MitoKit-CII/Succinate-nv: Difference between revisions
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|abbr=S(p) | |abbr=S(p) | ||
|description='''NV118 (diacetoxymethyl succinate; Sp)''', is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing succinate in the intracellular space. | |description='''NV118 (diacetoxymethyl succinate; Sp)''', is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing succinate in the intracellular space. | ||
|info=[[ | |info=[[MitoKit-CII]], [[MitoFit-CII|MitoPedia:MitoFit-CII]], [[Ehinger 2016 Nat Commun]] | ||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Medium | |mitopedia topic=Medium | ||
}} | }} | ||
* For preparation of MitoFit-CII, see [[ | * For preparation of MitoFit-CII, see [[MitoKit-CII]]. |
Revision as of 11:33, 25 March 2019
Description
NV118 (diacetoxymethyl succinate; Sp), is a plasma membrane-permeable (p) prodrug that diffuses across the plasma membrane. Cleavage of diacetoxymethyl residues is mediated by intracellular esterases, thus releasing succinate in the intracellular space.
Abbreviation: S(p)
Reference: MitoKit-CII, MitoPedia:MitoFit-CII, Ehinger 2016 Nat Commun
MitoPedia topics:
Media for respirometry
- For preparation of MitoFit-CII, see MitoKit-CII.