016) Whole-body vibration partially reverses aging-induced increases in visceral adiposity and hepatic lipid storage in mice. PLOS ONE 11:e0149419.	LEAK OXPHOS	F N Other combinations	Isolated mitochondria	Mouse	Skeletal muscle Liver
Du 2016 J Exp Biol	2016	Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Fishes	Liver
Keller 2016 Oxid Med Cell Longev	2016	Keller AC, Knaub LA, McClatchey PM, Connon CA, Bouchard R, Miller MW, Geary KE, Walker LA, Klemm DJ, Reusch JE (2016) Differential mitochondrial adaptation in primary vascular smooth muscle cells from a diabetic rat model. Oxid Med Cell Longev 2016:8524267.	LEAK OXPHOS ET	N NS	Permeabilized cells	Rat	Endothelial;epithelial;mesothelial cell
Sirsat 2016 J Comp Physiol B	2016	Sirsat SK, Sirsat TS, Crossley JL, Sotherland PR, Dzialowski EM (2016) The 12-day thermoregulatory metamorphosis of Red-winged Blackbirds (Agelaius phoeniceus). J Comp Physiol B 186:651-663.	LEAK OXPHOS	N	Permeabilized tissue	Birds	Skeletal muscle
Lim 2016 FASEB J	2016	Lim SC, Hroudová J, Van Bergen NJ, Lopez Sanchez MI, Trounce IA, McKenzie M (2016) Loss of mitochondrial DNA-encoded protein ND1 results in disruption of complex I biogenesis during early stages of assembly. FASEB J 30:2236-48.	OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Other cell lines
Wang 2016 Toxicol Sci	2016	Wang L, Espinoza HM, MacDonald JW, Bammler TK, Williams CR, Yeh A, Louie KW, Marcinek DJ, Gallagher EP (2016) Olfactory Transcriptional Analysis of Salmon Exposed to Mixtures of Chlorpyrifos and Malathion Reveal Novel Molecular Pathways of Neurobehavioral Injury. Toxicol Sci 149:145-57.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Endothelial;epithelial;mesothelial cell
Farsijani 2016 J Clin Invest	2016	Farsijani NM, Liu Q, Kobayashi H, Davidoff O, Sha F, Fandrey J, Ikizler TA, O'Connor PM, Haase VH (2016) Renal epithelium regulates erythropoiesis via HIF-dependent suppression of erythropoietin. J Clin Invest 126:1425-37.	LEAK OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Nervous system
Boutant 2016 Cell Rep	2016	Boutant M, Kulkarni SS, Joffraud M, Raymond F, Métairon S, Descombes P, Cantó C (2016) SIRT1 gain of function does not mimic or enhance the adaptations to intermittent fasting. Cell Rep 14:2068-75.	OXPHOS ET	N NS	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver Fat
Cannon 2016 Lung	2016	Cannon DT, Liu J, Sakurai R, Rossiter HB, Rehan VK (2016) Impaired lung mitochondrial respiration following perinatal nicotine exposure in rats. Lung 194:325-8.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Rat	Lung;gill
Hamilton 2016 Am J Physiol Heart Circ Physiol	2016	Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80.	LEAK OXPHOS	F N S NS Other combinations ROX	Permeabilized tissue Isolated mitochondria	Mouse	Heart
Vinnakota 2016a Biophys J	2016	Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA (2016) Feedback regulation and time hierarchy of oxidative phosphorylation in cardiac mitochondria. Biophys J 110:972-80.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Schoepf 2016 FEBS J	2016	Schöpf B, Schäfer G, Weber A, Talasz H, Eder IE, Klocker H, Gnaiger E (2016) Oxidative phosphorylation and mitochondrial function differ between human prostate tissue and cultured cells. https://doi.org/10.1111/febs.13733	LEAK OXPHOS ET	F N S NS Other combinations ROX	Permeabilized cells Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell Genital Other cell lines Fibroblast
Vinnakota 2016b Biophys J	2016	Vinnakota KC, Singhal A, Van den Bergh F, Bagher-Oskouei M, Wiseman RW, Beard DA (2016) Open-loop control of oxidative phosphorylation in skeletal and cardiac muscle mitochondria by Ca²⁺. Biophys J 110:954-61.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart Skeletal muscle
Leucci 2016 Nature	2016	Leucci E, Vendramin R, Spinazzi M, Laurette P, Fiers M, Wouters J, Radaelli E, Eyckerman S, Leonelli C, Vanderheyden K, Rogiers A, Hermans E, Baatsen P, Aerts S, Amant F, Van Aelst S, van den Oord J, de Strooper B, Davidson I, Lafontaine DL, Gevaert K, Vandesompele J, Mestdagh P, Marine JC (2016) Melanoma addiction to the long non-coding RNA SAMMSON. Nature 531:518-22.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Li 2016 J Appl Physiol (1985)	2016	Li C, White SH, Warren LK, Wohlgemuth SE (2016) Effects of aging on mitochondrial function in skeletal muscle of quarter horses. J Appl Physiol (1985) 121:299-311.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Power 2016 Am J Physiol Heart Circ Physiol	2016	Power AS, Pham T, Loiselle DS, Crossman DH, Ward ML, Hickey AJ (2016) Impaired ADP channeling to mitochondria and elevated reactive oxygen species in hypertensive hearts. https://doi.org/10.1152/ajpheart.00050.2016	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue Homogenate	Rat	Heart
Munro 2016 Free Radic Biol Med	2016	Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H₂O₂ consumption pathways in muscle mitochondria: Involvement in H₂O₂ metabolism and consequence to H₂O₂ efflux assays. Free Radic Biol Med 96:334-46.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Skeletal muscle
Morad 2016 J Lipid Res	2016	Morad SA, Ryan TE, Neufer PD, Zeczycki TN, Davis TS, MacDougall MR, Fox TE, Tan SF, Feith DJ, Loughran TP Jr, Kester M, Claxton DF, Barth BM, Deering TG, Cabot MC (2016) Ceramide-tamoxifen regimen targets bioenergetic elements in acute myelogenous leukemia. J Lipid Res 57:1231-42.	LEAK OXPHOS	N S NS	Permeabilized cells	Human	Blood cells Other cell lines
Yavari 2016 Cell Metab	2016	Yavari A, Stocker CJ, Ghaffari S, Wargent ET, Steeples V, Czibik G, Pinter K, Bellahcene M, Woods A, Martinez de Morentin PB, Cansell C, Lam BY, Chuster A, Petkevicius K, Nguyen-Tu MS, Martinez-Sanchez A, Pullen TJ, Oliver PL, Stockenhuber A, Nguyen C, Lazdam M, O'Dowd JF, Harikumar P, Toth M, Beall C, Kyriakou T, Parnis J, Sarma D, Katritsis G, Wortmann DD, Harper AR, Brown LA, Willows R, Gandra S, Poncio V, de Oliveira Figueiredo MJ, Qi NR, Peirson SN, McCrimmon RJ, Gereben B, Tretter L, Fekete C, Redwood C, Yeo GS, Heisler LK, Rutter GA, Smith MA, Withers DJ, Carling D, Sternick EB, Arch JR, Cawthorne MA, Watkins H, Ashrafian H (2016) Chronic activation of γ2 AMPK induces obesity and reduces β cell function. Cell Metab 23:821-36.	LEAK OXPHOS ET	N NS ROX	Homogenate	Mouse	Nervous system
Distefano 2016 J Gerontol A Biol Sci Med Sci	2016	Distefano G, Standley RA, Dubé JJ, Carnero EA, Ritov VB, Stefanovic-Racic M, Toledo FG, Piva SR, Goodpaster BH, Coen PM (2016) Chronological age does not influence ex-vivo mitochondrial respiration and quality control in skeletal muscle. J Gerontol A Biol Sci Med Sci 72:535-42.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Reynolds 2016 Am J Physiol Endocrinol Metab	2016	Reynolds MS, Hancock CR, Ray JD, Kener KB, Draney C, Garland K, Hardman J, Bikman BT, Tessem JS (2016) β-cell deletion of Nr4a1 and Nr4a3 nuclear receptors impedes mitochondrial respiration and insulin secretion. Am J Physiol Endocrinol Metab 311:E186-201.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus
Piwonska 2016 Acta Neurobiol Exp (Wars)	2016	Piwońska M, Szewczyk A, Schröder UH, Reymann KG, Bednarczyk P (2016) Effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. Acta Neurobiol Exp (Wars) 76:20-31.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Nervous system
Snook 2016 Am J Physiol Regul Integr Comp Physiol	2016	Snook LA, MacPherson RE, Monaco CM, Frendo-Cumbo S, Castellani L, Peppler WT, Anderson ZG, Buzelle SL, LeBlanc PJ, Holloway GP, Wright DC (2016) Prior exercise training blunts short term highfat diet induced weight gain. Am J Physiol Regul Integr Comp Physiol 311:R315-24.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Fat
Kimball 2016 Thesis	2016	Kimball RL (2016) The role of hypoxia on pyruvate kinase M2, mammalian target of rapamycin, mitochondrial function, and cell invasion in the trophoblast. Master Thesis p55.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Genital Other cell lines
Tunholi 2016 J Invertebr Pathol	2016	Tunholi VM, Tunholi-Alves VM, Santos AT, Garcia Jda S, Maldonado A Jr, da-Silva WS, Rodrigues Mde L, Pinheiro J (2016) Evaluation of the mitochondrial system in the gonad-digestive gland complex of Biomphalaria glabrata (Mollusca, Gastropoda) after infection by Echinostoma paraensei (Trematoda, Echinostomatidae). J Invertebr Pathol 136:136-41.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Molluscs	Genital
Scialo 2016 Cell Metab	2016	Scialò F, Sriram A, Fernández-Ayala D, Gubina N, Lõhmus M, Nelson G, Logan A, Cooper HM, Navas P, Enríquez JA, Murphy MP, Sanz A (2016) Mitochondrial ROS produced via reverse electron transport extend animal lifespan. Cell Metab 23:725-34.	LEAK OXPHOS	N Gp CIV Other combinations ROX	Homogenate	Drosophila
Gifford 2016 J Physiol	2016	Gifford JR, Garten RS, Nelson AD, Trinity JD, Layec G, Witman MA, Weavil JC, Mangum T, Hart C, Etheredge C, Jessop J, Bledsoe A, Morgan DE, Wray DW, Richardson RS (2016) Symmorphosis and skeletal muscle V_O₂max: in vivo and in vitro measures reveal differing constraints in the exercise-trained and untrained human. https://doi.org/10.1113/JP271229	OXPHOS	N NS	Permeabilized cells	Human	Skeletal muscle
Viola 2016 J Physiol	2016	Viola H, Johnstone V, Szappanos HC, Richman T, Tsoutsman T, Filipovska A, Semsarian C, Hool L (2016) The L-type Ca²⁺ channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy. J Physiol 594:4051-70.		N S CIV	Isolated mitochondria	Mouse	Heart
Sadhukhan 2016 Proc Natl Acad Sci U S A	2016	Sadhukhan S, Liu X, Ryu D, Nelson OD, Stupinski JA, Li Z, Chen W, Zhang S, Weiss RS, Locasale JW, Auwerx J, Lin H (2016) Metabolomics-assisted proteomics identifies succinylation and SIRT5 as important regulators of cardiac function. Proc Natl Acad Sci U S A 113:4320-5.	LEAK OXPHOS	F N	Permeabilized tissue	Mouse	Heart
Bonifacio 2016 Arch Toxicol	2016	Bonifacio A, Mullen PJ, Mityko IS, Navegantes LC, Bouitbir J, Krähenbühl S (2016) Simvastatin induces mitochondrial dysfunction and increased atrogin-1 expression in H9c2 cardiomyocytes and mice in vivo. Arch Toxicol 90:203-15. doi: 10.1007/s00204-014-1378-4	LEAK OXPHOS ET	N S DQ CIV NS	Permeabilized cells Permeabilized tissue Intact cells	Rat	Heart
Bai 2016 PLOS ONE	2016	Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Mouse	Heart Skeletal muscle Nervous system Liver
Hagl 2016 Nutr Neurosci	2016	Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Jacobs 2016 J Physiol	2016	Jacobs RA, Lundby AM, Fenk S, Gehrig S, Siebenmann C, Flück D, Kirk N, Hilty MP, Lundby C (2016) Twenty-eight days of exposure to 3,454 m increases mitochondrial volume density in human skeletal muscle. J Physiol 594:1151-66.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Lund 2016 J Physiol	2016	Lund MT, Kristensen M, Hansen M, Tveskov L, Floyd AK, Støckel M, Vainer B, Poulsen SS, Helge JW, Prats C, Dela F (2016) Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes. J Physiol 594:4351-8.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Liver
Tam 2016 Eur J Appl Physiol	2016	Tam E, Bruseghini P, Calabria E, Sacco LD, Doria C, Grassi B, Pietrangelo T, Pogliaghi S, Reggiani C, Salvadego D, Schena F, Toniolo L, Verratti V, Vernillo G, Capelli C (2016) Gokyo Khumbu/Ama Dablam Trek 2012: effects of physical training and high-altitude exposure on oxidative metabolism, muscle composition, and metabolic cost of walking in women. Eur J Appl Physiol 116:129-44.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Human	Skeletal muscle
Shrum 2016 J Kidney	2016	Shrum S, MacMillan-Crow LA, Parajuli N (2016) Cold storage exacerbates renal and mitochondrial dysfunction following transplantation. J Kidney 2 pii: 114.	OXPHOS	N S CIV	Permeabilized tissue	Rat	Kidney
Bernardo 2015 J Nutr Biochem	2016	Bernardo AF, Cortez E, Neves FA, Vieira AKG, Soares V, Rodrigues-Cunha AC, Andrade DC, Thole AA, Gabriel-Costa D, Brum PC, Moura AS, Garcia-Souza EP (2015) Overnutrition during lactation leads to impairment in insulin signaling, upregulation of GLUT1 and increased mitochondrial carbohydrate oxidation in heart of weaned mice. J Nutr Biochem 29:124-32.	LEAK OXPHOS	F N NS	Permeabilized tissue	Mouse	Heart
Doerrier 2016 Mitochondrion	2016	Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Heart
Johnson 2016 Stem Cells Dev	2016	Johnson J, Lee W, Frazier AE, Vaghjiani V, Laskowski A, Rodriguez AL, Cagnone GL, McKenzie M, White SJ, Nisbet DR, Thorburn DR, St John JC (2016) Deletion of the complex I subunit NDUFS4 adversely modulates cellular differentiation. Stem Cells Dev 25:239-50.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Stem cells
Cacabelos 2016 Acta Neuropathol Commun	2016	Cacabelos D, Ramírez-Núñez O, Granado-Serrano AB, Torres P, Ayala V, Moiseeva V, Povedano M, Ferrer I, Pamplona R, Portero-Otin M, Boada J (2016) Early and gender-specific differences in spinal cord mitochondrial function and oxidative stress markers in a mouse model of ALS. Acta Neuropathol Commun 4:3.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized tissue Intact cells	Mouse	Nervous system Other cell lines
Yamada 2016 J Physiol	2016	Yamada T, Takakura H, Jue T, Hashimoto T, Ishizawa R, Furuichi Y, Kato Y, Iwanaka N, Masuda K (2016) Myoglobin and the regulation of mitochondrial respiratory chain complex IV. J Physiol 594:483-95.	LEAK OXPHOS	N S CIV Other combinations ROX		Mouse	Skeletal muscle Other cell lines
Volt 2016 J Pineal Res	2016	Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205.	OXPHOS ET	N NS	Permeabilized tissue	Mouse	Heart
Xiong 2016 Hypertension	2016	Xiong S, Wang P, Ma L, Gao P, Gong L, Li L, Li Q, Sun F, Zhou X, He H, Chen J, Yan Z, Liu D, Zhu Z (2016) Ameliorating endothelial mitochondrial dysfunction restores coronary function via transient receptor potential vanilloid 1-mediated protein kinase A/uncoupling protein 2 pathway. Hypertension 67:451-60.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Other cell lines
Johnson 2016 Diabetes	2016	Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Skeletal muscle
Krischek 2016 Mol Reprod Dev	2016	Krischek C, Janisch S, Naraballobh W, Brunner R, Wimmers K, Wicke M (2016) Altered incubation temperatures between embryonic Days 7 and 13 influence the weights and the mitochondrial respiratory and enzyme activities in breast and leg muscles of broiler embryos. Mol Reprod Dev 83:71-8.	LEAK OXPHOS	N S	Permeabilized tissue	Chicken	Skeletal muscle
Strifler 2016 PLOS ONE	2016	Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363.	LEAK OXPHOS	N S CIV NS ROX	Homogenate Isolated mitochondria	Rat	Liver
Pambianco 2016 Cell Rep	2016	Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23.	LEAK OXPHOS	F N S NS ROX	Permeabilized cells Isolated mitochondria Permeabilized tissue	Mouse	Skeletal muscle
Berressem 2016 PLOS ONE	2016	Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Gorbacheva 2016 International Symposium Mitochondrial Motility	2016	Gorbacheva OS, Strutynskyi RB, Khmil NV, Belosludtseva NV, Murzaeva SV, Korobeynikova MO, Alilova GA, Lezhnev EI, Mironova GD (2016) Study of the influence of flocalin on the energy and ion exchanges in rat liver mitochondria. International Symposium Mitochondrial Motility 73-7.	LEAK	F N S		Rat	Liver
Kancirova 2016 Physiol Res	2016	Kancirová I, Jašová M, Muráriková M, Sumbalová Z, Uličná O, Ravingerová T, Waczulíková I, Ziegelhöffer A, Ferko M (2016) Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium. Physiol Res 65:S611-19.	LEAK OXPHOS	F N	Isolated mitochondria	Rat	Heart
Grundmanova 2016 Physiol Res	2016	Grundmanová M, Jarkovská D, Süß A, Tůma Z, Marková M, Grundman Z, El-Kadi A, Čedíková M, Štengl M, Kuncová J (2016) Propofol-induced mitochondrial and contractile dysfunction of the rat ventricular myocardium. Physiol Res 65:S601-9.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Rat	Heart
Scott 2016 Thesis	2016	Scott KY (2016) Evaluation of cardiac mitochondrial function in the fructose-fed rat. Master's Thesis p98.	LEAK OXPHOS ET	F N S CIV ROX	Isolated mitochondria	Rat	Heart
Van Hoose 2016 J Nutr Biochem	2016	Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Heart
MacPherson 2016 Am J Physiol Cell Physiol	2016	MacPherson RE, Dragos SM, Ramos S, Sutton C, Frendo-Cumbo S, Castellani L, Watt MJ, Perry CG, Mutch DM, Wright DC (2016) Reduced ATGL-mediated lipolysis attenuates β-adrenergic-induced AMPK signaling, but not the induction of PKA-targeted genes, in adipocytes and adipose tissue. Am J Physiol Cell Physiol 311:C269-76.	OXPHOS LEAK	N	Permeabilized tissue	Mouse	Fat
Moll 2016 bioRxiv	2016	Moll CWI, Lindtner RA, Vogel GF, Brunner M, Gutleben K, Blauth M, Krumschnabel G, Ebner HL (2016) Bone marrow mesenchymal stem cells from osteoporotic patients do not show altered mitochondrial energetics or ultrastructure. bioRxiv doi.org/10.1101/046300.	LEAK ROUTINE OXPHOS ET	N S ROX	Intact cells Permeabilized cells	Human	Stem cells
