MitoCom lectures

MitoCom Lectures

MitoCom Lectures: Introduction to mitochondrial respiratory physiology - Innsbruck, November 2011

An informal series of lectures will be held in November 2011 in the OROBOROS Office, Schöpfstr. 18, Innsbruck, as an introduction to mitochondrial respiratory physiology. The specific topics will be used primarily to explain the general underlying concepts. Lectures will be complemented by group discussions of relevant literature and experimental progress.

• 2011-Nov-03, 8:15 - 09:45

E. Gnaiger (Innsbruck): Approaching in vivo mitochondrial function: Coupling and substrate control of mitochondrial respiration in active and sedentary life styles. (Abstract 1; Abstract 2)

• 2011-Nov-08, 8:15 - 09:45

E. Gnaiger (Innsbruck): The Greenland expedition: Are mitochondria of traditional Inuit hunters (Northern haplotypes) more uncoupled for higher heat production? (Perspectives)

• 2011-Nov-10, 8:15 - 09:45

P. Jezek (Prague): Mitochondrial structure and function. (to be confirmed)

• 2011-Nov-15, 8:15 - 09:45

D. Pesta (Innsbruck): Endurance and strength training in sedentary controls and elite endurance athletes: Are trained mitochondria less coupled? (Abstract 1; Abstract 2)

E. Gnaiger (Innsbruck): Experimental validation of substrate-uncoupler-inhibitor titration protocols with NIH3T3 fibroblasts. (Abstract)

• 2011-Nov-17, 8:15 - 09:45

E. Gnaiger (Innsbruck): Mitochondrial respiratory capacity at maximum aerobic exercise: Are intracellular oxygen levels limiting? (Abstract and References)

• 2011-Nov-22, 8:15 - 09:45

E. Gnaiger (Innsbruck): From mouse to man, from muscle to brain. Comparative mitochondrial physiology. (Abstract 1; Abstract 2)

Informal registration

• Please, contact: katrin.stecher@oroboros.at
• Participants should make themselves familiar with fundamental mitochondrial pathways and respiratory states: MitoPathways.

Reading list

• Is mitochondrial respiratory function different in permeabilized fibres and isolated mitochondria?

Picard M, Taivassalo T, Ritchie D, Wright KJ, Thomas MM, Romestaing C, Hepple RT (2011) Mitochondrial structure and function are disrupted by standard isolation methods. PLoS One 6: 1-12.

• Mitochondrial efficiency

Larsen FJ, Schiffer TA, Borniquel S, Sahlin K, Ekblom B, Lundberg JO, Weitzberg E (2011) Dietary inorganic nitrate improves mitochondrial efficiency in humans. Cell Metab. 13: 149-159.