Westphal 2017 US Patent

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Westphal S, Fromme T, Klingenspor M (2017) Fgf-8 for use in treating diseases or disorders of energy homeostasis. US Patent US20170258874 A1.

» Open Access

Westphal S, Fromme T, Klingenspor M (2017) US Patent

Abstract: The present invention relates to polypeptides for use in treating diseases or disorders of energy homeostasis such as obesity, dyslipidemia, diabetes, insulin resistance, hyperglycemia or the metabolic syndrome. The invention also relates to polynucleotides encoding said polypeptides for use in treating diseases or disorders of energy homeostasis. Also provided by the present invention are pharmaceutical compositions comprising said polypeptides and polynucleotides for use in treating diseases or disorders of energy homeostasis. Said polypeptides, polynucleotides and pharmaceutical compositions may be administered locally, in particular locally into the visceral adipose tissue. Another aspect of the invention relates to a cosmetic product and the use of said cosmetic product for reducing body weight, in particular for reducing abdominal adipose tissue.


Bioblast editor: Kandolf G O2k-Network Lab: DE Freising Klingenspor M


Labels: MiParea: Respiration, Pharmacology;toxicology  Pathology: Diabetes, Obesity 

Organism: Mouse 

Preparation: Homogenate 



HRR: Oxygraph-2k 

Labels, 2018-02