FI Helsinki Mervaala E

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FI Helsinki Mervaala E

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Institute of Biomedicine, Pharmacology

Biomedicum Helsinki

University of Helsinki

Address P.O. BOX 63

Haartmaninkatu 8, FI-00014

City Helsinki
State/Prov
Country Finland
Weblink
Contact Mervaala Eero
Team Bechara-Hirvonen Nada, Kallijaervi Jukka, Kankuri Esko, Lapatto Risto, Purhonen Janne
Team previous
Status O2k 2011-
Oroboros Events IOC100, MiP2014, IOC93, IOC75
Topics


O2k-Publications

 PublishedReference
Rajendran 2019 EMBO Mol Med2019Rajendran J, Purhonen J, Tegelberg S, Smolander OP, Mörgelin M, Rozman J, Gailus-Durner V, Fuchs H, Hrabe de Angelis M, Auvinen P, Mervaala E, Jacobs HT, Szibor M, Fellman V, Kallijärvi J (2019) Alternative oxidase-mediated respiration prevents lethal mitochondrial cardiomyopathy. EMBO Mol Med 11:e9456.
Tegelberg 2017 Orphanet J Rare Dis2017Tegelberg S, Tomašić N, Kallijärvi J, Purhonen J, Elmér E, Lindberg E, Nord DG, Soller M, Lesko N, Wedell A, Bruhn H, Freyer C, Stranneheim H, Wibom R, Nennesmo I, Wredenberg A, Eklund EA, Fellman V (2017) Respiratory chain complex III deficiency due to mutated BCS1L: a novel phenotype with encephalomyopathy, partially phenocopied in a Bcs1l mutant mouse model. Orphanet J Rare Dis 12:73.
Nelskylae 2017 Resuscitation2017Nelskylä A, Nurmi J, Jousi M, Schramko A, Mervaala E, Ristagno G, Skrifvars MB (2017) The effect of 50% compared to 100% inspired oxygen fraction on brain oxygenation and post cardiac arrest mitochondrial function in experimental cardiac arrest. Resuscitation 116:1-7.
Raesaenen 2016 Proc Natl Acad Sci U S A2016Räsänen M, Degerman J, Nissinen TA, Miinalainen I, Kerkelä R, Siltanen A, Backman JT, Mervaala E, Hulmi JJ, Kivelä R, Alitalo K (2016) VEGF-B gene therapy inhibits doxorubicin-induced cardiotoxicity by endothelial protection. Proc Natl Acad Sci U S A 113:13144-49.
Heinonen 2016 Hum Exp Toxicol2016Heinonen JA, Schramko AA, Skrifvars MB, Litonius E, Backman JT, Mervaala E, Rosenberg PH (2016) The effects of intravenous lipid emulsion on hemodynamic recovery and myocardial cell mitochondrial function after bupivacaine toxicity in anesthetized pigs. Hum Exp Toxicol 36:365-75.
Nissinen 2016 Sci Rep2016Nissinen TA, Degerman J, Räsänen M, Poikonen AR, Koskinen S, Mervaala E, Pasternack A, Ritvos O, Kivelä R, Hulmi JJ (2016) Systemic blockade of ACVR2B ligands prevents chemotherapy-induced muscle wasting by restoring muscle protein synthesis without affecting oxidative capacity or atrogenes. Sci Rep 6:32695.
Kivelae 2014 EMBO Mol Med2014Kivelä R, Bry M, Robciuc MR, Räsänen M, Taavitsainen M, Silvola JM, Saraste A, Hulmi JJ, Anisimov A, Mäyränpää MI, Lindeman JH, Eklund L, Hellberg S, Hlushchuk R, Zhuang ZW, Simons M, Djonov V, Knuuti J, Mervaala E, Alitalo K (2016) VEGF-B-induced vascular growth leads to metabolic reprogramming and ischemia resistance in the heart. EMBO Mol Med 6:307-21.
Den Hollander 2014 Toxicol Sci2014den Hollander B, Sundström M, Pelander A, Ojanperä I, Mervaala E, Korpi ER, Kankuri E (2014) Keto amphetamine toxicity - focus on the redox reactivity of the cathinone designer drug mephedrone. Toxicol Sci 141:120-31.

O2k-Abstracts

update please

Feedback

  • I was participating last summer in WorldPharma 2010 congress in Copenhagen and heard a fantastic presentation given by Professor Sir Salvador Moncada about mitochondrial function measured by OROBOROS Oxygraph. - Eero Mervaala (2010)