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Latest revision as of 08:52, 27 May 2024

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-» A future for Ukraine is the future of its science

2024 Week 22

May-27 Mo

Same experimental conditions, but different O₂ fluxes in the left and right chambers?

Check for instrumental and operational factors that could be causing O₂ flux differences between the O2k-chambers.
- »Different O2 fluxes in left and right chamber«
- communicated by »Timon-Gomez Alba« and »Baglivo Eleonora«

May-28 Tu

May-29 We

May-30 Th

"Harmonization of isolation protocols yielding intact and enzymatically active mitochondria are critical to assess mitochondrial respiratory function"

- »MiPNet20.06 Isolation mouse heart mitochondria«
- communicated by »Cardoso Luiza« and »Leo Elettra«

May-31 Fr

Next Week

2024 Week 23

Jun-03 Mo

Jun-04 Tu

Jun-05 We

Jun-06 Th

"Silencing of mt-tRF-Leu^TAA in islet cells limits the inner mitochondrial membrane potential and impairs mitochondrial oxidative phosphorylation."

Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R (2024) The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion. »Bioblast link«

from the O2k-Network »CH Lausanne Place N«

Jun-07 Fr

@@ Line 1: / Line 1: @@
 {{Template:Science for Ukraine}}
-Week 04
-* '''Jan-22 Mo'''
+Week 22
+* '''May-27 Mo'''
 :{|
-| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
+| width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Yellow-take care.png|25px|Info: take care]]
-|''' ''“We are truly glad to have your continued support and partnership.”'''''<br>
+|'''Same experimental conditions, but different O<sub>2</sub> fluxes in the left and right chambers?'''<br>
-'''[[Lu Amelia]]''' from the O2k-Network Lab  »[[TW Taoyuan Sunpoint]]«<br>
+Check for instrumental and operational factors that could be causing O<sub>2</sub> flux differences between the O2k-chambers.
-- »'''[https://wiki.oroboros.at/index.php/O2k-Feedback#More_O2k-Feedback| O2k-Feedback]'''«<br>
+<br>
+- »'''[[Different O2 fluxes in left and right chamber]]'''«<br>
+- communicated by »[[Timon-Gomez Alba]]« and »[[Baglivo Eleonora]]«
 |}
 ----
-* '''Jan-23 Tu'''
+* '''May-28 Tu'''
 ----
-* '''Jan-24 We'''
+* '''May-29 We'''
 ----
-* '''Jan-25 Th'''
+* '''May-30 Th'''
 :{|
 | width="110" align="center" | [[Image:O2k-Support.jpg|60px|link=http://wiki.oroboros.at/index.php/O2k-Open_Support |O2k-Open Support]][[File:Blue-info.png|25px|Info: improve]]
-|'''How do I view and change the settings of a measurement/file in DatLab 8?'''<br>
+|''' "Harmonization of isolation protocols yielding intact and enzymatically active mitochondria are critical to assess mitochondrial respiratory function"'''<br>
-"O2k control (active) will always show the settings of the active recording [and allow changes], while O2k info (view) will show the settings of the recorded selected file."<br>
+- »'''[[MiPNet20.06_IsolationMouseHeart-mt|MiPNet20.06 Isolation mouse heart mitochondria]]'''«<br>
+- communicated by »[[Cardoso Luiza]]« and »[[Leo Elettra]]«
--»'''[[MiPNet28.07 NextGen-O2k Series XB manual]]'''«; »'''[[MiPNet28.08 Oroboros O2k Series J manual]]'''«<br>
-- communicated by »[[Baglivo Eleonora]]« and »[[Grings Mateus]]«
 |}
 ----
-* '''Jan-26 Fr'''
+* '''May-31 Fr'''
 ----
 '''<big>Next Week</big>'''
-Week 05
+Week 23
-* '''Jan-29 Mo'''
+* '''Jun-03 Mo'''
-:{|
-| width="110" align="center" | [[File:MitoPedia.jpg|left|80px|MitoPedia|link=MitoPedia]]
-|''' Can the S-pathway O<sub><small>2</small></sub> flux be derived by subtracting N-pathway O<sub><small>2</small></sub> flux from NS-pathway O<sub><small>2</small></sub> flux?'''<br>
-No, the sum of the O<sub><small>2</small></sub> fluxes measured in the presence of NADH-linked substrates alone and succinate as the single substrate is typically higher than using a combination of all these substrates. This effect is described as incomplete additivity: <br>
-- »'''[[Additive effect of convergent electron flow]]'''« <br>
-- communicated by »[[Cardoso Luiza]]« and »[[Grings Mateus]]«
-|}
 ----
-* '''Jan-30 Tu'''
+* '''Jun-04 Tu'''
 ----
-* '''Jan-31 We'''
+* '''Jun-05 We'''
 ----
-* '''Feb-01 Th'''
+* '''Jun-06 Th'''
 :{|
-| width="110" align="center" | [[Image:O2k-Feedback.jpg|60px|link=https://wiki.oroboros.at/index.php/O2k-Feedback |O2k-Feedback]]
+| width="100" align="center" |[[Image:O2k-Publications.jpg|70px|link=http://wiki.oroboros.at/index.php/O2k-Publications:_Topics |O2k-Publications in the MiPMap]]
-|''' ''“Doing the entire hands-on module from start to finish was the best for really “cementing” theory and hands-on application together.”'''''<br>
+|'''"Silencing of mt-tRF-Leu<sup>TAA</sup> in islet cells limits the inner mitochondrial membrane potential and impairs mitochondrial oxidative phosphorylation."''' <br>
-[[Cosgrove Richard]] from Eli Lilly Research Labs, on what he liked best on [[IOC162]]<br>
+* Jacovetti C, Donnelly C, Menoud V, Suleiman M, Cosentino C, Sobel J, Wu K, Bouzakri K, Marchetti P, Guay C, Kayser B, Regazzi R (2024) The mitochondrial tRNA-derived fragment, mt-tRF-LeuTAA, couples mitochondrial metabolism to insulin secretion. [[Jacovetti 2024 Mol Metab|»Bioblast link«]]
-- »'''[[O2k-Feedback]]'''«<br>
+:from the O2k-Network »[[CH Lausanne Place N]]«
 |}
 ----
-* '''Feb-02 Fr'''
+* '''Jun-07 Fr'''
 ----