Chavanelle 2015 Fatty Acid Oxidation O2k-Network Discussion Forum
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| Chavanelle 2015 Fatty Acid Oxidation O2k-Network Discussion Forum |
Link: O2k-Network Discussion Forum
Chavanelle V (2015)
Event: Fatty Acid Oxidation O2k-Network Discussion Forum
Fatty oxidation in permeabilised db/db mice muscle fibres, in Mir05 + Cr +37°C. We found that ADP-stimulated respiration in presence of 0,02mM of palmitoyl-carnitine (OXPHOS) is very close to the non-ADP-stimulated respiration (LEAK state) when working with these conditions. (Values around 14 to 20 (pmol/s/mg w.t.) for leak state and 15 to 24 (pmol/s/mg w.t.) for fatty acid triggered-OXPHOS). These data suggest either a very poor ability for this animal model to use palmitoyl-carnitine or a very high leak state (or both!)
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Palmitoylcarnitine
