Jones 2017 Elsevier: Difference between revisions

Latest revision as of 16:01, 29 October 2023

Jones PM, Bennett MJ (2017) Chapter 4 - Disorders of mitochondrial fatty acid β-oxidation. Elsevier In: Garg U, Smith LD , eds. Biomarkers in inborn errors of metabolism. Clinical aspects and laboratory determination:87-101. https://doi.org/10.1016/C2014-0-03841-5

Abstract:

• Bioblast editor: Gnaiger E

Labels:

Pathway: F

@@ Line 7: / Line 7: @@
 |editor=Gnaiger E
 }}
-== Correction: FADH<sub>2</sub> and S-pathway ==
-::::* [[Complex II ambiguities]]
-:::: [[File:Jones, Bennett 2017 Chapter 4 CORRECTION.png|800px]]
-:::: A commonly found error on FADH<sub>2</sub> in the S-pathway requires correction. For clarification, see page 48 in [[Gnaiger_2020_BEC_MitoPathways |Gnaiger (2020)]]
-::::* Quote (p 48): "The  substrate  of  CII  is  succinate,  which  is  oxidized  forming  fumarate  while reducing flavin adenine dinucleotide FAD to FADH<sub>2</sub>, with further electron transfer to the quinone pool. Whereas reduced NADH is a substrate of Complex I linked to dehydrogenases of the TCA cycle and mt-matrix upstream of CI,  reduced  FADH<sub>2</sub> is a product of Complex II with downstream electron flow from CII to Q."
-:::::: Gnaiger E (2020) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 5th ed. Bioenerg Commun 2020.2. https://doi.org/10.26124/bec:2020-0002
 {{Labeling
-|pathways=F, S
+|pathways=F
 }}