MiPMap: Difference between revisions
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The project '''Mitochondrial Physiology Map''' is initiated to create a list of mitochondrial properties in cell types, tissues and species. As part of MitoPedia, '''MiPMap''' will provide an ''information synthase'' for '''Comparative Mitochondrial Physiology'''. This project will require global input to establish a comprehensive database. | The project '''Mitochondrial Physiology Map''' is initiated to create a list of mitochondrial properties in cell types, tissues and species. As part of MitoPedia, '''MiPMap''' will provide an ''information synthase'' for '''Comparative Mitochondrial Physiology'''. This project will require global input to establish a comprehensive database. | ||
== MiPMap list of mitochondrial properties in organisms (species), and cell types and tissues == | |||
=== 1. Human and model organisms, and taxonomic groups === | |||
''Work in progress'' | ''Work in progress'' | ||
As a test case, O2k-Publications are listed according to organisms: | |||
:: >> [[O2k-Publications:_Specific_topics#Organisms|Organisms]] | |||
: For example, in this list you may find information on '''mouse''' cell lines and tissues, e.g. '''mouse kidney mitochondria''': | : For example, in this list you may find information on '''mouse''' cell lines and tissues, e.g. '''mouse kidney mitochondria''': | ||
:: * Is malic enzyme present? | :: * Is malic enzyme present? | ||
| Line 17: | Line 20: | ||
:: * Preparation of isolated mitochondria, permeabilized tissuem, homogenate. | :: * Preparation of isolated mitochondria, permeabilized tissuem, homogenate. | ||
:: * Which respiration medium is recommended? ->> Do not use media with K<sup>+</sup>, which inhibits kidney mitochondrial respiration. | :: * Which respiration medium is recommended? ->> Do not use media with K<sup>+</sup>, which inhibits kidney mitochondrial respiration. | ||
>> Is this | >> Is this a general issue for the organ, or is it in addition also a species issue? (according to [[Calzia E]] MiR05 works fine with kidney tissue from pig, but not in mouse). | ||
=== 2. Cell types and Tissues === | === 2. Cell types and Tissues === | ||
: Or you may find '''Skeletal muscle mitochondria''' | : Or you may find '''Skeletal muscle mitochondria''' studied across species: | ||
:: * Human | :: * '''Skeletal muscle''' - '''Human''' | ||
::: ->> [[Human_-_Skeletal_muscle]] | ::: ->> [[O2k-Publications: Human_-_Skeletal_muscle]] | ||
=== 3. Diseases === | |||
''Work in progress'' | ''Work in progress'' | ||
[[O2k-Publications:_Specific_topics#Medical_and_pharmacological_applications]] | |||
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Revision as of 12:16, 30 January 2013
- high-resolution terminology - matching measurements at high-resolution
MiPMap
Description
Mitochondrial Physiology Map - MiPMap
The project Mitochondrial Physiology Map is initiated to create a list of mitochondrial properties in cell types, tissues and species. As part of MitoPedia, MiPMap will provide an information synthase for Comparative Mitochondrial Physiology. This project will require global input to establish a comprehensive database.
MiPMap list of mitochondrial properties in organisms (species), and cell types and tissues
1. Human and model organisms, and taxonomic groups
Work in progress
As a test case, O2k-Publications are listed according to organisms:
- >> Organisms
- For example, in this list you may find information on mouse cell lines and tissues, e.g. mouse kidney mitochondria:
- * Is malic enzyme present?
- * Is the P/E<1.0 like in mouse brain but different from mouse skeletal muscle?
- * Which UCPs are present?
- * Preparation of isolated mitochondria, permeabilized tissuem, homogenate.
- * Which respiration medium is recommended? ->> Do not use media with K+, which inhibits kidney mitochondrial respiration.
>> Is this a general issue for the organ, or is it in addition also a species issue? (according to Calzia E MiR05 works fine with kidney tissue from pig, but not in mouse).
2. Cell types and Tissues
- Or you may find Skeletal muscle mitochondria studied across species:
- * Skeletal muscle - Human
3. Diseases
Work in progress
O2k-Publications:_Specific_topics#Medical_and_pharmacological_applications
Initiation
- Presented at Bioblast 2012.
- Focus for MiPconference on Comparative Mitochondrial Physiology.
References and notes
