O2k-Publications: Isolated Mitochondria

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O2k-Publications: Isolated Mitochondria

O2k-Publications in the MiPMap

»O2k-Publications: Topics

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 Was published in yearReferenceOrganismTissue;cell
Vaka 2019 Am J Physiol Regul Integr Comp Physiol2019Vaka VR, Mcmasters KM, Cornelius DC, Ibrahim T, Jayaram A, Usry N, Cunningham MW Jr, Amaral LM, LaMarca BD (2019) Natural killer cells contribute to mitochondrial dysfunction in response to placental ischemia in Reduced Uterine Perfusion Pressure (RUPP) rats. Am J Physiol Regul Integr Comp Physiol 316:R441-R447.Human
Rat
Endothelial;epithelial;mesothelial cell
Genital
McCoin 2019 Am J Physiol Endocrinol Metab2019McCoin CS, Von Schulze A, Allen J, Fuller KN, Xia Q, Koestler DC, Houchen CJ, Maurer A, Dorn Ii GW, Shankar K, Morris EM, Thyfault JP (2019) Sex modulates hepatic mitochondrial adaptations to high fat diet and physical activity. Am J Physiol Endocrinol Metab [Epub ahead of print].MouseLiver
McManus 2019 Cell Metab2019McManus MJ, Picard M, Chen HW, De Haas HJ, Potluri P, Leipzig J, Towheed A, Angelin A, Sengupta P, Morrow RM, Kauffman BA, Vermulst M, Narula J, Wallace DC (2019) Mitochondrial DNA variation dictates expressivity and progression of nuclear DNA mutations causing cardiomyopathy. Cell Metab 29:78-90.MouseHeart
Ruegsegger 2019 FASEB J2019Ruegsegger GN, Manjunatha S, Summer P, Gopala S, Zabeilski P, Dasari S, Vanderboom PM, Lanza IR, Klaus KA, Nair KS (2019) Insulin deficiency and intranasal insulin alter brain mitochondrial function: a potential factor for dementia in diabetes. FASEB J 33:4458-72.MouseNervous system
Munro 2019 Aging Cell2019Munro D, Baldy C, Pamenter ME, Treberg JR (2019) The exceptional longevity of the naked mole-rat may be explained by mitochondrial antioxidant defenses. Aging Cell 18:e12916.Mouse
Other mammals
Heart
Skeletal muscle
Zhu 2019 Aging Cell2019Zhu B, Li Y, Xiang L, Zhang J, Wang L, Guo B, Liang M, Chen L, Xiang L, Dong J, Liu M, Mei W, Li H, Xiang G (2019) Alogliptin improves survival and health of mice on a high-fat diet. Aging Cell 18:e12883.MouseLiver
Flis 2019 Int J Mol Sci2019Flis DJ, Dzik K, Kaczor JJ, Cieminski K, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2019) Swim training modulates mouse skeletal muscle energy metabolism and ameliorates reduction in grip strength in a mouse model of amyotrophic lateral sclerosis. Int J Mol Sci 20:E233.MouseSkeletal muscle
Fisher-Wellman 2019 Cell Rep2019Fisher-Wellman KH, Draper JA, Davidson MT, Williams AS, Narowski TM, Slentz DH, Ilkayeva OR, Stevens RD, Wagner GR, Najjar R, Hirschey MD, Thompson JW, Olson DP, Kelly DP, Koves TR, Grimsrud PA, Muoio DM (2019) Respiratory phenomics across multiple models of protein hyperacylation in cardiac mitochondria reveals a marginal impact on bioenergetics. Cell Rep 26:1557-72.MouseHeart
Skeletal muscle
Carteri 2019 Toxicol Lett2019Carteri RB, Kopzynski A, Menegassi LN, Rodolphi MS, Strogulski NR, Portela LV (2019) Anabolic-androgen steroids effects on bioenergetics responsiveness of synaptic and extrasynaptic mitochondria. Toxicol Lett 307:72-80.MouseNervous system
Detaille 2019 PLoS One2019Detaille D, Pasdois P, Sémont A, Dos Santos P, Diolez P (2019) An old medicine as a new drug to prevent mitochondrial complex I from producing oxygen radicals. PLoS One 14:e0216385.RatHeart
Moretti-Almeida 2019 Fungal Genet Biol2019Moretti-Almeida G, Thomazella DPT, Pereira GAG, Monteiro G (2019) Heterologous expression of an alternative oxidase from Moniliophthora perniciosa in Saccharomyces cerevisiae: antioxidant function and in vivo platform for the study of new drugs against witches' broom disease. Fungal Genet Biol 126:50-55.Saccharomyces cerevisiae
Ferreira 2019 Nat Commun2019Ferreira JCB, Campos JC, Qvit N, Qi X, Bozi LHM, Bechara LRG, Lima VM, Queliconi BB, Disatnik MH, Dourado PMM, Kowaltowski AJ, Mochly-Rosen D (2019) A selective inhibitor of mitofusin 1-βIIPKC association improves heart failure outcome in rats. Nat Commun 10:329.RatHeart
Wang 2019 J Biol Chem2019Wang H, Lu J, Kulkarni S, Zhang W, Gorka JE, Mandel JA, Goetzman ES, Prochownik EV (2019) Metabolic and oncogenic adaptations to pyruvate dehydrogenase inactivation in fibroblasts. J Biol Chem 294:5466-86.RatFibroblast
Lefranc 2019 Hypertension2019Lefranc C, Friederich-Persson M, Braud L, Palacios-Ramirez R, Karlsson S, Boujardine N, Motterlini R, Jaisser F, Nguyen Dinh Cat A (2019) MR (mineralocorticoid receptor) induces adipose tissue senescence and mitochondrial dysfunction leading to vascular dysfunction in obesity. Hypertension 73:458-68.MouseFat
Kakimoto 2019 PLoS One2019Kakimoto PA, Chausse B, Caldeira da Silva CC, Donato Júnior J, Kowaltowski AJ (2019) Resilient hepatic mitochondrial function and lack of iNOS dependence in diet-induced insulin resistance. PLoS One 14:e0211733.MouseLiver
Anderson 2019 Acta Neuropathol2019Anderson CJ, Bredvik K, Burstein SR, Davis C, Meadows SM, Dash J, Case L, Milner TA, Kawamata H, Zuberi A, Piersigilli A, Lutz C, Manfredi G (2019) ALS/FTD mutant CHCHD10 mice reveal a tissue-specific toxic gain-of-function and mitochondrial stress response. Acta Neuropathol [Epub ahead of print].MouseHeart
Stepanova 2019 Antioxid Redox Signal2019Stepanova A, Sosunov S, Niatsetskaya Z, Konrad C, Starkov AA, Manfredi G, Wittig I, Ten V, Galkin A (2019) Redox-dependent loss of flavin by mitochondrial complex I in brain ischemia/reperfusion injury. Antioxid Redox Signal [Epub ahead of print].MouseNervous system
Rojas-Morales 2019 Free Radic Biol Med2019Rojas-Morales P, León-Contreras JC, Aparicio-Trejo OE, Reyes- Ocampo JG, Medina-Campos ON, Jiménez-Osorio AS, González-Reyes S, Marquina- Castillo B, Hernández-Pando R, Barrera-Oviedo D, Sánchez-Lozada LG, Pedraza-Chaverri J, Tapia E (2019) Fasting reduces oxidative stress, mitochondrial dysfunction and fibrosis induced by renal ischemia-reperfusion injury. Free Radic Biol Med 135:60-67.RatKidney
Koop 2019 Int J Cardiol2019Koop AMC, Hagdorn QAJ, Bossers GPL, van Leusden T, Gerding A, van Weeghel M, Vaz FM, Koonen DPY, Silljé HHW, Berger RMF, Bartelds B (2019) Right ventricular pressure overload alters cardiac lipid composition. Int J Cardiol 287:96-105.RatHeart
Mousovich-Neto 2019 Exp Physiol2019Mousovich-Neto F, Matos MS, Costa ACR, de Melo Reis RA, Atella GC, Miranda-Alves L, Carvalho DP, Ketzer LA, Corrêa da Costa VM (2019) Brown adipose tissue remodeling induced by corticosterone in Wistar male rats. Exp Physiol 104:514-28.RatFat
Scheiber 2019 Exp Mol Med2019Scheiber D, Jelenik T, Zweck E, Horn P, Schultheiss HP, Lassner D, Boeken U, Saeed D, Kelm M, Roden M, Westenfeld R, Szendroedi J (2019) High-resolution respirometry in human endomyocardial biopsies shows reduced ventricular oxidative capacity related to heart failure. Exp Mol Med 51:16.HumanHeart
Bundgaard 2019 Sci Rep2019Bundgaard A, James AM, Gruszczyk AV, Martin J, Murphy MP, Fago A (2019) Metabolic adaptations during extreme anoxia in the turtle heart and their implications for ischemia-reperfusion injury. Sci Rep 9:2850.Mouse
Reptiles
Heart
De-Souza-Ferreira 2019 J Neurochem2019de-Souza-Ferreira E, Rios-Neto IM, Martins EL, Galina A (2019) Mitochondria-coupled glucose phosphorylation develops after birth to modulate H2O2 release and calcium handling in rat brain. J Neurochem [Epub ahead of print].RatNervous system
Wang 2019 Free Radic Biol Med2019Wang SQ, Yang XY, Cui SX, Gao ZH, Qu XJ (2019) Heterozygous knockout insulin-like growth factor-1 receptor (IGF-1R) regulates mitochondrial functions and prevents colitis and colorectal cancer. Free Radic Biol Med 134:87-98.MouseHeart
Liver
Endothelial;epithelial;mesothelial cell
Devaux 2019 Front Physiol2019Devaux JBL, Hedges CP, Birch N, Herbert N, Renshaw GMC, Hickey AJR (2019) Acidosis Maintains the Function of Brain Mitochondria in Hypoxia-Tolerant Triplefin Fish: A Strategy to Survive Acute Hypoxic Exposure? Front Physiol 9:1941.FishesNervous system
Rajendran 2019 EMBO Mol Med2019Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456.MouseLiver
Kidney
Heart
Ahn 2019 J Cachexia Sarcopenia Muscle2019Ahn B, Ranjit R, Premkumar P, Pharaoh G, Piekarz KM, Matsuzaki S, Claflin DR, Riddle K, Judge J, Bhaskaran S, Satara Natarajan K, Barboza E, Wronowski B, Kinter M, Humphries KM, Griffin TM, Freeman WM, Richardson A, Brooks SV, Van Remmen H (2019) Mitochondrial oxidative stress impairs contractile function but paradoxically increases muscle mass via fiber branching. J Cachexia Sarcopenia Muscle 10:411-28.MouseSkeletal muscle
Rodriguez-Enriquez 2019 Toxicol Appl Pharmacol2019Rodríguez-Enríquez S, Pacheco-Velázquez SC, Marín-Hernández Á, Gallardo-Pérez JC, Robledo-Cadena DX, Hernández-Reséndiz I, García-García JD, Belmont-Díaz J, López-Marure R, Hernández-Esquivel L, Sánchez-Thomas R, Moreno-Sánchez R (2019) Resveratrol inhibits cancer cell proliferation by impairing oxidative phosphorylation and inducing oxidative stress. Toxicol Appl Pharmacol 370:65-77.RatHeart
Liver
Courtes 2019 Biomed Pharmacother2019Courtes AA, de Carvalho NR, Gonçalves DF, Hartmann DD, da Rosa PC, Dobrachinski F, Franco JL, de Souza DOG, Soares FAA (2019) Guanosine protects against Ca2+-induced mitochondrial dysfunction in rats. Biomed Pharmacother 111: 1438-46.RatLiver
Harhous 2019 J Mol Cell Cardiol2019Harhous Z, Badawi S, Bona NG, Pillot B, Augeul L, Paillard M, Booz GW, Canet-Soulas E, Ovize M, Kurdi M, Bidaux G (2019) Critical appraisal of STAT3 pattern in adult cardiomyocytes. J Mol Cell Cardiol [Epub ahead of print].MouseHeart
Malyala 2019 PLoS Comput Biol2019Malyala S, Zhang Y, Strubbe JO, Bazil JN (2019) Calcium phosphate precipitation inhibits mitochondrial energy metabolism. PLoS Comput Biol 15:e1006719.Guinea pigHeart
Oliveira 2019 Mol Nutr Food Res2019Oliveira TE, Castro É, Belchior T, Andrade ML, Chaves-Filho AB, Peixoto AS, Moreno MF, Ortiz Silva M, Moreira RJ, Inague A, Yoshinaga MY, Miyamoto S, Moustaid-Moussa N, Festuccia WT (2019) Fish oil protects wild type and uncoupling protein 1 deficient mice from obesity and glucose intolerance by increasing energy expenditure. Mol Nutr Food Res 63:e1800813.MouseFat
Kharechkina 2019 Biochim Biophys Acta Gen Subj2019Kharechkina ES, Nikiforova AB, Teplova VV, Odinokova IV, Krestinina OV, Baburina YL, Kruglova SA, Kruglov AG (2019) Regulation of permeability transition pore opening in mitochondria by external NAD(H). Biochim Biophys Acta Gen Subj 1863:771-83.RatLiver
Yan 2019 Int Immunopharmacol2019Yan M, Yu Y, Mao X, Feng J, Wang Y, Chen H, Xie K, Yu Y (2019) Hydrogen gas inhalation attenuates sepsis-induced liver injury in a FUNDC1-dependent manner. Int Immunopharmacol 71:61-7.MouseLiver
MiPNet20.14 AmplexRed H2O2-production2018-11-26
O2k-Protocols
O2k-FluoRespirometry: HRR and simultaneous determination of H2O2 production with Amplex UltraRed.
MouseHeart
MiPNet21.06 SUIT RP2018-06-25
O2k-Protocols
SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.
MiPNet18.10 O2k specifications2018-05-02
Oroboros
O2k-FluoRespirometer: specifications for respirometry and comprehensive OXPHOS analysis.
HumanFibroblast
Tripodi 2018 Biochim Biophys Acta Mol Cell Res2018Tripodi F, Castoldi A, Nicastro R, Reghellin V, Lombardi L, Airoldi C, Falletta E, Maffioli E, Scarcia P, Palmieri L, Alberghina L, Agrimi G, Tedeschi G, Coccetti P (2018) Methionine supplementation stimulates mitochondrial respiration. Biochim Biophys Acta Mol Cell Res 1865:1901-13.Saccharomyces cerevisiae
Sokolov 2018 Mitochondrion2018Sokolov EP, Sokolova IM (2018) Compatible osmolytes modulate mitochondrial function in a marine osmoconformer Crassostrea gigas (Thunberg, 1793). Mitochondrion 45:29-37.MolluscsLung;gill
Budai 2018 Br J Surg2018Budai A, Horváth G, Tretter L, Radák Z, Koltai E, Bori Z, Torma F, Lukáts Á, Röhlich P, Szijártó A, Fülöp A (2018) Mitochondrial function after associating liver partition and portal vein ligation for staged hepatectomy in an experimental model. Br J Surg 106:120-31.RatLiver
Warnsmann 2018 Mech Ageing Dev2018Warnsmann V, Meyer N, Hamann A, Kögel D, Osiewacz HD (2018) A novel role of the mitochondrial permeability transition pore in (-)-gossypol-induced mitochondrial dysfunction. Mech Ageing Dev 170:45-58.Fungi
McLaughlin 2018 Biochem Biophys Res Commun2018McLaughlin KL, McClung JM, Fisher-Wellman KH (2018) Bioenergetic consequences of compromised mitochondrial DNA repair in the mouse heart. Biochem Biophys Res Commun 504:742-48.MouseHeart
Flis 2018 Oxid Med Cell Longev2018Flis DJ, Dzik K, Kaczor JJ, Halon-Golabek M, Antosiewicz J, Wieckowski MR, Ziolkowski W (2018) Swim training modulates skeletal muscle energy metabolism, oxidative stress, and mitochondrial cholesterol content in amyotrophic lateral sclerosis mice. Oxid Med Cell Longev 5940748.MouseSkeletal muscle
Urazov 2018 Sovrem Tekhnologii Med2018Urazov MD, Astrakhanova TA, Usenko AV, Mishchenko TA, Schelchkova NA, Kravchenko GA, Vedunova MV, Mitroshina EV (2018) New aspects of central nervous system adaptation to prenatal hypoxia. Sovrem Tekhnologii Med 10:60-68.MouseNervous system
Logan 2018 Thesis2018Logan C (2018) Nitrate and nitrite differentially affect respiration in zebrafish during exercise. Honors Baccalaureate of Science in Nutrition p44.ZebrafishSkeletal muscle
Du 2018 Environ Sci Technol2018Du SNN, McCallum ES, Vaseghi-Shanjani M, Choi JA, Warriner TR, Balshine S, Scott GR (2018) Metabolic costs of exposure to wastewater effluent lead to compensatory adjustments in respiratory physiology in bluegill sunfish. Environ Sci Technol 52:801-11.FishesLiver
Ramil 2018 Thesis2018Ramil LR, Gulbinas A, Cesna V (2018) “HIPEC” hyperthermic intraperitoneal chemotherapy. Evaluation of intraperitoneal free cancer cells. Master's Thesis.HumanEndothelial;epithelial;mesothelial cell
Christensen 2018 Diabetes Metab Res Rev2018Christensen M, Schiffer TA, Gustafsson H, Krag SP, Nørregaard R, Palm F (2018) Metformin attenuates renal medullary hypoxia in diabetic nephropathy through uncoupling protein-2 inhibition. Diabetes Metab Res Rev 21:e3091.RatKidney
Collard 2018 Mol Cell Biol2018Collard R, Majtan T, Park I, Kraus JP (2018) Import of TAT-conjugated propionyl coenzyme A carboxylase using models of propionic acidemia. Mol Cell Biol 38. pii: e00491-17.MouseLiver
Reutzel 2018 Oxid Med Cell Longev2018Reutzel M, Grewal R, Silaidos C, Zotzel J, Marx S, Tretzel J, Eckert GP (2018) Effects of long-term treatment with a blend of highly purified olive secoiridoids on cognition and brain ATP levels in aged NMRI mice. Oxid Med Cell Longev 2018:4070935.MouseNervous system
Mikulas 2018 Dent Mater2018Mikulás K, Hermann P, Gera I, Komlódi T, Horváth G, Ambrus A, Tretter L (2018) Triethylene glycol dimethacrylate impairs bioenergetic functions and induces oxidative stress in mitochondria via inhibiting respiratory Complex I. Dent Mater 34:e166-e181.Guinea pigNervous system
Clarke 2018 Methods Mol Biol2018Clarke KJ, Porter RK (2018) The importance of calcium ions for determining mitochondrial glycerol-3-phosphate dehydrogenase activity when measuring uncoupling protein 1 (UCP1) function in mitochondria isolated from brown adipose tissue. Methods Mol Biol 1782:325-36.RatFat
Davila 2018 Elife2018Davila A, Liu L, Chellappa K, Redpath P, Nakamaru-Ogiso E, Paolella LM, Zhang Z, Migaud ME, Rabinowitz JD, Baur JA (2018) Nicotinamide adenine dinucleotide is transported into mammalian mitochondria. Elife 7:e33246.MouseSkeletal muscle
Liver
Cardinale 2018 Thesis2018Cardinale DA (2018) The significance of mitochondrial respiratory function in regulating oxygen uptake and performance in humans. PhD Thesis 99.HumanSkeletal muscle
Kang 2018 Exp Mol Med2018Kang YC, Son M, Kang S, Im S, Piao Y, Lim KS, Song MY, Park KS, Kim YH, Pak YK (2018) Cell-penetrating artificial mitochondria-targeting peptide-conjugated metallothionein 1A alleviates mitochondrial damage in Parkinson's disease models. Exp Mol Med 50:105.HumanNervous system
Wang 2018 J Nutr Biochem2018Wang Y, Fouret G, Bonafos B, Blachnio-Zabielska A, Leroy T, Crouzier D, Barea B, Gaillet S, Moro C, Lecomte J, Coudray C, Feillet-Coudray C (2018) Long-term follow-up of muscle lipid accumulation, mitochondrial activity and oxidative stress and their relationship with impaired glucose homeostasis in high fat high fructose diet-fed rats. J Nutr Biochem 64:182-97.RatSkeletal muscle
Van Erp 2018 Sci Rep2018Van Erp AC, Rebolledo RA, Hoeksma D, Jespersen NR, Ottens PJ, Nørregaard R, Pedersen M, Laustsen C, Burgerhof JGM, Wolters JC, Ciapaite J, Bøtker HE, Leuvenink HGD, Jespersen B (2018) Organ-specific responses during brain death: increased aerobic metabolism in the liver and anaerobic metabolism with decreased perfusion in the kidneys. Sci Rep 8:4405.RatLiver
Kidney
Martinez 2018 Arch Biochem Biophys2018Martínez JH, Fuentes F, Vanasco V, Alvarez S, Alaimo A, Cassina A, Coluccio Leskow F, Velazquez F (2018) Alpha-synuclein mitochondrial interaction leads to irreversible translocation and complex I impairment. Arch Biochem Biophys 651:1-12.RatNervous system
Siira 2018 EMBO Rep2018Siira SJ, Rossetti G, Richman TR, Perks K, Ermer JA, Kuznetsova I, Hughes L, Shearwood AJ, Viola HM, Hool LC, Rackham O, Filipovska A (2018) Concerted regulation of mitochondrial and nuclear non-coding RNAs by a dual-targeted RNase Z. EMBO Rep 19:e46198.MouseHeart
Lu 2018 Cell Rep2018Lu Z, Cui Y, Wei X, Gao P, Zhang H, Wei X, Li Q, Sun F, Yan Z, Zheng H*, Yang G, Liu D, Zhu Z (2018) Deficiency of PKD2L1 (TRPP3) exacerbates pathological cardiac hypertrophy by augmenting NCX1-mediated mitochondrial calcium overload. Cell Rep 24:1639-52.MouseHeart
Fink 2018 J Biol Chem2018Fink BD, Bai F, Yu L, Sheldon RD, Sharma A, Taylor EB, Sivitz WI (2018) Oxaloacetic acid mediates ADP-dependent inhibition of mitochondrial complex II-driven respiration. J Biol Chem 293:19932-41.MouseSkeletal muscle
Mills 2018 Nature2018Mills EL, Ryan DG, Prag HA, Dikovskaya D, Menon D, Zaslona Z, Jedrychowski MP, Costa ASH, Higgins M, Hams E, Szpyt J, Runtsch MC, King MS, McGouran JF, Fischer R, Kessler BM, McGettrick AF, Hughes MM, Carroll RG, Booty LM, Knatko EV, Meakin PJ, Ashford MLJ, Modis LK, Brunori G, Sévin DC, Fallon PG, Caldwell ST, Kunji ERS, Chouchani ET, Frezza C, Dinkova-Kostova AT, Hartley RC, Murphy MP, O'Neill LA (2018) Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1. Nature 556:113-7.RatLiver
Ko 2018 Pflugers Arch2018Ko TH, Marquez JC, Kim HK, Jeong SH, Lee S, Youm JB, Song IS, Seo DY, Kim HJ, Won DN, Cho KI, Choi MG, Rhee BD, Ko KS, Kim N, Won JC, Han J (2018) Resistance exercise improves cardiac function and mitochondrial efficiency in diabetic rat hearts. Pflugers Arch 470:263-75.RatHeart
Cruz 2018 Chem Biol Interact2018Cruz LC, Ecker A, Rodrigues NR, Martins IK, Posser T, Maciel FE, Vargas MA, Barbosa NV, Franco JL (2018) Honey protects against wings posture error and molecular changes related to mitochondrial pathways induced by hypoxia/reoxygenation in adult Drosophila melanogaster. Chem Biol Interact 291:245-52.Drosophila
Johnson 2018 J Mol Cell Cardiol2018Johnson JM, Ferrara PJ, Verkerke ARP, Coleman CB, Wentzler EJ, Neufer PD, Kew KA, de Castro Brás LE, Funai K (2018) Targeted overexpression of catalase to mitochondria does not prevent cardioskeletal myopathy in Barth syndrome. J Mol Cell Cardiol 121:94-102.MouseHeart
Skeletal muscle
Sprenger 2018 EMBO Mol Med2018Sprenger HG, Wani G, Hesseling A, König T, Patron M, MacVicar T, Ahola S, Wai T, Barth E, Rugarli EI, Bergami M, Langer T (2018) Loss of the mitochondrial i-AAA protease YME1L leads to ocular dysfunction and spinal axonopathy. EMBO Mol Med 11:e9288.MouseNervous system
Rampello 2018 Microb Cell2018Rampello NG, Stenger M, Westermann B, Osiewacz HD (2018) Impact of F1Fo-ATP-synthase dimer assembly factors on mitochondrial function and organismic aging. Microb Cell 5:198–207. .Fungi
Stepanova 2018 J Cereb Blood Flow Metab2018Stepanova A, Konrad C, Guerrero-Castillo S, Manfredi G, Vannucci S, Arnold S, Galkin A (2018) Deactivation of mitochondrial complex I after hypoxia-ischemia in the immature brain. J Cereb Blood Flow Metab [Epub ahead of print].RatNervous system
Kauppila 2018 Thesis2018Kauppila JHK (2018) Generating mammalian mitochondrial disease models with mitochondrial DNA mutations. PhD Thesis p120.MouseHeart
Liver
Chabi 2018 J Bioenerg Biomembr2018Chabi B, Fouret G, Lecomte J, Cortade F, Pessemesse L, Baati N, Coudray C, Lin L, Tong Q, Wrutniak-Cabello C, Casas F, Feillet-Coudray C (2018) Skeletal muscle overexpression of short isoform Sirt3 altered mitochondrial cardiolipin content and fatty acid composition. J Bioenerg Biomembr 50:131-42.MouseSkeletal muscle
Zhang 2018 Cardiovasc Diabetol2018Zhang X, Zhang Z, Yang Y, Suo Y, Liu R, Qiu J, Zhao Y, Jiang N, Liu C, Tse G, Li G, Liu T (2018) Alogliptin prevents diastolic dysfunction and preserves left ventricular mitochondrial function in diabetic rabbits. Cardiovasc Diabetol 17:160.RabbitHeart
Silva 2018 Methods Mol Biol2018Silva AM, Oliveira PJ (2018) Evaluation of respiration with clark-type electrode in isolated mitochondria and permeabilized animal cells. Methods Mol Biol 1782:7-29.
