Cookies help us deliver our services. By using our services, you agree to our use of cookies. More information

Carnitine palmitoyltransferase II

From Bioblast
Revision as of 16:45, 13 April 2023 by Cardoso Luiza (talk | contribs)
(diff) ← Older revision | Latest revision (diff) | Newer revision β†’ (diff)

high-resolution terminology - matching measurements at high-resolution

Carnitine palmitoyltransferase II


Carnitine palmitoyltransferase II (CPT-II, also known as carnitine acyltransferase II) is part of the carnitine shuttle which is responsible for the mitochondrial transport of long-chain fatty acids. CPT-II is located on the inner side of the mtIM and converts the acylcarnitines (produced in the reaction catalyzed by carnitine palmitoyltransferase I) to carnitine and acyl-CoAs, which undergo ß-oxidation in the mitochondrial matrix. Free carnitines are transported out of the mitochondrial matrix in exchange for acyl-carnitines via an integral mtIM protein carnitine-acylcarnitine translocase (CACT). Short- and medium-chain fatty acids do not require the carnitine shuttle for mitochondrial transport.

Abbreviation: CPT-II

MitoPedia topics: Enzyme