Difference between revisions of "MitoKit-CII MitoPedia"
From Bioblast
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{{MitoPedia | {{MitoPedia | ||
|abbr=MitoKit-CII | |abbr=MitoKit-CII | ||
|description='''Cell permeable prodrugs''', composed of [[ | |description='''Cell permeable prodrugs''', composed of [[MitoKit-CII/Succinate-nv]] and [[MitoKit-CII/Malonate-nv]], stimulates (Snv) or inhibits (Mnanv) mitochondrial respiration in CI-deficient human blood cells, fibroblasts and heart fibres, acting on Complex II of the electron transfer system. | ||
|info=[[MitoKit-CII]], [[Ehinger 2016 Nat Commun]] | |info=[[MitoKit-CII]], [[Ehinger 2016 Nat Commun]] | ||
}} | }} | ||
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::::* | ::::* [[MitoKit-CII/Succinate-nv]]: 100 mM stock solution | ||
::::* | ::::* [[MitoKit-CII/Malonate-nv]]: 10 mM stock solution | ||
== SUITbrowser question: Permeable succinate/malonate == | == SUITbrowser question: Permeable succinate/malonate == | ||
Work in progress | Work in progress | ||
Revision as of 17:16, 3 June 2019
- high-resolution terminology - matching measurements at high-resolution
MitoKit-CII MitoPedia
Description
Cell permeable prodrugs, composed of MitoKit-CII/Succinate-nv and MitoKit-CII/Malonate-nv, stimulates (Snv) or inhibits (Mnanv) mitochondrial respiration in CI-deficient human blood cells, fibroblasts and heart fibres, acting on Complex II of the electron transfer system.
Abbreviation: MitoKit-CII
Reference: MitoKit-CII, Ehinger 2016 Nat Commun
MitoPedia topics:
Media for respirometry
Application in HRR
Preparation
- Both compounds are dissolved in DMSO and stored in aliquots at -20 °C.
- We recommend the following dilutions for reaching the desired concentration in the experiments:
- MitoKit-CII/Succinate-nv: 100 mM stock solution
- MitoKit-CII/Malonate-nv: 10 mM stock solution
SUITbrowser question: Permeable succinate/malonate
Work in progress