Lark 2016 Am J Physiol Cell Physiol	2016	Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45.	LEAK OXPHOS ET	N Gp NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Roy 2016 Free Radic Biol Med	2016	Roy J, Fauconnier J, Oger C, Farah C, Angebault-Prouteau C, Thireau J, Bideaux P, Scheuermann V, Bultel-Poncé V, Demion M, Galano JM, Durand T, Lee JC, Le Guennec JY (2016) Non-enzymatic oxidized metabolite of DHA, 4(RS)-4-F_4t-neuroprostane protects the heart against reperfusion injury. Free Radic Biol Med 102:229-39.	OXPHOS ET	N S NS	Permeabilized cells	Rat	Heart
Valek 2016 Redox Biol	2016	Valek L, Häussler A, Dröse S, Eaton P, Schröder K, Tegeder I (2016) Redox-guided axonal regrowth requires cyclic GMP dependent protein kinase 1: Implication for neuropathic pain. Redox Biol 11:176-91.	OXPHOS LEAK	N S CIV ROX	Homogenate	Mouse	Nervous system
Casinelli 2016 Cell Death Discov	2016	Casinelli G, LaRosa J, Sharma M, Cherok E, Banerjee S, Branca M, Edmunds L, Wang Y, Sims-Lucas S, Churley L, Kelly S, Sun M, Stolz D, Graves JA (2016) N-Myc overexpression increases cisplatin resistance in neuroblastoma via deregulation of mitochondrial dynamics. Cell Death Discov 2:16082.	OXPHOS LEAK	N S	Permeabilized cells	Human	Nervous system Other cell lines
Shirey 2016 Biochemistry	2016	Shirey K, Stover KR, Cleary J, Hoang N, Hosler J (2016) Membrane-anchored cyclic peptides as effectors of mitochondrial oxidative phosphorylation. Biochemistry 55:2100-11.	LEAK OXPHOS ET	CIV NS N S	Isolated mitochondria SMP	Rat	Heart Liver
Witt 2016 Metab Brain Dis	2016	Witt AM, Larsen FS, Bjerring PN (2016) Accumulation of lactate in the rat brain during hyperammonaemia is not associated with impaired mitochondrial respiratory capacity. Metab Brain Dis 32:461-70.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Van Eunen 2016 BMC Biol	2016	van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM (2016) Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders. BMC Biol 14:107.	ET	F N	Isolated mitochondria	Mouse	Liver
Timpani 2016 Neurotherapeutics	2016	Timpani CA, Trewin AJ, Stojanovska V, Robinson A, Goodman CA, Nurgali K, Betik AC, Stepto N, Hayes A, McConell GK, Rybalka E (2016) Attempting to compensate for reduced neuronal nitric oxide synthase protein with nitrate supplementation cannot overcome metabolic dysfunction but rather has detrimental effects in Dystrophin-deficient mdx muscle. Neurotherapeutics 14:429-46.	LEAK OXPHOS ET	N CIV NS Other combinations ROX S	Permeabilized tissue	Mouse	Skeletal muscle
Briston 2016 Sci Rep	2016	Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Rat	Liver
Williams 2016 Diabetes	2016	Williams AS, Trefts E, Lantier L, Grueter C, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Integrin-linked kinase is necessary for the development of diet-induced hepatic insulin resistance. Diabetes 66:325-34.	OXPHOS LEAK	F N	Isolated mitochondria	Mouse	Liver
Klepinin 2016 J Bioenerg Biomembr	2016	Klepinin A, Ounpuu L, Guzun R, Chekulayev V, Timohhina N, Tepp K, Shevchuk I, Schlattner U, Kaambre T (2016) Simple oxygraphic analysis for the presence of adenylate kinase 1 and 2 in normal and tumor cells. J Bioenerg Biomembr 48:531-48.	OXPHOS	N NS	Permeabilized cells Permeabilized tissue Isolated mitochondria	Human Rat Mouse	Heart Nervous system Endothelial;epithelial;mesothelial cell Genital
Strifler 2016b PLOS ONE	2016	Strifler G, Tuboly E, Görbe A, Boros M, Pécz D, Hartmann P (2016) Targeting mitochondrial dysfunction with L-alpha glycerylphosphorylcholine. PLOS ONE 11:e0166682.	LEAK OXPHOS ET	N S NS Other combinations ROX	Homogenate	Rat	Liver
Torres 2016 Redox Biol	2016	Torres S, Matías N, Baulies A, Nuñez S, Alarcon-Vila C, Martinez L, Nuño N, Fernandez A, Caballeria J, Levade T, Gonzalez-Franquesa A, Garcia-Rovés P, Balboa E, Zanlungo S, Fabrías G, Casas J, Enrich C, Garcia-Ruiz C, Fernández-Checa JC (2016) Mitochondrial GSH replenishment as a potential therapeutic approach for Niemann Pick type C disease. Redox Biol 11:60-72.	LEAK ROUTINE OXPHOS ET	N S ROX	Homogenate Intact cells	Human Mouse	Nervous system Liver Endothelial;epithelial;mesothelial cell Fibroblast
Mickevicius 2016 Thesis	2016	Mickevicius L (2016) Effect of short time ischemia/reperfusion in vivo on rat kidney mitochondria oxidative phosphorylation. Diploma Thesis p38.	OXPHOS LEAK	N NS	Isolated mitochondria	Rat	Kidney
Chorner 2016 Am J Physiol Regul Integr Comp Physiol	2016	Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP (2016) Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates. Am J Physiol Regul Integr Comp Physiol 311:R1234-42.	LEAK OXPHOS	F N NS	Isolated mitochondria	Rat	Skeletal muscle
Frey 2016 Biochim Biophys Acta	2016	Frey S, Geffroy G, Desquiret-Dumas V, Gueguen N, Bris C, Belal S, Amati-Bonneau P, Chevrollier A, Barth M, Henrion D, Lenaers G, Bonneau D, Reynier P, Procaccio V (2016) The addition of ketone bodies alleviates mitochondrial dysfunction by restoring complex I assembly in a MELAS cellular model. Biochim Biophys Acta 1863:284-91.	ROUTINE LEAK ET	N S NS	Permeabilized cells Intact cells	Human	Nervous system
Galli 2016 Am J Physiol Regul Integr Comp Physiol	2016	Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72.	LEAK OXPHOS ET	N S CIV Other combinations ROX	Isolated mitochondria	Reptiles	Heart
Liang 2016 J Biol Chem	2016	Liang X, Liu L, Fu T, Zhou Q, Zhou D, Xiao L, Liu L, Kong Y, Xie H, Yi F, Lai L, Vega RB, Kelly DP, Smith SR, Gan Z (2016) Exercise inducible lactate dehydrogenase B regulates mitochondrial function in skeletal muscle. J Biol Chem 291:25306-18.	LEAK OXPHOS ET	N	Permeabilized tissue	Mouse	Skeletal muscle
Timmers 2016 Diabetes Care	2016	Timmers S, de Ligt M, Phielix E, van de Weijer T, Hansen J, Moonen-Kornips E, Schaart G, Kunz I, Hesselink MK, Schrauwen-Hinderling VB, Schrauwen P (2016) Resveratrol as add-on therapy in subjects with well-controlled type 2 diabetes: a randomized controlled trial. Diabetes Care 39:2211-17.	LEAK ET OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Ferguson 2016 J Bioenerg Biomembr	2016	Ferguson MA, Sutton RM, Karlsson M, Sjövall F, Becker LB, Berg RA, Margulies SS, Kilbaugh TJ (2016) Increased platelet mitochondrial respiration after cardiac arrest and resuscitation as a potential peripheral biosignature of cerebral bioenergetic dysfunction. J Bioenerg Biomembr 48:269-79.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Homogenate Intact cells	Pig	Nervous system Platelet
Maarman 2016 J Appl Physiol (1985)	2016	Maarman GJ, Andrew BM, Blackhurst DM, Ojuka EO (2016) Melatonin protects against uric acid-induced mitochondrial dysfunction, oxidative stress, and triglyceride accumulation in C₂C₁₂ myotubes. J Appl Physiol (1985) 122:1003-10.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Skeletal muscle
Alvarez-Mora 2016 Mol Neurobiol	2016	Alvarez-Mora MI, Rodriguez-Revenga L, Madrigal I, Guitart-Mampel M, Garrabou G, Milà M (2016) Impaired mitochondrial function and dynamics in the pathogenesis of FXTAS. Mol Neurobiol 54:6896-902.	ROUTINE	N S NS	Intact cells	Human	Fibroblast
Raesaenen 2016 Proc Natl Acad Sci U S A	2016	Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49.	LEAK OXPHOS ET	N S NS	Homogenate	Mouse	Heart
Koncsos 2016 Am J Physiol Heart Circ Physiol	2016	Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, Schlüter KD, Schreckenberg R, Radovits T, Oláh A, Mátyás C, Lux Á, Al-Khrasani M, Komlódi T, Bukosza N, Máthé D, Deres L, Barteková M, Rajtík T, Adameová A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P (2016) Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol 311:H927-43.	OXPHOS	N S NS	Isolated mitochondria	Rat	Heart
Chowdhury 2015 Biosci Rep	2016	Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286.	LEAK OXPHOS ET	N S NS ROX	Homogenate Isolated mitochondria	Mouse	Nervous system
Karlsson 2016 Mitochondrion	2016	Karlsson M, Ehinger JK, Piel S, Sjövall F, Henriksnäs J, Höglund U, Hansson MJ, Elmér E (2016) Changes in energy metabolism due to acute rotenone-induced mitochondrial complex I dysfunction – an in vivo large animal model. Mitochondrion 31:56-62.	ET	N ROX	Intact cells	Pig	Skeletal muscle Platelet
Speijer 2016 Biochem J	2016	Speijer D (2016) Being right on Q: shaping eukaryotic evolution. Biochem J 473:4103-27.		F N ROX
Perna 2016 Amino Acids	2016	Perna MK, Kokenge AN, Miles KN, Udobi KC, Clark JF, Pyne-Geithman GJ, Khuchua Z, Skelton MR (2016) Creatine transporter deficiency leads to increased whole body and cellular metabolism. Amino Acids 48:2057-65.	LEAK OXPHOS ET	N NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Salvadego 2016 J Appl Physiol (1985)	2016	Salvadego D, Keramidas ME, Brocca L, Domenis R, Mavelli I, Rittweger J, Eiken O, Mekjavic IB, Grassi B (2016) Separate and combined effects of a 10-d exposure to hypoxia and inactivity on oxidative function in vivo and mitochondrial respiration ex vivo in humans. J Appl Physiol (1985) 121:154-63.	LEAK OXPHOS ET	N ROX	Permeabilized tissue	Human	Skeletal muscle
Kucera 2016 Drug Chem Toxicol	2016	Kučera O, Endlicher R, Rychtrmoc D, Lotková H, Sobotka O, Červinková Z (2016) Acetaminophen toxicity in rat and mouse hepatocytes in vitro. Drug Chem Toxicol 40:448-56.	LEAK OXPHOS	N NS	Permeabilized cells	Mouse Rat	Liver
Spendiff 2016 J Physiol	2016	Spendiff S, Vuda M, Gouspillou G, Aare S, Perez A, Morais JA, Jagoe RT, Filion ME, Glicksman R, Kapchinsky S, MacMillan NJ, Pion CH, Aubertin-Leheudre M, Hettwer S, Correa JA, Taivassalo T, Hepple RT (2016) Denervation drives mitochondrial dysfunction in skeletal muscle of octogenarians. J Physiol 594:7361-79.	OXPHOS LEAK	N CIV NS ROX	Permeabilized tissue	Human Mouse	Skeletal muscle
Fisar 2016 Curr Alzheimer Res	2016	Fišar Z, Hroudová J, Hansíková H, Spáčilová J, Lelková P, Wenchich L, Jirák R, Zvěřová M, Zeman J, Martásek P, Raboch J (2016) Mitochondrial respiration in the platelets of patients with Alzheimer's disease. Curr Alzheimer Res 13:930-41.	LEAK OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Platelet
Fisar 2016b Folia Biol (Praha)	2016	Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66.	OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Pig	Nervous system
Fisar 2016a Folia Biol (Praha)	2016	Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Pig	Nervous system
Renner 2016 Mycotoxin Res	2016	Renner L, Kahlert S, Tesch T, Bannert E, Frahm J, Barta-Böszörményi A, Kluess J, Kersten S, Schönfeld P, Rothkötter HJ, Dänicke S (2016) Chronic DON exposure and acute LPS challenge: effects on porcine liver morphology and function. Mycotoxin Res 33:207-18.	LEAK OXPHOS	N	Isolated mitochondria	Pig	Liver
Schiffer 2016 Am J Physiol Cell Physiol	2016	Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61.	LEAK OXPHOS ET ROUTINE	N NS	Permeabilized cells Isolated mitochondria Intact cells	Human	Skeletal muscle HEK
Singh 2016 Mol Neurobiol	2016	Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904.	LEAK	N S ROX	Isolated mitochondria	Pig	Nervous system
Bombicino 2016 Arch Biochem Biophys	2016	Bombicino SS, Iglesias DE, Zaobornyj T, Boveris A, Valdez LB (2016) Mitochondrial nitric oxide production supported by reverse electron transfer. Arch Biochem Biophys 607:8-19.		N NS	Isolated mitochondria	Rat	Heart
Grimm 2016 Methods Mol Biol	2016	Grimm A, Schmitt K, Eckert A (2016) Advanced mitochondrial respiration assay for evaluation of mitochondrial dysfunction in Alzheimer's disease. Methods Mol Biol 1303:171-83.	LEAK OXPHOS ET	N CIV ROX	Isolated mitochondria	Mouse	Nervous system
Jardim-Messeder 2016 Anticancer Res	2016	Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41.	OXPHOS	CIV N S	Isolated mitochondria	Mouse	Liver Kidney
Eisenberg 2016 Nat Med	2016	Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 22:1428-38.	LEAK ET OXPHOS	N ROX	Isolated mitochondria	Mouse	Heart
Chakraborty 2016 Pancreatology	2016	Chakraborty M, Hickey AJ, Petrov MS, Macdonald JR, Thompson N, Newby L, Sim D, Windsor JA, Phillips AR (2016) Mitochondrial dysfunction in peripheral blood mononuclear cells in early experimental and clinical acute pancreatitis. Pancreatology 16:739-47.	LEAK OXPHOS ROUTINE ET	N Gp CIV NS ROX S	Permeabilized cells	Human Rat	Blood cells
Holzem 2016 FASEB J	2016	Holzem KM, Vinnakota KC, Ravikumar VK, Madden EJ, Ewald GA, Dikranian K, Beard DA, Efimov IR (2016) Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts. FASEB J 30:2698-707.	OXPHOS LEAK	F N	Permeabilized tissue Isolated mitochondria	Human	Heart
Larsen 2016 FASEB J	2016	Larsen FJ, Schiffer TA, Ørtenblad N, Zinner C, Morales-Alamo D, Willis SJ, Calbet JA, Holmberg HC, Boushel R (2016) High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation. FASEB J 30:417-27.	LEAK ROUTINE OXPHOS	N NS	Permeabilized cells Isolated mitochondria Intact cells	Human	Skeletal muscle
Van Schaardenburgh 2016 PLOS ONE	2016	van Schaardenburgh M, Wohlwend M, Rognmo Ø, Mattsson EJ (2016) Mitochondrial respiration after one session of calf raise exercise in patients with peripheral vascular disease and healthy older adults. PLOS ONE 11:e0165038.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human	Skeletal muscle
McCurdy 2016 JCI Insight	2016	McCurdy CE, Schenk S, Hetrick B, Houck J, Drew BG, Kaye S, Lashbrook M, Bergman BC, Takahashi DL, Dean TA, Nemkov T, Gertsman I, Hansen KC, Philp A, Hevener AL, Chicco AJ, Aagaard KM, Grove KL, Friedman JE (2016) Maternal obesity reduces oxidative capacity in fetal skeletal muscle of Japanese macaques. JCI Insight 1:e86612.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Other mammals	Skeletal muscle
Wang 2016 J Biol Chem	2016	Wang H, Lu J, Edmunds LR, Kulkarni S, Dolezal J, Tao J, Ranganathan S, Jackson L, Fromherz M, Stolz DB, Uppala R, Bharathi S, Monga SP, Goetzman ES, Prochownik EV (2016) Coordinated activities of multiple Myc-dependent and Myc-independent biosynthetic pathways in Hepatoblastoma. J Biol Chem 291:26241-51.	OXPHOS LEAK	N S NS	Homogenate	Mouse	Liver
Tretter 2016 Biochim Biophys Acta	2016	Tretter L, Patocs A, Chinopoulos C (2016) Succinate, an intermediate in metabolism, signal transduction, ROS, hypoxia, and tumorigenesis. https://doi.org/10.1016/j.bbabio.2016.03.012	LEAK OXPHOS	N S NS
Pravenec 2016 Physiol Genomics	2016	Pravenec M, Mlejnek P, Zídek V, Landa V, Šimáková M, Šilhavý J, Strnad H, Eigner S, Eigner Henke K, Škop V, Malínská H, Trnovská J, Kazdová L, Drahota Z, Mráček T, Houštěk J (2016) Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue. Physiol Genomics 48:420-7.	ET	F N	Isolated mitochondria	Rat	Fat
Chen 2016 Nat Chem Biol	2016	Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ (2016) Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol 12:937-43.	LEAK OXPHOS ET	N NS ROX	Isolated mitochondria	Human	HeLa
Hamilton 2016 Physiol Rep	2016	Hamilton DJ, Minze LJ, Kumar T, Cao TN, Lyon CJ, Geiger PC, Hsueh WA, Gupte AA (2016) Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice. Physiol Rep 4. pii: e12913.	LEAK OXPHOS	F N NS	Isolated mitochondria	Mouse	Heart
Melenovsky 2016 Eur J Heart Fail	2016	Melenovsky V, Petrak J, Mracek T, Benes J, Borlaug BA, Nuskova H, Pluhacek T, Spatenka J, Kovalcikova J, Drahota Z, Kautzner J, Pirk J, Houstek J (2016) Myocardial iron content and mitochondrial function in human heart failure: a direct tissue analysis. Eur J Heart Fail 19:522-30.		N S	Homogenate	Human	Heart
Bagur 2016 Biochim Biophys Acta	2016	Bagur R, Tanguy S, Foriel S, Grichine A, Sanchez C, Pernet-Gallay K, Kaambre T, Kuznetsov AV, Usson Y, Boucher F, Guzun R (2016) The impact of cardiac ischemia/reperfusion on the mitochondria-cytoskeleton interactions. Biochim Biophys Acta 1862:1159-71.	OXPHOS LEAK	N S	Permeabilized tissue	Rat	Heart
Pohland 2016 Neurochem Res	2016	Pohland M, Hagl S, Pellowska M, Wurglics M, Schubert-Zsilavecz M, Eckert GP (2016) MH84: a novel γ-secretase modulator/PPARγ agonist-improves mitochondrial dysfunction in a cellular model of Alzheimer's disease. Neurochem Res 41:231-42.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Kidney HEK
Reich 2016 Thesis	2016	Reich V (2016) Pathophysiologie und Verfahrensentwicklung: Mechanismen der Metabolisierung von Schwefelwasserstoff im mitochondrialen Atmungskreislauf von Lungenalveolarmakrophagen. Dissertation p91.	LEAK OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells	Mouse	Macrophage-derived
Asseburg 2016 Neuromolecular Med	2016	Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Smith 2016 Diabetes	2016	Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61.	LEAK OXPHOS ET	F N NS Other combinations ROX	Permeabilized cells Isolated mitochondria Permeabilized tissue	Mouse	Skeletal muscle Liver Fat
