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Property "Has-20abstract" (as page type) with input value "We-20introduce-20a-20general-20test-20of-20the-20bioenergetic-20importance-20of-20mtDNA-20(mitochondrial-20DNA)-20variants:-20modular-20kinetic-20analysis-20of-20oxidative-20phosphorylation-20in-20mitochondria-20from-20cybrid-20cells-20with-20constant-20nuclear-20DNA-20but-20different-20mtDNA.-20We-20have-20applied-20this-20test-20to-20the-20hypothesis-20-5BRuiz-2DPesini,-20Mishmar,-20Brandon,-20Procaccio-20and-20Wallace-20(2004)-20Science-20303,-20223-2D226-5D-20that-20particular-20mtDNA-20haplogroups-20(specific-20combinations-20of-20polymorphisms)-20that-20cause-20lowered-20coupling-20efficiency,-20leading-20to-20generation-20of-20less-20ATP-20and-20more-20heat,-20were-20positively-20selected-20during-20radiations-20of-20modern-20humans-20into-20colder-20climates.-20Contrary-20to-20the-20predictions-20of-20this-20hypothesis,-20mitochondria-20from-20Arctic-20haplogroups-20had-20similar-20or-20even-20greater-20coupling-20efficiency-20than-20mitochondria-20from-20tropical-20haplogroups." contains invalid characters or is incomplete and therefore can cause unexpected results during a query or annotation process.

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