Loew 1963 Biochim Biophys Acta
| Loew H, Vallin I (1963) Succinate-linked diphosphopyridine nucleotide reduction in submitochondrial particles. Biochim Biophys Acta 69: 361-364. |
Loew H, Vallin I (1963) Biochim Biophys Acta
Abstract:
- The reduction of added DPN by succinate catalyzed by submitochondrial particles from beef heart has been studied.
- The reduction was endergonic and required specifically the addition of ATP.
- The reaction had a limited specificity for electron acceptors; six DPN analogues tested were reduced at the same rate or nearly the same rate, as was DPN. TPN was only reduced at a very slow rate.
- The rate of reduction was influenced by phosphate and ADP and their effects became pronounced if added together.
- The effect of DPNH was marked only if added in a concentration equal to or exceeding that of DPN.
- Respiratory inhibitors acting in the flavin region of the respiratory chain blocked the reaction.
• Keywords: succinate, DPN, ATP
Labels:
Organism: Other Mammal"Other Mammal" is not in the list (Human, Pig, Mouse, Rat, Guinea pig, Bovines, Horse, Dog, Rabbit, Cat, ...) of allowed values for the "Mammal and model" property.
Tissue;cell: Cardiac muscle"Cardiac muscle" is not in the list (Heart, Skeletal muscle, Nervous system, Liver, Kidney, Lung;gill, Islet cell;pancreas;thymus, Endothelial;epithelial;mesothelial cell, Blood cells, Fat, ...) of allowed values for the "Tissue and cell" property.
Preparation: Isolated Mitochondria"Isolated Mitochondria" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property.
Enzyme: Complex II; Succinate Dehydrogenase"Complex II; Succinate Dehydrogenase" is not in the list (Adenine nucleotide translocase, Complex I, Complex II;succinate dehydrogenase, Complex III, Complex IV;cytochrome c oxidase, Complex V;ATP synthase, Inner mt-membrane transporter, Marker enzyme, Supercomplex, TCA cycle and matrix dehydrogenases, ...) of allowed values for the "Enzyme" property.
Regulation: ATP; ADP; AMP; PCr"ATP; ADP; AMP; PCr" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
Made history