Zinner 2016 Front Physiol	2016	Zinner C, Morales-Alamo D, Ørtenblad N, Larsen FJ, Schiffer TA, Willis SJ, Gelabert-Rebato M, Perez-Valera M, Boushel R, Calbet JA, Holmberg HC (2016) The physiological mechanisms of performance enhancement with sprint interval training fiffer between the upper and lower extremities in humans. Front Physiol 7:426.	OXPHOS	N NS	Isolated mitochondria	Human	Skeletal muscle
Heim 2016 Thesis	2016	Heim A (2016) Tissue-specific seasonal changes in mitochondrial respiratory function and membrane composition in the golden-matled ground squirrel. Master's Thesis p77.	LEAK OXPHOS	F N NS Other combinations	Isolated mitochondria	Other mammals	Heart Skeletal muscle Liver Fat
Khattar 2016 J Neurosci Methods	2016	Khattar NK, Yablonska S, Baranov SV, Baranova OV, Kretz ES, Larkin TM, Carlisle DL, Richardson RM, Friedlander RM (2016) Isolation of functionally active and highly purified neuronal mitochondria from human cortex. J Neurosci Methods 263:1-6.	LEAK OXPHOS ET	N	Isolated mitochondria	Human Mouse	Nervous system
Villani 2016 Mol Metab	2016	Villani LA, Smith BK, Marcinko K, Ford RJ, Broadfield LA, Green AE, Houde VP, Muti P, Tsakiridis T, Steinberg GR (2016) The diabetes medication Canagliflozin reduces cancer cell proliferation by inhibiting mitochondrial complex-I supported respiration. Mol Metab 5:1048-56.	OXPHOS	N S ROX	Permeabilized cells	Human	Genital
Salin 2016 Physiol Biochem Zool	2016	Salin K, Auer SK, Rudolf AM, Anderson GJ, Selman C, Metcalfe NB (2016) Variation in metabolic rate among individuals is related to tissue-specific differences in mitochondrial LEAK respiration. Physiol Biochem Zool 89:511-23.	LEAK OXPHOS	N CIV NS ROX	Homogenate	Fishes	Skeletal muscle Liver
Du 2016 Thesis	2016	Du X (2016) Anthropogenic pollution effects on mitochondrial energy metabolism, gene expression, and genotypes of natural Fundulus heteroclitus populations. Dissertation p175.	LEAK OXPHOS ET	S CIV ROX N NS	Permeabilized cells	Fishes	Liver
Gariani 2016 J Hepatol	2016	Gariani K, Ryu D, Menzies KJ, Yi HS, Stein S, Zhang H, Perino A, Lemos V, Katsyuba E, Jha P, Vijgen S, Rubbia-Brandt L, Kim YK, Kim JT, Kim KS, Shong M, Schoonjans K, Auwerx J (2016) Inhibiting poly ADP-ribosylation increases fatty acid oxidation and protects against fatty liver disease. J Hepatol 66:132-41.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Liver
Tyrrell 2016 Redox Biol	2016	Tyrrell DJ, Bharadwaj MS, Jorgensen MJ, Register TC, Molina AJ (2016) Blood cell respirometry is associated with skeletal and cardiac muscle bioenergetics: Implications for a minimally invasive biomarker of mitochondrial health. Redox Biol 10:65-77. https://doi.org/10.1016/j.redox.2016.09.009	OXPHOS LEAK ET	N NS ROX	Permeabilized tissue Isolated mitochondria Intact cells	Other mammals Human	Skeletal muscle Blood cells Platelet
Mills 2016 Cell Metab	2016	Mills KF, Yoshida S, Stein LR, Uchida K, Yoshino J, Imai SI (2016) Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab 24:1–12.	OXPHOS LEAK ET	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Nissinen 2016 Sci Rep	2016	Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Skeletal muscle
Roempler 2016 J Biol Chem	2016	Römpler K, Müller T, Juris L, Wissel M, Vukotic M, Hofmann K, Deckers M (2016) Overlapping role of respiratory supercomplex factor Rcf2 and its N-terminal homolog Rcf3 in Saccharomyces cerevisiae. J Biol Chem 291:23769-78.	LEAK OXPHOS	N CIV NS ROX	Isolated mitochondria	Saccharomyces cerevisiae
Abdel-Rahman 2016 Oxid Med Cell Longev	2016	Abdel-Rahman EA, Mokhtar A, Aaliya A, Radwan Y, Yasseen B, Al-Okda A, Atwa A, Elhanafy E, Habashy M, Ali SS (2016) Resolving contributions of oxygen-consuming and ROS-generating enzymes at the synapse. Oxid Med Cell Longev p19.	LEAK OXPHOS	N NS ROX	Permeabilized cells	Mouse	Nervous system
Strifler 2016 Magyar Sebeszet	2016	Strifler G, Meszaros A, Pecz D, Ficzere A, Barath B, Mihaly B, Hartmann P (2016) A májfunkció vizsgálata respirometriával - Examination of liver mitochondria with respirometry. Magyar Sebészet 69:194–8.	OXPHOS LEAK	N S CIV NS ROX Other combinations	Homogenate	Rat	Liver
Salin 2016 Physiol Rep	2016	Salin K, Villasevil EM, Auer SK, Anderson GJ, Selman C, Metcalfe NB, Chinopoulos C (2016) Simultaneous measurement of mitochondrial respiration and ATP production in tissue homogenates and calculation of effective P/O ratios. Physiol Rep 10.14814/phy2.13007.	LEAK OXPHOS	N NS ROX	Homogenate	Fishes	Liver
Wolter 2016 J Thromb Haemost	2016	Wolter J, Schild L, Bock F, Hellwig A, Gadi I, Al-Dabet MM, Ranjan S, Rönicke R, Nawroth PP, Petersen KU, Mawrin C, Shahzad K, Isermann B (2016) Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system. J Thromb Haemost 14:2212-26.	OXPHOS	N S	Isolated mitochondria	Mouse	Nervous system
Hartmannova 2016 Hum Mol Genet	2016	Hartmannová H, Piherová L, Tauchmannová K, Kidd K, Acott PD, Crocker JF, Oussedik Y, Mallet M, Hodaňová K, Stránecký V, Přistoupilová A, Barešová V, Jedličková I, Živná M, Sovová J, Hůlková H, Robins V, Vrbacký M, Pecina P, Kaplanová V, Houštěk J, Mráček T, Thibeault Y, Bleyer AJ, Kmoch S (2016) Acadian variant of Fanconi syndrome is caused by mitochondrial respiratory chain complex I deficiency due to a non-coding mutation in complex I assembly factor NDUFAF6. Hum Mol Genet 25:4062-79.	LEAK OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human	Fibroblast
Dechandt 2016 Anal Biochem	2016	Dechandt CRP, Couto-Lima CA, Alberici LC (2016) Triglyceride depletion of brown adipose tissue enables analysis of mitochondrial respiratory function in permeabilized biopsies. Anal Biochem 515:55-60.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Rat	Fat
Mezera 2016 Oxid Med Cell Longev	2016	Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.	LEAK OXPHOS	N S	Permeabilized cells Isolated mitochondria	Rat	Liver
Scialo 2016 PLOS ONE	2016	Scialo F, Sriram A, Stefanatos R, Sanz A (2016) Practical recommendations for the use of the GeneSwitch Gal4 system to knock-Down genes in Drosophila melanogaster. PLOS ONE 11:e0161817.	LEAK OXPHOS	N CIV Other combinations ROX Gp	Homogenate	Drosophila
Amigo 2016 Aging Cell	2016	Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ (2016) Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity. Aging Cell 16:73-81.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Nervous system
Stier 2016 Methods Ecol Evol	2016	Stier A, Romestaing C, Schull Q, Lefol E, Robin JP, Roussel D, Bize P (2016) How to measure mitochondrial function in birds using red blood cells: a case study in the king penguin and perspectives in ecology and evolution. Methods Ecol Evol doi:10.1111/2041-210X.12724.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized tissue Intact cells	Birds	Skeletal muscle Blood cells
Brecht 2016 Toxicol In Vitro	2016	Brecht K, Riebel V, Couttet P, Paech F, Wolf A, Chibout SD, Pognan F, Krähenbühl S, Uteng M (2016) Mechanistic insights into selective killing of OXPHOS-dependent cancer cells by arctigenin. Toxicol In Vitro 40:55-65.	LEAK OXPHOS ET	N S CIV Other combinations ROX DQ	Permeabilized cells	Human	Islet cell;pancreas;thymus
Valenzuela 2016 Cell Death Dis	2016	Valenzuela R, Costa-Besada MA, Iglesias-Gonzalez J, Perez-Costas E, Villar-Cheda B, Garrido-Gil P, Melendez-Ferro M, Soto-Otero R, Lanciego JL, Henrion D, Franco R, Labandeira-Garcia JL (2016) Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration. Cell Death Dis 7:e2427.	OXPHOS ET	N	Isolated mitochondria	Mouse Rat	Nervous system
Talati 2016 Am J Respir Crit Care Med	2016	Talati MH, Brittain EL, Fessel JP, Penner N, Atkinson J, Funke M, Grueter C, Jerome WG, Freeman M, Newman JH, West J, Hemnes AR (2016) Mechanisms of lipid accumulation in the bone morphogenetic protein receptor type 2 mutant right ventricle. Am J Respir Crit Care Med 194:719-28.	LEAK	F N	Permeabilized tissue	Mouse	Heart
Szczepanowska 2016 EMBO J	2016	Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Heart
Duteil 2016 Cell Rep	2016	Duteil D, Tosic M, Lausecker F, Nenseth HZ, Müller JM, Urban S, Willmann D, Petroll K, Messaddeq N, Arrigoni L, Manke T, Kornfeld JW, Brüning JC, Zagoriy V, Meret M, Dengjel J, Kanouni T, Schüle R (2016) Lsd1 ablation triggers metabolic reprogramming of brown adipose tissue. Cell Rep 17:1008-21.	ET	F N S NS	Permeabilized tissue	Mouse	Fat
Loureiro 2016 Oxid Med Cell Longev	2016	Loureiro AC, do Rêgo-Monteiro IC, Louzada RA, Ortenzi VH, de Aguiar AP, de Abreu ES, Cavalcanti-de-Albuquerque JP, Hecht F, de Oliveira AC, Ceccatto VM, Fortunato RS, Carvalho DP (2016) Differential expression of NADPH oxidases depends on skeletal muscle fiber type in rats. Oxid Med Cell Longev 2016:6738701.	LEAK OXPHOS	N CIV NS ROX	Permeabilized tissue	Rat	Skeletal muscle
MiPNet17.03 Shredder vs Fibers	2015-06-18	Mitochondrial respiration in permeabilized fibers versus homogenate from fish liver and heart. An application study with the PBI-Shredder.	LEAK OXPHOS ET	N S NS	Homogenate	Fishes	Heart Liver
Boerma 2015 Radiat Res	2015	Boerma M, Singh P, Sridharan V, Tripathi P, Sharma S, Singh SP (2015) Effects of local heart irradiation in a glutathione S-transferase alpha 4-null mouse model. Radiat Res 183:610-9.	OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Heart
Hezel 2015 Redox Biol	2015	Hezel MP, Liu M, Schiffer TA, Larsen FJ, Checa A, Wheelock CE, Carlström M, Lundberg JO, Weitzberg E (2015) Effects of long-term dietary nitrate supplementation in mice. Redox Biol 5:234-42.	LEAK OXPHOS ET	N	Isolated mitochondria	Mouse	Skeletal muscle
Caito 2015 Antioxid Redox Signal	2015	Caito SW, Aschner M (2015) Mitochondrial redox dysfunction and environmental exposures. Antioxid Redox Signal 23:578-95.	OXPHOS	N S CIV	Isolated mitochondria	Human Mouse Rat Bovines Drosophila Fishes Hexapods	Heart Nervous system Liver Kidney Lung;gill Endothelial;epithelial;mesothelial cell
Yan 2015 BMC Cancer	2015	Yan B, Stantic M, Zobalova R, Bezawork-Geleta A, Stapelberg M, Stursa J, Prokopova K, Dong L, Neuzil J (2015) Mitochondrially targeted vitamin E succinate efficiently kills breast tumour-initiating cells in a complex II-dependent manner. BMC Cancer 15:401.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Human Mouse	Genital Other cell lines
Koliaki 2015 Cell Metab	2015	Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46.	LEAK OXPHOS ET	F N NS Other combinations ROX	Homogenate Isolated mitochondria	Human	Liver
Porter 2015 Shock	2015	Porter C, Herndon DN, Bhattarai N, Ogunbileje JO, Szczesny B, Szabo C, Toliver-Kinsky T, Sidossis LS (2015) Severe burn injury induces thermogenically functional mitochondria in murine white adipose tissue. Shock 44:258-64.	LEAK	F N S NS Other combinations	Permeabilized tissue	Mouse	Fat
Skemiene 2015 FEBS J	2015	Skemiene K, Liobikas J, Borutaite V (2015) Anthocyanins as substrates for mitochondrial complex I - protective effect against heart ischemic injury. FEBS J 282:963-71.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Heart
Lantier 2015 Diabetes	2015	Lantier L, Williams AS, Williams IM, Yang KK, Bracy DP, Goelzer M, James FD, Gius D, Wasserman DH (2015) SIRT3 is crucial for maintaining skeletal muscle insulin action and protects against severe insulin resistance in high fat fed mice. Diabetes 64:3081-92.	LEAK OXPHOS	F N	Permeabilized tissue	Mouse	Skeletal muscle
Acosta 2015 Obesity (Silver Spring)	2015	Acosta A, Camilleri M, Shin A, Vazquez-Roque MI, Iturrino J, Lanza IR, Nair KS, Burton D, O'Neill J, Eckert D, Carlson P, Vella A, Zinsmeister AR (2015) Association of UCP-3 rs1626521 with obesity and stomach functions in humans. Obesity (Silver Spring) 23:898-906.	LEAK OXPHOS	N S NS	Isolated mitochondria	Human	Skeletal muscle
Singh 2015 Free Radic Biol Med	2015	Singh P, Sharma R, McElhanon K, Allen CD, Megyesi JK, Beneš H, Singh SP (2015) Sulforaphane protects the heart from doxorubicin-induced toxicity. Free Radic Biol Med 86:90-101.	OXPHOS	N S CIV ROX	Permeabilized tissue	Mouse	Heart Other cell lines
Senyilmaz 2015 Nature	2015	Senyilmaz D, Virtue S, Xu X, Tan CY, Griffin JL, Miller AK, Vidal-Puig A, Teleman AA (2015) Regulation of mitochondrial morphology and function by stearoylation of TFR1. Nature 525:124-8.	OXPHOS ET	N S CIV NS	Permeabilized tissue	Drosophila
Zelenka 2015 Oxid Med Cell Longev	2015	Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.	LEAK ROUTINE ET	N S	Isolated mitochondria Intact cells	Rat	Liver Endothelial;epithelial;mesothelial cell Fibroblast
Konopka 2015 Diabetes	2015	Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H₂O₂ emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Human	Skeletal muscle
Mortensen 2015 Adv Exp Med Biol	2015	Mortensen OH, Jørgensen W, Frandsen L, Grunnet N, Quistorff B (2015) Effects of a high fat diet and taurine supplementation on metabolic parameters and skeletal muscle mitochondrial function in rats. Adv Exp Med Biol 803:387-95.	OXPHOS	N	Permeabilized tissue	Rat	Skeletal muscle
Johnson 2015 Aging Cell	2015	Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43.	LEAK OXPHOS	F N S NS ROX	Isolated mitochondria	Mouse	Skeletal muscle
Schwarzkopf 2015 Neuroscience	2015	Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Ramos-Filho 2015 PLoS One	2015	Ramos-Filho D, Chicaybam G, de-Souza-Ferreira E, Guerra Martinez C, Kurtenbach E, Casimiro-Lopes G, Galina A (2015) High intensity interval training (HIIT) induces specific changes in respiration and electron leakage in the mitochondria of different rat skeletal muscles. PLoS One 10:e0131766.	LEAK OXPHOS ET	F N S Gp NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Bonhoure 2015 Genes Dev	2015	Bonhoure N, Byrnes A, Moir RD, Hodroj W, Preitner F, Praz V, Marcelin G, Chua SC Jr, Martinez-Lopez N, Singh R, Moullan N, Auwerx J, Willemin G, Shah H, Hartil K, Vaitheesvaran B, Kurland I, Hernandez N, Willis IM1 (2015) Loss of the RNA polymerase III repressor MAF1 confers obesity resistance. Genes Dev 29:934-47.	OXPHOS	N S NS	Homogenate	Mouse	Liver
Li 2015 Sci Rep	2015	Li P, Wang B, Sun F, Li Y, Li Q, Lang H, Zhao Z, Gao P, Zhao Y, Shang Q, Liu D, Zhu Z (2015) Mitochondrial respiratory dysfunctions of blood mononuclear cells link with cardiac disturbance in patients with early-stage heart failure. Sci Rep 5:10229.	LEAK ROUTINE OXPHOS ET	N S NS	Intact cells	Human	Blood cells Lymphocyte
Youcef 2015 Biochem Pharmacol	2015	Youcef G, Belaidi E, Waeckel L, Fazal L, Clemessy M, Vincent MP, Zadigue G, Richer C, Alhenc-Gelas F, Ovize M, Pizard A (2015) Tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. Biochem Pharmacol 94:22-9.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart
Rovenko 2015 Comp Biochem Physiol A Mol Integr Physiol	2015	Rovenko BM, Kubrak OI, Gospodaryov DV, Yurkevych IS, Sanz A, Lushchak OV, Lushchak VI (2015) Restriction of glucose and fructose causes mild oxidative stress independently of mitochondrial activity and reactive oxygen species in Drosophila melanogaster. Comp Biochem Physiol A Mol Integr Physiol 187:27-39.	OXPHOS	N Gp CIV Other combinations ROX	Homogenate	Drosophila
Pasdar 2015 PLoS One	2015	Pasdar EA, Smits M, Stapelberg M, Bajzikova M, Stantic M, Goodwin J, Yan B, Stursa J, Kovarova J, Sachaphibulkij K, Bezawork-Geleta A, Sobol M, Filimonenko A, Tomasetti M, Zobalova R, Hozak P, Dong LF, Neuzil J (2015) Characterisation of mesothelioma-initiating cells and their susceptibility to anti-cancer agents. PLoS One 10:e0119549.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Schoettl 2015 Mol Metab	2015	Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42.	LEAK ROUTINE OXPHOS ET	F N S ROX	Isolated mitochondria Intact cells	Mouse	Fat Other cell lines
Haegler 2015 Toxicology	2015	Haegler P, Grünig D, Berger B, Krähenbühl S, Bouitbir J (2015) Impaired mitochondrial function in HepG2 cells treated with hydroxy-cobalamin[c-lactam]: A cell model for idiosyncratic toxicity. Toxicology 336:48-58.	OXPHOS	N S CIV NS		Human	Liver Other cell lines
Kilbaugh 2015 J Am Heart Assoc	2015	Kilbaugh TJ, Sutton RM, Karlsson M, Hansson MJ, Naim MY, Morgan RW, Bratinov G, Lampe JW, Nadkarni VM, Becker LB, Margulies SS, Berg RA (2015) Persistently altered brain mitochondrial bioenergetics after apparently successful resuscitation from cardiac arrest. J Am Heart Assoc 4(9) pii: e002232.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Pig	Nervous system
Li 2015 Oxid Med Cell Longev	2015	Li H, Miao W, Ma J, Xv Z, Bo H, Li J, Zhang Y and Ji LL (2015) Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome Activation with Mitophagy. Oxid Med Cell Longev: 357150.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Hagl 2015 Neurochem Int	2015	Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42.	LEAK OXPHOS ET	N S CIV	Isolated mitochondria	Mouse	Nervous system