Uribe-Alvarez 2018 Microbiologyopen2018Uribe-Alvarez C, Chiquete-Félix N, Morales-García L, Bohórquez-Hernández A, Delgado-Buenrostro NL, Vaca L, Peña A, Uribe-Carvajal S (2018) Wolbachia pipientis grows in Saccharomyces cerevisiae evoking early death of the host and deregulation of mitochondrial metabolism. Microbiologyopen 8:e00675.Saccharomyces cerevisiae
Razak 2018 RUMeS2018Razak SHA, Hassan H, Hakimi NH, Rani NA, Ibrahim NF, Ngah WZW, Makpol S, Damanhuri MHA, Karim NA, Tan JK (2018) Isolation of mitochondria and measurement of oxygen consumption rate by high-resolution respirometry in rat hippocampus. RUMeS 6:11-18.RatNervous system
Dogan 2018 Cell Metab2018Dogan SA, Cerutti R, Benincá C, Brea-Calvo G, Jacobs HT, Zeviani M, Szibor M, Viscomi C (2018) Perturbed redox signaling exacerbates a mitochondrial myopathy. Cell Metab 28:764-77.MouseSkeletal muscle
Lu 2018 Cell Discov2018Lu Z, Wei X, Sun F, Zhang H, Gao P, Pu Y, Wang A, Chen J, Tong W, Li Q, Zhou X, Yan Z, Zheng H, Yang G, Huang Y, Liu D, Zhu Z (2018) Non-insulin determinant pathways maintain glucose homeostasis upon metabolic surgery. Cell Discov 4:58.RatSkeletal muscle
Zimin 2018 Br J Anaesth2018Zimin PI, Woods CB, Kayser EB, Ramirez JM, Morgan PG, Sedensky MM (2018) Isoflurane disrupts excitatory neurotransmitter dynamics via inhibition of mitochondrial complex I. Br J Anaesth 120:1019-32.MouseNervous system
Chung 2018 Integr Comp Biol2018Chung DJ, Healy TM, McKenzie JL, Chicco AJ, Sparagna GC, Schulte PM (2018) Mitochondria, temperature, and the pace of life. Integr Comp Biol 58:578-90.FishesHeart
Nervous system
Liver
Rundle 2018 Environ Sci Technol2018Rundle K, Sharaf M, Stevens D, Kamunde C, Van Den Heuvel MR (2018) Oil sands-derived naphthenic acids are oxidative uncouplers and impair electron transport in isolated mitochondria. Environ Sci Technol 52:10803-11.FishesLiver
Civiletto 2018 EMBO Mol Med2018Civiletto G, Dogan SA, Cerutti R, Fagiolari G, Moggio M, Lamperti C, Benincá C, Viscomi C, Zeviani M (2018) Rapamycin rescues mitochondrial myopathy via coordinated activation of autophagy and lysosomal biogenesis. EMBO Mol Med 10:e8799.MouseSkeletal muscle
Wu 2018 Adv Sci2018Wu S, Zhang A, Li S, Chatterjee S, Qi R, Segura-Ibarra V, Ferrari M, Gupte A, Blanco E, Hamilton DJ (2018) Polymer functionalization of isolated mitochondria for cellular transplantation and metabolic phenotype alteration. Adv Sci 1700530.MouseLiver
Kleszczynski 2018 Int J Mol Sci2018Kleszczyński K, Bilska B, Stegemann A, Flis DJ, Ziolkowski W, Pyza E, Luger TA, Reiter RJ, Böhm M, Slominski AT (2018) Melatonin and its metabolites ameliorate UVR-induced mitochondrial oxidative stress in human MNT-1 melanoma cells. Int J Mol Sci 19:E3786.MouseLiver
Fuhrmann 2018 Cell Mol Life Sci2018Fuhrmann DC, Wittig I, Dröse S, Schmid T, Dehne N, Brüne B (2018) Degradation of the mitochondrial complex I assembly factor TMEM126B under chronic hypoxia. Cell Mol Life Sci 75:3051-67.Human
Belosludtsev 2018 Biochemistry (Mosc)2018Belosludtsev KN, Belosludtseva NV, Tenkov KS, Sharapov VA, Kosareva EA, Dubinin MV (2018) Effect of dequalinium on respiration and the inner membrane permeability of rat liver mitochondria. Biochemistry (Mosc) 12:121–27.RatLiver
Rodrigues 2018 Free Radic Biol Med2018Rodrigues NR, Macedo GE, Martins IK, Gomes KK, de Carvalho NR, Posser T, Franco JL (2018) Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila. Free Radic Biol Med 120:395-406.Drosophila
Nan 2018 Circ Res2018Nan J, Hu H, Sun Y, Zhu L, Wang Y, Zhong Z, Zhao J, Zhang N, Wang Y, Wang Y, Ye J, Zhang L, Hu X, Zhu W, Wang J (2018) TNFR2 stimulation promotes mitochondrial fusion via Stat3- and NF-kB-dependent activation of OPA1 expression. Circ Res 121:392-410.MouseHeart
Rossignoli 2018 J Nutr Biochem2018Rossignoli CP, Dechandt CRP, Souza AO, Sampaio IH, Vicentini TM, Teodoro BG, Neto MPC, Ferrari GD, Couto-Lima CA, Alberici LC (2018) Effects of intermittent dietary supplementation with conjugated linoleic acid and fish oil (EPA/DHA) on body metabolism and mitochondrial energetics in mice. J Nutr Biochem 60:16-23.MouseFat
Liver
Nervous system
Skeletal muscle
Takahashi 2018 Sci Rep2018Takahashi K, Miura Y, Ohsawa I, Shirasawa T, Takahashi M (2018) In vitro rejuvenation of brain mitochondria by the inhibition of actin polymerization. Sci Rep 8:15585.MouseNervous system
Logan 2018 Mol Metab2018Logan S, Pharaoh GA, Marlin MC, Masser DR, Matsuzaki S, Wronowski B, Yeganeh A, Parks EE, Premkumar P, Farley JA, Owen DB, Humphries KM, Kinter M, Freeman WM, Szweda LI, Van Remmen H, Sonntag WE (2018) Insulin-like growth factor receptor signaling regulates working memory, mitochondrial metabolism, and amyloid-β uptake in astrocytes. Mol Metab 9:141-55.MouseNervous system
Cardinale 2018 Front Physiol2018Cardinale DA, Larsen FJ, Schiffer TA, Morales-Alamo D, Ekblom B, Calbet JAL, Holmberg HC, Boushel R (2018) Superior intrinsic mitochondrial respiration in women than in men. Front Physiol 9:1133.HumanSkeletal muscle
Einer 2018 Cell Mol Gastroenterol Hepatol2018Einer C, Leitzinger C, Lichtmannegger J, Eberhagen C, Rieder T, Borchard S, Wimmer R, Denk G, Popper B, Neff F, Polishchuk EV, Polishchuk RS, Hauck SM, von Toerne C, Müller JC, Karst U, Baral BS, DiSpirito AA, Kremer AE, Semrau J, Weiss KH, Hohenester S, Zischka H (2018) A high calorie diet aggravates mitochondrial dysfunction and triggers severe liver damage in Wilson disease rats. Cell Mol Gastroenterol Hepatol 7:571-96.RatLiver
Becker 2018 EMBO Rep2018Becker C, Kukat A, Szczepanowska K, Hermans S, Senft K, Brandscheid CP, Maiti P, Trifunovic A (2018) CLPP deficiency protects against metabolic syndrome but hinders adaptive thermogenesis. EMBO Rep 19. pii: e45126.MouseLiver
Fat
Apostolopoulou 2018 Thesis2018Apostolopoulou M (2018) Determinants of insulin sensitivity in obesity and recent-onset type 2 diabetes mellitus. PhD Thesis 77.HumanLiver
Kauppila 2018 Nucleic Acids Res2018Kauppila JHK, Bonekamp NA, Mourier A, Isokallio MA, Just A, Kauppila TES, Stewart JB, Larsson NG (2018) Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. Nucleic Acids Res 46:6642-69.Mouse
Belosludtsev 2018 Biochim Biophys Acta2018Belosludtsev KN, Belosludtseva NV, Talanov EY, Tenkov KS, Starinets VS, Agafonov AV, Pavlik LL, Dubinin MV (2018) Effect of bedaquiline on the functions of rat liver mitochondria. Biochim Biophys Acta 1861:288-97.RatLiver
Monaco 2018 Am J Physiol Regul Integr Comp Physiol2018Monaco CMF, Miotto PM, Huber JS, van Loon LJC, Simpson JA, Holloway GP (2018) Sodium nitrate supplementation alters mitochondrial H2O2 emission but does not improve mitochondrial oxidative metabolism in the heart of healthy rats. Am J Physiol Regul Integr Comp Physiol 315:R191-R204.RatHeart
Menezes-Filho 2018 Biochim Biophys Acta Bioenerg2018Menezes-Filho SL, Amigo I, Luévano-Martínez LA, Kowaltowski AJ (2018) Fasting promotes functional changes in liver mitochondria. Biochim Biophys Acta Bioenerg 1860:129-35.MouseLiver
Ravasz 2018 Biochim Biophys Acta2018Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2018) Reduction of 2-methoxy-1,4-naphtoquinone by mitochondrially-localized Nqo1 yielding NAD+ supports substrate-level phosphorylation during respiratory inhibition. Biochim Biophys Acta 1859:909-24.MouseLiver
Petiz 2018 Chem Biol Interact2018Petiz LL, Pires ADRA, Echevarria A, Rodrigues-Santos CE, Eliane Merlin Rocha M, Acco A, Cadena SMSC (2018) Effects of a new antiprotozoal drug, N,N'-diphenyl-4-methoxy-benzamidine, on energy-linked functions of rat liver mitochondria. Chem Biol Interact 279:34-42.RatLiver
Sahl 2018 Anal Biochem2018Sahl RE, Morville T, Kraunsøe R, Dela F, Helge JW, Larsen S (2018) Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies. Anal Biochem 556:119-24.Human
Mouse
Saccharomyces cerevisiae
Skeletal muscle
Francisco 2018 J Neurochem2018Francisco A, Ronchi JA, Navarro CDC, Figueira TR, Castilho RF (2018) Nicotinamide nucleotide transhydrogenase is required for brain mitochondrial redox balance under hampered energy substrate metabolism and high-fat diet. J Neurochem 147:663-77.MouseNervous system
Christen 2018 Free Radic Biol Med2018Christen F, Desrosiers V, Dupont-Cyr BA, Vandenberg GW, Le François NR, Tardif JC, Dufresne F, Lamarre SG, Blier PU (2018) Thermal tolerance and thermal sensitivity of heart mitochondria: Mitochondrial integrity and ROS production. Free Radic Biol Med 116:11-8.FishesHeart
Schiffer 2018 PLoS One2018Schiffer TA, Christensen M, Gustafsson H, Palm F (2018) The effect of inactin on kidney mitochondrial function and production of reactive oxygen species. PLoS One 13:e0207728.RatKidney
Jelenik 2018 Diabetes2018Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J (2018) Insulin resistance and vulnerability to cardiac ischemia. Diabetes 67:2695-702.Human
Mouse
Heart
Chung 2018 J Exp Biol2018Chung DJ, Sparagna GC, Chicco AJ, Schulte PM (2018) Patterns of mitochondrial membrane remodeling parallel functional adaptations to thermal stress. J Exp Biol 221. pii: jeb174458.FishesLiver
Astrakhanova 2018 Sovrem Tekhnologii Med2018Astrakhanova ТА, Urazov МD, Usenko АV, Mitroshina ЕV, Mishchenko ТА, Schelchkova NА, Vedunova МV (2018) BDNF-mediated regulation of the brain mitochondria functional state in hypoxia. Sovrem Tekhnologii Med 10:88-94.MouseNervous system
Gam 2018 Acta Diabetol2018Gam CMBF, Mortensen OH, Larsen LH, Poulsen SS, Qvortrup K, Mathiesen ER, Damm P, Quistorff B (2018) Diabetes, myometrium, and mitochondria in pregnant women at term. Acta Diabetol 55:999-1010.HumanGenital
Treberg 2018 Comp Biochem Physiol B Biochem Mol Biol2018Treberg JR, Braun K, Zacharias P, Kroeker K (2018) Multidimensional mitochondrial energetics: Application to the study of electron leak and hydrogen peroxide metabolism. Comp Biochem Physiol B Biochem Mol Biol 224:121-28.Mouse
Rat
Skeletal muscle
Burstein 2018 Hum Mol Genet2018Burstein SR, Valsecchi F, Kawamata H, Bourens M, Zeng R, Zuberi A, Milner TA, Cloonan SM, Lutz C, Barrientos A, Manfredi G (2018) In vitro and in vivo studies of the ALS-FTLD protein CHCHD10 reveal novel mitochondrial topology and protein interactions. Hum Mol Genet 27:160-77.Human
Mouse
Heart
Skeletal muscle
Nervous system
HEK
Von Schulze 2018 J Physiol2018Von Schulze A, McCoin CS, Onyekere C, Allen J, Geiger P, Dorn GW, Morris EM, Thyfault JP (2018) Hepatic mitochondrial adaptations to physical activity: impact of sexual dimorphism, PGC1α, and BNIP3 mediated mitophagy. J Physiol 596:6157-71.MouseLiver
Aparicio-Trejo 2018 Free Radic Biol Med2018Aparicio-Trejo OE, Reyes-Fermín LM, Briones-Herrera A, Tapia E, León-Contreras JC, Hernández-Pando R, Sánchez-Lozada LG, Pedraza-Chaverri J (2018) Protective effects of N-acetyl-cysteine in mitochondria bioenergetics, oxidative stress, dynamics and S-glutathionylation alterations in acute kidney damage induced by folic acid. Free Radic Biol Med 130:379-96.RatKidney
Doerrier 2018 Methods Mol Biol2018Doerrier C, Garcia-Souza LF, Krumschnabel G, Wohlfarter Y, Mészáros AT, Gnaiger E (2018) High-Resolution FluoRespirometry and OXPHOS protocols for human cells, permeabilized fibers from small biopsies of muscle, and isolated mitochondria. Methods Mol Biol 1782:31-70.Human
Mouse
Rat
Saccharomyces cerevisiae
Heart
Skeletal muscle
Endothelial;epithelial;mesothelial cell
Blood cells
HEK
Platelet
Sims 2018 JCI Insight2018Sims CA, Guan Y, Mukherjee S, Singh K, Botolin P, Davila A Jr, Baur JA (2018) Nicotinamide mononucleotide preserves mitochondrial function and increases survival in hemorrhagic shock. JCI Insight 3:120182.RatLiver
Kidney
Ederer 2018 Int J Mol Sci2018Ederer KA, Jin K, Bouslog S, Wang L, Gorman GS, Rowe GC, Abadir P, Raftery D, Moellering D, Promislow D, Jumbo-Lucioni P, De Luca M (2018) Age- and genotype-specific effects of the angiotensin-converting enzyme inhibitor lisinopril on mitochondrial and metabolic parameters in Drosophila melanogaster. Int J Mol Sci 19:3351.Drosophila
Zhang 2018 J Mol Cell Cardiol2018Zhang G, Sheng M, Wang J, Teng T, Sun Y, Yang Q, Xu Z (2018) Zinc improves mitochondrial respiratory function and prevents mitochondrial ROS generation at reperfusion by phosphorylating STAT3 at Ser727. J Mol Cell Cardiol 118:169-82.MouseHeart
Hayward 2018 Thesis2018Hayward L (2018) The effect of anoxia on mitochondrial function in a hibernator (Ictidomys tridecemlineatus). Master's Thesis 57.Other mammalsLiver
Cardinale 2018 Acta Physiol (Oxf)2018Cardinale DA, Larsen FJ, Jensen-Urstad M, Rullman E, Søndergaard H, Morales-Alamo D, Ekblom B, Calbet JAL, Boushel R (2018) Muscle mass and inspired oxygen influence oxygen extraction at maximal exercise: Role of mitochondrial oxygen affinity. Acta Physiol (Oxf) 225:e13110.HumanSkeletal muscle
Manakov 2018 J Physiol Biochem2018Manakov D, Kolar D, Zurmanova J, Pravenec M, Novotny J (2018) Changes in the activity of some metabolic enzymes in the heart of SHR rat incurred by transgenic expression of CD36. J Physiol Biochem 74:479-89.RatHeart
Schilperoort 2018 EMBO Mol Med2018Schilperoort M, van Dam AD, Hoeke G, Shabalina IG, Okolo A, Hanyaloglu AC, Dib LH, Mol IM, Caengprasath N, Chan YW, Damak S, Miller AR, Coskun T, Shimpukade B, Ulven T, Kooijman S, Rensen PC, Christian M (2018) The GPR120 agonist TUG-891 promotes metabolic health by stimulating mitochondrial respiration in brown fat. EMBO Mol Med 10:e8047.MouseFat
Schiffer 2018 Am J Physiol Renal Physiol2018Schiffer TA, Gustafsson H, Palm F (2018) Kidney outer medulla mitochondria are more efficient compared with cortex mitochondria as a strategy to sustain ATP production in a suboptimal environment. Am J Physiol Renal Physiol 315:F677-F681.RatKidney
Niu 2018 Cancer Metab2018Niu X, Chen YJ, Crawford PA, Patti GJ (2018) Transport-exclusion pharmacology to localize lactate dehydrogenase activity within cells. Cancer Metab 6:19.HumanHeLa
Chen 2018 Hum Mol Genet2018Chen A, Tiosano D, Guran T, Baris HN, Bayram Y, Mory A, Shapiro-Kulnane L, Hodges CA, Coban Akdemir Z, Turan S, Jhangiani SN, van den Akker F, Hoppel CL, Salz HK, Lupski JR, Buchner DA (2018) Mutations in the mitochondrial ribosomal protein MRPS22 lead to primary ovarian insufficiency. Hum Mol Genet 27:1913-26.HumanEndothelial;epithelial;mesothelial cell
Fibroblast
Robb 2018 J Biol Chem2018Robb EL, Hall AR, Prime TA, Eaton S, Szibor M, Viscomi C, James AM, Murphy MP (2018) Control of mitochondrial superoxide production by reverse electron transport at complex I. J Biol Chem 293:9869-79.RatHeart
Chen 2018 Endocrinology2018Chen Y, McCommis KS, Ferguson D, Hall AM, Harris CA, Finck BN (2018) Inhibition of the mitochondrial pyruvate carrier by tolylfluanid. Endocrinology 159:609-21.MouseFat
Nacarelli 2018 Geroscience2018Nacarelli T, Azar A, Altinok O, Orynbayeva Z, Sell C (2018) Rapamycin increases oxidative metabolism and enhances metabolic flexibility in human cardiac fibroblasts. Geroscience [Epub ahead of print].HumanHeart
Fibroblast
Treberg 2018 Redox Biol2018Treberg JR, Braun K, Selseleh P (2018) Mitochondria can act as energy-sensing regulators of hydrogen peroxide availability. Redox Biol 20:483-88.RatSkeletal muscle
Friederich-Persson 2018 Acta Physiol (Oxf)2018Friederich-Persson M, Persson P, Hansell P, Palm F (2018) Deletion of Uncoupling Protein-2 reduces renal mitochondrial leak respiration, intrarenal hypoxia and proteinuria in a mouse model of type 1 diabetes. Acta Physiol (Oxf) 223:e13058.MouseKidney
Kappler 2018 Thesis2018Kappler L (2018) Method development for valid high‐resolution profiling of mitochondria and Omics investigation of mitochondrial adaptions to excess energy intake and physical exercise. Dissertation p181.Human
Mouse
Skeletal muscle
Liver
Other cell lines
Weisz 2018 Hum Mol Genet2018Weisz ED, Towheed A, Monyak RE, Toth MS, Wallace DC, Jongens TA (2018) Loss of Drosophila FMRP leads to alterations in energy metabolism and mitochondrial function. Hum Mol Genet 27:95-106.DrosophilaSkeletal muscle
Paech 2018a Toxicology2018Paech F, Mingard C, Grünig D, Abegg VF, Bouitbir J, Krähenbühl S (2018) Mechanisms of mitochondrial toxicity of the kinase inhibitors ponatinib, regorafenib and sorafenib in human hepatic HepG2 cells. Toxicology 395:34-44.Human
Mouse
Liver
Other cell lines
Komlodi 2018 J Bioenerg Biomembr2018Komlódi T, Geibl FF, Sassani M, Ambrus A, Tretter L (2018) Membrane potential and delta pH dependency of reverse electron transport-associated hydrogen peroxide production in brain and heart mitochondria. J Bioenerg Biomembr 10.1007/s10863-018-9766-8.Guinea pigHeart
Nervous system
Fisher-Wellman 2018 Cell Rep2018Fisher-Wellman KH, Davidson MT, Narowski TM, Lin CT, Koves TR, Muoio DM (2018) Mitochondrial diagnostics: A multiplexed assay platform for comprehensive assessment of mitochondrial energy fluxes. Cell Rep 24:3593-606.MouseHeart
Skeletal muscle
Bryant 2018 Thesis2018Bryant HJ (2018) The role of mitochondrial uncoupling in temperature responses in Atlantic killifish, Fundulus heteroclitus. Master's Thesis p126.FishesNervous system
Liver
Fat
De Lima Junior 2018 EBioMedicine2018De Lima Junior JC, Souza GF, Moura-Assis A, Gaspar RS, Gaspar JM, Rocha AL, Ferrucci DL, Lima TI, Victório SC, Bonfante ILP, Cavaglieri CR, Pareja JC, Brunetto SQ, Ramos CD, Geloneze B, Mori MA, Silveira LR, Segundo GRS, Ropelle ER, Velloso LA (2018) Abnormal brown adipose tissue mitochondrial structure and function in IL10 deficiency. EBioMedicine 39:436-47.MouseFat
Perks 2018 Cell Rep2018Perks KL, Rossetti G, Kuznetsova I, Hughes LA, Ermer JA, Ferreira N, Busch JD, Rudler DL, Spahr H, Schöndorf T, Shearwood AJ, Viola HM, Siira SJ, Hool LC, Milenkovic D, Larsson NG, Rackham O, Filipovska A (2018) PTCD1 is required for 16S rRNA maturation complex stability and mitochondrial ribosome assembly. Cell Rep 23:127-42.MouseHeart
Scott 2018 Integr Comp Biol2018Scott GR, Guo KH, Dawson NJ (2018) The mitochondrial basis for adaptive variation in aerobic performance in high-altitude deer mice. Integr Comp Biol 58:506-18.MouseHeart
Skeletal muscle
Rekuviene 2018 Thesis2018Rekuvienė E (2018) Effect of respiratory complex I inhibitors on mitochondrial permeability transition and cell viability during brain ischemia. Doctoral Dissertation 138.RatNervous system
Ale-Agha 2018 PLOS Biol2018Ale-Agha N, Goy C, Jakobs P, Spyridopoulos I, Gonnissen S, Dyballa-Rukes N, Aufenvenne K, von Ameln F, Zurek M, Spannbrucker T, Eckermann O, Jakob S, Gorressen S, Abrams M, Grandoch M, Fischer JW, Köhrer K, Deenen R, Unfried K, Altschmied J, Haendeler J (2018) CDKN1B/p27 is localized in mitochondria and improves respiration-dependent processes in the cardiovascular system - New mode of action for caffeine. PLOS Biol 6:e2004408.MouseHeart
Augustynek 2018 Int J Mol Sci2018Augustynek B, Koprowski P, Rotko D, Kunz WS, Szewczyk A, Kulawiak B (2018) Mitochondrial BK channel openers CGS7181 and CGS7184 exhibit cytotoxic properties. Int J Mol Sci 19. pii: E353.RatNervous system
Rajasekaran 2018 FASEB J2018Rajasekaran R, Felser A, Nuoffer JM, Dufour JF, St-Pierre MV (2018) The histidine triad nucleotide-binding protein 2 (HINT-2) positively regulates hepatocellular energy metabolism. FASEB J 32:5143-61.MouseLiver
Hancock 2018 Elife2018Hancock M, Hafstad AD, Nabeebaccus AA, Catibog N, Logan A, Smyrnias I, Hansen SS, Lanner J, Schröder K, Murphy MP, Shah AM, Zhang M (2018) Myocardial NADPH oxidase-4 regulates the physiological response to acute exercise. Elife 7:e41044.MouseHeart
Bouwkamp 2018 Neurol Genet2018Bouwkamp CG, Afawi Z, Fattal-Valevski A, Krabbendam IE, Rivetti S, Masalha R, Quadri M, Breedveld GJ, Mandel H, Tailakh MA, Beverloo HB, Stevanin G, Brice A, van IJcken WFJ, Vernooij MW, Dolga AM, de Vrij FMS, Bonifati V, Kushner SA (2018) ACO2 homozygous missense mutation associated with complicated hereditary spastic paraplegia. Neurol Genet 4:e223.Human
Kamunde 2018 Free Radic Biol Med2018Kamunde C, Sharaf M, MacDonald N (2018) H2O2 metabolism in liver and heart mitochondria: Low emitting-high scavenging and high emitting-low scavenging systems. Free Radic Biol Med 124:135-48.FishesHeart
Liver
Stepanova 2018 J Neurochem2018Stepanova A, Konrad C, Manfredi G, Springett R, Ten V, Galkin A (2018) The dependence of brain mitochondria reactive oxygen species production on oxygen level is linear, except when inhibited by antimycin A. J Neurochem 148:731-45.MouseNervous system
Britto 2018 BMC Biol2018Britto FA, Cortade F, Belloum Y, Blaquière M, Gallot YS, Docquier A, Pagano AF, Jublanc E, Bendridi N, Koechlin-Ramonatxo C, Chabi B, Francaux M, Casas F, Freyssenet D, Rieusset J, Giorgetti-Peraldi S, Carnac G, Ollendorff V, Favier FB (2018) Glucocorticoid-dependent REDD1 expression reduces muscle metabolism to enable adaptation under energetic stress. BMC Biol 16:65.MouseSkeletal muscle
Havird 2018 bioRxiv2018Havird JC, Noe GR, Link L, Torres A, Logan DC, Sloan DB, Chicco AJ (2018) Assessing mitochondrial function in angiosperms with highly divergent mitochondrial genomes. bioRxiv doi: https://doi.org/10.1101/448902.Plants
Zhuang 2018 Thesis2018Zhuang Y (2018) Potential application of alternative oxidase (AOX) in neurodegenerative diseases. Master's Thesis p71.MouseNervous system
Kolb 2018 J Am Soc Nephrol2018Kolb AL, Corridon PR, Zhang S, Xu W, Witzmann FA, Collett JA, Rhodes GJ, Winfree S, Bready D, Pfeffenberger ZJ, Pomerantz JM, Hato T, Nagami GT, Molitoris BA, Basile DP, Atkinson SJ, Bacallao RL (2018) Exogenous gene transmission of isocitrate dehydrogenase 2 mimics ischemic preconditioning protection. J Am Soc Nephrol 29:1154-64.Kidney
Paech 2018b Toxicology2018Paech F, Abegg VF, Duthaler U, Terracciano L, Bouitbir J, Krähenbühl S (2018) Sunitinib induces hepatocyte mitochondrial damage and apoptosis in mice. Toxicology 409:13-23.MouseLiver
Kim 2018 Free Radic Biol Med2018Kim M, Stepanova A, Niatsetskaya Z, Sosunov S, Arndt S, Murphy MP, Galkin A, Ten VS (2018) Attenuation of oxidative damage by targeting mitochondrial complex I in neonatal hypoxic-ischemic brain injury. Free Radic Biol Med 124:517-24.MouseNervous system
Ortega-Dominguez 2017 Food Chem Toxicol2017Ortega-Domínguez B, Aparicio-Trejo OE, García-Arroyo FE, León-Contreras JC, Tapia E, Molina-Jijón E, Hernández-Pando R, Sánchez-Lozada LG, Barrera-Oviedo D, Pedraza-Chaverri J (2017) Curcumin prevents cisplatin-induced renal alterations in mitochondrial bioenergetics and dynamic. Food Chem Toxicol 107:373-85.
