CH Basel Eckert A

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Oroboros Instruments

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CH Basel Eckert A

Oroboros O2k-Network

O2k-Network
O2k-Network Lab Psychiatrische Universitätsklinik

Neurobiologisches Labor

Address Wilhelm Klein-Str. 27, 4025
City Basel
State/Prov
Country Switzerland
Weblink
Contact Eckert Anne
Team Baysang Ginette, Ittner LM, Lim YA, Meier Fides, Rhein Virgine, Schwarz Dennis
Team previous
Status O2k 2005-
Oroboros Events MiPschool 2007, IOC35, IOC31
Topics Alzheimer's disease (AD)


O2k-Publications

 PublishedReference
Derungs 2017 Mol Psychiatry2017Derungs R, Camici GG, Spescha RD, Welt T, Tackenberg C, Späni C, Wirth F, Grimm A, Eckert A, Nitsch RM, Kulic L (2017) Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer's disease. Mol Psychiatry 22:605-14.
Hirzel 2013 J Recept Signal Transduct Res2013Hirzel E, Lindinger PW, Maseneni S, Giese M, Rhein VV, Eckert A, Hoch M, Krähenbühl S, Eberle AN (2013) Differential modulation of ROS signals and other mitochondrial parameters by the antioxidants MitoQ, resveratrol and curcumin in human adipocytes. J Recept Signal Transduct Res 33:304-12.
Leuner 2012 Mol Neurobiol2012Leuner K, Schulz K, Schütt T, Pantel J, Prvulovic D, Rhein V, Savaskan E, Czech C, Eckert A, Müller WE (2012) Peripheral mitochondrial dysfunction in Alzheimer's disease: focus on lymphocytes. Mol Neurobiol 46:194-204.
Lim 2011 PloS One2011Lim YA, Grimm A, Giese M, Mensah-Nyagan AG, Villafranca JE, Ittner LM, Eckert A, Götz J (2011) Inhibition of the mitochondrial enzyme ABAD restores the amyloid-β-mediated deregulation of estradiol. PloS One 6:e28887.
Rhein 2010 PloS One2010Rhein V, Giese M, Baysang G, Meier F, Rao S, Schulz KL, Hamburger M, Eckert A (2010) Ginkgo biloba extract ameliorates oxidative phosphorylation performance and rescues abeta-induced failure. PloS One 5:e12359.
Lim 2010 Proteomics2010Lim YA, Rhein V, Baysang G, Meier F, Poljak A, Raftery MJ, Guilhaus M, Ittner LM, Eckert A, Goetz J (2010) Abeta and human amylin share a common toxicity pathway via mitochondrial dysfunction. Proteomics 10:1621-33.
Rhein 2009 Proc Natl Acad Sci U S A2009Rhein V, Song X, Wiesner A, Ittner LM, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Savaskan E, Czech C, Götz J, Eckert A (2009) Amyloid-beta and tau synergistically impair the oxidative phosphorylation system in triple transgenic Alzheimer's disease mice. Proc Natl Acad Sci U S A 106:20057-62.
Hauptmann 2009 Neurobiol Aging2009Hauptmann S, Scherping I, Dröse S, Brandt U, Schulz KL, Jendrach M, Leuner K, Eckert A, Müller WE (2009) Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice. Neurobiol Aging 30:1574-86.
Rhein 2009 Cell Mol Neurobiol2009Rhein V, Baysang G, Rao S, Meier F, Bonert A, Müller-Spahn F, Eckert A (2009) Amyloid-beta leads to impaired cellular respiration, energy production and mitochondrial electron chain complex activities in human neuroblastoma cells. Cell Mol Neurobiol 29:1063-71.
Eckert 2008 J Mol Med2008Eckert A, Hauptmann S, Scherping I, Meinhardt J, Rhein V, Dröse S, Brandt U, Fändrich M, Müller WE, Götz J (2008) Oligomeric and fibrillar species of beta-amyloid (Abeta42) both impair mitochondrial function in P301L tau transgenic mice. J Mol Med 86:1255-67.
Rhein 2008 Alzh Dement2008Rhein V, Baysang G, Meier F, Ozmen L, Bluethmann H, Dröse S, Brandt U, Müller-Spahn F, Czech C, Goetz J, Eckert A (2008) P2-140: Mitochondrial failure in a transgenic mice model of Alzheimer's disease with plaques and tangles. Alzh Dement 4 Suppl: T411
David 2005 J Biol Chem2005David DC, Hauptmann S, Scherping I, Schuessel K, Keil U, Rizzu P, Ravid R, Dröse S, Brandt U, Muller WE, Eckert A, Götz J (2005) Proteomic and functional analysis reveal a mitochondrial dysfunction in P301L tau transgenic mice. J Biol Chem 280:23802-14.

O2k-Abstracts

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