Name | Jezek Jan, Dr. |
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Institution | Institute of Physiology, Lab. No. 75
Academy of Sciences of the Czech Rep. |
Address | Videnska 1083, 14220 |
City | Prague |
State/Province | |
Country | Czech Republic |
Weblink | |
O2k-Network Lab | CZ Prague Jezek P |
Labels:
Field of research: Basic
Publications
Published | Reference | |
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Plecita-Hlavata 2020 Antioxid Redox Signal | 2020 | Plecitá-Hlavatá L, Engstová H, Holendová B, Tauber J, Špaček T, Petrásková L, Křen V, Špačková J, Gotvaldová K, Ježek J, Dlasková A, Smolková K, Ježek P (2020) Mitochondrial superoxide production decreases on glucose-stimulated insulin secretion in pancreatic β cells due to decreasing mitochondrial matrix NADH/NAD+ ratio. Antioxid Redox Signal 33:789-815. |
Jezek 2017 Biochim Biophys Acta | 2017 | Ježek J, Engstová H, Ježek P (2017) Antioxidant mechanism of mitochondria-targeted plastoquinone SkQ1 is suppressed in aglycemic HepG2 cells dependent on oxidative phosphorylation. Biochim Biophys Acta 1858:750-62. |
Jezek 2015 Antioxid Redox Signal | 2015 | Ježek J, Dlasková A, Zelenka J, Jabůrek M, Ježek P (2015) H2O2-activated mitochondrial phospholipase iPLA2γ prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GPR40, and regulates insulin secretion in pancreatic β-cells. Antioxid Redox Signal 23:958-72. |
Plecita-Hlavata 2015 J Bioenerg Biomembr | 2015 | Plecitá-Hlavatá L, Ježek J, Ježek P (2015) Aglycemia keeps mitochondrial oxidative phosphorylation under hypoxic conditions in HepG2 cells. J Bioenerg Biomembr 47(6):467-76. |
Jaburek 2013 Int J Biochem Cell Biol | 2013 | Jabůrek M, Ježek J, Zelenka J, Ježek P (2013) Antioxidant activity by a synergy of redox-sensitive mitochondrial phospholipase A2 and uncoupling protein-2 in lung and spleen. Int J Biochem Cell Biol 45:816-25. |
Jezek 2010 Physiol Res | 2010 | Ježek J, Jabůrek M, Zelenka J, Ježek P (2010) Mitochondrial phospholipase A2 activated by reactive oxygen species in heart mitochondria induces mild uncoupling. Physiol Res 59:737-47. |
Plecita-Hlavata 2009 Int J Biochem Cell Biol | 2009 | Plecita-Hlavata L, Jezek J, Jezek P (2009) Pro-oxidant mitochondrial matrix-targeted ubiquinone MitoQ10 acts as anti-oxidant at retarded electron transport or proton pumping within Complex I. Int J Biochem Cell Biol 41:1697-707. |
Dlaskova 2008 Int J Biochem Cell Biol | 2008 | Dlasková A, Hlavatá L, Jezek J, Jezek P (2008) Mitochondrial Complex I superoxide production is attenuated by uncoupling. Int J Biochem Cell Biol 40:2098-109. |
Abstracts
Published | Reference | |
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Jaburek 2014 Abstract MiP2014 | 2014 | The role of phospholipase A2γ in the regulation of mitochondrial uncoupling protein 2–dependent antioxidant function. |
Jezek 2013 Abstract MiP2013 | 2013 | Ježek P, Ježek J, Zelenka J, Dlasková A, Jabůrek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2γ. Mitochondr Physiol Network 18.08. |
Gabrielova 2011 Abstract IOC61 | 2011 | Gabrielova E, Jaburek M, Gazak R, Vostalova J, Jezek J, Kren V, Modriansky M (2011) Evaluation of an oxygen consumption in rat heart mitochondria treatment by polyphenol compounds. MiPNet16.01. |