Mottahedin 2017 J Cereb Blood Flow Metab2017Mottahedin A, Svedin P, Nair S, Mohn CJ, Wang X, Hagberg H, Ek J, Mallard C (2017) Systemic activation of Toll-like receptor 2 suppresses mitochondrial respiration and exacerbates hypoxic-ischemic injury in the developing brain. J Cereb Blood Flow Metab 37:1192-8.MouseNervous system
Dixit 2017 Free Radic Biol Med2017Dixit S, Fessel JP, Harrison FE (2017) Mitochondrial dysfunction in the APP/PSEN1 mouse model of Alzheimer's disease and a novel protective role for ascorbate. Free Radic Biol Med 112:515-23.MouseHeart
Ferens 2017 Biochem Cell Biol2017Ferens FG, Spicer V, Krokhin OV, Motnenko A, Summers WA, Court DA (2017) A deletion variant partially complements a porin-less strain of Neurospora crassa. Biochem Cell Biol 95:318-27.Fungi
Teplova 2017 Toxicol Lett2017Teplova VV, Belosludtsev KN, Kruglov AG (2017) Mechanism of triclosan toxicity: Mitochondrial dysfunction including complex II inhibition, superoxide release and uncoupling of oxidative phosphorylation. Toxicol Lett 275:108-17.RatLiver
Menezes-Filho 2017 Free Radic Biol Med2017Menezes-Filho SL, Amigo I, Prado FM, Ferreira NC, Koike MK, Pinto IFD, Miyamoto S, Montero EFS, Medeiros MHG, Kowaltowski AJ (2017) Caloric restriction protects livers from ischemia/reperfusion damage by preventing Ca2+-induced mitochondrial permeability transition. Free Radic Biol Med 110:219-27.MouseLiver
Stepanova 2017 J Cereb Blood Flow Metab2017Stepanova A, Kahl A, Konrad C, Ten V, Starkov AS, Galkin A (2017) Reverse electron transfer results in a loss of flavin from mitochondrial complex I: Potential mechanism for brain ischemia reperfusion injury. J Cereb Blood Flow Metab 37:3649-58.MouseNervous system
Liu 2017 Physiol Rep2017Liu A, Philip J, Vinnakota KC, Van den Bergh F, Tabima DM, Hacker T, Beard DA, Chesler NC (2017) Estrogen maintains mitochondrial content and function in the right ventricle of rats with pulmonary hypertension. Physiol Rep 5:e13157.RatHeart
Lau 2017 Dissertation2017Lau G (2017) Adaptive variation of mitochondrial function in response to oxygen variability in intertidal sculpins (Cottidae, Actinopterygii). Dissertation p148.FishesNervous system
Du 2017 Evolution2017Du SNN, Khajali F, Dawson NJ, Scott GR (2017) Hybridization increases mitochondrial production of reactive oxygen species in sunfish. Evolution 71:1643-52.FishesLiver
Correa 2017 Crit Care2017Corrêa TD, Pereira AJ, Brandt S, Vuda M, Djafarzadeh S, Takala J, Jakob SM (2017) Time course of blood lactate levels, inflammation, and mitochondrial function in experimental sepsis. Crit Care 21:105.PigNervous system
Zhou 2017 Biochim Biophys Acta2017Zhou L, Wang W, Hoppel C, Liu J, Zhu X (2017) Parkinson's disease-associated pathogenic VPS35 mutation causes complex I deficits. Biochim Biophys Acta 1863:2791-5.HumanFibroblast
Ravasz 2017 Neurochem Int2017Ravasz D, Kacso G, Fodor V, Horvath K, Adam-Vizi V, Chinopoulos C (2017) Catabolism of GABA, succinic semialdehyde or gamma-hydroxybutyrate through the GABA shunt impair mitochondrial substrate-level phosphorylation. Neurochem Int 109:41-53.MouseNervous system
Liver
Cockova 2017 Thesis2017Čočková Z (2017) Modulation of RNA demethylase FTO function in SH-SY5Y cells: the effect on insulin signaling and mitochondrial respiration. Diploma Thesis p70.HumanNervous system
Asseburg 2017 Thesis2017Asseburg H (2017) Untersuchungen zur nutritiven Prävention der Neurodegeneration – Wirkungen von Trauben- und Olivenpolyphenolen auf die mitochondriale und kognitive Dysfunktion bei der Gehirnalterung und Alzheimer-Erkrankung. Dissertation p296.Mouse
Rat
Nervous system
Other cell lines
Porplycia 2017 Am J Physiol Regul Integr Comp Physiol2017Porplycia D, Lau GY, McDonald J, Chen Z, Richards JG, Moyes CD (2017) Subfunctionalization of COX4 paralogs in fish. Am J Physiol Regul Integr Comp Physiol 312:R671-R680.FishesSkeletal muscle
Lopez 2017 PLOS ONE2017López A, Ortiz F, Doerrier C, Venegas C, Fernández-Ortiz M, Aranda P, Díaz-Casado ME, Fernández-Gil B, Barriocanal-Casado E, Escames G, López L, Acuña-Castroviejo D (2017) Mitochondrial impairment and melatonin protection in parkinsonian mice do not depend of inducible or neuronal nitric oxide synthases. PLOS ONE 12:e0183090.Mouse
Duicu 2017 Can J Physiol Pharmacol2017Duicu OM, Privistirescu A, Wolf A, Petruş A, Dănilă MD, Raţiu CD, Muntean DM, Sturza A (2017) Methylene blue improves mitochondrial respiration and decreases oxidative stress in a substrate-dependent manner in diabetic rat hearts. Can J Physiol Pharmacol 95:1376-82.RatHeart
Fisar 2017 Indian J Biochem Biophys2017Fišar Z, Hroudová J, Namrata S, Macečková D, Kopřivová A (2017) Protocols for high-resolution respirometry experiments to test the activity of electron transfer system of pig brain mitochondria. Indian J Biochem Biophys 54:258-72.PigNervous system
Krishnathas 2017 Med Chem Comm2017Krishnathas R, Bonke E, Dröse S, Zickermann V, Nasiri HR (2017) Identification of 4-N-[2-(4-phenoxyphenyl)ethyl]quinazoline-4,6-diamine as a novel, highly potent and specific inhibitor of mitochondrial complex I. Med Chem Comm 8:657-61.RatHeart
Lalia 2017 Aging (Albany NY)2017Lalia AZ, Dasari S, Robinson MM, Abid H, Morse DM, Klaus KA, Lanza IR (2017) Influence of omega-3 fatty acids on skeletal muscle protein metabolism and mitochondrial bioenergetics in older adults. Aging (Albany NY) 9:1096-1129.HumanSkeletal muscle
Knuppertz 2017 Aging Cell2017Knuppertz L, Osiewacz HD (2017) Autophagy compensates impaired energy metabolism in CLPXP-deficient Podospora anserina strains and extends healthspan. Aging Cell 16:704-15.Fungi
Sharaf 2017 Biochim Biophys Acta2017Sharaf MS, Stevens D, Kamunde C (2017) Mitochondrial transition ROS spike (mTRS) results from coordinated activities of complex I and nicotinamide nucleotide transhydrogenase. Biochim Biophys Acta 1858:955-65.Mouse
Fishes
Heart
Liver
Briston 2017 Sci Rep2017Briston T, Roberts M, Lewis S, Powney B, M Staddon J, Szabadkai G, Duchen MR (2017) Mitochondrial permeability transition pore: sensitivity to opening and mechanistic dependence on substrate availability. Sci Rep 7:10492.RatLiver
Joergensen 2017 Physiol Rep2017Jørgensen W, Rud KA, Mortensen OH, Frandsen L, Grunnet N, Quistorff B (2017) Your mitochondria are what you eat: a high-fat or a high-sucrose diet eliminates metabolic flexibility in isolated mitochondria from rat skeletal muscle. Physiol Rep 5. pii: e13207.RatSkeletal muscle
Valis 2017 Oncotarget2017Vališ K, Grobárová V, Hernychová L, Bugáňová M4, Kavan D, Kalous M, Černý J, Stodůlková E, Kuzma M, Flieger M, Černý J, Novák P (2017) Reprogramming of leukemic cell metabolism through the naphthoquinonic compound Quambalarine B. Oncotarget 8:103137-53.RatLiver
Varga 2017 Inflammopharmacology2017Varga G, Ugocsai M, Hartmann P, Lajkó N, Molnár R, Szűcs S, Jász DK, Érces D, Ghyczy M, Tóth G, Boros M (2017) Acetylsalicylic acid-tris-hydroxymethyl-aminomethane reduces colon mucosal damage without causing gastric side effects in a rat model of colitis. Inflammopharmacology 26:261-71.RatLiver
Rekuviene 2017 Neurosci Lett2017Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Rotenone decreases ischemia-induced injury by inhibiting mitochondrial permeability transition in mature brains. Neurosci Lett 653:45-50.RatNervous system
Djordjevic 2017 Neuroscience2017Djordjevic J, Thomson E, Chowdhury SR, Snow WM, Perez C, Wong TP, Fernyhough P, Albensi BC (2017) Brain region- and sex-specific alterations in mitochondrial function and NF-κB signaling in the TgCRND8 mouse model of Alzheimer's disease. Neuroscience 361:81-92.MouseNervous system
Komlodi 2017 Neuropharmacology2017Komlódi T, Tretter L (2017) Methylene blue stimulates substrate-level phosphorylation catalysed by succinyl-CoA ligase in the citric acid cycle. Neuropharmacology 123:287-98.Guinea pigNervous system
Sivertsson 2017 Am J Physiol Renal Physiol2017Sivertsson E, Friederich-Persson M, Öberg CM, Fasching A, Hansell P, Rippe B, Palm F (2017) Inhibition of mammalian target of rapamycin decreases intrarenal oxygen availability and alters glomerular permeability. Am J Physiol Renal Physiol 314:F864-F872.RatKidney
Mathers 2017 J Comp Physiol B2017Mathers KE, McFarlane SV, Zhao L, Staples JF (2017) Regulation of mitochondrial metabolism during hibernation by reversible suppression of electron transport system enzymes. J Comp Physiol B 187:227-34.Other mammalsLiver
Gruenig 2017 Toxicol In Vitro2017Grünig D, Felser A, Bouitbir J, Krähenbühl S (2017) The catechol-O-methyltransferase inhibitors tolcapone and entacapone uncouple and inhibit the mitochondrial respiratory chain in HepaRG cells. Toxicol In Vitro 42:337-47.Human
Mouse
Liver
Heim 2017 Am J Physiol Regul Integr Comp Physiol2017Heim AB, Chung D, Florant GL, Chicco AJ (2017) Tissue-specific seasonal changes in mitochondrial function of a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 313:R180-90.Other mammalsHeart
Skeletal muscle
Liver
Fat
Robinson 2017 Cell Metabol2017Robinson MM, Dasari S, Konopka AR, Johnson ML, Manjunatha S, Esponda RR, Carter RE, Lanza IR, Nair KS (2017) Enhanced protein translation underlies improved metabolic and physical adaptations to different exercise training modes in young and old humans. Cell Metab 25:581-92.HumanSkeletal muscle
Wollenman 2017 PLOS ONE2017Wollenman LC, Vander Ploeg MR, Miller ML, Zhang Y, Bazil JN (2017) The effect of respiration buffer composition on mitochondrial metabolism and function. PLOS ONE 12:e0187523.Guinea pigHeart
Liver
Anderson 2017 Cell Metab2017Anderson KA, Huynh FK, Fisher-Wellman K, Stuart JD, Peterson BS, Douros JD, Wagner GR, Thompson JW, Madsen AS, Green MF, Sivley RM, Ilkayeva OR, Stevens RD, Backos DS, Capra JA, Olsen CA, Campbell JE, Muoio DM, Grimsrud PA, Hirschey MD (2017) SIRT4 is a lysine deacylase that controls leucine metabolism and insulin secretion. Cell Metab 25:838-55.MouseHeart
Liver
Selwood 2017 US Patent2017Selwood D, Baker D, Szabadkai G, Duchen MR, Hill JM, Warne JND (2017) Quinolium conjugates of cyclosporin . US Patent US20170349632 A1.MouseLiver
Sharaf 2017 Aquat Toxicol2017Sharaf MS, Stevens D, Kamunde C (2017) Zinc and calcium alter the relationship between mitochondrial respiration, ROS and membrane potential in rainbow trout (Oncorhynchus mykiss) liver mitochondria. Aquat Toxicol 189:170-83.FishesLiver
McFarlane 2017 Am J Physiol Regul Integr Comp Physiol2017McFarlane SV, Mathers KE, Staples JF (2017) Reversible temperature-dependent differences in brown adipose tissue respiration during torpor in a mammalian hibernator. Am J Physiol Regul Integr Comp Physiol 312:R434-42.Other mammalsFat
Kudin 2017 Int J Mol Sci2017Kudin AP, Mawasi H, Eisenkraft A, Elger CE, Bialer M, Kunz WS (2017) Mitochondrial liver toxicity of valproic acid and its acid derivatives is related to inhibition of α-lipoamide dehydrogenase. Int J Mol Sci 18. pii: E1912.RatNervous system
Liver
Djafarzadeh 2017 J Vis Exp2017Djafarzadeh S, Jakob SM (2017) High-resolution respirometry to assess mitochondrial function in permeabilized and intact cells. J Vis Exp 8.doi: 10.3791/54985..
Chung 2017 Sci Rep2017Chung DJ, Morrison PR, Bryant HJ, Jung E, Brauner CJ, Schulte PM (2017) Intraspecific variation and plasticity in mitochondrial oxygen binding affinity as a response to environmental temperature. Sci Rep 7:16238.FishesLiver
Fink 2017 Am J Physiol Cell Physiol2017Fink BD, Bai F, Yu L, Sivitz WI (2017) Regulation of ATP production: dependence on calcium concentration and respiratory state. Am J Physiol Cell Physiol 313:C146-53.MouseSkeletal muscle
Nemeth 2017 Thesis2017Németh B (2017) The effect of itaconic acid on mitochondrial substrate-level phosphorylation. PhD Thesis p84.MouseLiver
Schmidt 2017 J Vasc Surg2017Schmidt CA, Ryan TE, Lin CT, Inigo MM, Green TD, Brault JJ, Spangenburg EE, McClung JM (2017) Diminished force production and mitochondrial respiratory deficits are strain-dependent myopathies of subacute limb ischemia. J Vasc Surg 65:1504-1514.MouseSkeletal muscle
Singhal 2017 Mol Biol Cell2017Singhal RK, Kruse C, Heidler J, Strecker V, Zwicker K, Düsterwald L, Westermann B, Herrmann JM, Wittig I, Rapaport D (2017) Coi1 is a novel assembly factor of the yeast complex III-complex IV supercomplex. Mol Biol Cell [Epub ahead of print].Saccharomyces cerevisiae
Fink 2017 Pharmacol Res Perspect2017Fink BD, Guo DF, Kulkarni CA, Rahmouni K, Kerns RJ, Sivitz WI (2017) Metabolic effects of a mitochondrial-targeted coenzyme Q analog in high fat fed obese mice. Pharmacol Res Perspect 5:e00301.MouseLiver
Newsom 2017 Am J Physiol Endocrinol Metab2017Newsom SA, Miller BF, Hamilton KL, Ehrlicher SE, Stierwalt HD, Robinson MM (2017) Long-term rates of mitochondrial protein synthesis are increased in mouse skeletal muscle with high fat feeding regardless of insulin sensitizing treatment. Am J Physiol Endocrinol Metab 313:552-62.MouseSkeletal muscle
Abdurrachim 2017 Cardiovasc Res2017Abdurrachim D, Nabben M, Hoerr V, Kuhlmann MT, Bovenkamp P, Ciapaite J, Geraets IME, Coumans W, Luiken JJFP, Glatz JFC, Schäfers M, Nicolay K, Faber C, Hermann S, Prompers JJ (2017) Diabetic db/db mice do not develop heart failure upon pressure overload: a longitudinal in vivo PET, MRI, and MRS study on cardiac metabolic, structural, and functional adaptations. Cardiovasc Res 113:1148-60.MouseHeart
Wang 2017 Mol Cell2017Wang X, Auwerx J (2017) Systems phytohormone responses to mitochondrial proteotoxic stress. Mol Cell 68:540-51.Plants
Mitroshina 2017 Mod Technol Med2017Mitroshina ЕV, Abogessimengane BZ, Urazov МD, Hamraoui I, Mishchenko ТА, Astrakhanova ТА, Shchelchkova NА, Lapshin RD, Shishkina ТV, Belousova II, Mukhina IV, Vedunova МV (2017) Adaptive role of glial cell line-derived neurotrophic factor in cerebral ischemia. Mod Technol Med 9:68-76.MouseNervous system
Lau 2017 Mol Biol Evol2017Lau GY, Mandic M, Richards JG (2017) Evolution of cytochrome c oxidase in hypoxia tolerant Sculpins (Cottidae, Actinopterygii). Mol Biol Evol 34:2153-62.FishesNervous system
Sobotka 2017 Thesis2017Sobotka O (2017) Pharmacological and metabolic influence on liver mitochondrial functions. PhD Thesis p127.Mouse
Rat
Liver
Takahashi 2017 Exp Gerontol2017Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2017) Optic atrophy 1 mediates coenzyme Q-responsive regulation of respiratory complex IV activity in brain mitochondria. Exp Gerontol 98:217-223.MouseNervous system
Boutant 2017 EMBO J2017Boutant M, Kulkarni SS, Joffraud M, Ratajczak J, Valera-Alberni M, Combe R, Zorzano A, Cantó C (2017) Mfn2 is critical for brown adipose tissue thermogenic function. EMBO J 36:1543-58.MouseFat
Fibroblast
Rouet 2017 US Patent2017Rouet P, Smih F (2017) ApoO for use in method for treating cancer and various pathophysiological situations. US Patent US20170035842 A1.Human
Mouse
Heart
Liver
Da Silva 2017 Neurotox Res2017Da Silva JC, Amaral AU, Cecatto C, Wajner A, Dos Santos Godoy K, Ribeiro RT, de Mello Gonçalves A, Zanatta Â, da Rosa MS, Loureiro SO, Vargas CR, Leipnitz G, de Souza DOG, Wajner M (2017) α-Ketoadipic acid and α-aminoadipic acid cause disturbance of glutamatergic neurotransmission and induction of oxidative stress in vitro in brain of adolescent rats. Neurotox Res 32:276-90.RatNervous system
Rodrigues-Silva 2017 J Neurooncol2017Rodrigues-Silva E, Siqueira-Santos ES, Ruas JS, Ignarro RS, Figueira TR, Rogério F, Castilho RF (2017) Evaluation of mitochondrial respiratory function in highly glycolytic glioma cells reveals low ADP phosphorylation in relation to oxidative capacity. J Neurooncol 133:519-29.RatNervous system
Schatton 2017 J Cell Biol2017Schatton D, Pla-Martin D, Marx MC, Hansen H, Mourier A, Nemazanyy I, Pessia A, Zentis P, Corona T, Kondylis V, Barth E, Schauss AC, Velagapudi V, Rugarli EI (2017) CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol 216:675-93.MouseLiver
De Velasco 2017 Br J Nutr2017de Velasco PC, Chicaybam G, Ramos-Filho DM, Dos Santos RMAR, Mairink C, Sardinha FLC, El-Bacha T, Galina A, Tavares-do-Carmo MDG (2017) Maternal intake of trans-unsaturated or interesterified fatty acids during pregnancy and lactation modifies mitochondrial bioenergetics in the liver of adult offspring in mice. Br J Nutr 118:41-52.MouseLiver
Zhang 2017 J Am Heart Assoc2017Zhang X, Zhang Z, Zhao Y, Jiang N, Qiu J, Yang Y, Li J, Liang X, Wang X, Tse G, Li G, Liu T (2017) Alogliptin, a dipeptidyl peptidase-4 inhibitor, alleviates atrial remodeling and improves mitochondrial function and biogenesis in diabetic rabbits. J Am Heart Assoc 6:e005945.RabbitHeart
Mahalingam 2017 J Physiol2017Mahalingam S, McClelland GB, Scott GR (2017) Evolved changes in the intracellular distribution and physiology of muscle mitochondria in high-altitude native deer mice. J Physiol 595:4785-801.MouseSkeletal muscle
Cecatto 2017 Neurochem Int2017Cecatto C, Amaral AU, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Gonçalves AM, Vargas CR, Wajner M (2017) Mevalonolactone disrupts mitochondrial functions and induces permeability transition pore opening in rat brain mitochondria: Implications for the pathogenesis of mevalonic aciduria. Neurochem Int 108:133-45.RatNervous system
Liver
Linden 2017 Am J Physiol Gastrointest Liver Physiol2017Linden MA, Fletcher JA, Meers GM, Thyfault JP, Laughlin MH, Rector RS (2017) A return to ad libitum feeding following caloric restriction promotes hepatic steatosis in hyperphagic OLETF rats. Am J Physiol Gastrointest Liver Physiol 311:G387-95.RatLiver
Nabeebaccus 2017 JCI Insight2017Nabeebaccus AA, Zoccarato A, Hafstad AD, Santos CX, Aasum E, Brewer AC, Zhang M, Beretta M, Yin X, West JA, Schröder K, Griffin JL, Eykyn TR, Abel ED, Mayr M, Shah AM (2017) Nox4 reprograms cardiac substrate metabolism via protein O-GlcNAcylation to enhance stress adaptation. JCI Insight 2:96184.MouseHeart
Huang 2017 Sci Rep2017Huang L, Zhang K, Guo Y, Huang F, Yang K, Chen L, Huang K, Zhang F, Long Q, Yang Q (2017) Honokiol protects against doxorubicin cardiotoxicity via improving mitochondrial function in mouse hearts. Sci Rep 7:11989.MouseHeart
Campos 2017 Autophagy2017Campos JC, Queliconi BB, Bozi LHM, Bechara LRG, Dourado PMM, Andres AM, Jannig PR, Gomes KMS, Zambelli VO, Rocha-Resende C, Guatimosim S, Brum PC, Mochly-Rosen D, Gottlieb RA, Kowaltowski AJ, Ferreira JCB (2017) Exercise reestablishes autophagic flux and mitochondrial quality control in heart failure. Autophagy 13:1304-317.RatHeart
Rekuviene 2017 Data Brief2017Rekuviene E, Ivanoviene L, Borutaite V, Morkuniene R (2017) Data on effects of rotenone on calcium retention capacity, respiration and activities of respiratory chain complexes I and II in isolated rat brain mitochondria. Data Brief 13:707-12.RatNervous system
Calcutt 2017 J Clin Invest2017Calcutt NA, Smith DR, Frizzi K, Sabbir MG, Chowdhury SK, Mixcoatl-Zecuatl T, Saleh A, Muttalib N, Van der Ploeg R, Ochoa J, Gopaul A, Tessler L, Wess J, Jolivalt CG, Fernyhough P (2017) Selective antagonism of muscarinic receptors is neuroprotective in peripheral neuropathy. J Clin Invest 127:608-22.RatNervous system
Hu 2017 Proc Natl Acad Sci U S A2017Hu H, Nan J, Sun Y, Zhu D, Xiao C, Wang Y, Zhu L, Wu Y, Zhao J, Wu R, Chen J, Yu H, Hu X, Zhu W, Wang J (2017) Electron leak from NDUFA13 within mitochondrial complex I attenuates ischemia-reperfusion injury via dimerized STAT3. Proc Natl Acad Sci U S A 114:11908-13.Mouse
Kiprowska 2017 Biochim Biophys Acta2017Kiprowska MJ, Stepanova A, Todaro DR, Galkin A, Haas A, Wilson SM, Figueiredo-Pereira ME (2017) Neurotoxic mechanisms by which the USP14 inhibitor IU1 depletes ubiquitinated proteins and Tau in rat cerebral cortical neurons: Relevance to Alzheimer's disease. Biochim Biophys Acta 1863:1157-70.RatNervous system
Koning 2017 J Cereb Blood Flow Metab2017Koning G, Leverin AL, Nair S, Schwendimann L, Ek J, Carlsson Y, Gressens P, Thornton C, Wang X*, Mallard C, Hagberg H (2017) Magnesium induces preconditioning of the neonatal brain via profound mitochondrial protection. J Cereb Blood Flow Metab [Epub ahead of print].Rat
De Carvalho 2017 Toxicol Research2017de Carvalho NR, Rodrigues NR, Macedo GE, Boligon AA, de Campos MM, Posser T, Cunha FAB, Coutinho HD, Klamt F, Bristot IJ, Merritt TJS, Franco JL (2017) Eugenia uniflora leaves essential oil promotes mitochondrial dysfunction in Drosophila melanogaster through the inhibition of oxidative phosphorylation. Toxicol Research 6:526-34 .Drosophila
Xu 2017 Free Radic Biol Med2017Xu J, Bian X, Liu Y, Hong L, Teng T, Sun Y, Xu Z (2017) Adenosine A2 receptor activation ameliorates mitochondrial oxidative stress upon reperfusion through the posttranslational modification of NDUFV2 subunit of complex I in the heart. Free Radic Biol Med 106:208-18.RatHeart
Pecinova 2017 Oxid Med Cell Longev2017Pecinova A, Drahota Z, Kovalcikova J, Kovarova N, Pecina P, Alan L, Zima M, Houstek J, Mracek T (2017) Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production. Oxid Med Cell Longev 7038603.RatFat
Garcia-Neto 2017 PLOS ONE2017Garcia-Neto W, Cabrera-Orefice A, Uribe-Carvajal S, Kowaltowski AJ, Alberto Luévano-Martínez L (2017) High osmolarity environments activate the mitochondrial alternative oxidase in Debaryomyces Hansenii. PLOS ONE 12:e0169621.Fungi
Perks 2017 Sci Adv2017Perks KL, Ferreira N, Richman TR, Ermer JA, Kuznetsova I, Shearwood AJ, Lee RG, Viola HM, Johnstone VPA, Matthews V, Hool LC, Rackham O, Filipovska A (2017) Adult-onset obesity is triggered by impaired mitochondrial gene expression. Sci Adv 3:e1700677.MouseHeart
Liver
Derungs 2017 Mol Psychiatry2017Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14.MouseNervous system
Gonzalez-Durruthy 2017 Nanomaterials (Basel)2017González-Durruthy M, Monserrat JM, Rasulev B, Casañola-Martín GM, Barreiro Sorrivas JM, Paraíso-Medina S, Maojo V, González-Díaz H, Pazos A, Munteanu CR (2017) Carbon nanotubes' effect on mitochondrial oxygen flux dynamics: polarography experimental study and machine learning models using star graph trace invariants of raman spectra. Nanomaterials (Basel) 7. pii: E386.RatLiver
Jahandiez 2017 Basic Res Cardiol2017Jahandiez V, Cour M, Bochaton T, Abrial M, Loufouat J, Gharib A, Varennes A, Ovize M, Argaud L (2017) Fast therapeutic hypothermia prevents post-cardiac arrest syndrome through cyclophilin D-mediated mitochondrial permeability transition inhibition. Basic Res Cardiol 112:35.RabbitHeart
Nervous system
Gusdon 2017 Exp Gerontol2017Gusdon AM, Callio J, Distefano G, O'Doherty RM, Goodpaster BH, Coen PM, Chu CT (2017) Exercise increases mitochondrial complex I activity and DRP1 expression in the brains of aged mice. Exp Gerontol 90:1-13.MouseNervous system
Djafarzadeh 2017b J Vis Exp2017Djafarzadeh S, Jakob SM (2017) Isolation of intact mitochondria from skeletal muscle by differential centrifugation for High-Resolution Respirometry measurements. J Vis Exp doi: 10.3791/55251.Skeletal muscle
Honrath 2017 Cell Death Differ2017Honrath B, Matschke L, Meyer T, Magerhans L, Perocchi F, Ganjam GK, Zischka H, Krasel C, Gerding A, Bakker BM, Bünemann M, Strack S, Decher N, Culmsee C, Dolga AM (2017) SK2 channels regulate mitochondrial respiration and mitochondrial Ca2+ uptake. Cell Death Differ 24:761-73.MouseNervous system
Other cell lines
Shuvo 2017 Can J Microbiol2017Shuvo SR, Kovaltchouk U, Zubaer A, Kumar A, Summers WAT, Donald LJ, Hausner G, Court DA (2017) Functional characterization of an N-terminally-truncated mitochondrial porin expressed in Neurospora crassa. Can J Microbiol 17:1-9.Fungi
Pravenec 2017 Physiol Res2017Pravenec M1, Zídek V, Landa V, Mlejnek P, Šilhavý J, Šimáková M, Trnovská J, Škop V, Marková I, Malínská H, Hüttl M, Kazdová L, Bardová K, Tauchmannová K, Vrbacký M, Nůsková H, Mráček T, Kopecký J, Houštěk J (2017) Mutant Wars2 gene in spontaneously hypertensive rats impairs brown adipose tissue function and predisposes to visceral obesity. Physiol Res 66:917-24.RatEndothelial;epithelial;mesothelial cell
Fibroblast
MiPNet21.13 Comparison mt-preparations2016-10-18
O2k-Protocols
O2k-Protocols: Mitochondrial preparations for HRR.