Hagl 2015 Molecules	2015	Hagl S, Berressem D, Bruns B, Sus N, Frank J, Eckert GP (2015) Beneficial Effects of Ethanolic and Hexanic Rice Bran Extract on Mitochondrial Function in PC12 Cells and the Search for Bioactive Components. Molecules 20(9):16524-39.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Other cell lines
Errea 2015 J Neuroinflammation	2015	Errea O, Moreno B, Gonzalez-Franquesa A, Garcia-Roves PM, Villoslada P (2015) The disruption of mitochondrial axonal transport is an early event in neuroinflammation. J Neuroinflammation 12:152.	LEAK OXPHOS ET	N S CIV NS ROX	Homogenate	Mouse	Nervous system
Chweih 2015 Exp Physiol	2015	Chweih H, Castilho RF, Figueira TR (2015) Tissue and sex specificities in Ca(2+) handling by isolated mitochondria in conditions avoiding the permeability transition. Exp Physiol 100(9):1073-92.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart Skeletal muscle Nervous system Liver
Chekulayev 2015 Biochem Biophys Rep	2015	Chekulayev V, Mado K, Shevchuk I, Koit A, Kaldma A, Klepinin A, Timohhina N, Tepp K, Kandashvili M, Ounpuu L, Heck K, Truu L, Planken A, Valvere V, Kaambre T (2015) Metabolic remodeling in human colorectal cancer and surrounding tissues: alterations in regulation of mitochondrial respiration and metabolic fluxes. Biochem Biophys Rep 4:111-25.	OXPHOS	N S CIV ROX	Permeabilized tissue	Human	Endothelial;epithelial;mesothelial cell
Cahill 2015 J Biol Chem	2015	Cahill TJ, Leo V, Kelly M, Stockenhuber A, Kennedy NW, Bao L, Cereghetti G, Harper AR, Czibik G, Lao C, Bellahcene M, Steeples V, Ghaffari S, Yavari A, Mayer A, Poulton J, Ferguson D, Scorrano L, Hettiarachchi NT, Peers C, Boyle J, Hill RB, Simmons A, Watkins H, Dear TN, Ashrafian H (2015) Resistance of dynamin-related protein 1 oligomers to disassembly impairs mitophagy resulting in myocardial inflammation and heart failure. J Biol Chem 290:25907-19.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Heart
Cappel 2015 PLoS One	2015	Cappel DA, Lantier L, Palmisano BT, Wasserman DH, Stafford JM (2015) CETP expression protects female mice from obesity-induced decline in exercise capacity. PLoS One 10:e0136915.	OXPHOS	F N	Permeabilized tissue	Mouse	Skeletal muscle
Imran 2015 J Neurochem	2015	Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Rat	Nervous system
Sidossis 2015 Cell Metab	2015	Sidossis LS, Porter C, Saraf MK, Børsheim E, Radhakrishnan RS, Chao T, Ali A, Chondronikola M, Mlcak R, Finnerty CC, Hawkins HK, Toliver-Kinsky T, Herndon DN (2015) Browning of subcutaneous white adipose tissue in humans after severe adrenergic stress. Cell Metab 22:219-27.	LEAK	F N NS Other combinations	Permeabilized cells	Human Mouse	Fat
Houben 2015 Mitochondrion	2015	Houben R, Leleu C, Fraipont A, Serteyn D, Votion DM (2015) Determination of muscle mitochondrial respiratory capacity in Standardbred racehorses as an aid to predicting exertional rhabdomyolysis. Mitochondrion 24:99-104.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Karadayian 2015 Neuroscience	2015	Karadayian AG, Bustamante J, Czerniczyniec A, Lombardi P, Cutrera RA, Lores-Arnaiz S (2015) Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum. Neuroscience 304:47-59.	LEAK OXPHOS	N S Other combinations	Isolated mitochondria	Mouse	Nervous system
Larsen 2015 Physiol Rep	2015	Larsen S, Scheede-Bergdahl C, Whitesell T, Boushel R, Bergdahl A (2015) Increased intrinsic mitochondrial respiratory capacity in skeletal muscle from rats with streptozotocin-induced hyperglycemia. Physiol Rep 3 pii:e12467.	LEAK OXPHOS	F N CIV NS Other combinations ROX	Permeabilized tissue	Rat	Skeletal muscle
Leman 2015 Int J Biochem Cell Biol	2015	Leman G, Gueguen N, Desquiret-Dumas V, Kane MS, Wettervald C, Chupin S, Chevrollier A, Lebre AS, Bonnefont JP, Barth M, Amati-Bonneau P, Verny C, Henrion D, Bonneau D, Reynier P, Procaccio V (2015) Assembly defects induce oxidative stress in inherited mitochondrial complex I deficiency. Int J Biochem Cell Biol 65:91-103.		N S CIV	Permeabilized cells	Human	Endothelial;epithelial;mesothelial cell Fibroblast
Ortiz 2015 J Pineal Res	2015	Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.	LEAK OXPHOS ET	N S	Homogenate Isolated mitochondria
Hanssen 2015 Nat Med	2015	Hanssen MJ, Hoeks J, Brans B, van der Lans AA, Schaart G, van den Driessche JJ, Jörgensen JA, Boekschoten MV, Hesselink MK, Havekes B, Kersten S, Mottaghy FM, van Marken Lichtenbelt WD, Schrauwen P (2015) Short-term cold acclimation improves insulin sensitivity in patients with type 2 diabetes mellitus. Nat Med 21:863-5.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Sundstroem 2015 PhD Thesis	2015	Sundstrøm T (2015) Experimental modeling and novel therapeutic strategies in melanoma brain metastasis. PhD Thesis 1-146.	ET	N S NS ROX		Mouse	Nervous system
Correa 2015 Critical Care Horizon	2015	Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 .	LEAK OXPHOS	N S CIV ROX	Isolated mitochondria	Pig	Liver
Dueregger 2015 PLoS One	2015	Dueregger A, Schöpf B, Eder T, Höfer J, Gnaiger E, Aufinger A, Kenner L, Perktold B, Ramoner R, Klocker H, Eder IE (2015) Differential utilization of dietary fatty acids in benign and malignant cells of the prostate. PLoS One 10(8):e0135704.	LEAK ROUTINE OXPHOS ET	F N NS ROX	Permeabilized cells Permeabilized tissue	Human	Genital Other cell lines
Grevengoed 2015 J Lipid Res	2015	Grevengoed TJ, Martin SA, Katunga L, Cooper DE, Anderson EJ, Murphy RC, Coleman RA (2015) Acyl-CoA synthetase 1 deficiency alters cardiolipin species and impairs mitochondrial function. J Lipid Res 56:1572-82.	LEAK OXPHOS	F N NS ROX	Permeabilized tissue	Mouse	Heart Other cell lines HEK
George 2015 BA Thesis	2015	George M (2015) Assessing mitochondrial lactate oxidation in male rat permeabilized skeletal muscle fibers highlights important experimental considerations. BA Thesis 1-32.	OXPHOS	N	Permeabilized tissue	Rat	Skeletal muscle
Khera 2015 Placenta	2015	Khera A, Dong LF, Holland OJ, Vanderlelie J, Pasdar EA, Neuzil J, Perkins AV (2015) Selenium supplementation induces mitochondrial biogenesis in trophoblasts. Placenta 36:863-9.	LEAK ROUTINE OXPHOS ET	N S CIV	Permeabilized cells Intact cells	Human	Genital Other cell lines
Harrison 2015 J Appl Physiol	2015	Harrison DK, Fasching M, Fontana-Ayoub M, Gnaiger E (2015) Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. J Appl Physiol 119:1210-8. https://doi.org/10.1152/japplphysiol.00146.2015	OXPHOS	N	Isolated mitochondria	Mouse Bovines	Heart
Kilbaugh 2015 PLoS One	2015	Kilbaugh TJ, Lvova M, Karlsson M, Zhang Z, Leipzig J, Wallace DC, Margulies SS (2015) Peripheral blood mitochondrial DNA as a biomarker of cerebral mitochondrial dysfunction following traumatic brain injury in a porcine model. PLoS One 10:e0130927.	LEAK OXPHOS	N S NS	Homogenate	Pig	Nervous system
Kilbaugh 2015 Exp Neurol	2015	Kilbaugh TJ, Karlsson M, Byro M, Bebee A, Ralston J, Sullivan S, Duhaime AC, Hansson MJ, Elmér E, Margulies SS (2015) Mitochondrial bioenergetic alterations after focal traumatic brain injury in the immature brain. Exp Neurol 271:136-144.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized tissue Homogenate	Pig	Nervous system
Du 2015 Aquat Toxicol	2015	Du X, Crawford DL, Oleksiak MF (2015) Effects of anthropogenic pollution on the oxidative phosphorylation pathway of hepatocytes from natural populations of Fundulus heteroclitus. Aquat Toxicol 165:231-40.	LEAK OXPHOS ET	N S CIV ROX	Permeabilized cells	Fishes	Liver
Gainutdinov 2015 Arch Biochem Biophys	2015	Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6.	LEAK OXPHOS	N S ROX	Isolated mitochondria	Mouse	Nervous system
Kelly 2015 Biotechnol J	2015	Kelly PS, Breen L, Gallagher C, Kelly S, Henry M, Lao NT, Meleady P, O'Gorman D, Clynes M, Barron N (2015) Re-programming CHO cell metabolism using miR-23 tips the balance towards a highly productive phenotype. Biotechnol J 10:1029-40.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Intact cells Permeabilized cells		CHO
McCommis 2015 Cell Metab	2015	McCommis KS, Chen Z, Fu X, McDonald WG, Colca JR, Kletzien RF, Burgess SC, Finck BN (2015) Loss of mitochondrial pyruvate carrier 2 in the liver leads to defects in gluconeogenesis and compensation via pyruvate-alanine cycling. Cell Metab 22:682-94.	OXPHOS	N S	Permeabilized cells Isolated mitochondria	Mouse	Liver
Wessels 2015 Diabetes Obes Metab	2015	Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60.	LEAK OXPHOS ET	F N S	Isolated mitochondria	Rat	Skeletal muscle
Kruska 2015 Biochim Biophys Acta	2015	Kruska N, Schönfeld P, Pujol A, Reiser G (2015) Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions. Biochim Biophys Acta 1852:925-36.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Nervous system
Nordquist 2015 J Am Soc Nephrol	2015	Nordquist L, Friederich-Persson M, Fasching A, Liss P, Shoji K, Nangaku M, Hansell P, Palm F (2015) Activation of hypoxia-inducible factors prevents diabetic nephropathy. J Am Soc Nephrol 26:328-38.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Kidney
Ziak 2015 Mitochondrion	2015	Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.	LEAK OXPHOS ET	N S NS ROX	Homogenate Isolated mitochondria	Human	Skeletal muscle
Papazova 2015 Am J Physiol Renal Physiol	2015	Papazova DA, Friederich-Persson M, Joles JA, Verhaar MC (2015) Renal transplantation induces mitochondrial uncoupling, increased kidney oxygen consumption, and decreased kidney oxygen tension. Am J Physiol Renal Physiol 308:F22-8.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Kidney
Christiansen 2015 J Vet Med Sci	2015	Christiansen LB, Dela F, Koch J, Yokota T (2015) Tissue-specific and substrate-specific mitochondrial bioenergetics in feline cardiac and skeletal muscles. J Vet Med Sci 77:669-75.	LEAK OXPHOS ET	F N S CIV NS Other combinations ROX	Permeabilized tissue	Cat	Heart Skeletal muscle
Iftikar 2015 Comp Biochem Physiol A Mol Integr Physiol	2015	Iftikar FI, Morash AJ, Cook DG, Herbert NA, Hickey AJ (2015) Temperature acclimation of mitochondria function from the hearts of a temperate wrasse (Notolabrus celidotus). Comp Biochem Physiol A Mol Integr Physiol 184:46-55.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Fishes	Heart
Mourier 2015 J Cell Biol	2015	Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42.	LEAK OXPHOS ET	N S Gp Other combinations	Permeabilized cells Isolated mitochondria	Mouse	Heart Fibroblast
Guzun 2015 Acta Physiol (Oxf)	2015	Guzun R, Kaambre T, Bagur R, Grichine A, Usson Y, Varikmaa M, Anmann T, Tepp K, Timohhina N, Shevchuk I, Chekulayev V, Boucher F, Dos Santos P, Schlattner U, Wallimann T, Kuznetsov AV, Dzeja P, Aliev M, Saks V (2015) Modular organization of cardiac energy metabolism:energy conversion, transfer and feedback regulation. Acta Physiol (Oxf) 213:84-106.	OXPHOS	N	Permeabilized cells Isolated mitochondria	Rat	Heart
Wuest 2015 J Physiol	2015	Wüst RC, Helmes M, Stienen GJ (2015) Rapid changes in NADH and flavin autofluorescence in rat cardiac trabeculae reveal large mitochondrial complex II reserve capacity. J Physiol 593:1829-40.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Rat	Heart
Dahl 2015 Acta Physiol (Oxf)	2015	Dahl R, Larsen S, Dohlmann TL, Qvortrup K, Helge JW, Dela F, Prats C (2015) Three dimensional reconstruction of the human skeletal muscle mitochondrial network as a tool to assess mitochondrial content and structural organization. Acta Physiol (Oxf) 213:145-55.	LEAK OXPHOS ET	N CIV NS	Permeabilized tissue	Human	Skeletal muscle
Hasli 2015 Master Thesis	2015	Hasli PR (2015) Characterization of mitochondrial respiration and quality differences in diploid and triploid Atlantic salmon (Salmo salar L.) at 5 °C, 10 °C and 15 °C. Master Thesis:1-147.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Fishes	Heart Skeletal muscle
Cell ergometry	2015	Gnaiger E (2015) Cell ergometry and OXPHOS. Mitochondr Physiol Network 2015-01-18.	LEAK OXPHOS ET	N S NS ROX
Krumschnabel 2015 Methods Mol Biol	2015	Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Nervous system
Hendricks 2015 Thesis	2015	Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse	Nervous system
Hagl 2015 J Alzheimers Dis	2015	Hagl S, Grewal R, Ciobanu I, Helal A, Khayyal MT, Muller WE, Eckert GP (2015) Rice bran extract compensates mitochondrial dysfunction in a cellular model of early Alzheimer’s disease. J Alzheimers Dis 43:927-38.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Rat	Nervous system Kidney Other cell lines
Lark 2015 Front Physiol	2015	Lark DS, Reese LR, Ryan TE, Torres MJ, Smith CD, Lin CT, Neufer PD (2015) Protein kinase A governs oxidative phosphorylation kinetics and oxidant emitting potential at complex I. https://doi.org/10.3389/fphys.2015.00332	LEAK ET OXPHOS	N S	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle Liver
Bowen 2015 Eur J Heart Fail	2015	Bowen TS, Rolim NP, Fischer T, Baekkerud FH, Medeiros A, Werner S, Brønstad E, Rognmo O, Mangner N, Linke A, Schuler G, Silva GJ, Wisløff U, Adams V (2015) Heart failure with preserved ejection fraction induces molecular, mitochondrial, histological, and functional alterations in rat respiratory and limb skeletal muscle. Eur J Heart Fail 17:263-72.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Rat	Skeletal muscle
Vincent 2015 Front Physiol	2015	Vincent G, Lamon S, Gant N, Vincent PJ, MacDonald JR, Markworth JF, Edge JA, Hickey AJ (2015) Changes in mitochondrial function and mitochondria associated protein expression in response to 2-weeks of high intensity interval training. Front Physiol 6:51.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Skeletal muscle
Abou-Hamdan 2015 Methods Enzymol	2015	Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28.	OXPHOS	N S CIV	Intact cells Homogenate Isolated mitochondria	Human Pig Mouse Rat	Heart Nervous system Liver Kidney Genital CHO Neuroblastoma Fibroblast
Ping 2015 Oxid Med Cell Longev	2015	Ping Z, Zhang LF, Cui YJ, Chang YM, Jiang CW, Meng ZZ, Xu P, Liu HY, Wang DY, Cao XB (2015) The protective effects of Salidroside from exhaustive exercise-induced heart injury by enhancing the PGC-1𝛼–NRF1/NRF2 pathway and mitochondrial respiratory function in rats. Oxid Med Cell Longev Article ID 876825.	OXPHOS ET	N S CIV ROX	Permeabilized tissue	Rat	Heart
Aroor 2015 Diabetes	2015	Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.	LEAK ROUTINE OXPHOS ET	F N S NS	Isolated mitochondria	Mouse	Liver
Laursen 2015 Proc Natl Acad Sci USA	2015	Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO (2015) Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proc Natl Acad Sci USA 112:1607-12.	LEAK OXPHOS	N	Isolated mitochondria	Other mammals	Nervous system HEK
Kluckova 2015 Methods Mol Biol	2015	Kluckova K, Dong L, Bajzikova M, Rohlena J, Neuzil J (2015) Evaluation of respiration of mitochondria in cancer cells exposed to mitochondria-targeted agents. Methods Mol Biol 1265:181-94.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Irving 2015 J Clin Endocrinol Metab	2015	Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS (2015) Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab 100:1654-63.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Human	Skeletal muscle
Williams 2015 J Biol Chem	2015	Williams AS, Kang L, Zheng J, Grueter CA, Bracy DP, James FD, Pozzi A, Wasserman DH (2015) Integrin α1-null mice exhibit improved fatty liver when fed a high fat diet despite severe hepatic insulin resistance. J Biol Chem 290:6546-57.	LEAK OXPHOS	F N	Permeabilized tissue	Mouse	Liver Other cell lines
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol	2015	Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Rat	Liver
Schoettl 2015 Endocrinology	2015	Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33.	LEAK ROUTINE OXPHOS ET	N S ROX	Permeabilized cells Isolated mitochondria Intact cells	Mouse	Fat
Jeger 2015 BioMed Res Internat	2015	Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human	Skeletal muscle Liver Other cell lines
Porter 2015 Med Sci Sports Exerc	2015	Porter C, Reidy PT, Bhattarai N, Sidossis LS, Rasmussen BB (2015) Resistance exercise training alters mitochondrial function in human skeletal muscle. Med Sci Sports Exerc 47:1922-31.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Human	Skeletal muscle
Tan 2015 Cell Metab	2015	Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse	Endothelial;epithelial;mesothelial cell Genital Other cell lines
Lemoine 2015 Transplantation	2015	Lemoine S, Pillot B, Rognant N, Augeul L, Rayberin M, Varennes A, Laville M, Ovize M, Juillard L (2015) Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition. Transplantation. 99:717-23	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Kidney
Wahrheit 2015 Eng Life Sci	2015	Wahrheit J, Nonnenmacher Y, Sperber S, Heinzle E (2015) High-throughput respiration screening of single mitochondrial substrates using permeabilized CHO cells highlights control of mitochondria metabolism. Eng Life Sci 15:184-94.	LEAK OXPHOS	N S ROX	Permeabilized cells	Other mammals	Genital
