Talk:Oroboros Laboratory

Picked up - reading and discussion

• 2017-06-19 Gdynia_2016_Nat Commun - Malic enzyme; cancer

• 2017-06-08 Patent of Q-electrode (1988): Dr P.R. Rich, Glynn Res. Ph., Bodmin; European Patent no.85900699.1 Hungerm (talk) 10:18, 21 June 2017 (CEST)

• 2017-06-08 Pre-print publication: Mitochondria are physiologically maintained at close to 50 °C »Bioblast link«

• 2017-05-30 Quote of the day: ".. oligomycin (complex V inhibitor) determines the amount of ATP production is linked to respiration, FCCP (mitochondrial uncoupler) enables measurement of maximal respiratory capacity, while a combination of rotenone (complex I inhibitor) and antimycin A (complex III inhibitor) determines the reserved respiratory capacity." .. and more: "The mitochondrial network is a major site of ATP production through the coupled integration of the electron transport chain (ETC) with oxidative phosphorylation." - Trotta et al (2017) Disruption of mitochondrial electron transport chain function potentiates the pro-apoptotic effects of MAPK inhibition. JBC Papers in Press. Published on May 25, 2017 as Manuscript M117.786442.

What is reserved respiratory capacity?

• 2017-05-22: Komlodi 2017 Neuropharmacology

• Various

• The rate of oxygen utilization by cells - interesting review beyond ascorbate topic
• The new science of exercise
• Meta-research: Evaluation and improvement of research methods and practices

• Warburg effect

• Warburg O. On the origin of cancer cells. Science 1956; 123:309-314.
• Warburg O. On respiratory impairment in cancer cells. Science 1956; 124:269-270.
• Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009; 324:1029-1033.
• Kim JW, Dang CV. Cancer’s molecular sweet tooth and the Warburg effect. Cancer Res 2006; 66:8927-8930.
• Review: http://online.liebertpub.com/doi/full/10.1089/ars.2016.6750
• Review: http://onlinelibrary.wiley.com/doi/10.1111/febs.13402/full

To our editors

• OROBOROS Mitochondrial Research Laboratory was moved to OROBOROS MitoFit Laboratory

>> Please check redirects from OROBOROS Mitochondrial Research Laboratory

• OROBOROS MitoLab: visiting scientists was moved to OROBOROS MitoFit lab: visiting scientists

>> Please check redirects from OROBOROS MitoLab: visiting scientists

• Rationale: The 'MitoFit Centre of Excellence' or the 'MitoFit Core Facility' will be comprise of the OROBOROS MitoFit Laboratory and the DSL MitoFit Facility.