Difference between revisions of "Loew 1963 Biochim Biophys Acta"
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{{Publication | {{Publication | ||
|title=Loew H, Vallin I (1963) Succinate-linked diphosphopyridine nucleotide reduction in submitochondrial particles. Biochim Biophys Acta 69: 361- | |title=Loew H, Vallin I (1963) Succinate-linked diphosphopyridine nucleotide reduction in submitochondrial particles. Biochim Biophys Acta 69:361-4. | ||
|info=[http://www.sciencedirect.com/science/journal/00063002/69 ScienceDirect] | |info=[http://www.sciencedirect.com/science/journal/00063002/69 ScienceDirect] | ||
|authors=Loew H, Vallin I | |authors=Loew H, Vallin I | ||
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# The effect of DPNH was marked only if added in a concentration equal to or exceeding that of DPN. | # The effect of DPNH was marked only if added in a concentration equal to or exceeding that of DPN. | ||
# Respiratory inhibitors acting in the flavin region of the respiratory chain blocked the reaction. | # Respiratory inhibitors acting in the flavin region of the respiratory chain blocked the reaction. | ||
|keywords=Succinate, DPN, ATP, Beef heart | |||
|keywords= | |||
}} | }} | ||
{{Labeling | {{Labeling | ||
|organism= | |organism=Bovines | ||
|tissues= | |tissues=Heart | ||
|preparations=Isolated | |preparations=Isolated mitochondria | ||
|enzymes=Complex II; | |enzymes=Complex II;succinate dehydrogenase | ||
|topics=ATP | |topics=ATP | ||
|additional=Made history | |additional=Made history | ||
}} | }} | ||
Latest revision as of 14:34, 24 November 2015
| Loew H, Vallin I (1963) Succinate-linked diphosphopyridine nucleotide reduction in submitochondrial particles. Biochim Biophys Acta 69:361-4. |
Loew H, Vallin I (1963) Biochim Biophys Acta
Abstract:
- The reduction of added DPN by succinate catalyzed by submitochondrial particles from beef heart has been studied.
- The reduction was endergonic and required specifically the addition of ATP.
- The reaction had a limited specificity for electron acceptors; six DPN analogues tested were reduced at the same rate or nearly the same rate, as was DPN. TPN was only reduced at a very slow rate.
- The rate of reduction was influenced by phosphate and ADP and their effects became pronounced if added together.
- The effect of DPNH was marked only if added in a concentration equal to or exceeding that of DPN.
- Respiratory inhibitors acting in the flavin region of the respiratory chain blocked the reaction.
• Keywords: Succinate, DPN, ATP, Beef heart
Labels:
Organism: Bovines
Tissue;cell: Heart
Preparation: Isolated mitochondria
Enzyme: Complex II;succinate dehydrogenase
Regulation: ATP
Made history