MouseHeart
MiPNet14.05 TPP-mtMembranePotential2016-04-01
O2k-Protocols contents
TPP+ and mt-membrane potential.
MouseNervous system
Cagnone 2016 Sci Rep2016Cagnone GL, Tsai TS, Makanji Y, Matthews P, Gould J, Bonkowski MS, Elgass KD, Wong AS, Wu LE, McKenzie M, Sinclair DA, John JC (2016) Restoration of normal embryogenesis by mitochondrial supplementation in pig oocytes exhibiting mitochondrial DNA deficiency. Sci Rep 6:23229.PigGenital
Pambianco 2016 Cell Rep2016Pambianco S, Giovarelli M, Perrotta C, Zecchini S, Cervia D3, Di Renzo I, Moscheni C, Ripolone M, Violano R, Moggio M, Bassi MT, Puri PL, Latella L, Clementi E, De Palma C (2016) Reversal of defective mitochondrial biogenesis in limb-girdle muscular dystrophy 2D by independent modulation of histone and PGC-1α acetylation. Cell Rep 17:3010-23.MouseSkeletal muscle
Ryan 2016 J Mol Cell Cardiol2016Ryan TE, Schmidt CA, Alleman RJ, Tsang AM, Green TD, Neufer PD, Brown DA, McClung JM (2016) Mitochondrial therapy improves limb perfusion and myopathy following hindlimb ischemia. J Mol Cell Cardiol 97:191-6.MouseSkeletal muscle
Camacho-Pereira 2016 Cell Metab2016Camacho-Pereira J, Tarragó MG, Chini CC, Nin V, Escande C, Warner GM, Puranik AS, Schoon RA, Reid JM, Galina A, Chini EN (2016) CD38 dictates age-related NAD decline and mitochondrial dysfunction through an SIRT3-dependent mechanism. Cell Metab 23:1127-39.Human
Mouse
Liver
Lung;gill
Other cell lines
Galli 2016 Am J Physiol Regul Integr Comp Physiol2016Galli GL, Crossley J, Elsey RM, Dzialowski EM, Shiels HA, Crossley DA 2nd (2016) Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis. Am J Physiol Regul Integr Comp Physiol 311:R1164-72.ReptilesHeart
Levchenko 2016 Biochim Biophys Acta2016Levchenko M, Wuttke JM, Römpler K, Schmidt B, Neifer K, Juris L, Wissel M, Rehling P, Deckers M (2016) Cox26 is a novel stoichiometric subunit of the yeast cytochrome c oxidase. Biochim Biophys Acta 1863:1624-32.Saccharomyces cerevisiae
Cecatto 2016 Thesis2016Cecatto C (2016) Efeitos de acidos graxos hidroxilados de cadeia longa acumulados nas deficiencias da 3-hidroxiacil CoA desidrogenase de cadeia longa e da proteina trifunctional mitocondrial sobre a homeostase energetica mitochondrial nos musculos cardiaco e esqueletico de ratos jovens. Dissertation p103.RatHeart
Skeletal muscle
Berressem 2016 PLOS ONE2016Berressem D, Koch K, Franke N, Klein J, Eckert GP (2016) Intravenous treatment with a long-chain omega-3 lipid emulsion provides neuroprotection in a murine model of ischemic stroke - a pilot study. PLOS ONE 11:e0167329.MouseNervous system
Moon 2016 J Biol Chem2016Moon SH, Mancuso DJ, Sims HF, Liu X, Nguyen AL, Yang K, Guan S, Dilthey BG, Jenkins CM, Weinheimer CJ, Kovacs A, Abendschein D, Gross RW (2016) Cardiac myocyte-specific knock-out of calcium-independent phospholipase A2γ (iPLA2γ) decreases oxidized fatty acids during ischemia/reperfusion and reduces infarct size. J Biol Chem 291:19687-700.MouseHeart
Zinner 2016 Front Physiol2016Zinner C, Morales-Alamo D, Ørtenblad N, Larsen FJ, Schiffer TA, Willis SJ, Gelabert-Rebato M, Perez-Valera M, Boushel R, Calbet JA, Holmberg HC (2016) The physiological mechanisms of performance enhancement with sprint interval training fiffer between the upper and lower extremities in humans. Front Physiol 7:426.HumanSkeletal muscle
Chabi 2016 Exp Gerontol2016Chabi B, Pauly M, Carillon J, Carnac G, Favier FB, Fouret G, Bonafos B, Vanterpool F, Vernus B, Coudray C, Feillet-Coudray C, Bonnieu Z, Lacan D, Koechlin-Ramonatxo C (2016) Protective effect of myostatin gene deletion on aging-related muscle metabolic decline. Exp Gerontol 78:23-31.MouseSkeletal muscle
Robertson 2016 J Bioenerg Biomembr2016Robertson A, Schaltz K, Neimanis K, Staples JF, McDonald AE (2016) Heterologous expression of the Crassostrea gigas (Pacific oyster) alternative oxidase in the yeast Saccharomyces cerevisiae. J Bioenerg Biomembr 48:509-20.Saccharomyces cerevisiae
Munro 2016 Free Radic Biol Med2016Munro D, Banh S, Sotiri E, Tamanna N, Treberg JR (2016) The thioredoxin and glutathione-dependent H2O2 consumption pathways in muscle mitochondria: Involvement in H2O2 metabolism and consequence to H2O2 efflux assays. Free Radic Biol Med 96:334-46.RatSkeletal muscle
Scott 2016 Thesis2016Scott KY (2016) Evaluation of cardiac mitochondrial function in the fructose-fed rat. Master's Thesis p98.RatHeart
Sobotka 2016 J Bioenerg Biomembr2016Sobotka O, Endlicher R, Drahota Z, Kučera O, Rychtrmoc D, Raad M, Hakeem K, Červinková Z (2016) Impaired mitochondrial functions contribute to 3-bromopyruvate toxicity in primary rat and mouse hepatocytes. J Bioenerg Biomembr 48:363-73.Mouse
Rat
Liver
Li 2016 Neurochem Int2016Li H, Liu Y, Lin LT, Wang XR, Du SQ, Yan CQ, He T, Yang JW, Liu CZ (2016) Acupuncture reversed hippocampal mitochondrial dysfunction in vascular dementia rats. Neurochem Int 92:35-42.RatNervous system
Fink 2016 Am J Physiol Regul Integr Comp Physiol2016Fink BD, Bai F, Yu L, Sivitz WI (2016) Impaired utilization of membrane potential by complex II-energized mitochondria of obese, diabetic mice assessed using ADP recycling methodology. Am J Physiol Regul Integr Comp Physiol 311:756-63.MouseSkeletal muscle
Strecker 2016 Biochim Biophys Acta2016Strecker V, Kadeer Z, Heidler J, Cruciat CM, Angerer H, Giese H, Pfeiffer K, Stuart RA, Wittig I (2016) Supercomplex-associated Cox26 protein binds to cytochrome c oxidase. Biochim Biophys Acta 1863:1643-52.Saccharomyces cerevisiae
Vinnakota 2016a Biophys J2016Vinnakota KC, Bazil JN, Van den Bergh F, Wiseman RW, Beard DA (2016) Feedback regulation and time hierarchy of oxidative phosphorylation in cardiac mitochondria. Biophys J 110:972-80.RatHeart
Bareth 2016 Mol Biol Cell2016Bareth B, Nikolov M, Lorenzi I, Hildenbeutel M, Mick DU, Helbig C, Urlaub Z, Ott M, Rehling P, Dennerlein S (2016) Oms1 associates with cytochrome c oxidase assembly intermediates to stabilize newly synthesized Cox1. Mol Biol Cell 27:1570-80.Saccharomyces cerevisiae
Lark 2016 Am J Physiol Cell Physiol2016Lark DS, Torres MJ, Lin CT, Ryan TE, Anderson EJ, Neufer PD (2016) Direct real-time quantification of mitochondrial oxidative phosphorylation efficiency in permeabilized skeletal muscle myofibers. Am J Physiol Cell Physiol 311:C239-45.MouseSkeletal muscle
Richman 2016 Nat Commun2016Richman TR, Spåhr H, Ermer JA, Davies SM, Viola HM, Bates KA, Papadimitriou J, Hool LC, Rodger J, Larsson NG, Rackham O, Filipovska A (2016) Loss of the RNA-binding protein TACO1 causes late-onset mitochondrial dysfunction in mice. Nat Commun 7:11884.MouseHeart
Liver
Smith 2016 Diabetes2016Smith BK, Ford RJ, Desjardins EM, Green AE, Hughes MC, Houde VP, Day EA, Marcinko K, Crane JD, Mottillo EP, Perry CG, Kemp BE, Tarnopolsky MA, Steinberg GR (2016) Salsalate (Salicylate) uncouples mitochondria, improves glucose homeostasis, and reduces liver lipids independent of AMPK β1. Diabetes 65:3352-61.MouseFat
Liver
Skeletal muscle
Pravenec 2016 Physiol Genomics2016Pravenec M, Mlejnek P, Zídek V, Landa V, Šimáková M, Šilhavý J, Strnad H, Eigner S, Eigner Henke K, Škop V, Malínská H, Trnovská J, Kazdová L, Drahota Z, Mráček T, Houštěk J (2016) Autocrine effects of transgenic resistin reduce palmitate and glucose oxidation in brown adipose tissue. Physiol Genomics 48:420-7.RatFat
Renner 2016 Mycotoxin Res2016Renner L, Kahlert S, Tesch T, Bannert E, Frahm J, Barta-Böszörményi A, Kluess J, Kersten S, Schönfeld P, Rothkötter HJ, Dänicke S (2016) Chronic DON exposure and acute LPS challenge: effects on porcine liver morphology and function. Mycotoxin Res 33:207-18.PigLiver
Cecatto 2016 Toxicol In Vitro2016Cecatto C, Godoy KD, da Silva JC, Amaral AU, Wajner M (2016) Disturbance of mitochondrial functions provoked by the major long-chain 3-hydroxylated fatty acids accumulating in MTP and LCHAD deficiencies in skeletal muscle. Toxicol In Vitro 36:1-9.RatHeart
Skeletal muscle
Morton 2016 Nat Med2016Morton NM, Beltram J, Carter RN, Michailidou Z, Gorjanc G, McFadden C, Barrios-Llerena ME, Rodriguez-Cuenca S, Gibbins MT, Aird RE, Moreno-Navarrete JM, Munger SC, Svenson KL, Gastaldello A, Ramage L, Naredo G, Zeyda M, Wang ZV, Howie AF, Saari A, Sipilä P, Stulnig TM, Gudnason V, Kenyon CJ, Seckl JR, Walker BR, Webster SP, Dunbar DR, Churchill GA, Vidal-Puig A, Fernandez-Real JM, Emilsson V, Horvat S (2016) Genetic identification of thiosulfate sulfurtransferase as an adipocyte-expressed antidiabetic target in mice selected for leanness. Nat Med 22:771-9.MouseLiver
Shirey 2016 Biochemistry2016Shirey K, Stover KR, Cleary J, Hoang N, Hosler J (2016) Membrane-anchored cyclic peptides as effectors of mitochondrial oxidative phosphorylation. Biochemistry 55:2100-11.RatHeart
Liver
Larsen 2016 FASEB J2016Larsen FJ, Schiffer TA, Ørtenblad N, Zinner C, Morales-Alamo D, Willis SJ, Calbet JA, Holmberg HC, Boushel R (2016) High-intensity sprint training inhibits mitochondrial respiration through aconitase inactivation. FASEB J 30:417-27.HumanSkeletal muscle
Alleman 2016 Am J Physiol Heart Circ Physiol2016Alleman RJ, Tsang AM, Ryan TE, Patteson DJ, McClung JM, Spangenburg EE, Shaikh SR, Neufer PD, Brown DA (2016) Exercise-induced protection against reperfusion arrhythmia involves stabilization of mitochondrial energetics. Am J Physiol Heart Circ Physiol 310:H1360-70.RatHeart
Chorner 2016 Am J Physiol Regul Integr Comp Physiol2016Chorner Z, Barbeau PA, Castellani L, Wright DC, Chabowski A, Holloway GP (2016) Dietary α-linolenic acid supplementation alters skeletal muscle plasma membrane lipid composition, sarcolemmal FAT/CD36 abundance, and palmitate transport rates. Am J Physiol Regul Integr Comp Physiol 311:R1234-42.RatSkeletal muscle
Bai 2016 PLOS ONE2016Bai F, Fink BD, Yu L, Sivitz WI (2016) Voltage-dependent regulation of Complex II energized mitochondrial oxygen flux. PLOS ONE 11:e0154982.MouseHeart
Skeletal muscle
Nervous system
Liver
Kancirova 2016 Physiol Res2016Kancirová I, Jašová M, Muráriková M, Sumbalová Z, Uličná O, Ravingerová T, Waczulíková I, Ziegelhöffer A, Ferko M (2016) Cardioprotection induced by remote ischemic preconditioning preserves the mitochondrial respiratory function in acute diabetic myocardium. Physiol Res 65:S611-19.RatHeart
Chowdhury 2015 Biosci Rep2016Chowdhury SK, Djordjevic J, Albensi B, Fernyhough P (2015) Simultaneous evaluation of substrate-dependent oxygen consumption rates and mitochondrial membrane potential by TMRM and safranin in cortical mitochondria. Biosci Rep 36:e00286.MouseNervous system
Ojuka 2016 Am J Physiol Endocrinol Metab2016Ojuka E, Andrew B, Bezuidenhout N, George S, Maarman G, Madlala HP, Mendham A, Osiki PO (2016) Measurement of β-oxidation capacity of biological samples by respirometry: a review of principles and substrates. Am J Physiol Endocrinol Metab 310:E715-23.Human
Mouse
Rat
Skeletal muscle
Liver
Lalia 2016 J Clin Endocrinol Metab2016Lalia AZ, Dasari S, Johnson ML, Robinson MM, Konopka AR, Distelmaier K, Port JD, Glavin MT, Esponda RR, Nair KS, Lanza IR (2016) Predictors of whole-body insulin sensitivity across ages and adiposity in adult humans. J Clin Endocrinol Metab 101:626-34.HumanSkeletal muscle
Chen 2016 Nat Chem Biol2016Chen YJ, Mahieu NG, Huang X, Singh M, Crawford PA, Johnson SL, Gross RW, Schaefer J, Patti GJ (2016) Lactate metabolism is associated with mammalian mitochondria. Nat Chem Biol 12:937-43.HumanHeLa
Vinnakota 2016b Biophys J2016Vinnakota KC, Singhal A, Van den Bergh F, Bagher-Oskouei M, Wiseman RW, Beard DA (2016) Open-loop control of oxidative phosphorylation in skeletal and cardiac muscle mitochondria by Ca2+. Biophys J 110:954-61.RatHeart
Skeletal muscle
Viola 2016 J Physiol2016Viola H, Johnstone V, Szappanos HC, Richman T, Tsoutsman T, Filipovska A, Semsarian C, Hool L (2016) The L-type Ca2+ channel facilitates abnormal metabolic activity in the cTnI-G203S mouse model of hypertrophic cardiomyopathy. J Physiol 594:4051-70.MouseHeart
Queliconi 2016 PLOS ONE2016Queliconi BB, Kowaltowski AJ, Gottlieb RA (2016) Bicarbonate increases ischemia-reperfusion damage by inhibiting mitophagy. PLOS ONE 11:e0167678.RatHeart
Fisar 2016b Folia Biol (Praha)2016Fisar Z, Hroudova J, Singh N, Koprivova A, Maceckova D (2016) Effect of simvastatin, coenzyme Q10, resveratrol, acetylcysteine and acetylcarnitine on mitochondrial respiration. Folia Biol (Praha) 62:53-66.PigNervous system
Gomez 2016 Thesis2016Gomez CR (2016) Mitochondrial responses to anoxia exposure in red eared sliders (Trachemys scripta). Master's Thesis p102.ReptilesHeart
Nervous system
Kancirova 2016 Nove Strategicke Pristupy v experimentalnej Kardioprotekcii2016Kancirová I, Jašová M (2016) Mitochondrie ako hlavné efektory mechanizmov endogénnej ochrany myokardu. Nove Strategicke Pristupy v experimentalnej Kardioprotekcii 72-89.RatHeart
Heim 2016 Thesis2016Heim A (2016) Tissue-specific seasonal changes in mitochondrial respiratory function and membrane composition in the golden-matled ground squirrel. Master's Thesis p77.Other mammalsHeart
Skeletal muscle
Liver
Fat
Sparks 2016 Diabetologia2016Sparks LM, Gemmink A, Phielix E, Bosma M, Schaart G, Moonen-Kornips E, Jörgensen JA, Nascimento EB, Hesselink MK, Schrauwen P, Hoeks J (2016) ANT1-mediated fatty acid-induced uncoupling as a target for improving myocellular insulin sensitivity. Diabetologia 59:1030-9.Human
Mouse
Rat
Skeletal muscle
Other cell lines
Valenzuela 2016 Cell Death Dis2016Valenzuela R, Costa-Besada MA, Iglesias-Gonzalez J, Perez-Costas E, Villar-Cheda B, Garrido-Gil P, Melendez-Ferro M, Soto-Otero R, Lanciego JL, Henrion D, Franco R, Labandeira-Garcia JL (2016) Mitochondrial angiotensin receptors in dopaminergic neurons. Role in cell protection and aging-related vulnerability to neurodegeneration. Cell Death Dis 7:e2427.Mouse
Rat
Nervous system
Briston 2016 Sci Rep2016Briston T, Lewis S, Koglin M, Mistry K, Shen Y, Hartopp N, Katsumata R, Fukumoto H, Duchen MR, Szabadkai G, Staddon JM, Roberts M, Powney B (2016) Identification of ER-000444793, a Cyclophilin D-independent inhibitor of mitochondrial permeability transition, using a high-throughput screen in cryopreserved mitochondria. Sci Rep 6:37798.RatLiver
Iglesias-Gonzalez 2016 Mol Neurobiol2016Iglesias-González J, Sánchez-Iglesias S, Beiras-Iglesias A, Méndez-Álvarez E, Soto-Otero R (2016) Effects of aluminium on rat brain mitochondria bioenergetics: an in vitro and in vivo study. Mol Neurobiol 54:563-70.RatNervous system
Ryan 2016 Diabetes2016Ryan TE, Schmidt CA, Green TD, Spangenburg EE, Neufer PD, McClung JM (2016) Targeted expression of catalase to mitochondria protects against ischemic myopathy in high fat fed mice. Diabetes 65:2553-68.MouseSkeletal muscle
Kacso 2016 Biochem J2016Kacso G, Ravasz D, Doczi J, Németh B, Madgar O, Saada A, Ilin P, Miller C, Ostergaard E, Iordanov I, Adams D, Vargedo Z, Araki M, Araki K, Nakahara M, Ito H, Gál A, Molnár MJ, Nagy Z, Patocs A, Adam-Vizi V, Chinopoulos C (2016) Two transgenic mouse models for β-subunit components of succinate-CoA ligase yielding pleiotropic metabolic alterations. Biochem J 473:3463-85.MouseHeart
Nervous system
Liver
Amaral 2016 J Neurochem2016Amaral AU, Cecatto C, Castilho RF, Wajner M (2016) 2-methylcitric acid impairs glutamate metabolism and induces permeability transition in brain mitochondria. J Neurochem 137:62-75.RatNervous system
Asseburg 2016 Neuromolecular Med2016Asseburg H, Schäfer C, Müller M, Hagl S, Pohland M, Berressem D, Borchiellini M, Plank C, Eckert GP (2016) Effects of grape skin extract on age-related mitochondrial dysfunction, memory and life span in C57BL/6J mice. Neuromolecular Med 18:378-95.MouseNervous system
Ruas 2016 PLOS ONE2016Ruas JS, Siqueira-Santos ES, Amigo I, Rodrigues-Silva E, Kowaltowski AJ, Castilho RF (2016) Underestimation of the maximal capacity of the mitochondrial electron transport system in oligomycin-treated cells. PLOS ONE 11:e0150967.Human
Rat
Nervous system
Genital
Other cell lines
Mickevicius 2016 Thesis2016Mickevicius L (2016) Effect of short time ischemia/reperfusion in vivo on rat kidney mitochondria oxidative phosphorylation. Diploma Thesis p38.RatKidney
Radovic 2016 Diabetologia2016Radović B, Vujić N, Leopold C, Schlager S, Goeritzer M, Patankar JV, Korbelius M, Kolb D, Reindl J, Wegscheider M, Tomin T, Birner-Gruenberger R, Schittmayer M, Groschner L, Magnes C, Diwoky C, Frank S, Steyrer E, Du H, Graier WF, Madl T, Kratky D (2016) Lysosomal acid lipase regulates VLDL synthesis and insulin sensitivity in mice. Diabetologia 59:1743-52.MouseLiver
Moore 2016 Cryobiology2016Moore DS, Hand SC (2016) Cryopreservation of lipid bilayers by LEA proteins from Artemia franciscana and trehalose. Cryobiology 73:240-7.RatLiver
Strifler 2016 PLOS ONE2016Strifler G, Tuboly E, Szél E, Kaszonyi E, Cao C, Kaszaki J, Mészáros A, Boros M, Hartmann P (2016) Inhaled methane limits the mitochondrial electron transport chain dysfunction during experimental liver ischemia-reperfusion injury. PLOS ONE 11:e0146363.RatLiver
Roempler 2016 J Biol Chem2016Römpler K, Müller T, Juris L, Wissel M, Vukotic M, Hofmann K, Deckers M (2016) Overlapping role of respiratory supercomplex factor Rcf2 and its N-terminal homolog Rcf3 in Saccharomyces cerevisiae. J Biol Chem 291:23769-78.Saccharomyces cerevisiae
Bombicino 2016 Arch Biochem Biophys2016Bombicino SS, Iglesias DE, Zaobornyj T, Boveris A, Valdez LB (2016) Mitochondrial nitric oxide production supported by reverse electron transfer. Arch Biochem Biophys 607:8-19.RatHeart
Fisar 2016a Folia Biol (Praha)2016Fisar Z, Hroudova J (2016) Pig brain mitochondria as a biological model for study of mitochondrial respiration. Folia Biol (Praha) 62:15-25.PigNervous system
