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  • |Title=[http://www.liebertpub.com/hum Human Gene Therapy]
    70 bytes (10 words) - 17:42, 22 March 2017
  • ...a S, Yokota T, Kinugawa S, Harashima H, Yamada Y (2021) Validation of gene therapy for mutant mitochondria by delivering mitochondrial RNA using a MITO-porter ...rapeutic nucleic acids represents a viable strategy for mitochondrial gene therapy.
    2 KB (322 words) - 16:36, 8 March 2021
  • ...phy induced by pressure-overload via improving mitochondrial function. Hum Gene Ther 31:1178-89. |journal=Hum Gene Ther
    2 KB (315 words) - 13:35, 20 October 2021
  • ...V genetic mutations in yeast will be amenable to AOX gene therapy. As many human genes are orthologous to those found in yeast, our invention represents an
    2 KB (337 words) - 14:13, 20 October 2017
  • ...augments mitochondrial physiology in a Parkinson's disease cell model. Hum Gene Ther 20:897-907. |journal=Hum Gene Ther
    3 KB (405 words) - 14:52, 13 November 2017
  • ...Leber’s hereditary optic neuropathy and T8993G Leigh’s syndrome cells. Hum Gene Ther 23:647-57. |journal=Hum Gene Ther
    2 KB (292 words) - 03:51, 23 November 2021
  • ...ed hepatic steatosis in mice and highlights potential lipid biomarkers for human NAFLD. FASEB J 34:11816-37. ...isease. To sum up, here we show for the first time that liver hCPT1AM gene therapy in a mouse model of established obesity, diabetes, and NAFLD can reduce HFD
    3 KB (396 words) - 16:06, 6 December 2021
  • ...models for proof-of-principle studies toward conducting mitochondrial gene therapy in the future. We introduced healthy mtDNA first into the cytoplasmic hybri |organism=Human
    5 KB (708 words) - 15:23, 9 November 2016
  • ...Lempicki RA, Dalakas MC, Kovacs JA (2012) HIV infection and antiretroviral therapy have divergent effects on mitochondria in adipose tissue. J Infect Dis 205: ...: Although human immunodeficiency virus (HIV) infection and antiretroviral therapy (ART) affect mitochondrial DNA (mtDNA) content and function, comprehensive
    2 KB (325 words) - 15:13, 23 February 2020
  • ...lic effects of the HIV protease inhibitor – saquinavir in differentiating human preadipocytes. Pharmacol Rep 65:937-50. ...S7) culture. Results: SQV in concentrations observed during antiretroviral therapy (ART) significantly decreased mitochondrial membrane potential (MMP), oxyge
    2 KB (262 words) - 21:08, 18 March 2018
  • |title=Hyperlactatemia and mtDNA polymerase - gene mutations in HIV infected Zulu patients on stavudine-based HAART. ...u patients exposed to NRTI stavudine or zidovudine in their antiretroviral therapy. One hundred and sixteen patients from Edendale Hospital consented to be in
    4 KB (500 words) - 10:25, 9 March 2015
  • ...K, Augsburger B, Steliou K, Trounce IA, Irwin MH (2013) Murine modeling of human mitochondrial disease pathogenesis. Mitochondr Physiol Network 18.08. ...veloped or are currently characterizing transmitochondrial mouse models of human disease including models for Parkinson’s disease and Complex I assembly,
    3 KB (382 words) - 17:20, 27 March 2018
  • ...ub>β<sub>7</sub> integrin in adults. The severity and therapeutic response gene signatures were in turn associated with shifts in microbes previously impli |organism=Human
    3 KB (391 words) - 11:25, 8 August 2019
  • ...chagasic myocardium. Inhibition of mitochondrial PARP1/PAR offers a novel therapy in preserving the mitochondrial and LV function in chronic Chagas disease.
    3 KB (372 words) - 11:35, 27 July 2018
  • ...of presence within mammalian systems has led to its potential use in gene therapy to treat Alzheimers and Parkinsons diseases which are characterised by mito
    2 KB (330 words) - 12:18, 7 March 2020
  • ...c methods to detect oxaliplatin-induced cardiotoxicity early on as well as therapy to compensate for the energy deficit in the heart to prevent heart damage.
    2 KB (332 words) - 16:19, 13 October 2023
  • ...onal transport in Parkinson's disease cybrid neurites is restored by light therapy. Mol Neurodegener 4:26. ...ess this hypothesis, we measured the velocity of mitochondrial movement in human transmitochondrial cybrid "cytoplasmic hybrid" neuronal cells bearing mitoc
    3 KB (465 words) - 15:40, 20 March 2015
  • ...etastatic prostate cancer cells could yield a novel target for anti-cancer therapy and has the potential to be used for imaging-based diagnostics to detect no ...metastatic prostate cancer DU145 cells, Human primary prostate cells PrEC, Human ovarian cancer cells SKOV-3, Rat aortic endothelial cells
    3 KB (353 words) - 16:11, 20 April 2021
  • ...tisfactory therapy. The disease is caused by loss of function of the ABCD1 gene, a peroxisomal ATP-binding cassette transporter, resulting in the accumulat |organism=Human
    2 KB (223 words) - 11:24, 9 March 2015
  • |title=Alternative respiratory chain enzymes in research and therapy. ...the alternative oxidase (AOX) from the tunicate ''Ciona intestinalis'' in human cells, mouse and ''Drosophila'', as well as expression of the single-subuni
    3 KB (438 words) - 10:12, 9 November 2016

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