Cannavino 2015 J Physiol	2015	Cannavino J, Brocca L, Sandri M, Grassi B, Bottinelli R, Pellegrino MA (2015) The role of alterations in mitochondrial dynamics and PGC-1α over-expression in fast muscle atrophy following hindlimb unloading. J Physiol 593:1981-95.	OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Tapia 2015 Crit Care	2015	Tapia P, Soto D, Bruhn A, Alegría L, Jarufe N, Luengo C, Kattan E, Regueira T, Meissner A, Menchaca R, Vives MI, Echeverría N, Ospina-Tascón G, Bakker J, Hernández G (2015) Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion. Crit Care 19:188.	LEAK OXPHOS	N NS	Isolated mitochondria	Other mammals	Liver
Ehinger 2015 J Neurol	2015	Ehinger JK, Morota S, Hansson MJ, Paul G, Elmér E (2015) Mitochondrial dysfunction in blood cells from amyotrophic lateral sclerosis patients. J Neurol 262:1493-503.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells Lymphocyte Platelet
Hansson 2015 Eur J Pharmacol	2015	Hansson MJ, Llwyd O, Morin D, de Paulis D, Arnoux T, Gouarné C, Koul S, Engblom H, Bordet T, Tissier R, Arheden H, Erlinge D, Halestrap AP, Berdeaux A, Pruss RM, Schaller S (2015) Differences in the profile of protection afforded by TRO40303 and mild hypothermia in models of cardiac ischemia/reperfusion injury. Eur J Pharmacol 760:7-19.	LEAK OXPHOS ET	N S NS	Permeabilized tissue	Pig	Heart
Chu 2015 Liver Transpl	2015	Chu MJ, Hickey AJ, Jiang Y, Petzer A, Bartlett AS, Phillips AR (2015) Mitochondrial dysfunction in steatotic rat livers occurs because a defect in complex I makes the liver susceptible to prolonged cold ischemia. Liver Transpl 21:396-407.	LEAK OXPHOS ET	N S ROX	Homogenate	Rat	Liver
Kake-Guena 2015 J Exp Zool A Ecol Genet Physiol	2015	Kake-Guena SA, Touisse K, Vergilino R, Dufresne F, Blier PU, Lemieux H1 (2015) Assessment of mitochondrial functions in Daphnia pulex clones using high-resolution respirometry. J Exp Zool A Ecol Genet Physiol 323:292-300.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Crustaceans
Bonsignore 2015 Mech Ageing Dev	2015	Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Ludzki 2015 Diabetes	2015	Ludzki A, Paglialunga S, Smith BK, Herbst EA, Allison MK, Heigenhauser GJ, Neufer PD, Holloway GP (2015) Rapid repression of ADP transport by palmitoyl-CoA is attenuated by exercise training in humans; a potential mechanism to decrease oxidative stress and improve skeletal muscle insulin signaling. Diabetes 64:2769-79.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human Mouse	Skeletal muscle
Drechsler 2015 Intensive Care Medicine Experimental	2015	Drechsler S, Weixelbaumer KM, Weidinger A, Raeven P, Khadem A, Redl H, van Griensven M, Bahrami S, Remick D, Kozlov A, Osuchowski MF (2015) Why do they die? Comparison of selected aspects of organ injury and dysfunction in mice surviving and dying in acute abdominal sepsis. Intensive Care Medicine Experimental 3:12.	LEAK OXPHOS ET	N S	Homogenate	Mouse	Liver Kidney
Nelson 2015 Master Thesis	2015	Nelson MB (2015) The role of receptors for advanced glycation end-products (RAGE) and ceramide in cardiovascular disease. Master Thesis 1-53.	LEAK OXPHOS ET	N S NS	Permeabilized cells Permeabilized tissue	Mouse Rat	Heart Other cell lines
Makrecka-Kuka 2015 Biomolecules	2015	Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. https://doi.org/10.3390/biom5031319	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Homogenate Isolated mitochondria Intact cells	Human Mouse	Heart Nervous system HEK
Grabez 2015 J Anim Sci	2015	Grabež V, Kathri M, Phung V, Moe KM, Slinde E, Skaugen M, Saarem K, Egelandsdal B (2015) Protein expression and oxygen consumption rate of early postmortem mitochondria relate to meat tenderness. J Anim Sci 93:1967-79.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Permeabilized tissue	Bovines	Skeletal muscle
Richman 2015 PLoS Genet	2015	Richman TR, Ermer JA, Davies SM, Perks KL, Viola HM, Shearwood AM, Hool LC, Rackham O, Filipovska A (2015) Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet 11:e1005089.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Mouse	Heart Liver
Hagve 2015 Am J Physiol Endocrinol Metab	2015	Hagve M, Gjessing PF, Fuskevåg OM, Larsen TS, Irtun Ø (2015) Skeletal muscle mitochondria exhibit decreased pyruvate oxidation capacity and increased ROS emission during surgery-induced acute insulin resistance. Am J Physiol Endocrinol Metab 308:E613-20.	LEAK OXPHOS	F N	Isolated mitochondria	Pig	Skeletal muscle Liver
Herbst 2015 J Physiol	2015	Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801.	LEAK OXPHOS	N S NS	Permeabilized tissue Isolated mitochondria	Mouse	Nervous system
Schrauwen-Hinderling 2015 Antioxid Redox Signal	2015	Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51.	LEAK OXPHOS	F N S CIV	Permeabilized tissue Isolated mitochondria	Human	Heart Skeletal muscle
Soares 2015 PLoS One	2015	Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600.	LEAK OXPHOS ET	N S Gp NS Other combinations ROX	Permeabilized tissue Isolated mitochondria	Hexapods	Skeletal muscle
Lim 2015 Am J Cancer Res	2015	Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701.	LEAK ROUTINE OXPHOS	N S	Permeabilized cells Isolated mitochondria Intact cells	Human	Kidney Other cell lines HEK HeLa Fibroblast
Christiansen 2015 Am J Physiol Heart Circ Physiol	2015	Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue Isolated mitochondria	Cat	Heart Skeletal muscle
Melo Hanchuk 2015 Cell Signal	2015	Melo Hanchuk TD, Papa PF, La Guardia PG, Vercesi AE, Kobarg J (2015) Nek5 interacts with mitochondrial proteins and interferes negatively in mitochondrial mediated cell death and respiration. Cell Signal 27:1168-77.	LEAK OXPHOS	N S CIV ROX	Permeabilized cells	Human	HEK
Paglialunga 2015 Diabetologia	2015	Paglialunga S, Ludzki A, Root-McCaig J, Holloway GP (2015) In adipose tissue, increased mitochondrial emission of reactive oxygen species is important for short-term high-fat diet-induced insulin resistance in mice. Diabetologia 58:1071-80.	LEAK OXPHOS	F N	Permeabilized tissue	Mouse	Fat
Flatters 2015 Prog Mol Biol Transl Sci	2015	Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.	OXPHOS ET	N S CIV NS	Homogenate Isolated mitochondria	Rat	Nervous system
Beier 2015 FASEB J	2015	Beier UH, Angelin A, Akimova T, Wang L, Liu Y, Xiao H, Koike MA, Hancock SA, Bhatti TR, Han R, Jiao J, Veasey SC, Sims CA, Baur JA, Wallace DC, Hancock WW (2015) Essential role of mitochondrial energy metabolism in Foxp3⁺ T-regulatory cell function and allograft survival. FASEB J 29:2315-26. https://doi.org/10.1096/fj.14-268409	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Singh 2015 Biochim Biophys Acta	2015	Singh F, Charles AL, Schlagowski AI, Bouitbir J, Bonifacio A, Piquard F, Krähenbühl S, Geny B, Zoll J (2015) Reductive stress impairs myoblasts mitochondrial function and triggers mitochondrial hormesis. Biochim Biophys Acta 1853:1574-85.	LEAK OXPHOS	N S NS	Permeabilized tissue	Mouse	Skeletal muscle
Joergensen 2015 J Cereb Blood Flow Metab	2015	Jørgensen T, Grunnet N, Quistorff B (2015) One-year high fat diet affects muscle-but not brain mitochondria. J Cereb Blood Flow Metab 35:943-50.	LEAK OXPHOS	F N S Other combinations	Isolated mitochondria	Rat	Skeletal muscle Nervous system
Wang 2015 Nat Commun	2015	Wang Y, Oxer D, Hekimi S (2015) Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis. Nat Commun 6:6393.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Heart Skeletal muscle Kidney
Chausse 2015 PLoS One	2015	Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ (2015) Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413.	LEAK OXPHOS	N S CIV	Isolated mitochondria	Rat	Heart Skeletal muscle Nervous system Liver
Czerniczyniec 2015 Brain Res	2015	Czerniczyniec A, La Padula P, Bustamante J, Karadayian AG, Lores-Arnaiz S, Costa LE (2015) Mitochondrial function in rat cerebral cortex and hippocampus after short- and long-term hypobaric hypoxia. Brain Res 1598:66-75.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Nervous system
Rodrigues 2016 Biochem J	2015	Rodrigues MF, Obre E, Melo FH, Santos-Jr GC, Galina A, Jasiulionis MG, Rossignol R, Rumjanek FD, Amoedo ND (2016) Enhanced OXPHOS, glutaminolysis and beta-oxidation constitute the metastatic phenotype of melanoma cells. https://doi.org/10.1042/BJ20150645	LEAK ROUTINE OXPHOS ET	F N S ROX	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Jiroutkova 2015 Crit Care	2015	Jiroutková K, Krajčová A, Ziak J, Fric M, Waldauf P, Džupa V, Gojda J, Němcova-Fürstová V, Kovář J, Elkalaf M, Trnka J, Duška F (2015) Mitochondrial function in skeletal muscle of patients with protracted critical illness and ICU-acquired weakness. Crit Care 19:448.	LEAK OXPHOS ET	N S Gp CIV NS Other combinations ROX	Homogenate	Human	Skeletal muscle
Hanssen 2015 Diabetes	2015	Hanssen MJ, van der Lans AA, Brans B, Hoeks J, Jardon KM, Schaart G, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Short-term cold acclimation recruits brown adipose tissue in obese humans. Diabetes 65:1179-89.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Baraldi 2015 J Nutr Biochem	2015	Baraldi FG, Vicentini TM, Teodoro BG, Dalalio FM, Dechandt CR, Prado IM, Curti C, Cardoso FC, Uyemura SA, Alberici LC (2015) The combination of conjugated linoleic acid (CLA) and extra virgin olive oil increases mitochondrial and body metabolism and prevents CLA-associated insulin resistance and liver hypertrophy in C57Bl/6 mice. J Nutr Biochem 28:147-54.	OXPHOS LEAK	N	Isolated mitochondria	Mouse	Liver
Janssens 2015 Nutr Metab (Lond)	2015	Janssens S, Heemskerk MM, van den Berg SA, van Riel NA, Nicolay K, Willems van Dijk K, Prompers JJ (2015) Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance. Nutr Metab (Lond) 12:57.	LEAK OXPHOS	F N	Isolated mitochondria	Rat	Liver
Hansen 2015 Shock	2015	Hansen ME, Simmons KJ, Tippetts TS, Thatcher MO, Saito RR, Hubbard ST, Trumbull AM, Parker BA, Taylor OJ, Bikman BT (2015) Lipopolysaccharide disrupts mitochondrial physiology in skeletal muscle via disparate effects on sphingolipid metabolism. Shock 44:585-92.	OXPHOS LEAK ET	N NS ROX	Permeabilized cells Permeabilized tissue	Mouse	Skeletal muscle Other cell lines
Warne 2015 J Biol Chem	2015	Warne J, Pryce G, Hill JM, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AWE, Towers GJ, Coker AR, Duchen MR, Szabadkai G, Baker D, Selwood DL (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Du 2015 J Biol Chem	2015	Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710.	LEAK ROUTINE OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Nervous system Islet cell;pancreas;thymus
Patil 2015 J Nutr Biochem	2015	Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.	LEAK OXPHOS ET	F N S Gp ROX	Isolated mitochondria	Mouse	Skeletal muscle Liver Fat
Porter 2015 Am J Physiol Endocrinol Metab	2015	Porter C, Hurren NM, Cotter MV, Bhattarai N, Reidy PT, Dillon EL, Durham WJ, Tuvdendorj D, Sheffield-Moore M, Volpi E, Sidossis LS, Rasmussen BB, Børsheim E (2015) Mitochondrial respiratory capacity and coupling control decline with age in human skeletal muscle. Am J Physiol Endocrinol Metab 309:E224-32.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Paeaesuke 2015 Oxid Med Cell Longev	2015	Pääsuke R, Eimre M, Piirsoo A, Peet N, Laada L, Kadaja L, Roosimaa M, Pääsuke M, Märtson A, Seppet E, Paju K (2015) Proliferation of human primary myoblasts is associated with altered energy metabolism in dependence of ageing in vivo and in vitro. Oxid Med Cell Longev 8296150:10p.	OXPHOS	N S CIV ROX	Permeabilized cells	Human	Skeletal muscle
Harris 2015 Diabetes	2015	Harris LA, Skinner JR, Shew TM, Pietka TA, Abumrad NA, Wolins NE (2015) Perilipin 5-driven lipid droplet accumulation in skeletal muscle stimulates the expression of fibroblast growth factor 21. Diabetes 64:2757-68.	OXPHOS ET	N S NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Ydfors 2015 J Physiol	2015	Ydfors M, Hughes MC, Laham R, Schlattner U, Norrbom J, Perry CG (2015) Modelling in vivo creatine/phosphocreatine in vitro reveal divergent adaptations in human muscle mitochondrial respiratory control by ADP after acute and chronic exercise. J Physiol 594:3127-40.	OXPHOS	N	Permeabilized tissue	Human	Skeletal muscle
Hollis 2015 Proc Natl Acad Sci U S A	2015	Hollis F, van der Kooij MA, Zanoletti O, Lozano L, Cantó C, Sandi C (2015) Mitochondrial function in the brain links anxiety with social subordination. Proc Natl Acad Sci U S A 112:15486-91.	OXPHOS ET	N S NS ROX	Homogenate	Rat	Nervous system
Maiti 2015 PhD Thesis	2015	Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Mouse	Heart
Baris 2015 Am J Physiol Regul Integr Comp Physiol	2015	Baris TZ, Crawford DL, Oleksiak MF (2015) Acclimation and acute temperature effects on population differences in oxidative phosphorylation. Am J Physiol Regul Integr Comp Physiol 310:R185-96.	LEAK OXPHOS ET	N S CIV NS Other combinations ROX	Permeabilized tissue	Fishes	Heart
Czerniczyniec 2015 J Bioenerg Biomembr	2015	Czerniczyniec A, Lanza EM, Karadayian AG, Bustamante J, Lores-Arnaiz S (2015) Impairment of striatal mitochondrial function by acute paraquat poisoning. J Bioenerg Biomembr 47:395-408.	LEAK OXPHOS	N ROX	Isolated mitochondria	Rat	Nervous system
Bratic 2015 Nat Commun	2015	Bratic A, Kauppila TE, Macao B, Grönke S, Siibak T, Stewart JB, Baggio F, Dols J, Partridge L, Falkenberg M, Wredenberg A, Larsson NG (2015) Complementation between polymerase- and exonuclease-deficient mitochondrial DNA polymerase mutants in genomically engineered flies. Nat Commun 6:8808.	LEAK OXPHOS ET	N	Permeabilized tissue	Drosophila Hexapods
Angebault 2015 Am J Hum Genet	2015	Angebault C, Guichet PO, Talmat-Amar Y, Charif M, Gerber S, Fares-Taie L, Gueguen N, Halloy F, Moore D, Amati-Bonneau P, Manes G, Hebrard M, Bocquet B, Quiles M, Piro-Mégy C, Teigell M, Delettre C, Rossel M, Meunier I, Preising M, Lorenz B, Carelli V, Chinnery PF, Yu-Wai-Man P, Kaplan J, Roubertie A, Barakat A, Bonneau D, Reynier P, Rozet JM, Bomont P, Hamel CP, Lenaers G (2015) Recessive mutations in RTN4IP1 cause isolated and syndromic optic neuropathies. Am J Hum Genet 97:754-60.		N S CIV NS ROX		Human	Endothelial;epithelial;mesothelial cell Fibroblast
Petrus 2015 Can J Physiol Pharmacol	2015	Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Rat	Heart
Hey-Mogensen 2015 J Physiol	2015	Hey-Mogensen M, Gram M, Jensen MB, Lund MT, Hansen CN, Scheibye-Knudsen M, Bohr VA, Dela F (2015) A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. J Physiol 593:3991-4010.	LEAK OXPHOS	N S	Isolated mitochondria	Human	Skeletal muscle
Gram 2015 J Physiol	2015	Gram M, Vigelsø A, Yokota T, Helge JW, Dela F, Hey-Mogensen M (2015) Skeletal muscle mitochondrial H₂O₂ emission increases with immobilization and decreases after aerobic training in young and older men. J Physiol 593:4011-27.	LEAK OXPHOS	N S	Isolated mitochondria	Human	Skeletal muscle
Sjoevall 2015 US Patent	2015	Sjövall F, Ehinger J, Hansson M, Elmer E, Batcheller DG (2018) Mitochondrial toxicity test. US Patent US20150253306 A1.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Macrophage-derived Platelet
Kucera 2015 Oxid Med Cell Longev	2015	Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180.	LEAK OXPHOS	N S	Isolated mitochondria Intact cells	Rat	Liver
Guadalupe-Grau 2015 J Sports Sci	2015	Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2015) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 33:570-8.	LEAK OXPHOS	F N NS Other combinations ROX	Permeabilized tissue	Human	Skeletal muscle
Tomsik 2015 J Organomet Chem	2015	Tomsík P, Muthna D, Rezacova M, Micuda S, Cmielova J, Hroch M, Endlicher R, Cervinkova Z, Rudolf E, Hann S, Stíbal D, Therrien B, Süss-Fink G (2015) [(p-MeC₆H₄Prⁱ)₂Ru₂(SC₆H₄-p-Bu^t)₃]Cl (diruthenium-1), a dinuclear arene ruthenium compound with very high anticancer activity: An in vitro and in vivo study. J Organomet Chem 782:42-51.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Liver
Van de Weijer 2015 Diabetes	2015	van de Weijer T, Phielix E, Bilet L, Williams EG, Ropelle ER, Bierwagen A, Livingstone R, Nowotny P, Sparks LM, Paglialunga S, Szendroedi J, Havekes B, Moullan N, Pirinen E, Hwang JH, Schrauwen-Hinderling VB, Hesselink MK, Auwerx J, Roden M, Schrauwen P (2015) Evidence for a direct effect of the NAD⁺ precursor acipimox on muscle mitochondrial function in humans. Diabetes 64:1193-201.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Skeletal muscle
Fritsch 2015 Am J Clin Nutr	2015	Fritsch M, Koliaki C, Livingstone R, Phielix E, Bierwagen A, Meisinger M, Jelenik T, Strassburger K, Zimmermann S, Brockmann K, Wolff C, Hwang JH, Szendroedi J, Roden M (2015) Time course of postprandial hepatic phosphorus metabolites in lean, obese, and type 2 diabetes patients. Am J Clin Nutr 102:1051-8.	OXPHOS ET	N NS		Human	Skeletal muscle