Koncsos 2016 Am J Physiol Heart Circ Physiol2016Koncsos G, Varga ZV, Baranyai T, Boengler K, Rohrbach S, Li L, Schlüter KD, Schreckenberg R, Radovits T, Oláh A, Mátyás C, Lux Á, Al-Khrasani M, Komlódi T, Bukosza N, Máthé D, Deres L, Barteková M, Rajtík T, Adameová A, Szigeti K, Hamar P, Helyes Z, Tretter L, Pacher P, Merkely B, Giricz Z, Schulz R, Ferdinandy P (2016) Diastolic dysfunction in prediabetic male rats: role of mitochondrial oxidative stress. Am J Physiol Heart Circ Physiol 311:H927-43.RatHeart
Thomas 2016 Neurodegeneration Therapeutics2016Thomas RR, Keeney PM, Berr SB, Khan SM, Portell FR, Shakenov MZ, Antkowiak PF, Kundu B, Tustison N, Brohawn DG, Bennett JP (2016) Recombinant human TFAM stimulates rat brain, rat cervical spinal cord and human neural stem cell mitochondrial bioenergetics. Neurodegeneration Therapeutics p41.RatNervous system
Eisenberg 2016 Nat Med2016Eisenberg T, Abdellatif M, Schroeder S, Primessnig U, Stekovic S, Pendl T, Harger A, Schipke J, Zimmermann A, Schmidt A, Tong M, Ruckenstuhl C, Dammbrueck C, Gross AS, Herbst V, Magnes C, Trausinger G, Narath S, Meinitzer A, Hu Z, Kirsch A, Eller K, Carmona-Gutierrez D, Büttner S, Pietrocola F, Knittelfelder O, Schrepfer E, Rockenfeller P, Simonini C, Rahn A, Horsch M, Moreth K, Beckers J, Fuchs H, Gailus-Durner V, Neff F, Janik D, Rathkolb B, Rozman J, de Angelis MH, Moustafa T, Haemmerle G, Mayr M, Willeit P, von Frieling-Salewsky M, Pieske B, Scorrano L, Pieber T, Pechlaner R, Willeit J, Sigrist SJ, Linke WA, Mühlfeld C, Sadoshima J, Dengjel J, Kiechl S, Kroemer G, Sedej S, Madeo F (2016) Cardioprotection and lifespan extension by the natural polyamine spermidine. Nat Med 22:1428-38.MouseHeart
Johnson 2016 Diabetes2016Johnson ML, Distelmaier K, Lanza IR, Irving BA, Robinson MM, Konopka AR, Shulman GI, Nair KS (2016) Mechanism by which caloric restriction improves insulin sensitivity in sedentary obese adults. Diabetes 65:74-84.HumanSkeletal muscle
Hamilton 2016 Physiol Rep2016Hamilton DJ, Minze LJ, Kumar T, Cao TN, Lyon CJ, Geiger PC, Hsueh WA, Gupte AA (2016) Estrogen receptor alpha activation enhances mitochondrial function and systemic metabolism in high-fat-fed ovariectomized mice. Physiol Rep 4. pii: e12913.MouseHeart
Reijne 2016 PLOS ONE2016Reijne AC, Ciapaite J, van Dijk TH, Havinga R, van der Zee EA, Groen AK, Reijngoud DJ, Bakker BM, van Dijk G (2016) Whole-body vibration partially reverses aging-induced increases in visceral adiposity and hepatic lipid storage in mice. PLOS ONE 11:e0149419.MouseSkeletal muscle
Liver
Szczepanowska 2016 EMBO J2016Szczepanowska K, Maiti P, Kukat A, Hofsetz E, Nolte H, Senft K, Becker C, Ruzzenente B, Hornig-Do HT, Wibom R, Wiesner RJ, Krüger M, Trifunovic A (2016) CLPP coordinates mitoribosomal assembly through the regulation of ERAL1 levels. EMBO J 35:2566-83.MouseHeart
Van Eunen 2016 BMC Biol2016van Eunen K, Volker-Touw CM, Gerding A, Bleeker A, Wolters JC, van Rijt WJ, Martines AM, Niezen-Koning KE, Heiner RM, Permentier H, Groen AK, Reijngoud DJ, Derks TG, Bakker BM (2016) Living on the edge: substrate competition explains loss of robustness in mitochondrial fatty-acid oxidation disorders. BMC Biol 14:107.MouseLiver
Amaral 2016 Biochim Biophys Acta2016Amaral AU, Cecatto C, da Silva JC, Wajner A, Godoy KD, Ribeiro RT, Wajner M (2016) cis-4-Decenoic and decanoic acids impair mitochondrial energy, redox and Ca2+ homeostasis and induce mitochondrial permeability transition pore opening in rat brain and liver: Possible implications for the pathogenesis of MCAD deficiency. Biochim Biophys Acta 1857:1363-72.RatNervous system
Liver
Zelenka 2016 Oxid Med Cell Longev2016Zelenka J, Dvořák A, Alán L, Zadinová M, Haluzík M, Vítek L (2016) Hyperbilirubinemia protects against aging-associated inflammation and metabolic deterioration. Oxid Med Cell Longev ID 6190609:10p.RatLiver
Kidney
Fibroblast
Holzem 2016 FASEB J2016Holzem KM, Vinnakota KC, Ravikumar VK, Madden EJ, Ewald GA, Dikranian K, Beard DA, Efimov IR (2016) Mitochondrial structure and function are not different between nonfailing donor and end-stage failing human hearts. FASEB J 30:2698-707.HumanHeart
Johnson 2016 Stem Cells Dev2016Johnson J, Lee W, Frazier AE, Vaghjiani V, Laskowski A, Rodriguez AL, Cagnone GL, McKenzie M, White SJ, Nisbet DR, Thorburn DR, St John JC (2016) Deletion of the complex I subunit NDUFS4 adversely modulates cellular differentiation. Stem Cells Dev 25:239-50.MouseStem cells
Rackham 2016 Cell Rep2016Rackham O, Busch JD, Matic S, Siira SJ, Kuznetsova I, Atanassov I, Ermer JA, Shearwood AM, Richman TR, Stewart JB, Mourier A, Milenkovic D, Larsson NG, Filipovska A (2016) Hierarchical RNA processing is required for mitochondrial ribosome assembly. Cell Rep 16:1874-90.MouseHeart
Lores-Arnaiz 2016 Neurochem Res2016Lores-Arnaiz S, Lombardi P, Karadayian AG, Orgambide F, Cicerchia D, Bustamante J (2016) Brain cortex mitochondrial bioenergetics in synaptosomes and non-synaptic mitochondria during aging. Neurochem Res 41:353-63.MouseNervous system
Chennamsetty 2016 Cell Rep2016Chennamsetty I, Coronado M, Contrepois K, Keller MP, Carcamo-Orive I, Sandin J, Fajardo G, Whittle AJ, Fathzadeh M, Snyder M, Reaven G, Attie AD, Bernstein D, Quertermous T, Knowles JW (2016) Nat1 deficiency is associated with mitochondrial dysfunction and exercise intolerance in mice. Cell Rep 17:527-40.MouseHeart
Fat
Schiffer 2016 Am J Physiol Cell Physiol2016Schiffer TA, Peleli M, Sundqvist ML, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2016) Control of human energy expenditure by cytochrome c oxidase subunit IV-2. Am J Physiol Cell Physiol 311:C452-61.HumanHEK
Skeletal muscle
Klepinin 2016 J Bioenerg Biomembr2016Klepinin A, Ounpuu L, Guzun R, Chekulayev V, Timohhina N, Tepp K, Shevchuk I, Schlattner U, Kaambre T (2016) Simple oxygraphic analysis for the presence of adenylate kinase 1 and 2 in normal and tumor cells. J Bioenerg Biomembr 48:531-48.Human
Rat
Mouse
Heart
Nervous system
Endothelial;epithelial;mesothelial cell
Genital
Hagl 2016 Nutr Neurosci2016Hagl S, Berressem D, Grewal R, Grebenstein N, Frank J, Eckert GP (2016) Rice bran extract improves mitochondrial dysfunction in brains of aged NMRI mice. Nutr Neurosci 19:1-10.MouseNervous system
Seiferling 2016 EMBO Rep2016Seiferling D, Szczepanowska K, Becker C, Senft K, Hermans S, Maiti P, König T, Kukat A, Trifunovic A (2016) Loss of CLPP alleviates mitochondrial cardiomyopathy without affecting the mammalian UPRmt. EMBO Rep 17:953-64.MouseHeart
Hagl 2016 Neuromolecular Med2016Hagl S, Asseburg H, Heinrich M, Sus N, Blumrich EM, Dringen R, Frank J, Eckert GP (2016) Effects of long-term rice bran extract supplementation on survival, cognition and brain mitochondrial function in aged NMRI mice. Neuromolecular Med 18:347-63.MouseNervous system
Jardim-Messeder 2016 Anticancer Res2016Jardim-Messeder D, Moreira-Pacheco F (2016) 3-Bromopyruvic acid inhibits Tricarboxylic acid cycle and glutaminolysis in HepG2 cells. Anticancer Res 36:2233-41.MouseKidney
Liver
Khattar 2016 J Neurosci Methods2016Khattar NK, Yablonska S, Baranov SV, Baranova OV, Kretz ES, Larkin TM, Carlisle DL, Richardson RM, Friedlander RM (2016) Isolation of functionally active and highly purified neuronal mitochondria from human cortex. J Neurosci Methods 263:1-6.Human
Mouse
Nervous system
Liepinsh 2016 Biochem J2016Liepinsh E, Makrecka-Kuka M, Volska K, Kuka J, Makarova E, Antone U, Sevostjanovs E, Vilskersts R, Strods A, Tars K, Dambrova M (2016) Long-chain acylcarnitines determine ischaemia/reperfusion-induced damage in heart mitochondria. Biochem J 473:1191-202.RatHeart
Piwonska 2016 Acta Neurobiol Exp (Wars)2016Piwońska M, Szewczyk A, Schröder UH, Reymann KG, Bednarczyk P (2016) Effectors of large-conductance calcium-activated potassium channel modulate glutamate excitotoxicity in organotypic hippocampal slice cultures. Acta Neurobiol Exp (Wars) 76:20-31.RatNervous system
Van Hoose 2016 J Nutr Biochem2016Van Hoose PM, Kelm NQ, Piell KM, Cole MP (2016) Conjugated linoleic acid and nitrite attenuate mitochondrial dysfunction during myocardial ischemia. J Nutr Biochem 34:8-16.MouseHeart
Pesta 2016 FASEB J2016Pesta DH, Tsirigotis DN, Befroy DE, Caballero D, Jurczak MJ, Rahimi Y, Cline GW, Dufour S, Birkenfeld AL, Rothman DL, Carpenter TO, Insogna K, Petersen KF, Bergwitz C, Shulman GI (2016) Hypophosphatemia promotes lower rates of muscle ATP synthesis. FASEB J 30:3378-87.MouseSkeletal muscle
Wolter 2016 J Thromb Haemost2016Wolter J, Schild L, Bock F, Hellwig A, Gadi I, Al-Dabet MM, Ranjan S, Rönicke R, Nawroth PP, Petersen KU, Mawrin C, Shahzad K, Isermann B (2016) Thrombomodulin-dependent protein C activation is required for mitochondrial function and myelination in the central nervous system. J Thromb Haemost 14:2212-26.MouseNervous system
Du 2016 J Exp Biol2016Du SN, Mahalingam S, Borowiec BG, Scott GR (2016) Mitochondrial physiology and reactive oxygen species production are altered by hypoxia acclimation in killifish (Fundulus heteroclitus). J Exp Biol 219:1130-8.FishesLiver
Ivarsson 2016 Physiol Behav2016Ivarsson N, Schiffer TA, Hernández A, Lanner JT, Weitzberg E, Lundberg JO, Westerblad H (2016) Dietary nitrate markedly improves voluntary running in mice. Physiol Behav 168:55-61.MouseSkeletal muscle
Chang 2016 Transl Res2016Chang JC, Wu SL, Liu KH, Chen YH, Chuang CS, Cheng FC, Su HL, Wei YH, Kuo SJ, Liu CS (2016) Allogeneic/xenogeneic transplantation of peptide-labeled mitochondria in Parkinson's disease: restoration of mitochondria functions and attenuation of 6-hydroxydopamine-induced neurotoxicity. Transl Res 170:40-56.RatNervous system
Other cell lines
Nemeth 2016 FASEB J2016Németh B, Doczi J, Csete D, Kacso G, Ravasz D, Adams D, Kiss G, Nagy AM, Horvath G, Tretter L, Mócsai A, Csépányi-Kömi R, Iordanov I, Adam-Vizi V, Chinopoulos C (2016) Abolition of mitochondrial substrate-level phosphorylation by itaconic acid produced by LPS-induced Irg1 expression in cells of murine macrophage lineage. FASEB J 30:286-300.MouseLiver
Milerova 2016 Mol Cell Biochem2016Milerová M, Drahota Z, Chytilová A, Tauchmannová K, Houštěk J, Ošťádal B (2016) Sex difference in the sensitivity of cardiac mitochondrial permeability transition pore to calcium load. Mol Cell Biochem 412:147-54.RatHeart
Van Zutphen 2016 J Hepatol2016van Zutphen T, Ciapaite J, Bloks VW, Ackereley C, Gerding A, Jurdzinski A, Allgayer de Moraes R, Zhang L, Wolters JC, Bischoff R, Wanders RJ, Houten SM, Bronte-Tinkew D, Shatseva T, Lewis GF, Groen AK, Reijngoud DJ, Bakker BM, Jonker JW, Kim PK, Bandsma RH (2016) Malnutrition-associated liver steatosis and ATP depletion is caused by peroxisomal and mitochondrial dysfunction. J Hepatol 65:1198-1208.RatLiver
McFarlane 2016 Thesis2016McFarlane SV (2016) Temperature-dependent alterations of brown adipose tissue metabolism during hibernation in the thirteen-lined ground squirrel, Ictidomys tridecemlineatus. Dissertation p74.Other mammalsFat
Williams 2016 Diabetes2016Williams AS, Trefts E, Lantier L, Grueter C, Bracy DP, James FD, Pozzi A, Zent R, Wasserman DH (2016) Integrin-linked kinase is necessary for the development of diet-induced hepatic insulin resistance. Diabetes 66:325-34.MouseLiver
Takahashi 2016 Exp Gerontol2016Takahashi K, Ohsawa I, Shirasawa T, Takahashi M (2016) Early-onset motor impairment and increased accumulation of phosphorylated α-synuclein in the motor cortex of normal aging mice are ameliorated by coenzyme Q. Exp Gerontol 81:65-75.MouseNervous system
Lashbrook 2016 Thesis2016Lashbrook M (2016) Functional responses of cardiac and skeletal muscle mitochondria to short-term obesity: are all obesities the same? Master's Thesis 63pp.Mouse
Other mammals
Heart
Skeletal muscle
Singh 2016 Mol Neurobiol2016Singh N, Hroudová J, Fišar Z (2016) In vitro effects of cognitives and nootropics on mitochondrial respiration and monoamine oxidase activity. Mol Neurobiol 54:5894-904.PigNervous system
Viola 2016 JACC: Basic to Translational Science2016Viola HM, Johnstone VPA, Szappanos HC, Richman TR, Tsoutsman T, Filipovska A, Semsarian C, Seidman JG, Seidman CE, Hool LC (2016) The role of the L-type Ca2+ channel in altered metabolic activity in a murine model of hypertrophic cardiomyopathy. JACC: Basic to Translational Science 1: 61–72.MouseHeart
Mezera 2016 Oxid Med Cell Longev2016Mezera V, Endlicher R, Kucera O, Sobotka O, Drahota Z, Cervinkova Z (2016) Effects of epigallocatechin gallate on tert-butyl hydroperoxide-induced mitochondrial dysfunction in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 7573131:8pp.RatLiver
Schoenfeld 2016 J Cereb Blood Flow Metab2016Schönfeld P, Reiser G (2016) Inhibition of b-oxidation is not a valid therapeutic tool for reducing oxidative stress in conditions of neurodegeneration. J Cereb Blood Flow Metab 37:848-54.RatNervous system
Amigo 2016 Aging Cell2016Amigo I, Menezes-Filho SL, Luévano-Martínez LA, Chausse B, Kowaltowski AJ (2016) Caloric restriction increases brain mitochondrial calcium retention capacity and protects against excitotoxicity. Aging Cell 16:73-81.MouseNervous system
Hamilton 2016 Am J Physiol Heart Circ Physiol2016Hamilton DJ, Zhang A, Li S, Cao TN, Smith JA, Vedula I, Cordero-Reyes AM, Youker KA, Torre-Amione G, Gupte AA (2016) Combination of angiotensin II and l-NG-nitroarginine methyl ester exacerbates mitochondrial dysfunction and oxidative stress to cause heart failure. Am J Physiol Heart Circ Physiol 310:H667-80.MouseHeart
Mourier 2015 J Cell Biol2015Mourier A, Motori E, Brandt T, Lagouge M, Atanassov I, Galinier A, Rappl G, Brodesser S, Hultenby K, Dieterich C, Larsson NG (2015) Mitofusin 2 is required to maintain mitochondrial coenzyme Q levels. J Cell Biol 208:429-42.MouseHeart
Fibroblast
Wessels 2015 Am J Physiol2015Wessels B, van den Broek NM, Ciapaite J, Houten SM, Wanders RJ, Nicolay K, Prompers JJ (2015) Carnitine supplementation in high-fat diet-fed rats does not ameliorate lipid-induced skeletal muscle mitochondrial dysfunction in vivo. Am J Physiol 309(7):E670-8.RatSkeletal muscle
Du 2015 J Biol Chem2015Du J, Rountree A, Cleghorn WM, Contreras L, Lindsay KJ, Sadilek M, Gu H, Djukovic D, Raftery D, Satrustegui J, Kanow M, Chan L, Tsang SH, Sweet IR, Hurley JB (2015) Phototransduction influences metabolic flux and nucleotide metabolism in mouse retina. J Biol Chem 291:4698-710.MouseNervous system
Islet cell;pancreas;thymus
Schwarzkopf 2015 Neuroscience2015Schwarzkopf TM, Koch K, Klein J (2015) Reduced severity of ischemic stroke and improvement of mitochondrial function after dietary treatment with the anaplerotic substance triheptanoin. Neuroscience 300:201-9.MouseNervous system
Ferrera 2015 J Thorac Cardiovasc Surg2015Ferrera R, Benhabbouche S, Da Silva CC, Alam MR, Ovize M (2015) Delayed low pressure at reperfusion: A new approach for cardioprotection. J Thorac Cardiovasc Surg 150:1641-8.RatHeart
Grimm 2015 Exp Gerontol2015Grimm C, Osiewacz HD (2015) Manganese rescues adverse effects on lifespan and development in Podospora anserina challenged by excess hydrogen peroxide. Exp Gerontol 63:8-17.Fungi
Chweih 2015 Exp Physiol2015Chweih H, Castilho RF, Figueira TR (2015) Tissue and sex specificities in Ca(2+) handling by isolated mitochondria in conditions avoiding the permeability transition. Exp Physiol 100(9):1073-92.RatHeart
Skeletal muscle
Nervous system
Liver
Den Besten 2015 Diabetes2015den Besten G, Bleeker A, Gerding A, van Eunen K, Havinga R, van Dijk TH, Oosterveer MH, Jonker JW, Groen AK, Reijngoud DJ, Bakker BM (2015) Short-chain fatty acids protect against high-fat diet-induced obesity via a PPARγ-dependent switch from lipogenesis to fat oxidation. Diabetes 64:2398-408.MouseLiver
Flatters 2015 Prog Mol Biol Transl Sci2015Flatters SJ (2015) The contribution of mitochondria to sensory processing and pain. Prog Mol Biol Transl Sci 131:119-46.RatNervous system
Czerniczyniec 2015 J Bioenerg Biomembr2015Czerniczyniec A, Lanza EM, Karadayian AG, Bustamante J, Lores-Arnaiz S (2015) Impairment of striatal mitochondrial function by acute paraquat poisoning. J Bioenerg Biomembr 47:395-408.RatNervous system
Jezek 2015 Antioxid Redox Signal2015Ježek J, Dlasková A, Zelenka J, Jabůrek M, Ježek P (2015) H2O2-activated mitochondrial phospholipase iPLA2γ prevents lipotoxic oxidative stress in synergy with UCP2, amplifies signaling via G-protein-coupled receptor GPR40, and regulates insulin secretion in pancreatic β-cells. Antioxid Redox Signal 23:958-72.Islet cell;pancreas;thymus
Doerrier 2015 Thesis2015Doerrier C (2015) Estudio bioenergetica mitochondrial en la sepsis experimental y efecto protector de la Melatonina. Doctoral Thesis p154.MouseHeart
Liver
Guzun 2015 Acta Physiol (Oxf)2015Guzun R, Kaambre T, Bagur R, Grichine A, Usson Y, Varikmaa M, Anmann T, Tepp K, Timohhina N, Shevchuk I, Chekulayev V, Boucher F, Dos Santos P, Schlattner U, Wallimann T, Kuznetsov AV, Dzeja P, Aliev M, Saks V (2015) Modular organization of cardiac energy metabolism:energy conversion, transfer and feedback regulation. Acta Physiol (Oxf) 213:84-106.RatHeart
Schoettl 2015 Mol Metab2015Schöttl T, Kappler L, Fromme T, Klingenspor M (2015) Limited OXPHOS capacity in white adipocytes is a hallmark of obesity in laboratory mice irrespective of the glucose tolerance status. Mol Metab 4:631-42.MouseFat
Other cell lines
Krumschnabel 2015 Methods Mol Biol2015
O2k-Protocols contents
Krumschnabel G, Fontana-Ayoub M, Sumbalova Z, Heidler J, Gauper K, Fasching M, Gnaiger E (2015) Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production. Methods Mol Biol 1264:245-61.
