Difference between revisions of "OXPHOS capacity"
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Respiratory capacity of mitochondria in the ADP-activated state of oxidative phosphorylation, at saturating concentrations of ADP, inorganic phosphate, oxygen, and defined reduced substrates (compare [[State 3]]). Since OXPHOS is partially coupled, intrinsic [[uncoupling]] and [[dyscoupling]] contribute to the control of flux in the OXPHOS state or state ''P''. | {{MitoPedia | ||
|abbr=P | |||
|description=Respiratory capacity of mitochondria in the ADP-activated state of oxidative phosphorylation, at saturating concentrations of ADP, inorganic phosphate, oxygen, and defined reduced substrates (compare [[State 3]]). Since OXPHOS is partially coupled, intrinsic [[uncoupling]] and [[dyscoupling]] contribute to the control of flux in the OXPHOS state or state ''P''. | |||
|type=MiP | |||
}} | |||
{{Labeling | |||
|discipline=Mitochondrial Physiology | |||
|preparations=Isolated Mitochondria, Permeabilized Cells or Tissue; Homogenates | |||
|topics=OXPHOS and ETS Capacity, Coupling; Membrane Potential | |||
}} | |||
==References== | ==References== | ||
*Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCH-4W04KR1-3&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a6456620daa0d8cca022b5f934f2cf30 Int. J. Biochem. Cell Biol. 41: 1837–1845]. | *Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. [http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6TCH-4W04KR1-3&_user=10&_rdoc=1&_fmt=&_orig=search&_sort=d&_docanchor=&view=c&_acct=C000050221&_version=1&_urlVersion=0&_userid=10&md5=a6456620daa0d8cca022b5f934f2cf30 Int. J. Biochem. Cell Biol. 41: 1837–1845]. | ||
*Gnaiger E (2010) MitoPathways: Respiratory states and flux control ratios. [http://www.oroboros.at/index.php?respiratorystates Mitochondr. Physiol. Network 12.15: 1-5]. | *Gnaiger E (2010) MitoPathways: Respiratory states and flux control ratios. [http://www.oroboros.at/index.php?respiratorystates Mitochondr. Physiol. Network 12.15: 1-5]. | ||
Revision as of 21:04, 10 September 2010
- high-resolution terminology - matching measurements at high-resolution
OXPHOS capacity
Description
Respiratory capacity of mitochondria in the ADP-activated state of oxidative phosphorylation, at saturating concentrations of ADP, inorganic phosphate, oxygen, and defined reduced substrates (compare State 3). Since OXPHOS is partially coupled, intrinsic uncoupling and dyscoupling contribute to the control of flux in the OXPHOS state or state P.
Abbreviation: P
Labels:
Preparation: Isolated Mitochondria"Isolated Mitochondria" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property., Permeabilized Cells or Tissue; Homogenates"Permeabilized Cells or Tissue; Homogenates" is not in the list (Intact organism, Intact organ, Permeabilized cells, Permeabilized tissue, Homogenate, Isolated mitochondria, SMP, Chloroplasts, Enzyme, Oxidase;biochemical oxidation, ...) of allowed values for the "Preparation" property.
Regulation: OXPHOS and ETS Capacity"OXPHOS and ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property., Coupling; Membrane Potential"Coupling; Membrane Potential" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property.
References
- Gnaiger E (2009) Capacity of oxidative phosphorylation in human skeletal muscle. New perspectives of mitochondrial physiology. Int. J. Biochem. Cell Biol. 41: 1837–1845.
- Gnaiger E (2010) MitoPathways: Respiratory states and flux control ratios. Mitochondr. Physiol. Network 12.15: 1-5.