Teh 2015 Oncogene	2015	Teh JT, Zhu WL, Ilkayeva OR, Li Y, Gooding J, Casey PJ, Summers SA, Newgard CB, Wang M (2015) Isoprenylcysteine carboxylmethyltransferase regulates mitochondrial respiration and cancer cell metabolism. Oncogene 34:3296-304.	OXPHOS	N S DQ CIV ROX	Permeabilized cells	Human	Other cell lines
Tartaro 2015 Transplant Proc	2015	Tártaro RD, Jorge GD, Leonardi MI, Escanhoela CA, Leonardi LS, Boin IF (2015) No protective function found in Wistar rats submitted to long ischemia time and reperfusion after intermittent clamping of the total hepatic pedicle. Transplant Proc 47:1038-41.	LEAK OXPHOS ET	N	Intact cells	Rat	Liver
Hughes 2015 Front Physiol	2015	Hughes MC, Ramos SV, Turnbull PC, Nejatbakhsh A, Baechler BL, Tahmasebi H, Laham R, Gurd BJ, Quadrilatero J, Kane DA, Perry CG (2015) Mitochondrial bioenergetics and fiber type assessments in microbiopsy vs. Bergstrom percutaneous sampling of human skeletal muscle. Front Physiol 6:360.	OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Morato 2015 Cell Death Differ	2015	Morató L, Ruiz M, Boada J, Calingasan NY, Galino J, Guilera C, Jové M, Naudí A, Ferrer I, Pamplona R, Serrano M, Portero-Otín M, Beal MF, Fourcade S, Pujol A (2015) Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy. Cell Death Differ 22:1742-53.	LEAK OXPHOS	N S NS ROX	Permeabilized tissue	Mouse	Nervous system
Chin 2015 US Patent	2015	Chin MT, Chien WM, Dinca A (2015) Modified tafazzin proteins and methods of making and using the same. US Patent US20150203827 A1.	OXPHOS	N S CIV	Permeabilized tissue	Mouse	Skeletal muscle
Syrjanen 2015 Front Zool	2015	Syrjanen L, Valanne S, Kuuslahti M, Tuomela T, Sriram A, Sanz A, Jacobs HT, Ramet M, Parkkila S. (2015) β carbonic anhydrase is required for female fertility in Drosophila melanogaster. Front Zool 12:19.	OXPHOS	N Gp CIV Other combinations	Homogenate	Drosophila
Duicu 2015 Biomed Res Int	2015	Duicu OM, Lighezan R, Sturza A, Ceausu RA, Borza C, Vaduva A, Noveanu L, Gaspar M, Ionac A, Feier H, Muntean DM, Mornos C (2015) Monoamine oxidases as potential contributors to oxidative stress in diabetes: time for a study in patients undergoing heart surgery. Biomed Res Int 2015:515437.	LEAK OXPHOS ET	N S ROX	Permeabilized tissue	Human	Heart
Ferrera 2015 J Thorac Cardiovasc Surg	2015	Ferrera R, Benhabbouche S, Da Silva CC, Alam MR, Ovize M (2015) Delayed low pressure at reperfusion: A new approach for cardioprotection. J Thorac Cardiovasc Surg 150:1641-8.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol	2015	Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57.	LEAK ROUTINE OXPHOS ET	N CIV Other combinations	Isolated mitochondria Intact cells	Human Bovines	Endothelial;epithelial;mesothelial cell Fibroblast
Valet 2015 US Patent	2015	Valet P, Dray C, Knauf C, Kunduzova O, Castan-Laurell I (2015) Pharmaceutical composition for use in the treatment of dysfunction associated with aging. US Patent US20150290286 A1.	OXPHOS	N S	Permeabilized tissue	Mouse	Skeletal muscle
Diana 2015 Surg Innov	2015	Diana M, Noll E, Diemunsch P, Moussallieh FM, Namer IJ, Charles AL, Lindner V, Agnus V, Geny B, Marescaux J (2015) Metabolism-guided bowel resection: potential role and accuracy of instant capillary lactates to identify the optimal resection site. Surg Innov 22:453-61.	LEAK OXPHOS	N S CIV		Pig	Endothelial;epithelial;mesothelial cell
Bock 2015 Thesis	2015	Bock UB (2015) Auswirkung von normobarer Hyperoxie auf die mitochondriale Atmung von Alveolarmakrophagen. Dissertation p80.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Mouse	Lung;gill Macrophage-derived
Dungel 2015 Free Radic Biol Med	2015	Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.	LEAK OXPHOS ET	N S	Isolated mitochondria	Rat	Liver
Doerrier 2015 Thesis	2015	Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.	LEAK OXPHOS ET	N S NS	Permeabilized tissue Isolated mitochondria	Mouse	Heart Liver
Saraf 2015 J Burn Care Res	2015	Saraf MK, Herndon DN, Porter C, Toliver-Kinsky T, Radhakrishnan R, Chao T, Chondronikola M, Sidossis LS (2015) Morphological changes in subcutaneous white adipose tissue after severe burn injury. J Burn Care Res 37:e96-e103.	LEAK OXPHOS	F N Other combinations	Permeabilized tissue	Human	Fat
Lehtola 2015 Master's Thesis	2015	Lehtola A (2015) Main protein component of high density lipoprotein, apolipoprotein A1, modulates leukocyte cell respiration. Master's Thesis 1-44.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Intact cells Permeabilized cells	Human	Blood cells Other cell lines Lymphocyte
Whitfield 2015 J Physiol	2015	Whitfield J, Ludzki A, Heigenhauser GJ, Senden JM, Verdijk LB, van Loon LJ, Spriet LL, Holloway GP (2015) Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle. J Physiol 594:421-35.	LEAK OXPHOS	N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Banerjee 2015 Placenta	2015	Banerjee A, Weidinger A, Hofer M, Steinborn R, Lindenmair A, Hennerbichler-Lugscheider S, Eibl J, Redl H, Kozlov AV, Wolbank S (2015) Different metabolic activity in placental and reflected regions of the human amniotic membrane. Placenta 36:1329-32.	ROUTINE OXPHOS ET	N	Intact cells Permeabilized tissue	Human	Genital
Miwa 2015 Free Radic Biol Med	2015	Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H₂O₂ release assays. Free Radic Biol Med 90:173-83.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Liver
Coen 2015 Diabetes	2015	Coen PM, Menshikova EV, Distefano G, Zheng D, Tanner CJ, Standley RA, Helbling NL, Dubis GS, Ritov VB, Xie H, Desimone ME, Smith SR, Stefanovic-Racic M, Toledo FG, Houmard JA, Goodpaster BH (2015) Exercise and weight loss improve muscle mitochondrial respiration, lipid partitioning, and insulin sensitivity after gastric bypass surgery. Diabetes 64:3737-50.	LEAK OXPHOS ET	F N NS Other combinations	Permeabilized tissue	Human	Skeletal muscle
Ofer 2015 Mol Endocrinol	2015	Ofer P, Heidegger I, Eder IE, Schöpf B, Neuwirt H, Geley S, Klocker H, Massoner P (2015) Both IGF1R and INSR knockdown exert anti-tumorigenic effects in prostate cancer in vitro and in vivo. Mol Endocrinol 29:1694-707.	ROUTINE OXPHOS ET	F N NS	Permeabilized cells Intact cells	Human	Genital Other cell lines
Hals 2015 PLoS One	2015	Hals IK, Bruerberg SG, Ma Z, Scholz H, Björklund A, Grill V (2015) Mitochondrial respiration in insulin-producing β-cells: general characteristics and adaptive effects of hypoxia. PLoS One 10:e0138558.	LEAK ROUTINE OXPHOS ET	N S NS ROX	Permeabilized cells Intact cells	Rat	Islet cell;pancreas;thymus Other cell lines
Boushel 2015 Scand J Med Sci Sports	2015	Boushel R, Gnaiger E, Larsen FJ, Helge JW, Gonzalez-Alonso J, Ara I, Munch-Andersen T, van Hall G, Søndergaard H, Saltin B, Calbet JAL (2015) Maintained peak leg and pulmonary V_O2 despite substantial reduction in muscle mitochondrial capacity. Scand J Med Sci Sports 25 (Suppl 4):135–43.	OXPHOS	F N S NS	Intact organ Permeabilized tissue	Human	Skeletal muscle
Antoun 2015 JIMD Rep	2015	Antoun G, McBride S, Vanstone JR, Naas T, Michaud J, Redpath S, McMillan HJ, Brophy J, Daoud H, Chakraborty P, Dyment D, Holcik M, Harper ME, Lines MA (2015) Detailed biochemical and bioenergetic characterization of FBXL4-related encephalomyopathic mitochondrial DNA depletion. JIMD Rep 27:1-9.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Human	Skeletal muscle
Ziemer 2015 Dissertation	2015	Ziemer M (2015) Untersuchungen zur Aktivität der mitochondrialen Permeabilitätstransitionspore in der Cyclophilin-D-Knock-out-Maus (Ppif^-/-). Dissertation 1-72.	LEAK OXPHOS	N	Isolated mitochondria	Mouse	Liver
Woodlief 2015 Obesity (Silver Spring)	2015	Woodlief TL, Carnero EA, Standley RA, Distefano G, Anthony SJ, Dubis GS, Jakicic JM, Houmard JA, Coen PM, Goodpaster BH (2015) Dose response of exercise training following roux-en-Y gastric bypass surgery: A randomized trial. Obesity (Silver Spring) 23:2454-61.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Burtscher 2015 Mitochondrion	2015	Burtscher J, Zangrandi L, Schwarzer C, Gnaiger E (2015) Differences in mitochondrial function in homogenated samples from healthy and epileptic specific brain tissues revealed by high-resolution respirometry. Mitochondrion 25:104-12.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue Homogenate	Mouse	Nervous system
Herbst 2015 Neuroscience	2015	Herbst EA, Holloway GP (2015) Exercise training normalizes mitochondrial respiratory capacity within the striatum of the R6/1 model of Huntington's disease. Neuroscience 303:515-23.	OXPHOS	N S NS	Permeabilized tissue	Mouse	Nervous system
Herbst 2015 Metabolism	2015	Herbst EA, Roussakis C, Matravadia S, Holloway GP (2015) Chronic treadmill running does not enhance mitochondrial oxidative capacity in the cortex or striatum. Metabolism 64:1419-25.	LEAK OXPHOS	N NS	Permeabilized tissue	Mouse	Skeletal muscle Nervous system
Weidinger 2015 Antioxid Redox Signal	2015	Weidinger A, Müllebner A, Paier-Pourani J, Banerjee A*, Miller I, Lauterböck L, Duvigneau JC, Skulachev VP, Redl H, Kozlov AV (2015) Vicious inducible nitric oxide synthase-mitochondrial reactive oxygen species cycle accelerates inflammatory response and causes liver injury in rats. Antioxid Redox Signal 22:572-86.	LEAK OXPHOS ET	N S	Homogenate	Rat	Liver
Clemens 2015 Brain	2015	Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Rat	Nervous system
Gnaiger 2015 Scand J Med Sci Sports	2015	Gnaiger E, Boushel R, Søndergaard H, Munch-Andersen T, Damsgaard R, Hagen C, Díez-Sánchez C, Ara I, Wright-Paradis C, Schrauwen P, Hesselink M, Calbet JAL, Christiansen M, Helge JW, Saltin B (2015) Mitochondrial coupling and capacity of oxidative phosphorylation in skeletal muscle of Inuit and caucasians in the arctic winter. https://doi.org/10.1111/sms.12612	LEAK OXPHOS ET	F N S ROX	Permeabilized tissue	Human	Skeletal muscle
Schirris 2015 Cell Metab	2015	Schirris TJ, Renkema GH, Ritschel T, Voermans NC, Bilos A, van Engelen BG, Brandt U, Koopman WJ, Beyrath JD, Rodenburg RJ, Willems PH, Smeitink JA, Russel FG (2015) Statin-induced myopathy is associated with mitochondrial complex III inhibition. Cell Metab 22:399-407.	ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells	Human Mouse	Skeletal muscle Other cell lines
Crombie 2015 Biochem Biophys Rep	2015	Crombie DE, van Bergena N, Davidsona KC, Anjomani Virmounib S, Mckelviec PA, Chrysostomoua V, Conquesta A, Corbend LA, Pookb MA, Kulkarnia T, Trouncea IA, Peraf MF, Delatyckid MB, Pébaya A (2015) Characterization of the retinal pigment epithelium in Friedreich ataxia. Biochem Biophys Rep 4:141–7.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells	Human	Nervous system Endothelial;epithelial;mesothelial cell Stem cells
Hansen 2015 Obesity (Silver Spring)	2015	Hansen M, Lund MT, Gregers E, Kraunsøe R, Van Hall G, Helge JW, Dela F (2015) Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB. Obesity (Silver Spring) 23:2022-9.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Human	Fat
Assmann 2014 PhD Thesis	2015	Assmann N (2015) Impact of Fanconi-associated protein on the mitochonrial proteome. PhD Thesis 1-111.	LEAK ROUTINE OXPHOS ET	F N S CIV NS ROX	Permeabilized cells Intact cells	Pig	Kidney Other cell lines
Wessels 2015 Am J Physiol	2015	Wessels B, van den Broek NM, Ciapaite J, Houten SM, Wanders RJA, Nicolay K, Prompers JJ (2015) Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo. Am J Physiol 309(7):E670-8.	LEAK OXPHOS ET	F N	Isolated mitochondria	Rat	Skeletal muscle
Kruse 2015 Aging Cell	2015	Kruse SE, Karunadharma PP, Basisty N, Johnson R, Beyer RP, MacCoss MJ, Rabinovitch PS, Marcinek DJ (2015) Age modifies respiratory complex I and protein homeostasis in a muscle type-specific manner. Aging Cell 15:89-99.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized tissue	Mouse	Skeletal muscle
Canto 2015 Curr Protoc Mouse Biol	2015	Cantó C, Garcia-Roves PM (2015) High-resolution respirometry for mitochondrial characterization of ex vivo mouse tissues. Curr Protoc Mouse Biol 5:135-53.	LEAK OXPHOS ET	N S NS	Permeabilized tissue Homogenate	Mouse	Heart Skeletal muscle Nervous system Liver Fat
Kishita 2015 Am J Hum Genet	2015	Kishita Y, Pajak A, Bolar NA, Marobbio CM, Maffezzini C, Miniero DV, Monné M, Kohda M, Stranneheim H, Murayama K, Naess K, Lesko N, Bruhn H, Mourier A, Wibom R, Nennesmo I, Jespers A, Govaert P, Ohtake A, Van Laer L, Loeys BL, Freyer C, Palmieri F, Wredenberg A, Okazaki Y, Wedell A (2015) Intra-mitochondrial methylation deficiency due to mutations in SLC25A26. Am J Hum Genet 97:761-8.	OXPHOS ET	N NS		Human	Skeletal muscle Fibroblast
Van Ewijk 2015 Obesity (Silver Spring)	2015	van Ewijk PA, Paglialunga S, Kooi ME, Nunes PM, Gemmink A, Slenter J, Kornips E, Jörgensen JA, Hoeks J, Wildberger JE, Hesselink MK, Glatz JF, Heerschap A, Kersten S, Schrauwen P, Schrauwen-Hinderling VB (2015) Effects of high-fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring. Obesity (Silver Spring) 23:2242-50.	LEAK OXPHOS	F N	Isolated mitochondria	Mouse	Heart Liver
Boutant 2014 Mol Metab	2014	Boutant M, Joffraud M, Kulkarni SS, Garcia-Casarrubios E, Garcia-Roves PM, Ratajczak J, Fernandez-Marcos PJ, Valverde AM, Serrano M, Canto C (2014) SIRT1 enhances glucose tolerance by potentiating brown adipose tissue function. Mol Metab 4:118-31.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue Homogenate	Mouse	Skeletal muscle Liver Fat
Nigro 2014 Endocrinology	2014	Nigro M, Santos AT, Barthem CS, Louzada RA, Fortunato RS, Ketzer LA, Carvalho DP, de Meis L (2014) A change in liver metabolism but not in brown adipose tissue thermogenesis is an early event in ovariectomy-induced obesity in rats. Endocrinology 155:2881-91.	OXPHOS	N	Isolated mitochondria	Rat	Fat
Jelenik 2014 Diabetes	2014	Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67.	OXPHOS ET	N NS ROX	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle Liver
Montaigne 2014 Circulation	2014	Montaigne D, Marechal X, Coisne A, Debry N, Modine T, Fayad G, Potelle C, El Arid JM, Mouton S, Sebti Y, Duez H, Preau S, Remy-Jouet I, Zerimech F, Koussa M, Richard V, Neviere R, Edme JL, Lefebvre P, Staels B (2014) Myocardial contractile dysfunction is associated with impaired mitochondrial function and dynamics in Type 2 Diabetic but not in obese patients. Circulation 130:554-64.	LEAK OXPHOS ET	F N S CIV NS	Permeabilized tissue	Human	Heart
Littlejohns 2014 PLoS One	2014	Littlejohns B, Pasdois P, Duggan S, Bond AR, Heesom K, Jackson CL, Angelini GD, Halestrap AP, Suleiman MS (2014) Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. PLoS One 9:e100579.	LEAK OXPHOS	F N	Isolated mitochondria	Mouse	Heart
Pham 2014 Am J Physiol	2014	Pham T, Loiselle D, Power A, Hickey AJ (2014) Mitochondrial inefficiencies and anoxic ATP hydrolysis capacities in diabetic rat heart. Am J Physiol 307:C499–507.	LEAK OXPHOS ET	N NS ROX	Homogenate	Rat	Heart
Wessels 2014 PLoS One	2014	Wessels B, Ciapaite J, van den Broek NMA, Nicolay K, Prompers JJ (2014) Metformin impairs mitochondrial function in skeletal muscle of both lean and diabetic rats in a dose-dependent manner. PLoS One 9:e100525.	LEAK OXPHOS ET	N S	Isolated mitochondria	Rat	Skeletal muscle
Damiano 2014 PLoS One	2014	Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A (2014) Tissue- and cell-specific mitochondrial defect in Parkin- deficient mice. PLoS One 9:e99898.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Nervous system
Chu 2014 PLoS One	2014	Chu MJ, Hickey AJ, Tagaloa S, Zhang L, Dare AJ, MacDonald JR, Yeong ML, Bartlett AS, Phillips AR (2014) Ob/ob mouse livers show decreased oxidative phosphorylation efficiencies and anaerobic capacities after cold ischemia. PLoS One 9:e100609.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue	Mouse	Liver
Preau 2014 Thesis University Lille	2014	Preau S (2014) Implication du cytosquelette dans les dysfonctions myocardiques : exemple de la cardiomyopathie septique. Thesis University Lille 155pp.	LEAK OXPHOS	N S	Permeabilized tissue	Mouse	Heart
Kancirova 2014 Cardiovasc Res	2014	Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I, Ziegelhoffer A, Ferko M (2014) P406Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovasc Res 103 Suppl 1:S74-5.	OXPHOS	F N	Isolated mitochondria	Rat	Heart
Furlanetto 2014 Thesis University of Parana	2014	Furlanetto ALD de Matos (2014) Estresse oxidativo e transição de permeabilidade mitocondrial em células embriogênicas somáticas de Auraucária angustifolia estressadas pelo frio. Thesis University of Parana 53pp.	LEAK OXPHOS	N	Isolated mitochondria	Plants
