Difference between revisions of "Pyruvate dehydrogenase"
From Bioblast
Line 1: | Line 1: | ||
{{MitoPedia | {{MitoPedia | ||
|abbr=PDH | |abbr=PDH | ||
|description='''Pyruvate dehydrogenase''' is the first component enzyme of the [[pyruvate dehydrogenase complex]], which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. | |description='''Pyruvate dehydrogenase''' is the first component enzyme of the [[pyruvate dehydrogenase complex]], which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle. | ||
|info=[[Gnaiger 2014 MitoPathways]], [[Hildyard 2003 Biochem J]] | |info=[[Gnaiger 2014 MitoPathways]], [[Hildyard 2003 Biochem J]] | ||
}} | }} | ||
{{MitoPedia topics | {{MitoPedia topics | ||
|mitopedia topic=Enzyme | |mitopedia topic=Enzyme | ||
}} | }} |
Revision as of 12:32, 29 November 2016
Description
Pyruvate dehydrogenase is the first component enzyme of the pyruvate dehydrogenase complex, which catalyzes oxidative decarboxylation of pyruvate in the mt-matrix, and yields acetyl-CoA. PDH is known as the mitochondrial gatekeeper in the core energy pathway of electron flow into the tricarboxylic acid cycle.
Abbreviation: PDH
Reference: Gnaiger 2014 MitoPathways, Hildyard 2003 Biochem J
MitoPedia topics:
Enzyme