MouseNervous system
Zelenka 2015 Oxid Med Cell Longev2015Zelenka J, Dvořák A, Alán L (2015) L-lactate protects skin fibroblasts against aging-associated mitochondrial dysfunction via mitohormesis. Oxid Med Cell Longev 2015:351698.RatLiver
Endothelial;epithelial;mesothelial cell
Fibroblast
Schoettl 2015 Endocrinology2015Schöttl T, Kappler L, Braun K, Fromme T, Klingenspor M (2015) Limited mitochondrial capacity of visceral versus subcutaneous white adipocytes in male C57BL/6N mice. Endocrinology 156:923-33.MouseFat
Correa 2015 Critical Care Horizon2015Corrêa TD, Jakob SM, Takala J (2015) Mitochondrial function in sepsis. Critical Care Horizon 1:31-41 .PigLiver
Moore 2015 PhD Thesis2015Moore D (2015) Biostabilization of lipid bilayers: dealing with water stress in embryos of Artemia franciscana. PhD Thesis 1-111.RatLiver
Warne 2015 J Biol Chem2015Warne J, Pryce G, Hill J, Shi X, Lennerås F, Puentes F, Kip M, Hilditch L, Walker P, Simone MI, Chan AW, Towers GJ, Coker A, Duchen MR, Szabadkai G, Baker D, Selwood D (2015) Selective inhibition of the mitochondrial permeability transition pore protects against neuro-degeneration in experimental multiple sclerosis. J Biol Chem 291:4356-73.MouseLiver
Acosta 2015 Obesity (Silver Spring)2015Acosta A, Camilleri M, Shin A, Vazquez-Roque MI, Iturrino J, Lanza IR, Nair KS, Burton D, O'Neill J, Eckert D, Carlson P, Vella A, Zinsmeister AR (2015) Association of UCP-3 rs1626521 with obesity and stomach functions in humans. Obesity (Silver Spring) 23:898-906.HumanSkeletal muscle
Van Hoose 2015 Thesis2015Van Hoose P (2015) Co-treatment with conjugated linoleic acid and nitrite modulates mitochondrial respiration and electron transport chain activity in vivo and attenuates mitochondrial dysfunction during cardiac injury. Dissertations p128.MouseHeart
Laursen 2015 Proc Natl Acad Sci USA2015Laursen WJ, Mastrotto M, Pesta D, Funk OH, Goodman JB, Merriman DK, Ingolia N, Shulman GI, Bagriantsev SN, Gracheva EO (2015) Neuronal UCP1 expression suggests a mechanism for local thermogenesis during hibernation. Proc Natl Acad Sci USA 112:1607-12.Other mammalsNervous system
HEK
Hagl 2015 Neurochem Int2015Hagl S, Kocher A, Schiborr C, Kolesova N, Frank J, Eckert GP (2015) Curcumin micelles improve mitochondrial function in neuronal PC12 cells and brains of NMRI mice - Impact on bioavailability. Neurochem Int 89:234-42.MouseNervous system
Hejzlarova 2015 Biochem J2015Hejzlarová K, Kaplanová V, Nůsková H, Kovářová N, Ješina P, Drahota Z, Mráček T, Seneca S, Houštěk J (2015) Alteration of structure and function of ATP synthase and cytochrome c oxidase by lack of Fo-a and Cox3 subunits caused by mitochondrial DNA 9205delTA mutation. Biochem J 466:601-11.HumanOther cell lines
Christiansen 2015 Am J Physiol Heart Circ Physiol2015Christiansen LB, Dela F, Koch J, Hansen CN, Leifsson PS, Yokota T (2015) Impaired cardiac mitochondrial oxidative phosphorylation and enhanced mitochondrial oxidative stress in feline hypertrophic cardiomyopathy. Am J Physiol Heart Circ Physiol 308:H1237-47.CatHeart
Skeletal muscle
Maiti 2015 PhD Thesis2015Maiti P (2015) The role of caseinolytic mitochondrial matrix peptidase proteolytic subunit (CLPP) in regulation of mitochondrial ribosome biogenesis in mammals. PhD Thesis 1-120.MouseHeart
Clemens 2015 Brain2015Clemens LE, Weber JJ, Wlodkowski TT, Yu-Taeger L, Michaud M, Calaminus C, Eckert SH, Gaca J, Weiss A, Magg JC, Jansson EK, Eckert GP, Pichler BJ, Bordet T, Pruss RM, Riess O, Nguyen HP (2015) Olesoxime suppresses calpain activation and mutant huntingtin fragmentation in the BACHD rat. Brain 138:3632-53.RatNervous system
Koliaki 2015 Cell Metab2015Koliaki C, Szendroedi J, Kaul K, Jelenik T, Nowotny P, Jankowiak F, Herder C, Carstensen M, Krausch M, Knoefel WT, Schlensak M, Roden M (2015) Adaptation of hepatic mitochondrial function in humans with non-alcoholic fatty liver is lost in steatohepatitis. Cell Metab 21:739-46.HumanLiver
Dungel 2015 Free Radic Biol Med2015Dungel P, Perlinger M, Weidinger A, Redl H, Kozlov AV (2015) The cytoprotective effect of nitrite is based on the formation of dinitrosyl iron complexes. Free Radic Biol Med 89:300-10.RatLiver
Gainutdinov 2015 Arch Biochem Biophys2015Gainutdinov T, Molkentin JD, Siemen D, Ziemer M, Debska-Vielhaber G, Vielhaber S, Gizatullina Z, Orynbayeva Z, Gellerich FN (2015) Knockout of cyclophilin D in Ppif(-/-) mice increases stability of brain mitochondria against Ca(2+) stress. Arch Biochem Biophys 579:40-6.MouseNervous system
Karadayian 2015 Neuroscience2015Karadayian AG, Bustamante J, Czerniczyniec A, Lombardi P, Cutrera RA, Lores-Arnaiz S (2015) Alcohol hangover induces mitochondrial dysfunction and free radical production in mouse cerebellum. Neuroscience 304:47-59.MouseNervous system
Suarez 2015 PhD Thesis2015Suárez Cunza S (2015) Actividad captadora de Radicales libres y Effecto antioxidante de Metabolitos secundarios del extracto acuoso des "Allium sativum" var. Huaralino (Ajo) en Modelos in vitro. PhD Thesis 1-39.RatLiver
Wessels 2015 Diabetes Obes Metab2015Wessels B, Ciapaite J, van den Broek NM, Houten SM, Nicolay K, Prompers JJ (2015) Pioglitazone treatment restores in vivo muscle oxidative capacity in a rat model of diabetes. Diabetes Obes Metab 17:52-60.RatSkeletal muscle
Tapia 2015 Crit Care2015Tapia P, Soto D, Bruhn A, Alegría L, Jarufe N, Luengo C, Kattan E, Regueira T, Meissner A, Menchaca R, Vives MI, Echeverría N, Ospina-Tascón G, Bakker J, Hernández G (2015) Impairment of exogenous lactate clearance in experimental hyperdynamic septic shock is not related to total liver hypoperfusion. Crit Care 19:188.Other mammalsLiver
Fouret 2015 Biochim Biophys Acta2015Fouret G, Tolika E, Lecomte J, Bonafos B, Aoun M, Murphy MP, Ferreri C, Chatgilialoglu C, Dubreucq E, Coudray C, Feillet-Coudray C (2015) The mitochondrial-targeted antioxidant, MitoQ, increases liver mitochondrial cardiolipin content in obesogenic diet-fed rats. Biochim Biophys Acta 1847:1025-35.RatLiver
Torelli 2015 Free Radic Biol Med2015Torelli NQ, Ferreira-Júnior JR, Kowaltowski AJ, da Cunha FM (2015) RTG1- and RTG2-dependent retrograde signaling controls mitochondrial activity and stress resistance in Saccharomyces cerevisiae. Free Radic Biol Med 81C:30-7.Saccharomyces cerevisiae
Ziemer 2015 Dissertation2015Ziemer M (2015) Untersuchungen zur Aktivität der mitochondrialen Permeabilitätstransitionspore in der Cyclophilin-D-Knock-out-Maus (Ppif-/-). Dissertation 1-72.MouseLiver
Lemoine 2015 Transplantation2015Lemoine S, Pillot B, Rognant N, Augeul L, Rayberin M, Varennes A, Laville M, Ovize M, Juillard L (2015) Postconditioning with cyclosporine a reduces early renal dysfunction by inhibiting mitochondrial permeability transition. Transplantation. 99:717-23MouseKidney
Youcef 2015 Biochem Pharmacol2015Youcef G, Belaidi E, Waeckel L, Fazal L, Clemessy M, Vincent MP, Zadigue G, Richer C, Alhenc-Gelas F, Ovize M, Pizard A (2015) Tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse. Biochem Pharmacol 94:22-9.MouseHeart
Hanssen 2015 Diabetologia2015Hanssen MJ, Wierts R, Hoeks J, Gemmink A, Brans B, Mottaghy FM, Schrauwen P, van Marken Lichtenbelt WD (2015) Glucose uptake in human brown adipose tissue is impaired upon fasting-induced insulin resistance. Diabetologia 58:586-95.HumanSkeletal muscle
Aroor 2015 Diabetes2015Aroor AR, Habibi J, Ford DA, Nistala R, Lastra G, Manrique C, Dunham MM, Ford KD, Thyfault JP, Parks EJ, Sowers JR, Rector RS (2015) Dipeptidyl peptidase-4 inhibition ameliorates western diet-induced hepatic steatosis and insulin resistance through hepatic lipid remodeling and modulation of hepatic mitochondrial function. Diabetes 64:1988-2001.MouseLiver
Li 2015 Oxid Med Cell Longev2015Li H, Miao W, Ma J, Xv Z, Bo H, Li J, Zhang Y and Ji LL (2015) Acute Exercise-Induced Mitochondrial Stress Triggers an Inflammatory Response in the Myocardium via NLRP3 Inflammasome Activation with Mitophagy. Oxid Med Cell Longev: 357150.RatHeart
Chausse 2015 PLoS One2015Chausse B, Vieira-Lara MA, Sanchez AB, Medeiros MH, Kowaltowski AJ (2015) Intermittent fasting results in tissue-specific changes in bioenergetics and redox state. PLoS One 10:e0120413.RatHeart
Skeletal muscle
Nervous system
Liver
Lim 2015 Am J Cancer Res2015Lim SC, Carey KT, McKenzie M (2015) Anti-cancer analogues ME-143 and ME-344 exert toxicity by directly inhibiting mitochondrial NADH: ubiquinone oxidoreductase (Complex I). Am J Cancer Res 5:689-701.HumanKidney
Other cell lines
HEK
HeLa
Fibroblast
Muellebner 2015 Biomolecules2015Müllebner A, Moldzio R, Redl H, Kozlov AV, Duvigneau JC (2015) Heme degradation by heme oxygenase protects mitochondria but induces ER stress via formed bilirubin. Biomolecules 5:679-701.RatLiver
Herbst 2015 J Physiol2015Herbst EA, Holloway GP (2015) Permeabilization of brain tissue in situ enables multi-region analysis of mitochondrial function in a single mouse brain. J Physiol 593:787-801.MouseNervous system
Silachev 2015 Chem Biol Interact2015Silachev DN, Gulyaev MV, Zorova LD, Khailova LS, Gubsky LV, Pirogov YA, Plotnikov EY, Sukhikh GT, Zorov DB (2015) Magnetic resonance spectroscopy of the ischemic brain under lithium treatment. Link to mitochondrial disorders under stroke. Chem Biol Interact 237:175-82.RatNervous system
Kruska 2015 Biochim Biophys Acta2015Kruska N, Schönfeld P, Pujol A, Reiser G (2015) Astrocytes and mitochondria from adrenoleukodystrophy protein (ABCD1)-deficient mice reveal that the adrenoleukodystrophy-associated very long-chain fatty acids target several cellular energy-dependent functions. Biochim Biophys Acta 1852:925-36.MouseNervous system
Gram 2015 J Physiol2015Gram M, Vigelsø A, Yokota T, Helge JW, Dela F, Hey-Mogensen M (2015) Skeletal muscle mitochondrial H2O2 emission increases with immobilization and decreases after aerobic training in young and older men. J Physiol 593:4011-27.HumanSkeletal muscle
Agil 2015 J Pineal Res2015Agil A, El-Hammadi M, Jiménez-Aranda A, Tassi M, Abdo W, Fernández-Vázquez G, Reiter RJ (2015) Melatonin reduces hepatic mitochondrial dysfunction in diabetic obese rats. J Pineal Res 59:70-9.RatLiver
Skemiene 2015 FEBS J2015Skemiene K, Liobikas J, Borutaite V (2015) Anthocyanins as substrates for mitochondrial complex I - protective effect against heart ischemic injury. FEBS J 282:963-71.RatHeart
Sheldon 2015 Am J Physiol Gastrointest Liver Physiol2015Sheldon RD, Padilla J, Jenkins NT, Laughlin MH, Rector RS (2015) Chronic NOS inhibition accelerates NAFLD progression in an obese rat model. Am J Physiol Gastrointest Liver Physiol 308:G540-9.RatLiver
Whitfield 2015 J Physiol2015Whitfield J, Ludzki A, Heigenhauser GJ, Senden JM, Verdijk LB, van Loon LJ, Spriet LL, Holloway GP (2015) Beetroot juice supplementation reduces whole body oxygen consumption but does not improve indices of mitochondrial efficiency in human skeletal muscle. J Physiol 594:421-35.HumanSkeletal muscle
Richman 2015 PLoS Genet2015Richman TR, Ermer JA, Davies SM, Perks KL, Viola HM, Shearwood AM, Hool LC, Rackham O, Filipovska A (2015) Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction. PLoS Genet 11:e1005089.MouseHeart
Liver
Johnson 2015 Aging Cell2015Johnson ML, Lalia AZ, Dasari S, Pallauf M, Fitch M, Hellerstein MK, Lanza IR (2015) Eicosapentaenoic acid but not docosahexaenoic acid restores skeletal muscle mitochondrial oxidative capacity in old mice. Aging Cell 14:734-43.MouseSkeletal muscle
Tan 2015 Cell Metab2015Tan AS, Baty JW, Dong L, Bezawork-Geleta A, Endaya B, Goodwin J, Bajzikova M, Kovarova J, Peterka M, Yan B, Pesdar EA, Sobol M, Filimonenko A, Stuart S, Vondrusova M, Kluckova K, Sachaphibulkij K, Rohlena J, Hozak P, Truksa J, Eccles D, Haupt LM, Griffiths LR, Neuzil J, Berridge MV (2015) Mitochondrial genome acquisition restores respiratory function and tumorigenic potential of cancer cells without mitochondrial DNA. Cell Metab 21:81-94.Human
Mouse
Endothelial;epithelial;mesothelial cell
Genital
Other cell lines
Abou-Hamdan 2015 Methods Enzymol2015Abou-Hamdan A, Guedouari-Bounihi H, Lenoir V, Andriamihaja M, Blachier F, Bouillaud F (2015) Oxidation of H2S in mammalian cells and mitochondria. Methods Enzymol 554:201-28.Human
Pig
Mouse
Rat
Heart
Nervous system
Liver
Kidney
Genital
CHO
Neuroblastoma
Fibroblast
Wang 2015 Nat Commun2015Wang Y, Oxer D, Hekimi S (2015) Mitochondrial function and lifespan of mice with controlled ubiquinone biosynthesis. Nat Commun 6:6393.MouseHeart
Kidney
Skeletal muscle
Soares 2015 PLoS One2015Soares JB, Gaviraghi A, Oliveira MF (2015) Mitochondrial physiology in the major arbovirus vector Aedes aegypti: substrate preferences and sexual differences define respiratory capacity and superoxide production. PLoS One 10:e0120600.HexapodsSkeletal muscle
Kluckova 2015 Cell Death Dis2015Kluckova K, Sticha M, Cerny J, Mracek T, Dong L, Drahota Z, Gottlieb E, Neuzil J, Rohlena J (2015) Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation. Cell Death Dis 6:e1749.Other mammalsLung;gill
Other cell lines
Fibroblast
Jardim-Messeder 2015 New Phytol2015Jardim-Messeder D, Caverzan A, Rauber R, de Souza Ferreira E, Margis-Pinheiro M, Galina A (2015) Succinate dehydrogenase (mitochondrial complex II) is a source of reactive oxygen species in plants and regulates development and stress responses. New Phytol 208:776-89.Plants
Hey-Mogensen 2015 J Physiol2015Hey-Mogensen M, Gram M, Jensen MB, Lund MT, Hansen CN, Scheibye-Knudsen M, Bohr VA, Dela F (2015) A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function. J Physiol 593:3991-4010.HumanSkeletal muscle
Margulies 2015 Brain Pathol2015Margulies SS, Kilbaugh T, Sullivan S, Smith C, Propert K, Byro M, Saliga K, Costine BA, Duhaime AC (2015) Establishing a clinically relevant large animal model platform for TBI therapy development: using Cyclosporin A as a case study. Brain Pathol 25:289-303.PigNervous system
Kang 2015 Int J Clin Exp Med2015Kang M, Zhao L, Ren M, Deng M, Li C (2015) Reduced metallothionein expression induced by Zinc deficiency results in apoptosis in hepatic stellate cell line LX-2. Int J Clin Exp Med 8:20603-9.HumanLiver
Other cell lines
Hezel 2015 Redox Biol2015Hezel MP, Liu M, Schiffer TA, Larsen FJ, Checa A, Wheelock CE, Carlström M, Lundberg JO, Weitzberg E (2015) Effects of long-term dietary nitrate supplementation in mice. Redox Biol 5:234-42.MouseSkeletal muscle
Papazova 2015 Am J Physiol Renal Physiol2015Papazova DA, Friederich-Persson M, Joles JA, Verhaar MC (2015) Renal transplantation induces mitochondrial uncoupling, increased kidney oxygen consumption, and decreased kidney oxygen tension. Am J Physiol Renal Physiol 308:F22-8.RatKidney
Miwa 2015 Free Radic Biol Med2015Miwa S, Treumann A, Bell A, Vistoli G, Nelson G, Hay S, von Zglinicki T (2015) Carboxylesterase converts Amplex red to resorufin: Implications for mitochondrial H2O2 release assays.. Free Radic Biol Med 90:173-83.MouseLiver
Makrecka-Kuka 2015 Biomolecules2015
O2k-Protocols contents
Makrecka-Kuka M, Krumschnabel G, Gnaiger E (2015) High-resolution respirometry for simultaneous measurement of oxygen and hydrogen peroxide fluxes in permeabilized cells, tissue homogenate and isolated mitochondria. Biomolecules 5:1319-38.
Human
Mouse
Heart
Nervous system
HEK
Janssens 2015 Nutr Metab (Lond)2015Janssens S, Heemskerk MM, van den Berg SA, van Riel NA, Nicolay K, Willems van Dijk K, Prompers JJ (2015) Effects of low-stearate palm oil and high-stearate lard high-fat diets on rat liver lipid metabolism and glucose tolerance. Nutr Metab (Lond) 12:57.RatLiver
Jeger 2015 BioMed Res Internat2015Jeger V, Brandt S, Porta F, Jakob SM, Takala J, Djafarzadeh S (2015) Dose response of Endotoxin on hepatocyte and muscle mitochondrial respiration in vitro. BioMed Res Internat Article ID 353074:1-13.HumanSkeletal muscle
Liver
Other cell lines
Konopka 2015 Diabetes2015Konopka AR, Asante A, Lanza IR, Robinson MM, Johnson ML, Dalla Man C, Cobelli C, Amols MH, Irving BA, Nair KS (2015) Defects in mitochondrial efficiency and H2O2 emissions in obese women are restored to a lean phenotype with aerobic exercise training. Diabetes 64:2104-15.HumanSkeletal muscle
Hendricks 2015 Thesis2015Hendricks EW (2015) The impact of aging and estrogen therapy on synaptic mitochondrial bioenergetics in an Alzheimer's mouse model. Master Thesis 1-67.MouseNervous system
Schrauwen-Hinderling 2015 Antioxid Redox Signal2015Schrauwen-Hinderling VB, Kooi ME, Schrauwen P (2015) Mitochondrial function and diabetes; consequences for skeletal and cardiac muscle metabolism. Antioxid Redox Signal 24:39-51.HumanHeart
Skeletal muscle
Patil 2015 J Nutr Biochem2015Patil YN, Dille KN, Burk DH, Cortez CC, Gettys TW (2015) Cellular and molecular remodeling of inguinal adipose tissue mitochondria by dietary methionine restriction. J Nutr Biochem 26:1235-47.MouseSkeletal muscle
Liver
Fat
Labieniec-Watala 2015 Int J Pharm Sci Res2015Labieniec-Watala M, Przygodzki T, Siewiera K, Podsedek A, Watala C (2015) Facts and artifacts in the evaluation of the anti-diabetic activity of spent hop extract in rat hearts in the “experimental model of diabetes. Int J Pharm Sci Res 1:106.RatHeart
Plecita-Hlavata 2015 Am J Respir Cell Mol Biol2015Plecitá-Hlavatá L, Tauber J, Li M, Zhang H, Flockton AR, Pullamsetti SS, Chelladurai P, D'alessandro A, El Kasmi KC, Ježek P, Stenmark KR (2015) Constitutive reprogramming of fibroblast mitochondrial metabolism in pulmonary hypertension. Am J Respir Cell Mol Biol 55:47-57.Human
Bovines
Endothelial;epithelial;mesothelial cell
Fibroblast
Kucera 2015 Oxid Med Cell Longev2015Kucera O, Mezera V, Moravcova A, Endlicher R, Lotkova H, Drahota Z, Cervinkova Z (2015) In vitro toxicity of epigallocatechin gallate in rat liver mitochondria and hepatocytes. Oxid Med Cell Longev 2015:476180.RatLiver
Harrison 2015 J Appl Physiol2015Harrison DK, Fasching M, Fontana-Ayoub M, Gnaiger E (2015) Cytochrome redox states and respiratory control in mouse and beef heart mitochondria at steady-state levels of hypoxia. J Appl Physiol 119:1210-8.Mouse
Bovines
Heart
Irving 2015 J Clin Endocrinol Metab2015Irving BA, Lanza IR, Henderson GC, Rao RR, Spiegelman BM, Nair KS (2015) Combined training enhances skeletal muscle mitochondrial oxidative capacity independent of age. J Clin Endocrinol Metab 100:1654-63.HumanSkeletal muscle
Imran 2015 J Neurochem2015Imran I, Hillert MH, Klein J (2015) Early metabolic responses to lithium/pilocarpine-induced status epilepticus in rat brain. J Neurochem 135:1007-18.RatNervous system
Czerniczyniec 2015 Brain Res2015Czerniczyniec A, La Padula P, Bustamante J, Karadayian AG, Lores-Arnaiz S, Costa LE (2015) Mitochondrial function in rat cerebral cortex and hippocampus after short- and long-term hypobaric hypoxia. Brain Res 1598:66-75.RatNervous system
Joergensen 2015 J Cereb Blood Flow Metab2015Jørgensen T, Grunnet N, Quistorff B (2015) One-year high fat diet affects muscle-but not brain mitochondria. J Cereb Blood Flow Metab 35:943-50.RatSkeletal muscle
Nervous system
Petrus 2015 Can J Physiol Pharmacol2015Petruş A, Duicu OM, Sturza A, Noveanu L, Kiss L, Dănilă M, Baczkó I, Muntean DM, Jost N (2015) Modulation of mitochondrial respiratory function and ROS production by novel benzopyran analogues. Can J Physiol Pharmacol 93:811-8.RatHeart
Hagve 2015 Am J Physiol Endocrinol Metab2015Hagve M, Gjessing PF, Fuskevåg OM, Larsen TS, Irtun Ø (2015) Skeletal muscle mitochondria exhibit decreased pyruvate oxidation capacity and increased ROS emission during surgery-induced acute insulin resistance. Am J Physiol Endocrinol Metab 308:E613-20.PigSkeletal muscle
Liver
Sobotka 2015 Physiol Res2015Sobotka O, Drahota Z, Kučera O, Endlicher R, Rauchová H, Červinková Z (2015) The effect of α-tocopheryl succinate on succinate respiration in rat liver mitochondria. Physiol Res 64 Suppl 5:S609-15.RatLiver
Baraldi 2015 J Nutr Biochem2015Baraldi FG, Vicentini TM, Teodoro BG, Dalalio FM, Dechandt CR, Prado IM, Curti C, Cardoso FC, Uyemura SA, Alberici LC (2015) The combination of conjugated linoleic acid (CLA) and extra virgin olive oil increases mitochondrial and body metabolism and prevents CLA-associated insulin resistance and liver hypertrophy in C57Bl/6 mice. J Nutr Biochem 28:147-54.MouseLiver
Ortiz 2015 J Pineal Res2015Ortiz F, Acuña-Castroviejo D, Doerrier C, Dayoub JC, López LC, Venegas C, García JA, López A, Volt H, Luna-Sánchez M, Escames G (2015) Melatonin blunts the mitochondrial/NLRP3 connection and protects against radiation-induced oral mucositis. J Pineal Res 58:34-49.
Nordquist 2015 J Am Soc Nephrol2015Nordquist L, Friederich-Persson M, Fasching A, Liss P, Shoji K, Nangaku M, Hansell P, Palm F (2015) Activation of hypoxia-inducible factors prevents diabetic nephropathy. J Am Soc Nephrol 26:328-38.RatKidney
Van Ewijk 2015 Obesity (Silver Spring)2015van Ewijk PA, Paglialunga S, Kooi ME, Nunes PM, Gemmink A, Slenter J, Kornips E, Jörgensen JA, Hoeks J, Wildberger JE, Hesselink MK, Glatz JF, Heerschap A, Kersten S, Schrauwen P, Schrauwen-Hinderling VB (2015) Effects of high-fat feeding on ectopic fat storage and postprandial lipid metabolism in mouse offspring. Obesity (Silver Spring) 23:2242-50.MouseHeart
Liver
Bonsignore 2015 Mech Ageing Dev2015Bonsignore LA, Tooley JG, Van Hoose PM, Wang E, Cheng A, Cole MP, Schaner Tooley CE (2015) NRMT1 knockout mice exhibit phenotypes associated with impaired DNA repair and premature aging. Mech Ageing Dev 146-148:42-52.MouseLiver
Banh 2015 Comp Biochem Physiol B Biochem Mol Biol2015Banh S, Wiens L, Sotiri E, Treberg JR (2015) Mitochondrial reactive oxygen species production by fish muscle mitochondria: Potential role in acute heat-induced oxidative stress. Comp Biochem Physiol B Biochem Mol Biol 191:99-107.Rat
Fishes
Skeletal muscle
Ziak 2015 Mitochondrion2015Ziak J, Krajcova A, Jiroutkova K, Nemcova V, Dzupa V, Duska F (2015) Assessing the function of mitochondria in cytosolic context in human skeletal muscle: Adopting high-resolution respirometry to homogenate of needle biopsy tissue samples. Mitochondrion 21:106-12.HumanSkeletal muscle
MiPNet12.11 MitoRespiration2014-02-20
O2k-Protocols
Flux control ratios in isolated mitochondria. OXPHOS capacity and respiratory control.
