Gutman 1972 FEBS Lett
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| Gutman M, Silman N (1972) Mutual inhibition between NADH oxidase and succinoxidase activities in respiring submitochondrial particles. FEBS Lett 26:207-10. doi: 10.1016/0014-5793(72)80574-x. |
Gutman M, Silman N (1972) FEBS Lett
Abstract: The dehydrogenases of the respiratory system can oxidize substrates at rates much higher than the respiration rate. When more than one substrate is oxidized, the rate of respiration is less than the sum of the rates of respiration on each substrate separately [ 1-4]. In such a case, not only are the dehydrogenases partially utilized, but they also inhibit each other. This type of mutual inhibition was postulated to operate at the junction of the flavoprotein and the CoQlo [5], but a detailed mechanism was not proposed.
• Bioblast editor: Gnaiger E
Labels: MiParea: Respiration
Preparation: SMP
Regulation: Flux control, Inhibitor, Q-junction effect
Pathway: N, S, NS
- ETPH, electron transport particle (membrane preparation)
