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- |authors=Rutkai I, Katakam P, Busija D ...Sprague Dawley rats. The ovariectomized rats were treated with either a 21 d release, 0.5 mg of 17 -estradiol pellet (OVX+E) or placebo (OVX). The OC4 KB (524 words) - 15:53, 13 November 2017