Artemia
Crustaceans
Chausse 2014 Endocrinology2014Chausse B, Solon C, Caldeira da Silva CC, Masselli Dos Reis IG, Manchado-Gobatto FB, Gobatto CA, Velloso LA, Kowaltowski AJ (2014) Intermittent fasting induces hypothalamic modifications resulting in low feeding efficiency, low body mass and overeating. Endocrinology 9:e97673.RatSkeletal muscle
Littlejohns 2014 PLoS One2014Littlejohns B, Pasdois P, Duggan S, Bond AR, Heesom K, Jackson CL, Angelini GD, Halestrap AP, Suleiman MS (2014) Hearts from mice fed a non-obesogenic high-fat diet exhibit changes in their oxidative state, calcium and mitochondria in parallel with increased susceptibility to reperfusion injury. PLoS One 9:e100579.MouseHeart
Hagl 2014 J Alzheimers Dis b2014Hagl S, Heinrich M, Kocher A, Schiborr C, Frank J, Eckert GP (2014) Curcumin micelles improve mitochondrial function in a mouse model of Alzheimer’s disease. J Alzheimers Dis 1:80-3.MouseNervous system
De Palma 2014 Skelet Muscle2014De Palma C, Morisi F, Pambianco S, Assi E, Touvier T, Russo S, Perrotta C, Romanello V, Carnio S, Cappello V, Pellegrino P, Moscheni C, Bassi MT, Sandri M, Cervia D, Clementi E (2014) Deficient nitric oxide signalling impairs skeletal muscle growth and performance: involvement of mitochondrial dysregulation. Skelet Muscle 4:22.MouseSkeletal muscle
Garnol 2014 Physiol Res2014Garnol T, Endlicher R, Kučera O, Drahota Z, Cervinková Z (2014) Impairment of mitochondrial function of rat hepatocytes by high fat diet and oxidative stress. Physiol Res 63:271-4.RatLiver
Varikmaa 2014 Biochim Biophys Acta2014Varikmaa M, Bagur R, Kaambre T, Grichine A, Timohhina N, Tepp K, Shevchuk I, Chekulayev V, Metsis M, Boucher F, Saks V, Kuznetsov AV, Guzun R (2014) Role of mitochondria-cytoskeleton interactions in respiration regulation and mitochondrial organization in striated muscles. Biochim Biophys Acta 1837:232-45.RatHeart
Skeletal muscle
Fisar 2014 Toxicol Lett2014Fišar Z, Singh N, Hroudová J (2014) Cannabinoid-induced changes in respiration of brain mitochondria. Toxicol Lett 231:62-71.PigNervous system
Beiral 2014 Cell Transplant2014Beiral HJ, Rodrigues-Ferreira C, Fernandes AM, Gonsalez SR, Mortari NC, Takiya CM, Sorenson MM, Figueiredo-Freitas C, Galina A, Vieyra A (2014) The impact of stem cells on electron fluxes, proton translocation and ATP synthesis in kidney mitochondria after ischemia/reperfusion. Cell Transplant 23:207-20.RatKidney
Stem cells
Rauchova 2014 Int J Biochem Cell Biol2014Rauchová H, Vokurková M, Drahota Z (2014) Inhibition of mitochondrial glycerol-3-phosphate dehydrogenase by α-tocopheryl succinate. Int J Biochem Cell Biol 53:409-13.Rat
Other mammals
Fat
Jelenik 2014 Diabetes2014Jelenik T, Séquaris G, Kaul K, Ouwens DM, Phielix E, Kotzka J, Knebel B, Weiß J, Reinbeck AL, Janke L, Nowotny P, Partke HJ, Zhang D, Shulman GI, Szendroedi J, Roden M (2014) Tissue-specific differences in the development of insulin resistance in a mouse model for type 1 diabetes. Diabetes 63:3856-67.MouseSkeletal muscle
Liver
Felser 2014 Toxicology I2014Felser A, Stoller A, Morand R, Schnell D, Donzelli M, Terracciano L, Bouitbir J, Krähenbühl S (2014) Hepatic toxicity of dronedarone in mice: role of mitochondrial β-oxidation. Toxicology 323:1-9.MouseLiver
Tippets 2014 BMC Cardiovasc Disord2014Tippetts TS, Winden DR, Swensen AC, Nelson MB, Thatcher MO, Saito RR, Condie TB, Simmons KJ, Judd AM, Reynolds PR, Bikman BT (2014) Cigarette smoke increases cardiomyocyte ceramide accumulation and inhibits mitochondrial respiration. BMC Cardiovasc Disord 14:165.Mouse
Rat
Heart
Other cell lines
Correa 2014 Crit Care Med2014Corrêa TD, Jeger V, Pereira AJ, Takala J, Djafarzadeh S, Jakob SM (2014) Angiotensin II in septic shock: effects on tissue perfusion, organ function, and mitochondrial respiration in a porcine model of fecal peritonitis. Crit Care Med 42:e550-9.PigHeart
Liver
Kidney
Mourier 2014 Hum Mol Genet2014Mourier A, Ruzzenente B, Brandt T, Kühlbrandt W, Larsson NG (2014) Loss of LRPPRC causes ATP synthase deficiency. Hum Mol Genet 23:2580-92.MouseHeart
Nigro 2014 Endocrinology2014Nigro M, Santos AT, Barthem CS, Louzada RA, Fortunato RS, Ketzer LA, Carvalho DP, de Meis L (2014) A change in liver metabolism but not in brown adipose tissue thermogenesis is an early event in ovariectomy-induced obesity in rats. Endocrinology 155:2881-91.RatFat
Tretter 2014 Free Radic Biol Med2014Tretter L, Horvath G, Hölgyesi A, Essek F, Adam-Vizi V (2014) Enhanced hydrogen peroxide generation accompanies the beneficial bioenergetic effects of methylene blue in isolated brain mitochondria. Free Radic Biol Med 77:317-30.Guinea pigNervous system
Suchadolskiene 2014 BMC Neurosci2014Suchadolskiene O, Pranskunas A, Baliutyte G, Veikutis V, Dambrauskas Z, Vaitkaitis D, Borutaite V (2014) Microcirculatory, mitochondrial, and histological changes following cerebral ischemia in swine. BMC Neurosci 15:2.PigNervous system
Kamath 2014 J Biol Chem2014Kamath VG, Hsiung CH, Lizenby ZJ, McKee EE (2014) Heart mitochondrial TTP synthesis and the compartmentalization of TMP. J Biol Chem 290:2034-41.RatHeart
Van Bergen 2014 Mitochondrion2014Van Bergen NJ, Blake RE, Crowston JG, Trounce IA (2014) Oxidative phosphorylation measurement in cell lines and tissues. Mitochondrion 15:24-33.Human
Mouse
Nervous system
Blood cells
Lymphocyte
Kruessel 2014 Plant Physiol2014Krüßel L, Junemann J, Wirtz M, Birke H, Thornton JD, Browning LW, Poschet G, Hell R, Balk J, Braun HP, Hildebrandt TM (2014) The mitochondrial sulfur dioxygenase ETHYLMALONIC ENCEPHALOPATHY PROTEIN1 is required for amino acid catabolism during carbohydrate starvation and embryo development in Arabidopsis. Plant Physiol 165:92-104.Plants
Davoudi 2014 PhD Thesis2014Davoudi M (2014) Effect of experimental complex III deficiency on respiratory chain assembly and function. PhD Thesis 1-65.MouseLiver
Wessels 2014 PLoS One2014Wessels B, Ciapaite J, van den Broek NMA, Nicolay K, Prompers JJ (2014) Metformin Impairs Mitochondrial Function in Skeletal Muscle of Both Lean and Diabetic Rats in a Dose-Dependent Manner. PLoS One 9:e100525.RatSkeletal muscle
Cahova 2014 Appl Physiol Nutr Metab2014Cahova M, Chrastina P, Hansikova H, Drahota Z, Trnovska J, Skop V, Spacilova J, Malinska HOliyarnyk O, Papackova Z, Palenickova E,Kazdova L (2014) Carnitine supplementation alleviates lipid metabolism derangements and protects against oxidative stress in non-obese hereditary hypertriglyceridemic rats. Appl Physiol Nutr Metab 40:280-91.RatLiver
Davoudi 2014 PLoS One2014Davoudi M, Kotarsky H, Hansson E, Fellman V (2014) Complex I function and supercomplex formation are preserved in liver mitochondria despite progressive Complex III deficiency. PLoS One 9:e86767.MouseLiver
Casanova 2014 J Nutr Biochem2014Casanova E, Baselga-Escudero L, Ribas-Latre A, Cedó L, Arola-Arnal A, Pinent M, Bladé C, Arola L, Salvadó MJ (2014) Chronic intake of proanthocyanidins and docosahexaenoic acid improves skeletal muscle oxidative capacity in diet-obese rats. J Nutr Biochem 25:1003–10.RatSkeletal muscle
Gjessing 2014 Thesis University of Tromso2014Gjessing PF (2014) Postoperative insulin resistance and the metabolic and cellular responses to single-dose preoperative oral carbohydrate supplementation. Thesis University of Tromso 102 pp.PigSkeletal muscle
Liver
Gnaiger 2014 MitoPathways2014
O2k-Protocols
Gnaiger E (2014) Mitochondrial pathways and respiratory control. An introduction to OXPHOS analysis. 4th ed. Mitochondr Physiol Network 19.12. Oroboros MiPNet Publications, Innsbruck:80 pp.
Human
Mouse
Heart
Skeletal muscle
Fibroblast
Nunez-Figueredo 2014 Brain Res Bull2014Nunez-Figueredo Y, Pardo-Andreu GL, Ramirez-Sanchez J, Delgado-Hernandez R, Ochoa-Rodriguez E, Verdecia-Reyes Y, Naal Z, Muller AP, Portela LV, Souza DO (2014) Antioxidant effects of JM-20 on rat brain mitochondria and synaptosomes: Mitoprotection against Ca2+-induced mitochondrial impairment. Brain Res Bull 109:68-76.RatNervous system
Alves-Bezerra 2014 Insect Biochem Mol Biol2014Alves-Bezerra M, Cosentino-Gomes D, Vieira LP, Rocco-Machado N, Gondim KC, Meyer-Fernandes JR (2014) Identification of uncoupling protein 4 from the blood-sucking insect Rhodnius prolixus and its possible role on protection against oxidative stress. Insect Biochem Mol Biol 50:24-33.HexapodsEndothelial;epithelial;mesothelial cell
Afshordel 2014 Prostaglandins Leukot Essent Fatty Acids2014Afshordel S, Hagl S, Werner D, Roehner N, Koegel D, Bazan NG, Eckert GP (2014) Omega-3 polyunsaturated fatty acids improve mitochondrial dysfunction in brain aging - impact of Bcl-2 and NPD-1 like metabolites. Prostaglandins Leukot Essent Fatty Acids 92:23-31.MouseNervous system
Elustondo 2014 Biochim Biophys Acta2014Elustondo PA, Negoda A, Kane CL, Kane DA, Pavlov EV (2014) Spermine selectively inhibits high-conductance, but not low-conductance calcium-induced permeability transition pore. Biochim Biophys Acta 1847:231–40.RatLiver
Hoevenaars 2014 Mol Nutr Food Res2014Hoevenaars FP, Bekkenkamp-Grovenstein M, Janssen RJ, Heil SG, Bunschoten A, Hoek-van den Hil EF, Snaas-Alders S, Teerds K, van Schothorst EM, Keijer J (2014) Thermoneutrality results in prominent diet-induced body weight differences in C57BL/6J mice, not paralleled by diet-induced metabolic differences. Mol Nutr Food Res 58:799-807.MouseSkeletal muscle
Drahota 2014 Physiol Res2014Drahota Z, Palenickova E, Endlicher R, Milerova M, Brejchova J, Vosahlikova M, Svoboda P, Kazdova L, Kalous M, Cervinkova Z, Cahova M (2014) Biguanides inhibit complex I, II and IV of rat liver mitochondria and modify their functional properties. Physiol Res 63:1-11.RatLiver
Solinas 2014 Mech Ageing Dev2014Solinas P, Fujioka H, Radivoyevitch T, Tandler B, Hoppel CL (2014) Aging effects on oxidative phosphorylation in rat adrenocortical 3 mitochondria. Mech Ageing Dev 138:10-4.RatKidney
Vigueira 2014 Cell Rep2014Vigueira PA, McCommis KS, Schweitzer GG, Remedi MS, Chambers KT, Fu X, McDonald WG, Cole SL, Colca JR, Kletzien RF, Burgess SC, Finck BN (2014) Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion. Cell Rep 7:2042-53.MouseHeart
Kidney
Ferko 2014 Physiol Res2014Ferko M, Kancirová I, Jašová M, Čarnická S, Muráriková M, Waczulíková I, Sumbalová Z, Kucharská J, Uličná O, Ravingerová T, Ziegelhöffer A (2014) Remote ischemic preconditioning of the heart: protective responses in functional and biophysical properties of cardiac mitochondria. Physiol Res 63:469-78.RatHeart
Abdurrachim 2014 Biochim Biophys Acta2014Abdurrachim D, Ciapaite J, Wessels B, Nabben M, Luiken JJ, Nicolay K, Prompers JJ (2014) Cardiac diastolic dysfunction in high-fat diet fed mice is associated with lipotoxicity without impairment of cardiac energetics in vivo. Biochim Biophys Acta 1842:1525-37.MouseHeart
Bleier 2014 Free Radic Biol Med2014Bleier L, Wittig I, Heide H, Steger M, Brandt U, Droese S4 (2014) Generator-specific targets of mitochondrial reactive oxygen species. Free Radic Biol Med 78:1-10.RatHeart
Hasenour 2014 J Biol Chem2014Hasenour CM, Ridley DE, Hughey CC, James FD, Donahue EP, Shearer J, Viollet B, Foretz M, Wasserman DH (2014) 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) effect on glucose production, but not energy metabolism, is independent of hepatic AMPK in vivo. J Biol Chem 289:5950-9.MouseLiver
Yano 2014 Nature Neurosci2014Yano H, Baranov SV, Baranova OV, Kim J, Pan Y, Yablonska S, Carlisle DL, Ferrante RJ, Kim AH, Friedlander RM (2014) Inhibition of mitochondrial protein import by mutant huntingtin. Nature Neurosci 17:822-31.MouseNervous system
Furlanetto 2014 Thesis University of Parana2014Furlanetto ALD de Matos (2014) Estresse oxidativo e transição de permeabilidade mitocondrial em células embriogênicas somáticas de Auraucária angustifolia estressadas pelo frio. Thesis University of Parana 53pp.Plants
Scandroglio 2014 Free Radic Res2014Scandroglio F, Tortora V, Radi R, Castro L (2014) Metabolic control analysis of mitochondrial aconitase: influence over respiration and mitochondrial superoxide and hydrogen peroxide production. Free Radic Res 48:684-93.RatHeart
Nervous system
Liver
Kidney
Frederick 2014 J Biol Chem2014Frederick DW, Davis JG, Dávila A Jr, Agarwal B, Michan S, Puchowicz MA, Nakamaru-Ogiso E, Baur JA (2014) Increasing NAD synthesis in muscle via nicotinamide phosphoribosyltransferase is not sufficient to promote oxidative metabolism.. J Biol Chem. 290:1546-58.MouseSkeletal muscle
Fletcher 2014 Med Sci Sports Exerc2014Fletcher JA, Meers GM, Linden MA, Kearney ML, Morris EM, Thyfault JP, Rector RS (2014) Impact of various exercise modalities on hepatic mitochondrial function. Med Sci Sports Exerc 46:1089-97.RatLiver
Cour 2014 J Cardiovasc Pharmacol Ther2014Cour M, Jahandiez V, Loufouat J, Ovize M, Argaud L (2014) Minor changes in core temperature prior to cardiac arrest influence outcomes: an experimental study. J Cardiovasc Pharmacol Ther pii:1074248414562911. 20:407-13.RabbitHeart
Nervous system
Kancirova 2014 Cardiovascular Research Supplements2014Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I. Ziegelhoffer A, Ferko M (2014) Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovascular Research Supplements 103:57–94.RatHeart
Yin 2014 J Clin Endocrinol Metab2014Yin X, Lanza IR, Swain JM, Sarr MG, Nair KS, Jensen MD (2014) Adipocyte mitochondrial function is reduced in human obesity independent of fat cell size. J Clin Endocrinol Metab 99:E209-16.HumanFat
Doerrier 2014 Life Sci2014Doerrier C, García JA, Volt H, Díaz-Casado ME, Lima-Cabello E, Ortiz F, Luna-Sánchez M, Escames G, López LC, Acuña-Castroviejo D (2014) Identification of mitochondrial deficits and melatonin targets in liver of septic mice by high-resolution respirometry. Life Sci 121:158-65.MouseLiver
Power 2014 Physiol Rep2014Power A, Pearson N, Pham T, Cheung C, Phillips A, Hickey A (2014) Uncoupling of oxidative phosphorylation and ATP synthase reversal within the hyperthermic heart. Physiol Rep pii:e12138.RatHeart
Castelein 2014 Exp Gerontol2014Castelein N, Muschol M, Dhondt I, Cai H, De Vos WH, Dencher NA, Braeckman BP (2014) Mitochondrial efficiency is increased in axenically cultured Caenorhabditis elegans. Exp Gerontol 56:26-36.Caenorhabditis elegans
Brown 2014 J Cardiovasc Pharmacol Ther2014Brown DA, Hale SL, Baines CP, del Rio CL, Hamlin RL, Yueyama Y, Kijtawornrat A, Yeh ST, Frasier CR, Stewart LM, Moukdar F, Shaikh SR, Fisher-Wellman KH, Neufer PD, Kloner RA (2014) Reduction of early reperfusion injury with the mitochondria-targeting peptide bendavia. J Cardiovasc Pharmacol Ther 19:121-32.RatHeart
Takahashi 2014 Exp Gerontol2014Takahashi K, Noda Y, Ohsawa I, Shirasawa T, Takahashi M (2014) Extended lifespan, reduced body size and leg skeletal muscle mass, and decreased mitochondrial function in clk-1 transgenic mice. Exp Gerontol 58:146-53.MouseSkeletal muscle
Liver
Cordero-Reyes 2014 J Mol Cell Cardiol2014Cordero-Reyes AM, Gupte AA, Youker KA, Loebe M, Hsueh WA, Torre-Amione G, Taegtmeyer H, Hamilton DJ (2014) Freshly isolated mitochondria from failing human hearts exhibit preserved respiratory function. J Mol Cell Cardiol 68:98-105.HumanHeart
Schiffer 2014 FASEB J2014Schiffer TA, Ekblom B, Lundberg JO, Weitzberg E, Larsen FJ (2014) Dynamic regulation of metabolic efficiency explains tolerance to acute hypoxia in humans. FASEB J 28:4303-11.HumanSkeletal muscle
Jimenez-Aranda 2014 J Pineal Res2014Jimenéz-Aranda A, Fernández-Vázquez G, Serrano MM, Reiter RJ, Agil A (2014) Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats. J Pineal Res 57:103-9.RatFat
Damiano 2014 PLoS One2014Damiano M, Gautier CA, Bulteau AL, Ferrando-Miguel R, Gouarne C, Paoli MG, Pruss R, Auchère F, L'Hermitte-Stead C, Bouillaud F, Brice A, Corti O, Lombès A (2014) Tissue- and cell-specific mitochondrial defect in Parkin- deficient mice. PLoS One 9:e99898.MouseNervous system
Iglesias-Gonzalez 2014 PhD Thesis2014Iglesias-Gonzalez J (2014) Neurotoxicity induced by oxidative stress and aluminium in relation to Parkinson’s disease: a mitochondrial bioenergetic approach by high-resolution respirometry. PhD Thesis 1-242.RatNervous system
Kiss 2014 FASEB J2014Kiss G, Konrad C, Pour-Ghaz I, Mansour JJ, Németh B, Starkov AA, Adam-Vizi V, Chinopoulos C (2014) Diaphorases provide NAD+ in anoxia. FASEB J 28:1682-97.MouseLiver
Hall 2014 Biochim Biophys Acta2014Hall A, Parhamifar L, Lange MK, Meyle KD, Sanderhoff M, Andersen H, Roursgaard M, Larsen AK, Jensen PB, Christensen C, Bartek J, Moghimi SM (2014) Polyethylenimine architecture-dependent metabolic imprints and perturbation of cellular redox homeostasis. Biochim Biophys Acta 1847:328-42.MouseLiver
Kancirova 2014 Cardiovasc Res2014Kancirova I, Jasova M, Murarikova M, Carnicka S, Sumbalova Z, Ulicna O, Vancova O, Waczulikova I, Ziegelhoffer A, Ferko M (2014) P406Adaptive changes of rat heart mitochondrial respiration: response of remote ischemic preconditioning. Cardiovasc Res 103 Suppl 1:S74-5.RatHeart
Stenberg 2014 PLoS One2014Stenberg TA, Kildal AB, Sanden E, How OJ, Hagve M, Ytrehus K, Larsen TS, Myrmel T (2014) The acute phase of experimental cardiogenic shock is counteracted by microcirculatory and mitochondrial adaptations. PLoS One 9:e105213.PigHeart
Liver
Kidney
Phielix 2014 Diabetologia2014Phielix E, Jelenik T, Nowotny P, Szendroedi J, Roden M (2014) Reduction of non-esterified fatty acids improves insulin sensitivity and lowers oxidative stress, but fails to restore oxidative capacity in type 2 diabetes: a randomised clinical trial. Diabetologia 57:572-81.HumanSkeletal muscle
Soltysinska 2014 PLoS One2014Soltysinska E, Bentzen BH, Barthmes M, Hattel H, Thrush AB, Harper ME, Qvortrup K, Larsen FJ, Schiffer TA, Losa-Reyna J, Straubinger J, Kniess A, Thomsen MB, Brüggemann A, Fenske S, Biel M, Ruth P, Wahl-Schott C, Boushel RC, Olesen SP, Lukowski R (2014) KCNMA1 encoded cardiac BK channels afford protection against ischemia-reperfusion injury. PLoS One 9:e103402.MouseHeart
Skeletal muscle
Garcia-Corzo 2014 Thesis2014García-Corzo L (2014) Fisiopatologia de la deficiencia en CoQ: evaluacion de terapias con la mitocondria como diana terapeutica. Doctoral Thesis p182.MouseHeart
Skeletal muscle
Nervous system
Kidney
Van Bree 2014 PhD Thesis2014van Bree B (2014) Mitochondria, lipotoxicity and skeletal muscle metabolism: implications for type 2 diabetes mellitus. PhD Thesis 1-150.MouseSkeletal muscle
... further results
O2k-Publications in the MiPMap

O2k-Publications: Isolated mitochondria - Abstract

Sort in ascending/descending order by a click on one of the small symbols in squares below.
 ReferenceOrganismTissue;cell
Kandel 2019 Biophys JKandel SM, Tomar N, Zheleznova N, Audi SH, Cowley Jr AW, Dash RK (2019) Calcium stimulation of mitochondrial respiration is substrate dependent and tissue specific. Biophys J.RatHeart
Kidney
De la Rosa Vargas 2019 Arch Cardiovasc DisDe la Rosa Vargas LE, Dale Abel E, Langer T, Wai T (2019) Metabolic regulation of heart failure caused by imbalanced mitochondrial dynamics. Arch Cardiovasc Dis.MouseHeart
Gnaiger 2019 NatureConferenceGnaiger E, Passrugger M, Gallee L, Felipe F Garcia-Souza, Zdrazilova L, Doerrier C (2019) High-resolution respirometry and innovations in the Oroboros O2k-technology.HumanBlood cells
HEK
Fibroblast
Platelet
Silva 2019 ESCI2019Silva FSG, Komlodi T, Garcia-Souza LF, Bento G, Doerrier C, Oliveira PJ, Gnaiger E (2019) Can fatty acid oxidation be specifically blocked by the CPT1 inhibitor etomoxir?Human
Mouse
Liver
Nickel 2018 IOC130Defects in mitochondrial calcium uptake precede defects of the respiratory chain in X-linked Barth syndrome cardiomyopathy.MouseHeart
Gnaiger 2018 AussieMitKomlodi T, Sobotka O, Doerrier C, Gnaiger E (2018) Mitochondrial H2O2 production is low under tissue normoxia but high at in-vitro air-level oxygen pressure - comparison of LEAK and OXPHOS states. AussieMit 2018 Melbourne AU.Mouse
Saccharomyces cerevisiae
Heart
Nervous system
Isola 2018 MiPschool Tromso C3
Raffaela Isola
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
MouseHeart
Komlodi 2018b EBEC2018Endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondria.MouseLiver
McMaster 2018 Am J Obstet GynecolPreeclampsia is associated with placental mitochondrial dysfunction.Human
Komlodi 2018 EBEC2018Electron supply to the Q-junction: assessment of mitochondrial respiration, H2O2 flux and the redox state of the Q-pool.MouseNervous system
Komlodi 2018 AussieMitKomlodi T, Hunger M, Moore AL, Gnaiger E (2018) Electron transfer at the Q-junction: new perspectives from combined measurement of mitochondrial O2 flux, H2O2 flux, and coenzyme Q redox state. AussieMit 2018 Melbourne AU.MouseNervous system
Fischer 2018 MiPschool Tromso E2
Christine Fischer
Analysis of mitochondrial function in iron deficiency anemia and iron overload conditions.
MouseHeart
Nervous system
Liver
Kidere 2018 MiP2018
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the effect of the mtDNA mutations on the OXPHOS system.
HumanOther cell lines
Platelet
Doerrier 2018 EBEC2018
Carolina Anneliese Doerrier
Respiratory mapping of mitochondrial pathways for establishing a database of mitochondrial physiology.
Human
Mouse
Heart
Nervous system
Blood cells
HEK
Platelet
Hoppel 2018 MiPschool Tromso D1
Charles Hoppel
Two populations of muscle mitochondria: heart and skeletal muscle.
Rat
Dog
Other mammals
Heart
Skeletal muscle
Kidere 2018 MiPschool Tromso E2
Dita Kidere
Cytoplasmic hybrid cells as a model to characterize the OXPHOS system: control sample with glutamate metabolism defect.
HumanPlatelet
Wilson 2018 Virginia TechWilson ZT, Perry JB, Brow DA (2018) High-resolution respirometry of heart mitochondria in healthy and stressed states. Virginia Tech.Heart
Meszaros 2018 EBEC2018Tissue- and substrate-specific patterns in the oxygen kinetics of mitochondrial respiration.MouseHeart
Liver
Nervous system
Doerrier 2018 MiP2018b
Carolina Doerrier
Evaluation of anaplerotic pathways to avoid artefacts in respirometric measurement of fatty acid oxidation.
Human
Mouse
Blood cells
HEK
Heart
Nervous system
Platelet
Meszaros 2018 Mitochondrial Medicine 2018 Hinxton UKHigh-resolution mitochondrial oxygen kinetics as diagnostic tool in complex IV impairments.MouseHeart
Nervous system
Liver
Dubouchaud 2018 MiPschool Tromso
Dubouchaud Herve
AMPK deficiency elicits changes in OXPHOS in heart mitochondria.
MouseHeart
Volska 2018 MiP2018
Kristina Volska
The mechanisms of long-chain acylcarnitine accumulation during ischemia.
Heart
Pereira da Silva Grilo da Silva 2018 MiP2018
Filomena Pereira da Silva Grilo da Silva
The unspecific effect of etomoxir on mitochondrial respiration.
Human
Mouse
Nervous system
Liver
Other cell lines
Kappler 2018 J Lab MedKappler L, Hoene M, Kollipara L, Li J, Hu C, van Törne C, Hauck S, Irmler M, Beckers J, de Angelis MH, Peter A, Xu G, Häring H, Weigert C, Sickmann A (2018) Systems medicine approach combining Multi-omics and functional analyses in hepatic and skeletal muscle mitochondria of pre-diabetic mice. J Lab Med.MouseSkeletal muscle
Liver
Pchelin 2018 IOC130Activation of heterodimeric receptor to erythropoietin with its agonist CdEPO regulates brain mitochondrial bioenergetics after local acute ischemia/reperfusion in C57BL/6 mice.MouseNervous system
Ravasz 2018 Abstract The evolving concept of mitochondriaVast pools of endogenous quinones sustain NADH oxidation by Complex I during anoxia, supporting substrate-level phosphorylation in mouse liver mitochondriaMouseLiver
Sobotka 2018 MiP2018
Ondrej Sobotka
Measurement of ROS production under hypoxia and unexpected methodological pitfalls of Amplex UltraRed assay.
Mouse
Saccharomyces cerevisiae
Heart
Nervous system
Belosludtsev 2018 MiP2018
MiPsociety
Effect of bedaquiline and delamanid on the functions of rat liver mitochondria.
RatLiver
Kovalev 2018 EMBSKovalev A, Sokolova I, Sukhotin A (2018) Allometry of mitochondrial respiration in mussels. EMBS.MolluscsLiver
Islet cell;pancreas;thymus
Fromme 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Source depot and dietary status influence oxidative phosphorylation capacity in permeabilized, mature adipocytes. Fromme_Presentation
MouseFat
Doerrier 2017 MiP2017 C1
Carolina Anneliese Doerrier
Effects of warm ischemia on cardiac mitochondria to detect specific targets by high-resolution respirometry (HRR)
MouseHeart
Vaka 2017 HypertensionAbstract P265: Placental ischemia causes renal mitochondrial impairment in reduced uterine perfusion pressure rats.RatKidney
Genital
Doerrier 2017 Abstract MitoEAGLE Barcelona
COST Action MitoEAGLE
SUIT reference protocol for comparative mitochondrial physiology.
Human
Mouse
Heart
Nervous system
HEK
Scatena 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Mitochondria and cancer stem cells in hepatocarcinoma. An illustrative example of a tangled methodological approach.