Ryan 2014 J Physiol	2014	Ryan TE, Brophy P, Lin CT, Hickner RC, Neufer PD (2014) Assessment of in vivo skeletal muscle mitochondrial respiratory capacity in humans by near-infrared spectroscopy: a comparison with in situ measurements. J Physiol 592:3231-41.	LEAK OXPHOS	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Williams 2014 PLoS One	2014	Williams CB, Hughes MC, Edgett BA, Scribbans TD, Simpson CA, Perry CG, Gurd BJ (2014) An examination of resveratrol's mechanisms of action in human tissue: impact of a single dose in vivo and dose responses in skeletal muscle ex vivo. PLoS One 9:e102406.	OXPHOS	F N S NS	Permeabilized tissue	Human	Skeletal muscle
Afshordel 2014 Prostaglandins Leukot Essent Fatty Acids	2014	Afshordel S, Hagl S, Werner D, Roehner N, Koegel D, Bazan NG, Eckert GP (2014) Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - impact of Bcl-2 and NPD-1 like metabolites. Prostaglandins Leukot Essent Fatty Acids 92:23-31.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Abdurrachim 2014 Biochim Biophys Acta	2014	Abdurrachim D, Ciapaite J, Wessels B, Nabben M, Luiken JJ, Nicolay K, Prompers JJ (2014) Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochim Biophys Acta 1842:1525-37.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Heart
Ambrosio 2014 Free Radic Biol Med	2014	Ambrosio F, Brown E, Stolz D, Ferrari R, Goodpaster BH, Deasy B, Distefano G, Roperti A, Cheikhi A, Garciafigueroa Y, Barchowsky A (2014) Arsenic induces sustained impairment of skeletal muscle and muscle progenitor cell ultrastructure and bioenergetics. Free Radic Biol Med 74C:64-73.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Elustondo 2014 Biochim Biophys Acta	2014	Elustondo PA, Negoda A, Kane CL, Kane DA, Pavlov EV (2014) Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore. Biochim Biophys Acta 1847:231–40.	LEAK	N	Isolated mitochondria	Rat	Liver
Sims 2014 FASEB J	2014	Sims C, Patil N, MacMillian-Crow LA, Mayeux P (2014) Mitochondrial superoxide generation in the rat pup kidney during sepsis. FASEB J 28:1063.7.		N CIV NS	Permeabilized tissue	Rat
Stokich 2014 Cryobiology	2014	Stokich B, Osgood Q, Grimm D, Moorthy S, Chakraborty N, Menze MA (2014) Cryopreservation of hepatocyte (HepG2) cell monolayers: Impact of trehalose. Cryobiology 69:281-90.	LEAK OXPHOS	N S NS ROX	Permeabilized cells	Human	Liver
Kancirova 2014 Cardiovascular Research Supplements	2014	Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I. Ziegelhoffer A, Ferko M (2014) Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovascular Research Supplements 103:57–94.	OXPHOS	F N	Isolated mitochondria	Rat	Heart
Gram 2014 Exp Gerontol	2014	Gram M, Vigelsoe A, Yokota T, Hansen CN, Helge JW, Hey-Mogensen M, Dela F (2014) Two weeks of one-leg immobilization decreases skeletal muscle 2 respiratory capacity equally in young and elderly men. Exp Gerontol 58C:269-78.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Stenberg 2014 PLoS One	2014	Stenberg TA, Kildal AB, Sanden E, How OJ, Hagve M, Ytrehus K, Larsen TS, Myrmel T (2014) The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations. PLoS One 9:e105213.	LEAK OXPHOS	N S	Isolated mitochondria	Pig	Heart Liver Kidney
Kaldma 2014 Int J Biochem Cell Biol	2014	Kaldma A, Klepinin A, Chekulayev V, Mado K, Shevchuk I, Timohhina N, Tepp K, Kandashvili M, Varikmaa M, Koit A, Planken M, Heck K, Truu L, Planken A, Valvere V, Rebane E, Kaambre T (2014) An in situ study of bioenergetic properties of human colorectal cancer: The regulation of mitochondrial respiration and distribution of flux control among the components of ATP synthasome. Int J Biochem Cell Biol 55C:171-86.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized tissue	Human	Genital
Fisar 2014 Toxicol Lett	2014	Fišar Z, Singh N, Hroudová J (2014) Cannabinoid-induced changes in respiration of brain mitochondria. Toxicol Lett 231:62-71.	LEAK OXPHOS ET	N S CIV ROX	Isolated mitochondria	Pig	Nervous system
Jiroutkova 2014 Intensive Care Medicine Experimental	2014	Jiroutkova K, Ziak J, Krajcova A, Fric M, Dzupa V, Duska F (2014) The role of mitochondrial dysfunction in the pathophysiology of icu-acquired weakness. Intensive Care Med 2:29.	LEAK OXPHOS ET	N S		Human	Skeletal muscle
Garnol 2014 Physiol Res	2014	Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.	LEAK OXPHOS ET	N S	Permeabilized cells Isolated mitochondria Intact cells	Rat	Liver
Guadalupe-Grau 2014 J Sports Sci	2014	Guadalupe-Grau A, Plenge U, Helbo S, Kristensen M, Andersen PR, Fago A, Belhage B, Dela F, Helge JW (2014) Effects of an 8-weeks erythropoietin treatment on mitochondrial and whole body fat oxidation capacity during exercise in healthy males. J Sports Sci 26:1-9.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Thatcher 2014 Am J Physiol Endocrinol Metab	2014	Thatcher MO, Tippetts TS, Nelson MB, Swensen AC, Winden DR, Hansen ME, Anderson MC, Johnson IE, Porter JP, Reynolds PR, Bikman BT (2014) Ceramides mediate cigarette smoke-induced metabolic disruption in mice. Am J Physiol Endocrinol Metab 307:E919-27.	LEAK OXPHOS ET	N S NS ROX	Permeabilized cells Permeabilized tissue	Human Mouse	Skeletal muscle
Scandroglio 2014 Free Radic Res	2014	Scandroglio F, Tortora V, Radi R, Castro L (2014) Metabolic control analysis of mitochondrial aconitase: influence over respiration and mitochondrial superoxide and hydrogen peroxide production. Free Radic Res 48:684-93.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Heart Nervous system Liver Kidney
Serteyn 2014 Bioenergetics	2014	Serteyn D, de la Rebière de Pouyade G, Sandersen C, Salciccia A, Grulke S, Mouithys-Mickalad A, Franck T, Lejeune JP, Ceusters Justine D (2014) Muscle mitochondrial dysfunction in horses affected by acute laminitis. Bioenergetics 3:1-7.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Horse	Skeletal muscle
Rudnicki 2014 United States Patent Application Publication	2014	Rudnicki MA, Yin Hang (2014) MICRORNA INHIBITORS. United States Patent Application Publication 1-49.	LEAK ROUTINE OXPHOS ET	F N S NS ROX	Permeabilized cells Intact cells	Mouse	Skeletal muscle Fat
Iglesias-Gonzalez 2014 PhD Thesis	2014	Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242.	LEAK OXPHOS ET	N S NS ROX	Isolated mitochondria	Rat	Nervous system
Zambrano 2014 J Cell Biol	2014	Zambrano A, García-Carpizo V, Gallardo ME, Villamuera R, Gómez-Ferrería MA, Pascual A, Buisine N, Sachs LM, Garesse R, Aranda A (2014) The thyroid hormone receptor induces DNA damage and premature senescence. J Cell Biol 204:129-46.	LEAK OXPHOS ET	N ROX	Intact cells	Mouse
Rossato 2014 PLoS One	2014	Rossato FA, Zecchin KG, La Guardia PG, Ortega RM, Alberici LC, Costa RA, Catharino RR, Graner E, Castilho RF, Vercesi AE (2014) Fatty acid synthase inhibitors induce apoptosis in non-tumorigenic Melan-A cells associated with inhibition of mitochondrial respiration. PLoS One 9:e101060.	LEAK OXPHOS ET	N S CIV NS	Permeabilized cells Intact cells	Mouse	Endothelial;epithelial;mesothelial cell Other cell lines
Ludzki 2014 Thesis	2014	Ludzki AC (2014) Palmitoyl-CoA inhibition of mitochondrial ADP sensitivity is attenuated by exercise training in human skeletal muscle. Master's Thesis 1-86.	LEAK OXPHOS	F N S Gp NS	Permeabilized tissue	Human Mouse	Skeletal muscle
Koenemann 2014 Dissertation	2014	Koenemann B (2014) Einfluss der Hyperglykämie auf die mitochondriale Atmung von Leberzellen septischer Mäuse mit und ohne Imeglimin. PhD Thesis 1-61.	LEAK OXPHOS ET	F N S NS Other combinations ROX	Homogenate	Mouse	Liver
Garcia-Corzo 2014 Thesis	2014	García-Corzo L (2014) Fisiopatologia de la deficiencia en CoQ: evaluacion de terapias con la mitocondria como diana terapeutica. Doctoral Thesis p182.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Heart Skeletal muscle Nervous system Kidney
Li 2014 Mol Cell Biol	2014	Li S, Yao Y, Xu R, Pesenti S, Cottet-Rousselle C, Rieusset J, Tokarska-Schlattner M, Liao K, Schlattner U, Rousseau D (2014) ATAD3 is a limiting factor in mitochondrial biogenesis and adipogenesis of white adipocyte-like 3T3-L1 cells. Mol Cell Biol 37.	LEAK OXPHOS	N S	Permeabilized cells	Mouse	Fat Other cell lines
Khan 2014 J Comp Physiol	2014	Khan JR, Iftikar FI, Herbert NA, Gnaiger E, Hickey AJ (2014) Thermal plasticity of skeletal muscle mitochondrial activity and whole animal respiration in a common intertidal triplefin fish, Forsterygion lapillum (Family: Tripterygiidae). J Comp Physiol 184:991-1001.	LEAK OXPHOS ET	N S NS ROX	Permeabilized tissue	Fishes	Skeletal muscle
Slinde 2014 freepatentsonline.com	2014	Slinde E, Egelandsdal B (2014) Meat treatment and preservation method. Freepatentsonline.com 14/128207.	LEAK OXPHOS ET	F N NS ROX	Permeabilized tissue	Bovines	Skeletal muscle
Lou 2014b PLoS One	2014	Lou PH, Lucchinetti E, Zhang L, Affolter A, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) Loss of Intralipid®- but not sevoflurane-mediated cardioprotection in early type-2 diabetic hearts of fructose-fed rats: importance of ROS signaling. PLoS One 9:e104971.	LEAK	F N S CIV	Permeabilized tissue	Rat	Heart
Herbst 2014 J Physiol	2014	Herbst EA, Paglialunga S, Gerling C, Whitfield J, Mukai K, Chabowski A, Heigenhauser GJ, Spriet LL, Holloway GP (2014) Omega-3 supplementation alters mitochondrial membrane composition and respiration kinetics in human skeletal muscle. J Physiol 592:1341-52.	OXPHOS	N	Permeabilized tissue	Human	Skeletal muscle
Soltysinska 2014 PLoS One	2014	Soltysinska E, Bentzen BH, Barthmes M, Hattel H, Thrush AB, Harper ME, Qvortrup K, Larsen FJ, Schiffer TA, Losa-Reyna J, Straubinger J, Kniess A, Thomsen MB, Brüggemann A, Fenske S, Biel M, Ruth P, Wahl-Schott C, Boushel RC, Olesen SP, Lukowski R (2014) KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. PLoS One 9:e103402.	LEAK OXPHOS	N NS ROX	Permeabilized tissue Isolated mitochondria	Mouse	Heart Skeletal muscle
Cedikova 2014 Evid Based Complement Alternat Med	2014	Cedikova M, Miklikova M, Stachova L, Grundmanova M, Tuma Z, Vetvicka V, Zech N, Kralickova M, Kuncova J (2014) Effects of the Czech propolis on sperm mitochondrial function. Evid Based Complement Alternat Med 248768.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized cells	Human	Genital
Porter 2014 Am J Physiol	2014	Porter C, Herndon DN, Børsheim E, Chao T, Reidy P, Borack M, Rasmussen BB, Chondronikola M, Saraf M, Sidossis LS (2014) Uncoupled skeletal muscle mitochondria contribute to hypermetabolism in severely burned adults. Am J Physiol 307:E462-7.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Human	Skeletal muscle
Takahashi 2014 Exp Gerontol	2014	Takahashi K, Noda Y, Ohsawa I, Shirasawa T, Takahashi M (2014) Extended lifespan, reduced body size and leg skeletal muscle mass, and decreased mitochondrial function in clk-1 transgenic mice. Exp Gerontol 58:146-53.	LEAK OXPHOS	N NS	Isolated mitochondria	Mouse	Skeletal muscle Liver
Hagl 2014 J Alzheimers Dis b	2014	Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3.	LEAK OXPHOS ET	N S CIV NS ROX	Isolated mitochondria	Mouse	Nervous system
Iftikar 2014 Thesis University of Auckland	2014	Iftikar FI (2014) Testing the role of heart mitochondrial stability and function in heart failure of ectotherms exposed to heat stress. Thesis University of Auckland:167pp.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized tissue	Fishes	Heart
Gjessing 2014 Thesis University of Tromso	2014	Gjessing PF (2014) Postoperative insulin resistance and the metabolic and cellular responses to single-dose preoperative oral carbohydrate supplementation. Thesis University of Tromso 102 pp.	LEAK OXPHOS	F N	Isolated mitochondria	Pig	Skeletal muscle Liver
Onukwufor 2013 J Exp Biol	2014	Onukwufor JO, Macdonald N, Kibenge F, Stevens D, Kamunde C (2013) Hypoxia-cadmium interactions on rainbow trout (Oncorhynchus mykiss) mitochondrial bioenergetics: attenuation of hypoxia-induced proton leak by low doses of cadmium. J Exp Biol 217:831-40.	LEAK OXPHOS ET	N	Isolated mitochondria	Fishes	Liver
Varikmaa 2014 Biochim Biophys Acta	2014	Varikmaa M, Bagur R, Kaambre T, Grichine A, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Metsis M, Boucher F, Saks V, Kuznetsov AV, Guzun R (2014) Role of mitochondria-cytoskeleton interactions in respiration regulation and mitochondrial organization in striated muscles. Biochim Biophys Acta 1837:232-45.	LEAK OXPHOS	N CIV	Permeabilized cells Isolated mitochondria	Rat	Heart Skeletal muscle
Larsen 2014 Biochim Biophys Acta	2014	Larsen S, Díez-Sánchez C, Rabøl R, Royo IA, Dela F, Helge JW (2014) Increased intrinsic mitochondrial function in humans with mitochondrial haplogroup H. Biochim Biophys Acta 1837:226-31.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Human	Skeletal muscle
Chakraborty 2014 J Cardiovasc Dis	2014	Chakraborty M, Phillips ARJ, Macdonald J, Windsor JA, Hickey AJR (2014) Mitochondrial respiration in mononuclear cells and heart fibers in spontaneously hypertensive rats. J Cardiovasc Dis ISSN:2330-459.	LEAK ROUTINE OXPHOS ET	N S Gp CIV NS ROX	Permeabilized cells Permeabilized tissue	Rat	Heart Blood cells
Beaudoin 2014 J Physiol	2014	Beaudoin MS, Perry CC, Arkell A, Chabowski A, Simpson JA, Wright DC, Holloway GP (2014) In the ZDF rat, impairments in mitochondrial palmitoyl-CoA respiratory kinetics that precede the development of diabetic cardiomyopathy are prevented by resveratrol supplementation. J Physiol 592:2519-33.	LEAK OXPHOS	N	Permeabilized tissue	Rat	Heart
Echevarría 2014 Biochem J	2014	Echevarría L, Clemente P, Hernández Sierra R, Gallardo ME, Fernández-Moreno MA, Garesse R (2014) Mammalian GatCAB is essential for mitochondrial translation 1 Glutamyl-tRNAGln amidotransferase is essential for mammalian mitochondrial translation in vivo. Biochem J 460:91-101.	LEAK ET	N	Intact cells	Human Mouse	Other cell lines HEK HeLa
Hoevenaars 2014 Mol Nutr Food Res	2014	Hoevenaars FP, Bekkenkamp-Grovenstein M, Janssen RJ, Heil SG, Bunschoten A, Hoek-van den Hil EF, Snaas-Alders S, Teerds K, van Schothorst EM, Keijer J (2014) Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences. Mol Nutr Food Res 58:799-807.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Mouse	Skeletal muscle
Kupsch 2014 J Neural Transm	2014	Kupsch A, Schmidt W, Gizatullina Z, Debska-Vielhaber G, Voges J, Striggow F, Panther P, Schwegler H, Heinze HJ, Vielhaber S, Gellerich FN (2014) 6-Hydroxydopamine impairs mitochondrial function in the rat model of Parkinson's disease: respirometric, histological, and behavioral analyses. J Neural Transm 121:1245-57.	LEAK OXPHOS	N S Gp	Permeabilized tissue	Rat	Nervous system
Castelein 2014 Exp Gerontol	2014	Castelein N, Muschol M, Dhondt I, Cai H, De Vos WH, Dencher NA, Braeckman BP (2014) Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans. Exp Gerontol 56:26-36.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Caenorhabditis elegans
Boushel 2014 Acta Physiol (Oxf)	2014	Boushel RC, Ara I, Gnaiger E, Helge JW, Gonzalez-Alonzo J, Munck-Andersen T, Sondergaard H, Damsgaard R, van Hall G, Saltin B, Calbet JA (2014) Low intensity training increases peak arm V_O₂ by enhancing both convective and diffusive O₂ delivery. Acta Physiol (Oxf) 211:122-34.	LEAK OXPHOS	F N NS	Permeabilized tissue	Human	Skeletal muscle
Patil 2014 Am J Physiol Renal Physiol	2014	Patil NK, Parajuli N, Macmillan-Crow LA, Mayeux PR (2014) Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria targeted antioxidant mitigates injury. Am J Physiol Renal Physiol 306:F734-43.	LEAK OXPHOS	N S CIV	Permeabilized tissue	Mouse	Kidney
Lou 2014 PLoS One	2014	Lou PH, Lucchinetti E, Zhang L, Affolter A, Schaub MC, Gandhi M, Hersberger M, Warren BE, Lemieux H, Sobhi HF, Clanachan AS, Zaugg M (2014) The mechanism of intralipid®-mediated cardioprotection Complex IV inhibition by the active metabolite, palmitoylcarnitine, generates reactive oxygen species and activates reperfusion injury salvage kinases. PLoS One 9:e87205.	LEAK OXPHOS	N NS	Permeabilized tissue	Rat	Heart
Casanova 2014 Biochim Biophys Acta	2014	Casanova E, Baselga-Escudero L, Ribas-Latre A, Arola-Arnal A, Bladé C, Arola L, Salvadó MJ (2014) Epigallocatechin gallate counteracts oxidative stress in docosahexaenoxic acid-treated myocytes. Biochim Biophys Acta 1837:783-91.	LEAK ROUTINE ET	N	Intact cells	Rat	Skeletal muscle Other cell lines
Krumschnabel 2014 Methods Enzymol	2014	Krumschnabel G, Eigentler A, Fasching M, Gnaiger E (2014) Use of safranin for the assessment of mitochondrial membrane potential by high-resolution respirometry and fluorometry. Methods Enzymol 542:163-81. https://doi.org/10.1016/B978-0-12-416618-9.00009-1	LEAK OXPHOS ET	N S ROX	Homogenate	Mouse	Nervous system
Solinas 2014 Mech Ageing Dev	2014	Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4.	LEAK OXPHOS ET	N S CIV NS	Isolated mitochondria	Rat	Kidney
Davoudi 2014 PLoS One	2014	Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Liver
