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Property "Has-20abstract" (as page type) with input value "Brown-20adipose-20tissue-20(BAT)-20mitochondria-20are-20distinct-20from-20their-20counterparts-20in-20other-20tissues-20in-20that-20ATP-20production-20is-20not-20their-20primary-20physiologic-20role.-20BAT-20mitochondria-20are-20equipped-20with-20a-20specialized-20protein-20known-20as-20uncoupling-20protein-201-20(UCP1).-20UCP1-20short-2Dcircuits-20the-20electron-20transport-20chain,-20allowing-20mitochondrial-20membrane-20potential-20to-20be-20transduced-20to-20heat,-20making-20BAT-20a-20tissue-20capable-20of-20altering-20energy-20expenditure-20and-20fuel-20metabolism-20in-20mammals-20without-20increasing-20physical-20activity.-20-0A-0AThe-20recent-20discovery-20that-20adult-20humans-20have-20metabolically-20active-20BAT-20has-20rekindled-20an-20interest-20in-20this-20intriguing-20tissue,-20with-20the-20overarching-20aim-20of-20manipulating-20BAT-20function-20to-20augment-20energy-20expenditure-20as-20a-20countermeasure-20for-20obesity-20and-20the-20metabolic-20abnormalities-20it-20incurs.-20Subsequently,-20there-20has-20been-20heightened-20interest-20in-20quantifying-20BAT-20function-20and-20more-20specifically,-20determining-20UCP1-2Dmediated-20thermogenesis-20in-20BAT-20specimens-20-2D-20including-20in-20those-20obtained-20from-20humans.-20-0A-0AIn-20this-20article,-20BAT-20mitochondrial-20bioenergetics-20will-20be-20described-20and-20compared-20with-20more-20conventional-20mitochondria-20in-20other-20tissues.-20The-20biochemical-20methods-20typically-20used-20to-20quantify-20BAT-20mitochondrial-20function-20will-20also-20be-20discussed-20in-20terms-20of-20their-20specificity-20for-20assaying-20UCP1-20mediated-20thermogenesis.-20Finally,-20recent-20data-20concerning-20BAT-20UCP1-20function-20in-20humans-20will-20be-20described-20and-20discussed." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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