Liver
Komlodi 2017 MiP2017
Timea Komlodi
H2O2 production under hypoxia in brain and heart mitochondria: does O2 concentration matter?
MouseHeart
Nervous system
Endlicher 2017 MiP2017
Rene Endlicher
Age-related changes in isolated mitochondria from rat liver.
RatLiver
Amick 2017 MiPschool Obergurgl
Amick picture.jpg
Bioenergetic profiling of mitochondria isolated from three distinct brain regions relevant to AD pathology in non-human primates.
Other mammalsNervous system
Shabalina 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Control of UCP1 activity in brown fat mitochondria.
MouseFat
Meszaros 2017 MiP2017
Andras Meszaros
Mitochondrial oxygen kinetics as a sensitive diagnostic tool to determine apparent cytochrome c oxidase excess capacity.
MouseNervous system
Liver
Kidney
Brazdova 2017 MiP2017
Brazdova Andrea
Pleiotropic effects of biguanides on mitochondrial reactive oxygen species production.
Fat
Meszaros 2017 MiPschool Obergurgl
Andras Meszaros
(Very) High-resolution respirometry – a deep dive into oxygen dependence of mitochondrial respiration.
MouseLiver
Nervous system
Kidney
Sobotka 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
The effect of 24 weeks of high-fat and high-cholesterol diet on rat liver mitochondria. Sobotka_Presentation
RatLiver
Nedergaard 2017 MiP2017
Jan Nedergaard
Creatine effect in mitochondria from different tissues.
MouseHeart
Liver
Fat
Klepinin 2017 MiP2017
MiPsociety
Novel method to study the role of the adenylate kinase network in health and disease.
Human
Rat
Heart
Stem cells
Komlodi 2017 MiPschool Obergurgl
Timea Komlodi
Electron pressure exerted by convergent succinate- and glycerophosphate-pathways to the Q-junction regulate reversed electron transfer to Complex I and H2O2 production.
MouseNervous system
Arandarcikaite 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Age-related responses of brain mitochondria to ischemic insult. Arandarcikaite_Presenation
RatNervous system
Sobotka 2017 MiP2017
Ondrej Sobotka
Metabolic changes in rat liver mitochondria during the development of liver steatosis.
RatLiver
Komlodi 2017 Abstract MITOEAGLE Barcelona
COST Action MitoEAGLE
Succinate dehydrogenase regulation via oxaloacetate in brain mitochondria.
Guinea pig
Mouse
Nervous system
Kidney
Heart
Liver
Shabalina 2017 MiP2017
Irina Shabalina
In UCP1-ablated mice, prolonged cold exposure promotes mitochondrial dysfunction, apoptosis and inflammation in brown adipose tissue, and accumulation of visceral obesogenic fat.
MouseFat
Doerrier 2017 MiPschool C2
DoerrierC.JPG
Substrate-uncoupler-inhibitor titration (SUIT) protocols – fundamental principles.
Human
Mouse
Heart
Nervous system
HEK
Aasum 2017 Abstract MITOEAGLE Barcelona
COST Action MITOEAGLE
Mitochondrial function in the diabetic heart – effect of an acute fat-load.
MouseHeart
Schilling 2017 J Mol Cell CardiolLoss of caveolin-1 alters cardiac mitochondrial function and increases susceptibility to stress.MouseHeart
Sobotka 2016 Abstract IOC116Sobotka O, Kucera O, Stankova P, Endlicher R, Nozickova K, Banni A, Cervinkova Z (2016) Mitochondrial respiration in fatty liver. Mitochondr Physiol Network 21.11RatLiver
Komlodi 2016 Abstract IOC116Komlodi T, Geibl F, Sassani M, Adam-Vizi V, Tretter L (2016) The effect of ΔΨmt and ΔpH on mitochondrial reactive oxygen species production - A comparative study using mitochondria isolated from different mammalian tissues. Mitochondr Physiol Network 21.11Guinea pigHeart
Skeletal muscle
Nervous system
Chicco 2016a Abstract MitoFit Science Camp 2016Oxygen dependence of H2O2 release from skeletal muscle and cardiac mitochondria: influence of sample preparation.MouseHeart
Skeletal muscle
Garcia-Souza 2016 Abstract Mito Xmas Meeting InnsbruckAssessment of fatty acid oxidation in mouse brain and liver mitochondria.Nervous system
Liver
Hoppel 2016b Abstract MitoFit Science Camp 2016Comparison of permeabilized skeletal muscle fibers or isolated mitochondria for the detection of oxidative phosphorylation defects.HumanSkeletal muscle
Doerrier 2016b Abstract Mito Xmas Meeting InnsbruckSearching for specific targets of ischemic damage of cardiac mitochondria using O2k-Fluorometry.MouseHeart
Krumschnabel 2016a Abstract MitoFit Science Camp 2016O2k-Protocols: Mitochondrial preparations for HRR.MouseHeart
Doerrier 2016 Abstract MitoFit Science Camp 2016Development of a SUIT reference protocol for OXPHOS analysis by high-resolution respirometry.Human
Mouse
Heart
Blood cells
HEK
Platelet
Ojuka 2015 Abstract MiPschool Cape Town 2015Use of malate or carnitine as co-substrates for assessment of fatty acid oxidation.
Sumbalova 2015 Abstract MiP2015High-resolution measurement of mitochondrial membrane potential and respiration – comparison of potentiometric and fluorometric methods.MouseNervous system
Hill 2015 Abstract MiPschool London 2015A novel inhibitor of the mitochondrial permeability transition pore is beneficial in an experimental model of multiple sclerosis.MouseLiver
Brown 2015 Abstract MiPschool Cape Town 2015Protection of post-ischemic mitochondrial bioenergetics by targeting cardiolipin-dependent membrane fluidity.RatHeart
Doerrier 2015 Abstract MiPschool Greenville 2015"Succinate paradox" study by high resolution respirometry combined with fluorometry and spectrofluorometry: NextGen-O2k.MouseHeart
Gnaiger 2015 Abstract MiPschool Cape Town 2015The functional design of the electron transfer system (ETS) and mitochondrial respiratory control.
Rohlena 2015 Abstract MiP2015Ubiquinone-binding site mutagenesis reveals the role of mitochondrial complex II in cell death initiation.HumanOther cell lines
Laner 2015 Abstract MiPschool Cape Town 2015The Oroboros Oxygraph-2k for high-resolution respirometry and O2k-Fluorometry: a new quality in OXPHOS analysis.Mouse
Saccharomyces cerevisiae
Heart
Kaambre 2015 Abstract MiP2015Quantitative characterization of respiratory parameters of human colorectal and breast cancer clinical material.HumanEndothelial;epithelial;mesothelial cell
Maarman 2015 Abstract MiPschool Cape Town 2015Characterisation of mitochondrial function in a model of pulmonary hypertension-induced right ventricular failure.RatHeart
Doerrier 2015 Abstract MiP2015Simultaneous measurement of mitochondrial respiration, hydrogen peroxide production, and NADH autofluorescence to assess mitochondrial function.MouseHeart
Sumbalova 2014 Abstract MiP2014Optimization of malate concentration for high-resolution respirometry: mitochondria from rat liver and brain.RatNervous system
Liver
Borutaite 2014 Abstract MiP2014Controversies regarding cytochrome c test for mitochondrial membrane integrity.RatHeart
Nervous system
Krumschnabel 2014 Abstract MiP2014Simultaneous high-resolution measurement of mitochondrial respiration and hydrogen peroxide production.MouseNervous system
Harrison 2014 Abstract MiP2014The relationship between cytochrome redox state and oxygen consumption in isolated mouse and beef heart mitochondria during hypoxia.Rat
Bovines
Heart
Tretter 2014 Abstract MiP2014Cool or heat? Bioenergetic and ROS homeostatic approach to therapeutic hypothermia.Guinea pigNervous system
MacDonald 2014 Abstract MiP2014The mitochondrial enzyme 4-hydroxy-2-oxoglutarate aldolase (HOGA) – involvement in the TCA cycle.RatHeart
Nervous system
Liver
Kidney
Herbst 2014 Abstract MiP2014Analysis of mitochondrial function in multiple brain regions through in situ permeabilization.MouseNervous system
Sobotka 2014 Abstract IOC95Sobotka O (2014) Effect of α-Tocopheryl succinate on Complex II. Mitochondr Physiol Network 19.10RatHeart
Liver
Meszaros 2014 Abstract MiP2014Methodological aspects of assessing mitochondrial function in small intestinal mucosal samples of rats and guinea pigs.Rat
Guinea pig
Legkun 2014 Abstract IOC 2014-04 SchroeckenLegkun G, Motovilov K (2014) Investigation on alternative mechanism of electron transport in the respiratory system. Mitochondr Physiol Network 19.02.RatLiver
Houghton 2014 Abstract MiP2014The effect of bioactive phenolics on chronic mitochondrial stress associated with the onset of diabetes.HumanLiver
Doerrier 2014 Abstract SECFEvaluation of melatonin treatment in mitochondria of permeabilized myocardial fibers from septic mice.MouseHeart
Power 2014 Abstract MiP2014The hot heart: cardiac mitochondrial energetics during hyperthermia.RatHeart
Agrimi 2014 Abstract IOC 2014-04 SchroeckenAgrimi G, Mena MC, Izumi K, Pisano I, Germinario L, Fukuzaki H, Palmieri L, Blank LM, Kitagaki H (2014) Increased mitochondrial pyruvate dissimilation in sake yeast. Mitochondr Physiol Network 19.02.Saccharomyces cerevisiae
Jezek 2014 Abstract MiP2014Mitochondrial cristae morphology changes: from Hackenbrock to hypoxia.Other cell lines
Luna-Sánchez 2014 Abstract SECFMitochondrial encephalopathy due to coenzyme q deficiency: pathogenesis and treatment.Mouse
Figueira 2014 Abstract MiP2014Mitochondrial respiration and calcium transport in rat tissues: conversely from skeletal muscle, heart and brain, isolated liver mitochondria exhibit gender dimorphism in respiratory activity.RatHeart
Skeletal muscle
Nervous system
Liver
Wagenaars 2014 Abstract IOC 2014-04 SchroeckenWagenaars J, Willems PHGM, Koopman WJ (2014) Oxygen consumption in OXPHOS-deficient cells. Mitochondr Physiol Network 19.02.Human
Mouse
Skeletal muscle
Fibroblast
Komlodi 2014 Abstract MiP2014Methylenblue, an enhancer of mitochondrial substrate-level phosphorylation.Guinea pigNervous system
Galina 2014 Abstract MiP2014Effects of perinatal asphyxia in mitochondria of brain during development of the central nervous system.RatNervous system
Brandt 2013 Abstract MiP2013Brandt T, Mourier A, Stewart JB, Larsson NG, Kühlbrandt W (2013) Structure and function of aged mouse mitochondria. Mitochondr Physiol Network 18.08.MouseHeart
Liver
Kidney
Vercesi 2013 Abstract MiP2013Vercesi AE (2013) Mitochondrial respiration, Ca2+ transport and oxidative stress: Fungi, trypanosomes, plants and mammals. Mitochondr Physiol Network 18.08.Rat
Other invertebrates
Fungi
Plants
Protists
Heart
Persson 2013 Abstract MiP2013Persson P, Palm F, Friederich-Persson M (2013) The effects of Angiotensin II on mitochondrial respiration: A role of normoglycemia versus hyperglycemia. Mitochondr Physiol Network 18.08.RatKidney
Hendricks 2013 Abstract MiP2013Hendricks E, Nathan BP, Menze MA (2013) Bioenergetics of permeabilized and intact nerve cell terminals from ApoE deficient and wild type mice. Mitochondr Physiol Network 18.08.MouseNervous system
Chicco 2013 Abstract MiP2013 PosterChicco AJ, Claiborne MS, Le CH, Mulligan CM (2013) Remodeling of skeletal muscle mitochondria in response to exercise training in taz shRNA mouse model of human Barth Syndrome. Mitochondr Physiol Network 18.08.MouseSkeletal muscle
Scott 2013 Abstract MiP2013Scott GR, Mahalingam S, McClelland GB(2013) Mitochondrial adaptations to hypoxia in high-altitude birds and mammals. Mitochondr Physiol Network 18.08.Other mammals
Birds
Skeletal muscle
Dungel 2013 Abstract MiP2013Dungel P, Perlinger M, Faulhammer B, Weidinger A, Redl H, Kozlov AV (2013) Iron-mediated injury of mitochondria is attenuated by nitrite. Mitochondr Physiol Network 18.08.RatLiver
Gellerich 2013 Abstract MiP2013Gellerich FN, Korzeniewski B, Gizatullina Z, Debska-Vielhaber G, Gainutdinov T, König R, Reymann K, Vielhaber S(2013) The mitochondrial gas pedal, a unique property of neurons exists also in heart and skeletal muscle but not in astrocytes. New evidences by in silico investigations and (patho-)physiological consequences. Mitochondr Physiol Network 18.08.Nervous system
Palm 2013 Abstract MiP2013Palm F, Hansell P, Friederich-Persson M (2013) Role of mitochondrial function for the onset and progression of kidney disease. Mitochondr Physiol Network 18.08.Mouse
Rat
Kidney
Kallijarvi 2013 Abstract IOC75Kallijarvi J (2013) Respiratory chain dysfunction in the Complex III assembly disorder GRACILE. Mitochondr Physiol Network 18.03.Human
Mouse
Liver
Kidney
Fibroblast
Christen 2013 Abstract MiP2013Christen F, Desrosiers V, Blier PU (2013) Thermal sensitivity of mitochondria from arctic charr heart: Mitochondrial respiration and ROS production. Mitochondr Physiol Network 18.08.Fishes
Other mammals
Heart
Ortiz 2013 Abstract SEORMolecular Basis of the radiotherapy-induced mucositis, beneficial effects of melatonin.Rat
Prouteau-Angebault 2013 Abstract IOC75Prouteau-Angebault C (2013) Are cardiolipins involved in the mitochondrial respiratory chain defect in OPA1 mouse model? Mitochondr Physiol Network 18.03.MouseSkeletal muscle
Nervous system
Jezek 2013 Abstract MiP2013Ježek P, Ježek J, Zelenka J, Dlasková A, Jabůrek M (2013) Antioxidant synergy of mitochondrial uncoupling protein UCP2 and phospholipase iPLA2γ. Mitochondr Physiol Network 18.08.MouseLung;gill
Islet cell;pancreas;thymus
Galina 2013 Abstract MiP2013Galina A, Messeder DJM, Camacho-Pereira J, Pereira da Silva AP, Rodrigues-Ferreira C (2013) Effects of antitumor alkylating agent 3-bromopyruvate on energy transducing pathways in hepatoma HepG2, liver mitochondria and SERCA: Is there any role for mitochondrial hexokinase activity? Mitochondr Physiol Network 18.08.RatSkeletal muscle
Nervous system
Liver
Other cell lines
Tretter 2013 Abstract MiP2013Tretter L, Komlódi T, Ádám-Vizi V (2013) The effects of methylmalonic acid on alpha-ketoglutarate supported oxidation in isolated brain, heart and liver mitochondria. Mitochondr Physiol Network 18.08.Guinea pigHeart
Nervous system
Liver
Slinde 2013 Abstract MiP2013Slinde E, Egelandsdal B, Olsen RE (2013) Respiration of tissue and mitochondria from Atlantic salmon (Salmo salar, L) liver, muscle, heart, brain and blood. Mitochondr Physiol Network 18.08.Other mammals
Fishes
Heart
Liver
Blood cells
Friederich-Persson 2013 Abstract MiP2013Friederich-Persson M, Hansell P, Wilcox CS, Palm F (2013) Potassium controls rat mitochondrial function: In vivo and in vitro considerations. Mitochondr Physiol Network 18.08.RatHeart
Kidney
Camacho-Pereira 2013 Abstract IOC75Camacho-Pereira J (2013) CD38 as a regulator of mitochondrial function. Mitochondr Physiol Network 18.03.MouseHEK
Liver
Macrophage-derived
Hand 2013 Abstract MiP2013Hand SC, Patil Y (2013) Defense against ATP depletion during the energy-limited state of diapause. Mitochondr Physiol Network 18.08.Artemia
Crustaceans
Kressig 2013 Abstract IOC79Kressig F (2013) et al. Mechanism of increased pulmonary vascular remodeling in UCP2 k/o mice. Mitochondr Physiol Network 18.07MouseLung;gill
Other cell lines
Arandarcikaite 2013 Abstract MiP2013Arandarcikaite O, Borutaite V (2013) The protective effect of NO against ischemia induced brain mitochondrial injury. Mitochondr Physiol Network 18.08.RatNervous system
Staples 2013 Abstract MiP2013Staples JF(2013) Mechanisms of mitochondrial metabolic suppression in hibernation. Mitochondr Physiol Network 18.08.Other mammalsLiver
Larsen FJ 2013 Abstract MiP2013Larsen FJ, Schiffer TA, Lundberg JO, Weitzberg E (2013) Human mitochondria has a unique response to ischemia-reperfusion injury compared to mitochondria from rat, mouse and pig . Mitochondr Physiol Network 18.08.Human
Pig
Mouse
Rat
Kozlov 2013 Abstract MiP2013Kozlov AV, Paier-Pourani J, Weidinger A, Dungel P, Redl H, Duvigneau C (2013) Regulatory role of mitochondrial ROS upon inflammation. Mitochondr Physiol Network 18.08.RatLiver
Schulte 2013 Abstract MiP2013Chung DJ, Schulte PM, Richards JG (2013) The effect of low-temperature acclimation on mitochondrial function in the common killifish (Fundulus heteroclitus), a top-down elasticity analysis. Mitochondr Physiol Network 18.08.FishesLiver
Skulachev 2013 Abstract MiP2013Skulachev VP (2013) SkQ1, the first mitochondria-targeted medicine available in drugstores. Mitochondr Physiol Network 18.08.Human
Mouse
Horse
Dog
Rabbit
Fishes
Other invertebrates
Fungi
Plants
Heart
Skeletal muscle
Nervous system
Kidney
Islet cell;pancreas;thymus
Other cell lines
HeLa
Fibroblast
Stem cells
Borutaite 2013 Abstract MiP2013Borutaite V, Jablonskiene G, Arandarcikaite O (2013) Mitochondrial response to heart and brain ischemia. Mitochondr Physiol Network 18.08.Pig
Rat
Heart
Nervous system
Szibor 2013 Abstract MiP2013Szibor M, Heidler J, Gizatullina Z, Salwig I, Dhandapani PK, Wittig I, Rustin P (2013) Expression of Ciona intestinalis alternative oxidase in mouse. Mitochondr Physiol Network 18.08.MouseHeart
Skeletal muscle
Nervous system
Liver
Lung;gill
Lindenberg 2013 Abstract MiP2013Lindenberg K, Matallo J, Fleischer C, Lenk T, Lehnert S, Jahn O, Otto M, Calzia E, Landwehrmeyer GB (2013) Similar alterations in mitochondrial proteome of brain and skeletal muscle in two transgenic mouse models for Huntington´s disease. Mitochondr Physiol Network 18.08.MouseSkeletal muscle
Nervous system
Menze 2013 Abstract MiP2013Menze MA, Marunde MA, Samarajeewa DA, Anderson J, Li S, Hand SC (2013) Group1 LEA protein ameliorates inhibition of mitochondrial respiration in Drosophila melanogaster Kc167 cells and isolated mitochondria. Mitochondr Physiol Network 18.08.Drosophila
Artemia
Crustaceans
Hexapods
Other cell lines
CHO
HEK
Macrophage-derived
Bir 2013 Abstract MiP2013Bir A, Sen O, Anand S, Banerjee P, Sahoo A, Khemka V, Cappai R, Chakrabarti S (2013) α-Synuclein mediated alterations in mitochondrial oxidative phosphorylation system: Implications in the pathogenesis of Parkinson’s disease. Mitochondr Physiol Network 18.08.RatNervous system
Other cell lines
Chicco 2013 Abstract IOC79Chicco AJ (2013) Substrate-specific impairment of oxidative phosphorylation in Tafazzin-deficient cardiac mitochondria: potential role of CoA deficiency. Mitochondr Physiol Network 18.07MouseHeart
Sumbalova 2012 Abstract BioblastSumbalova Z, Fasching M, Gnaiger E (2012) Evaluation of mitochondrial respiration and membrane potential in mouse brain homogenate. Mitochondr Physiol Network 17.12:61.MouseNervous system
Cervinkova 2012 Abstract BioblastCervinkova Z, Stankova P, Cervinka M, Kucera O, Drahota Z (2012) Evaluation of mitochondrial functions – an important tool for experimental hepatology. Mitochondr Physiol Network 17.12.RatLiver
Dzialowski 2012 Abstract IOC72Dzialowski EM, Sirsat T, Goy S (2012) T3: Does it really make the alligator go “Tick, Tock”? Mitochondr Physiol Network 17.13.ReptilesHeart
Skeletal muscle
Watala 2012 Abstract BioblastWatala C, Przygodzki T, Siewiera K, Kassassir H, Talar M, Labieniec-Watala M (2012) Oxygen consumption in resting and activated blood platelets: platelet mitochondria and cyclooxygenases as compounding targets for high-resolution respirometry. Mitochondr Physiol Network 17.12.Human
Rat
Endothelial;epithelial;mesothelial cell
Blood cells
Platelet
Hoppel 2012 Abstract BioblastHoppel CL (2012) Mitochondrial functional testing – muscle biopsy, isolated mitochondria and others. Mitochondr Physiol Network 17.12.HumanSkeletal muscle
Liver
Kamath 2012 Abstract IOC72Kamath VG, Lizenby ZJ, Adusumilli VRKR, Hsiung CH, McKee EE (2012) Measuring mitochondrial OXPHOS as a nucleoside reverse transcriptase inhibitor induced cardiac toxicity endpoint. Mitochondr Physiol Network 17.13.Rat
Kiss 2012 Abstract BioblastKiss G, Konrad C, Doczi J, Starkov AA, Kawamata H, Manfredi G, Zhang SF, Gibson GE, Beal MF, Adam-Vizi V, Chinopoulos C (2012) The negative impact of alpha-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation. Mitochondr Physiol Network 17.12.MouseNervous system
Liver
Koziel 2012 Abstract BioblastKoziel R, Pircher H, Kratochwil M, Lener B, Hermann M, Dencher N.A, Jansen-Durr P (2012) NADPH oxidase Nox4 induces mitochondrial dysfunction in human endothelial cells. Mitochondr Physiol Network 17.12.HUVEC
Konrad 2012 Abstract BioblastKonrad C, Kiss G, Torocsik B, Adam-Vizi V, Chinopoulos C (2012) Absence of Ca2+-induced mitochondrial permeability transition but presence of bongkrekate-sensitive nucleotide exchange in C. crangon and P. serratus. Mitochondr Physiol Network 17.12.Artemia
Crustaceans
Lund 2012 Abstract IOC68Lund J, Hafstad AD, Hagve M, Larsen TS, Aasum E (2012) High intensity exercise prevents impairment of respiratory capacity in cardiac mitochondria from obese mice. MiPNet17.08.MouseHeart
Mark 2012 Abstract BioblastMark FC, Strobel A, Poertner HO (2012) Ocean warming and acidification – when fish mitochondria turn sour. Mitochondr Physiol Network 17.12.FishesHeart
Liver
Labieniec-Watala 2012 Abstract BioblastLabieniec-Watala M, Siewiera K, Watala C (2012) Seasonal fluctuations affect the physiology of laboratory animals – facts and artifacts from the perspective of heart mitochondrial respiratory response to tested compounds. Mitochondr Physiol Network 17.12.Mouse
Rat
Heart
Liver
Fibroblast
Acuna-Castroviejo 2012 Abstract BioblastAcuna-Castroviejo D (2012) Melatonin and the quality of life: the melatonin-mitochondrion connection. Mitochondr Physiol Network 17.12.Mouse
Rat
Heart
Skeletal muscle
Nervous system
Liver
Hepple 2012 Abstract BioblastHepple RT, Picard M, Taivassalo T (2012) Is latent mitochondrial dysfunction in aging muscle exposed through mitochondrial isolation? Mitochondr Physiol Network 17.12.Skeletal muscle
Pinho 2011 Abstract IOC65Pinho JPC, Goncalves RL, Oliveira MF (2011) Studies on the dynamic changes of mitochondrial function following a blood meal in the kissing bug Rhodnius prolixus. MiPNet16.03.Hexapods
Fasching 2011 Abstract BerlinFasching M, Harrison DK, Tretter L, Gnaiger E (2011) Combination of high-resolution respirometry and fluorometry for continuous monitoring of hydrogen peroxide production by mitochondria with resolution in the nanomolar range. Abstract Berlin.MouseNervous system
Sumbalova 2011 Abstract Mitochondrial MedicineSumbalova Z, Fasching M, Gnaiger E (2011) Substrate control in mitochondrial respiration and regulation of mitochondrial membrane potential. Abstract Mitochondrial Medicine Chicago.MouseNervous system
Nuskova 2011 Abstract IOC61Nuskova H, Pecina P, Kovarova N, Dell’Agnello C, Zeviani M, Houstek J (2011) Cytochrome c oxidase with decreased H+/e− ratio in SURF1 knockout mice. MiPNet16.01.MouseEndothelial;epithelial;mesothelial cell
Fibroblast
Rosca MiP2010Rosca MG, Hoppel CL (2010) Activation of distinct mitochondrial cAMP-PKA compartments induces different effects on mitochondrial function.RatHeart
Gnaiger Abstract MiP2010 2-01Gnaiger E (2010) Measuring the upper limit of mitochondrial performance - how and why?HumanFibroblast
Rosenfeld 2010 Abstract IOC60Rosenfeld E (2010) Abstract IOC60. MiPNet15.10.Saccharomyces cerevisiae
Fungi
Protists
ElBacha 2010 Abstract IOC60El-Bacha T, Abud M, Galina A, Da Poian AT (2010) Bioenergetics of liver mitochondria from mice infected with Dengue virus. MiPNet15.10.MouseLiver
Friedrich 2010 Abstract MiP2010Kidney cortex mitochondria are non-functional in a potassium-based media whereas heart mitochondria improve with increasing potassium concentration. Mitochondr Physiol Network 15.6.RatHeart
Kidney
Other cell lines

mt-Preparations

 »O2k-Publications:_Topics#Preparations