Difference between revisions of "Proline dehydrogenase"

Revision as of 08:54, 29 April 2019

high-resolution terminology - matching measurements at high-resolution

Proline dehydrogenase

Description

Proline dehydrogenase (ProDH), L-proline:quinone oxidoreductase, is located on the inner side of the mtIM, oxidizing proline to delta-1-pyrroline-5-carboxylate, with reduction of FAD to FADH₂ and direct entry into the Q-junction, exerting an additive effect of convergent pathways. ProDH is widely distributed in a variety of organisms, is a source of ROS, and may play a role in carcinogenesis.

Abbreviation: ProDH

Reference: Teulier 2016 Proc Biol Sci, Kononczuk et al 2015

Communicated by Garcia-Souza LF and Gnaiger E 2019-04-29

References

Kononczuk J, Czyzewska U, Moczydlowska J, Surażyński A, Palka J, Miltyk W (2015) Proline oxidase (POX) as a target for cancer therapy. Curr Drug Targets 16:1464-9. - »PubMed 26553010«
Teulier L, Weber JM, Crevier J, Darveau CA (2016) Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans. Proc Biol Sci 283: 20160333. - »Bioblast link«

MitoPedia topics: Enzyme

@@ Line 6: / Line 6: @@
   Communicated by [[Garcia-Souza LF]] and Gnaiger E 2019-04-29
 == References ==
-:::# Kononczuk J, Czyzewska U, Moczydlowska J, Surażyński A, Palka J, Miltyk W (2015) Proline oxidase (POX) as a target for cancer therapy. Curr Drug Targets 16:1464-9. - [[https://www.ncbi.nlm.nih.gov/pubmed/26553010 |»PubMed 26553010«]]
+:::# Kononczuk J, Czyzewska U, Moczydlowska J, Surażyński A, Palka J, Miltyk W (2015) Proline oxidase (POX) as a target for cancer therapy. Curr Drug Targets 16:1464-9. - [https://www.ncbi.nlm.nih.gov/pubmed/26553010 »PubMed 26553010«]
 :::# Teulier L, Weber JM, Crevier J, Darveau CA (2016) Proline as a fuel for insect flight: enhancing carbohydrate oxidation in hymenopterans. Proc Biol Sci 283: 20160333. - [[Teulier 2016 Proc Biol Sci |»Bioblast link«]]