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COST Action CA15203 (2016-2021): MitoEAGLE
Evolution-Age-Gender-Lifestyle-Environment: mitochondrial fitness mapping
Lopez Garcia Luis Carlos
MitoPedia topics: EAGLE
COST: Member
COST WG2: WG2
Name | López García Luis Carlos, Dr. |
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Institution | Biomedical Research Center,
University of Granada /PTS Granada, ES |
Address | Avenida del Conocimiento, s/n, 18016 |
City | Granada |
State/Province | |
Country | Spain |
luisca@ugr.es | |
Weblink | http://wpd.ugr.es/~luisca/ |
O2k-Network Lab |
Labels:
Publications
Published | Reference | |
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Hidalgo-Gutierrez 2021 Antioxidants (Basel) | 2021 | Hidalgo-Gutiérrez A, González-García P, Díaz-Casado ME, Barriocanal-Casado E, López-Herrador S, Quinzii CM, López LC (2021) Metabolic targets of coenzyme Q10 in mitochondria. Antioxidants (Basel) 10:520. https://doi.org/10.3390/antiox10040520 |
BEC 2020.1 doi10.26124bec2020-0001.v1 | 2020 | Gnaiger E et al ― MitoEAGLE Task Group (2020) Mitochondrial physiology. Bioenerg Commun 2020.1. https://doi.org/10.26124/bec:2020-0001.v1 |
Doerrier 2016 Mitochondrion | 2016 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Luna-Sánchez M, Fernández-Gil B, Escames G, López LC, Acuña-Castroviejo D (2016) Permeabilized myocardial fibers as model to detect mitochondrial dysfunction during sepsis and melatonin effects without disruption of mitochondrial network. Mitochondrion 27:56-63. |
Volt 2016 J Pineal Res | 2016 | Volt H, García JA, Doerrier C, Díaz-Casado ME, Guerra-Librero A, López LC, Escames G, Tresguerres JA, Acuña-Castroviejo D (2016) Same molecule but different expression: aging and sepsis trigger NLRP3 inflammasome activation, a target of melatonin. J Pineal Res 60:193-205. |
Garcia 2015 FASEB J | 2015 | García JA, Volt H, Venegas C, Doerrier C, Escames G, López LC, Acuña-Castroviejo D (2015) Disruption of the NF-κB/NLRP3 connection by melatonin requires retinoid-related orphan receptor-α and blocks the septic response in mice. FASEB J 29:3863-75. |
García-Corzo 2015 Biochim Biophys Acta | 2015 | García-Corzo L, Luna-Sánchez M, Doerrier C, Ortiz F, Escames G, Acuña-Castroviejo D, López LC (2015) Ubiquinol-10 ameliorates mitochondrial encephalopathy associated with CoQ deficiency. Biochim Biophys Acta 1842:893-901. |
Ortiz 2015 J Pineal Res | 2015 | Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49. |
Acuña-Castroviejo 2014 Cell Mol Life Sci | 2014 | Acuña-Castroviejo D, Escames G, Venegas C, Díaz-Casado ME, Lima-Cabello E, López LC, Rosales-Corral S, Tan DX, Reiter RJ (2014) Extrapineal melatonin: sources, regulation, and potential functions. Cell Mol Life Sci 71:2997-25. |
Doerrier 2014 Life Sci | 2014 | Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65. |
Ortiz 2014 J Pineal Res | 2014 | Ortiz F, García JA, Acuña-Castroviejo D, Doerrier C, López A, Venegas C, Volt H, Luna-Sánchez M, López LC, Escames G (2014) The beneficial effects of melatonin against heart mitochondrial impairment during sepsis: inhibition of iNOS and preservation of nNOS. J Pineal Res 56:71-81. |
Garcia-Corzo 2013 Hum Mol Genet | 2013 | García-Corzo L, Luna-Sánchez M, Doerrier C, García JA, Guarás A, Acín-Pérez R, Bullejos-Peregrín J, López A, Escames G, Enríquez JA, Acuña-Castroviejo D, López LC (2013) Dysfunctional Coq9 protein causes predominant encephalomyopathy associated with CoQ deficiency. Hum Mol Genet 22:1233-48. |
Escames 2013 Horm Mol Biol Clin Investig | 2013 | Escames G, Diaz-Casado ME, Doerrier C, Luna-Sanchez M, Lopez LC, Acuna-Castroviejo D (2013) Early gender differences in the redox status of the brain mitochondria with age: effects of melatonin therapy. Horm Mol Biol Clin Investig 16(2):91-100. |
Acuña-Castroviejo 2012 Age (Dordr) | 2012 | Acuña-Castroviejo D, Carretero M, Doerrier C, López LC, García-Corzo L, Tresguerres JA, Escames G (2012) Melatonin protects lung mitochondria from aging. Age (Dordr) 34(3):681-92. |
Acuña-Castroviejo 2011 Curr Top Med Chem | 2011 | Acuña-Castroviejo D; López LC; Escames G; López A; García JA; Reiter RJ (2011) Melatonin-mitochondria interplay in health and disease. Curr Top Med Chem 11:221-240. |
Lopez 2009 J Pineal Res | 2009 | López A, García JA, Escames G, Venegas C, Ortiz F, López LC, Acuña-Castroviejo D (2009) Melatonin protects the mitochondria from oxidative damage reducing oxygen consumption, membrane potential, and superoxide anion production. J Pineal Res 46:188-98. |
Abstracts
Published | Reference | |
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Barriocanal-Casado 2015 Abstract MiP2015 | 2015 | Targeting nutrient signaling pathways for the treatment of mitochondrial diseases. |
Hidalgo-Gutierrez 2015 Abstract MiP2015 | 2015 | Strategies to enhance the endogenous biosynthesis of Coenzyme Q. |
Lopez 2015 Abstract MiP2015 | 2015 | Unraveling the causes of the clinical heterogeneity of coenzyme Q10 deficiency due to different molecular defects in Coq9 gene. |
Doerrier 2014 Abstract SECF | 2014 | Evaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice. |
Luna-Sánchez 2014 Abstract SECF | 2014 | Mitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment. |
Garcia 2014 Abstract SECF | 2014 | Melatonin disrupts the NF-κB/NLRP3 connection in sepsis through RORα receptor. |
Volt 2014 Abstract The 2014 Ageing Summit | 2014 | Effects of melatonin on the age-dependent dysregulation of the Nf-Kb/Nlrp3 activation during sepsis. |
Ortiz 2013 Abstract SEOR | 2013 | Molecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin. |
Luna-Sánchez 2012 Abstract MiPsummer School Cambridge | 2012 | CoQ deficiency: molecular and phathophysiological consequences. |
Luna-Sánchez 2012 Abstract FEPS&SECF | 2012 | CoQ deficiency: Molecular and pathophysiological consequences. |
Escames 2012 Abstract ESTRO | 2012 | Beneficial effects of topical melatonin against mitochondrial damage during radiotherapy-induced mucositis. |
Garcia-Corzo 2011 Abstract Euromit 8 | 2011 | Generation of a mouse model of Coenzyme Q deficiency. |
Escames 2011 Abstract FASEB Summer Research Conference | 2011 | Melatonin regulates the proliferation and differentation of the mice subventricular neural stem cells. Role of mitochondria. |