Larsen 2023 MiP2023

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Larsen 2023 MiP2023


Larsen Steen
Mitochondrial adaptations to weight loss – lifestyle, surgery or medication.

Link: MiP2023 Obergurgl AT

Larsen Steen (2023)

Event: MiP2023 Obergurgl AT

Weight loss maintenance after lifestyle changes (diet and exercise) is challenging and unfortunately the success rate is low. This topic has received major attention and yet the explanation behind the apparent inability to maintain lifestyle changes remains unresolved. Combining increased physical activity and changes of the diet composition are typically first line of treatment to achieve weight loss, but gastric bypass surgery is also used for weight loss. Different drugs are on the market that induces a weight loss.
The presentation will focus on mitochondrial adaptations after a weight loss induces by lifestyle changes or after gastric bypass surgery. We have conducted two clinical trials investigating weight loss after a lifestyle intervention or after gastric bypass surgery, with a focus on mitochondrial function in skeletal muscle and adipose tissue. Furthermore focus will also be on the effect of different weight loss medications and how these affects mitochondrial function.

Affiliation

University of Copenhagen, DK
stelar@sund.ku.dk


β€’ O2k-Network Lab: DK Copenhagen Larsen S


Labels: MiParea: Exercise physiology;nutrition;life style 


Organism: Human  Tissue;cell: Skeletal muscle, Fat 




Event: Oral 


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