Phielix 2014 Diabetologia	2014	Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81.	LEAK OXPHOS ET	N NS	Permeabilized tissue Isolated mitochondria	Human	Skeletal muscle
Morand 2014 Eur J Nutr	2014	Morand R, Bouitbir J, Felser A, Hench J, Handschin C, Frank S, Krähenbühl S (2014) Effect of carnitine, acetyl-, and propionylcarnitine supplementation on the body carnitine pool, skeletal muscle composition, and physical performance in mice. Eur J Nutr 53:1313-25.	LEAK OXPHOS	N S CIV	Permeabilized tissue	Mouse	Skeletal muscle
Gouspillou 2014 FASEB J	2014	Gouspillou G, Sgarioto N, Kapchinsky S, Purves-Smith F, Norris B, Pion CH, Barbat-Artigas S, Lemieux F, Taivassalo T, Morais JA, Aubertin-Leheudre M, Hepple RT (2014) Increased sensitivity to mitochondrial permeability transition and myonuclear translocation of endonuclease G in atrophied muscle of physically active older humans. FASEB J 28:1621-33.	LEAK OXPHOS	N NS	Permeabilized tissue	Human	Skeletal muscle
Tufi 2014 Nat Cell Biol	2014	Tufi R, Gandhi S, de Castro IP, Lehmann S, Angelova PR, Dinsdale D, Deas E, Plun-Favreau H, Nicotera P, Abramov AY, Willis AE, Mallucci GR, Loh SH, Martins LM (2014) Enhancing nucleotide metabolism protects against mitochondrial dysfunction and neurodegeneration in a PINK1 model of Parkinson's disease. Nat Cell Biol 16:157-66.	OXPHOS	N S CIV	Homogenate	Drosophila
Mandò 2014 Am J Physiol Endocrinol Metab	2014	Mandò C, De Palma C, Stampalija T, Anelli GM, Figus M, Novielli C, Parisi F, Clementi E, Ferrazzi E, Cetin I (2014) Placental mitochondrial content and function in intrauterine growth restriction and preeclampsia. Am J Physiol Endocrinol Metab 306:E404-13.	ROUTINE OXPHOS	N S CIV NS ROX	Intact cells Permeabilized cells	Human	Genital
De Sousa 2014 Stem Cells	2014	De Sousa M, Porras DP, Perry CG, Seale P, Scimè A. (2014) p107 is a crucial regulator for determining the adipocyte lineage fate choices of stem cells. Stem Cells 32:1323-36.	LEAK OXPHOS	N NS	Permeabilized cells	Mouse	Other cell lines
Suchadolskiene 2014 BMC Neurosci	2014	Suchadolskiene O, Pranskunas A, Baliutyte G, Veikutis V, Dambrauskas Z, Vaitkaitis D, Borutaite V (2014) Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine. BMC Neurosci 15:2.	LEAK OXPHOS	N S	Isolated mitochondria	Pig	Nervous system
Cordero-Reyes 2014 J Mol Cell Cardiol	2014	Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ (2014) Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol 68:98-105.	LEAK OXPHOS ET	N S ROX	Isolated mitochondria	Human	Heart
Hasenour 2014 J Biol Chem	2014	Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9.	LEAK OXPHOS ET	N ROX	Isolated mitochondria	Mouse	Liver
Gnaiger 2014 MitoPathways	2014	Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4^th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp. — see 5^th edition: Gnaiger 2020 BEC MitoPathways.	LEAK ROUTINE OXPHOS ET	F N S Gp CIV NS ROX	Permeabilized cells Permeabilized tissue Homogenate Isolated mitochondria Intact cells	Human Mouse	Heart Skeletal muscle Fibroblast
Zachariah 2014 Diabetes	2014	Zachariah Tom R, Garcia-Roves PM, Sjögren RJ, Jiang LQ, Holmström MH, Deshmukh AS, Vieira E, Chibalin AV, Björnholm M, Zierath JR (2014) Effects of AMPK activation on insulin sensitivity and metabolism in leptin-deficient ob/ob mice. Diabetes 63:1560-71.	LEAK OXPHOS ET	N NS	Permeabilized tissue	Mouse	Skeletal muscle
Kemppainen 2014 Hum Mol Genet	2014	Kemppainen KK, Rinne J, Sriram A, Lakanmaa M, Zeb A, Tuomela T, Popplestone A, Singh S, Sanz A, Rustin P, Jacobs HT (2014) Expression of alternative oxidase in Drosophila ameliorates diverse phenotypes due to cytochrome oxidase deficiency. Hum Mol Genet 23:2078-93.		N CIV	Homogenate	Drosophila
Den Hollander 2014 Toxicol Sci	2014	den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31.	LEAK OXPHOS ET	N S NS ROX	Homogenate	Mouse	Nervous system
Vigueira 2014 Cell Rep	2014	Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN (2014) Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Rep 7:2042-53.	ET	N S	Isolated mitochondria	Mouse	Heart Kidney
Casanova 2014 J Nutr Biochem	2014	Casanova E, Baselga-Escudero L, Ribas-Latre A, Cedó L, Arola-Arnal A, Pinent M, Bladé C, Arola L, Salvadó MJ (2014) Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats. J Nutr Biochem 25:1003–10.	LEAK OXPHOS ET	F N S NS	Isolated mitochondria	Rat	Skeletal muscle
Chicco 2014 J Exp Biol	2014	Chicco AJ, Le CH, Schlater AE, Nguyen AD, Kaye SD, Beals JW, Scalzo RL, Bell C, Gnaiger E, Costa DP, Crocker DE, Kanatous SB (2014) High fatty acid oxidation capacity and phosphorylation control despite elevated leak and reduced respiratory capacity in northern elephant seal muscle mitochondria. J Exp Biol 217:2947-55.	LEAK OXPHOS ET	F N S NS	Permeabilized tissue	Human Other mammals	Skeletal muscle
Forkink 2014 Biochim Biophys Acta	2014	Forkink M, Manjeri GR, Liemburg-Apers DC, Nibbeling E, Blanchard M, Wojtala A, Smeitink JA, Wieckowski MR, Willems PH, Koopman WJ (2014) Mitochondrial hyperpolarization during chronic Complex I inhibition is sustained by low activity of Complex II, III, IV and V. Biochim Biophys Acta 1837:1247-56.	LEAK OXPHOS	N S CIV NS ROX	Permeabilized cells	Human	HEK
Cavalcanti-de-Albuquerque 2014 J Appl Physiol	2014	Cavalcanti-de-Albuquerque JP, Salvador IC, Martins EL, Jardim-Messeder D, Werneck-de-Castro JP, Galina A, Carvalho DP (2014) Role of estrogen on skeletal muscle mitochondrial function in ovariectomized rats: a time course study in different fiber types. J Appl Physiol 116:779-89.	LEAK OXPHOS	F N Gp NS ROX	Permeabilized tissue	Rat	Skeletal muscle
Correa 2014 Crit Care Med	2014	Corrêa TD, Jeger V, Pereira AJ, Takala J, Djafarzadeh S, Jakob SM (2014) Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Crit Care Med 42:e550-9.	LEAK OXPHOS	N S CIV NS	Permeabilized tissue Isolated mitochondria	Pig	Heart Liver Kidney
Chausse 2014 Endocrinology	2014	Chausse B, Solon C, Caldeira da Silva CC, Masselli Dos Reis IG, Manchado-Gobatto FB, Gobatto CA, Velloso LA, Kowaltowski AJ (2014) Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating. Endocrinology 9:e97673.	LEAK OXPHOS	N	Homogenate Isolated mitochondria	Rat	Skeletal muscle
Jimenez-Aranda 2014 J Pineal Res	2014	Jimenéz-Aranda A, Fernández-Vázquez G, Serrano MM, Reiter RJ, Agil A (2014) Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats. J Pineal Res 57:103-9.	LEAK OXPHOS	N S	Isolated mitochondria	Rat	Fat
Piel 2014 Acta Physiol (Oxf)	2014	Piel S, Ehinger JK, Elmér E, Hansson Magnus J (2014) Metformin induces lactate production in peripheral blood mononuclear cells and platelets through specific mitochondrial Complex I inhibition. Acta Physiol (Oxf) 213:171-80.	LEAK ROUTINE OXPHOS ET	N S CIV NS ROX	Permeabilized cells Intact cells	Human	Blood cells Other cell lines Platelet
Jackson 2014 J Med Genet	2014	Jackson CB, Nuoffer JM, Hahn D, Prokisch H, Haberberger B, Gautsch M, Häberli A, Gallati S, Schaller A (2014) Mutations in SDHD lead to autosomal recessive encephalomyopathy and isolated mitochondrial Complex II deficiency. J Med Genet 51:170-5.	OXPHOS	N S	Permeabilized cells	Human	Fibroblast
Garratt 2014 Proc Natl Acad Sci U S A	2014	Garratt M, Pichaud N, Glaros EN, Kee AJ, Brooks RC (2014) Superoxide dismutase deficiency impairs olfactory sexual signaling and alters bioenergetic function in mice. Proc Natl Acad Sci U S A 111:8119-24.	LEAK OXPHOS ET	F N S CIV NS ROX	Permeabilized tissue	Mouse	Liver
Kukat 2014 PLoS Genet	2014	Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A (2014) Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity. https://doi.org/10.1371/journal.pgen.1004385	LEAK OXPHOS ET	F N S NS ROX	Isolated mitochondria	Mouse	Heart
Sjoevall 2014 PLoS One	2014	Sjövall F, Morota S, Asander Frostner E, Hansson Magnus J, Elmer E (2014) Cytokine and nitric oxide levels in patients with sepsis - temporal evolvement and relation to platelet mitochondrial respiratory function. PLoS One 9:e97673.	LEAK OXPHOS ET	N S CIV NS ROX	Permeabilized cells	Human	Blood cells Platelet
Yano 2014 Nature Neurosci	2014	Yano H, Baranov SV, Baranova OV, Kim J, Pan Y, Yablonska S, Carlisle DL, Ferrante RJ, Kim AH, Friedlander RM (2014) Inhibition of mitochondrial protein import by mutant huntingtin. Nature Neurosci 17:822-31.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Nervous system
Ost 2014 PLoS One	2014	Ost M, Werner F, Dokas J, Klaus S, Voigt A (2014) Activation of AMPKa2 is not crucial for mitochondrial uncoupling-induced metabolic effects but required to maintain skeletal muscle integrity. PLoS One 14:e94689.	LEAK OXPHOS ET	F N NS	Permeabilized tissue	Mouse	Skeletal muscle
Van Bergen 2014 Mitochondrion	2014	Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33.	LEAK ROUTINE OXPHOS ET	N S NS	Permeabilized cells Isolated mitochondria Intact cells	Human Mouse	Nervous system Blood cells
Klepinin 2014 J Bioenerg Biomembr	2014	Klepinin A, Chekulayev V, Timohhina N, Shevchuk I, Tepp K, Kaldma A, Koit A, Saks V, Kaambre T (2014) Comparative analysis of some aspects of mitochondrial metabolism in differentiated and undifferentiated neuroblastoma cells. J Bioenerg Biomembr 46:17-31.	LEAK OXPHOS	N S CIV NS	Permeabilized cells	Mouse	Heart Other cell lines
Anmann 2014 Biochim Biophys Acta	2014	Anmann T, Varikmaa M, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Saks V, Kaambre T (2014) Formation of highly organized intracellular structure and energy metabolism in cardiac muscle cells during postnatal development of rat heart. Biochim Biophys Acta 1837:1350-61.	LEAK OXPHOS	N S	Permeabilized tissue	Rat	Heart
Larsen 2014 Anal Biochem	2014	Larsen S, Kraunsøe R, Gram M, Gnaiger E, Helge JW, Dela F (2014) The best approach: homogenization or manual permeabilization of human skeletal muscle fibers for respirometry? Anal Biochem 446:64-8.	LEAK OXPHOS ET	N NS	Permeabilized tissue Homogenate	Human Mouse	Skeletal muscle
Neves 2014 J Nutr Biochem	2014	Neves FA, Cortez E, Bernardoa AF, Mattos ABM, Vieira AK, Malafaia TO, Thole AA, Rodrigues-Cunha ACS, Garcia-Souza EP, Sichieri R, Moura AS (2014) Heart energy metabolism impairment in Western-diet induced obese mice. J Nutr Biochem 25:50-57.	LEAK OXPHOS	N NS ROX	Permeabilized tissue	Mouse	Heart
Ryu 2014 Cell Metab	2014	Ryu D, Jo YS, Lo Sasso G, Stein S, Zhang H, Perino A, Lee JU, Zeviani M, Romand R, Hottiger MO, Schoonjans K, Auwerx J (2014) A SIRT7-dependent acetylation switch of GABPβ1 controls mitochondrial function. Cell Metab 20:856-69.	LEAK OXPHOS	N S CIV NS Other combinations ROX	Homogenate	Mouse	Heart Nervous system Liver Lung;gill
Felser 2014 Toxicology I	2014	Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, Krähenbühl S (2014) Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. Toxicology 323:1-9.	LEAK OXPHOS	N S	Isolated mitochondria	Mouse	Liver
Divakaruni 2014 Curr Protoc Toxicol	2014	Divakaruni AS, Rogers GW, Murphy AN (2014) Measuring mitochondrial function in permeabilized cells using the Seahorse XF Analyzer or a clark-type oxygen electrode. Curr Protoc Toxicol 60:25.2.1-25.2.16.	LEAK OXPHOS ET	F N S Gp CIV ROX	Permeabilized cells	Mouse	Skeletal muscle Other cell lines
De Palma 2014 Skelet Muscle	2014	De Palma C, Morisi F, Pambianco S, Assi E, Touvier T, Russo S, Perrotta C, Romanello V, Carnio S, Cappello V, Pellegrino P, Moscheni C, Bassi MT, Sandri M, Cervia D, Clementi E (2014) Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation. Skelet Muscle 4:22.	LEAK OXPHOS ET	N S CIV NS	Permeabilized tissue Isolated mitochondria	Mouse	Skeletal muscle
Kamath 2014 J Biol Chem	2014	Kamath VG, Hsiung CH, Lizenby ZJ, McKee EE (2014) Heart mitochondrial TTP synthesis and the compartmentalization of TMP. J Biol Chem 290:2034-41.	LEAK OXPHOS	N	Isolated mitochondria	Rat	Heart
Cour 2014 J Cardiovasc Pharmacol Ther	2014	Cour M, Jahandiez V, Loufouat J, Ovize M, Argaud L (2014) Minor changes in core temperature prior to cardiac arrest influence outcomes: an experimental study. J Cardiovasc Pharmacol Ther pii:1074248414562911. 20:407-13.	LEAK OXPHOS	N	Isolated mitochondria	Rabbit	Heart Nervous system
Schiffer 2014 FASEB J	2014	Schiffer TA, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2014) Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans. FASEB J 28:4303-11.	LEAK OXPHOS ET	N S	Isolated mitochondria	Human	Skeletal muscle
Felser 2014 Toxicology II	2014	Felser A, Lindinger PW, Schnell D, Kratschmar DV, Odermatt A, Mies S, Jenö P, Krähenbühl S (2014) Hepatocellular toxicity of benzbromarone: effects on mitochondrial function and structure. Toxicology 324:136-46.	LEAK ROUTINE OXPHOS ET	N S ROX	Intact cells	Human	Liver Other cell lines
Valenti 2014 Anal Biochem	2014	Valenti D, de Bari L, De Filippis B, Ricceri L, Vacca RA (2014) Preservation of mitochondrial functional integrity in mitochondria isolated from small cryopreserved mouse brain areas. Anal Biochem 444:25-31.	OXPHOS ET	N S ROX	Isolated mitochondria	Mouse	Nervous system
Tretter 2014 Free Radic Biol Med	2014	Tretter L, Horvath G, Hölgyesi A, Essek F, Adam-Vizi V (2014) Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria. Free Radic Biol Med 77:317-30.	LEAK OXPHOS	N S Gp	Isolated mitochondria	Guinea pig	Nervous system
Frederick 2014 J Biol Chem	2014	Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA (2014) Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.. J Biol Chem. 290:1546-58.	LEAK OXPHOS	F N S ROX	Isolated mitochondria	Mouse	Skeletal muscle
Dogan 2014 Cell Metab	2014	Dogan SA, Pujol C, Maiti P, Kukat A, Wang S, Hermans S, Senft K, Wibom R, Rugarli EI, Trifunovic A (2014) Tissue-specific loss of DARS2 activates stress responses independently of respiratory chain deficiency in the heart. Cell Metab 19:458-69.	LEAK OXPHOS ET	N S	Permeabilized tissue Isolated mitochondria	Mouse	Heart Skeletal muscle Liver
Shama 2014 Funct Ecol	2014	Shama LNS, Strobel A, Mark FC, Wegner KM (2014) Transgenerational plasticity in marine sticklebacks: maternal effects mediate impacts of a warming ocean. Funct Ecol 28:1482–93.	LEAK OXPHOS ET	N ROX	Permeabilized tissue	Fishes	Heart
Fletcher 2014 Med Sci Sports Exerc	2014	Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.	LEAK OXPHOS ET	N S NS	Isolated mitochondria	Rat	Liver
Kivelae 2014 EMBO Mol Med	2014	Kivelä R, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21.	LEAK OXPHOS ET	F N S NS	Homogenate	Rat	Heart
Kucera 2014 Oxid Med Cell Longev	2014	Kučera O, Endlicher R, Roušar T, Lotková H, Garnol T, Drahota Z, Cervinková Z (2014) The effect of tert-butyl hydroperoxide-induced oxidative stress on lean and steatotic rat hepatocytes in vitro. Oxid Med Cell Longev 2014:752506.	LEAK OXPHOS	N S	Permeabilized cells	Rat	Liver Other cell lines
Broeker 2014 Thesis	2014	Broeker C (2014) Mitochondriopathien als Ursache des renalen Fanconi-Syndroms. Dissertation 85pp.	LEAK OXPHOS ET	N CIV NS ROX	Permeabilized cells	Pig	Kidney Other cell lines
Mourier 2014 Hum Mol Genet	2014	Mourier A, Ruzzenente B, Brandt T, Kühlbrandt W, Larsson NG (2014) Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet 23:2580-92.	LEAK OXPHOS ET	N S	Isolated mitochondria	Mouse	Heart
Pulliam 2014 Biochem J	2014	Pulliam DA, Deepa SS, Liu Y, Hill S, Lin AL, Bhattacharya A, Shi Y, Sloane L, Viscomi C, Zeviani M, Van Remmen H (2014) Complex IV-deficient Surf1(-/-) mice initiate mitochondrial stress responses. Biochem J 462:359-71.	LEAK OXPHOS	N ROX	Isolated mitochondria	Mouse	Heart Skeletal muscle
Cahova 2014 Appl Physiol Nutr Metab	2014	Cahova M, Chrastina P, Hansikova H, Drahota Z, Trnovska J, Skop V, Spacilova J, Malinska HOliyarnyk O, Papackova Z, Palenickova E,Kazdova L (2014) Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. Appl Physiol Nutr Metab 40:280-91.	OXPHOS	F N S	Isolated mitochondria	Rat	Liver
Bleier 2014 Free Radic Biol Med	2014	Bleier L, Wittig I, Heide H, Steger M, Brandt U, Droese S4 (2014) Generator-specific targets of mitochondrial reactive oxygen species. Free Radic Biol Med 78:1-10.	OXPHOS	N S ROX	Isolated mitochondria	Rat	Heart
Nunez-Figueredo 2014 Brain Res Bull	2014	Nunez-Figueredo Y, Pardo-Andreu GL, Ramirez-Sanchez J, Delgado-Hernandez R, Ochoa-Rodriguez E, Verdecia-Reyes Y, Naal Z, Muller AP, Portela LV, Souza DO (2014) Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca²⁺-induced mitochondrial impairment. Brain Res Bull 109:68-76.	ET	N S	Isolated mitochondria	Rat	Nervous system
Power 2014 Physiol Rep	2014	Power A, Pearson N, Pham T, Cheung C, Phillips A, Hickey A (2014) Uncoupling of oxidative phosphorylation and ATP synthase reversal within the hyperthermic heart. Physiol Rep pii:e12138.	LEAK OXPHOS ET	N NS	Isolated mitochondria	Rat	Heart
Van Bree 2014 PhD Thesis	2014	van Bree B (2014) Mitochondria, lipotoxicity and skeletal muscle metabolism: implications for type 2 diabetes mellitus. PhD Thesis 1-150.	LEAK OXPHOS ET	F N	Isolated mitochondria	Mouse	Skeletal muscle

Semantic search

Query log