Difference between revisions of "Comelli 2011 Mitochondrion"
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{{Publication | {{Publication | ||
|title=Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I (2011) Cardiac differentiation promotes mitochondria development and ameliorates oxidative capacity in H9c2 cardiomyoblasts. Mitochondrion 11: 315- | |title=Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I (2011) Cardiac differentiation promotes mitochondria development and ameliorates oxidative capacity in H9c2 cardiomyoblasts. Mitochondrion 11:315-26. | ||
|info=[http://www.ncbi.nlm.nih.gov/pubmed?term=Comelli%20M%20mitochondria%202010 PMID:202010] | |info=[http://www.ncbi.nlm.nih.gov/pubmed?term=Comelli%20M%20mitochondria%202010 PMID: 202010] | ||
|authors=Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I | |authors=Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I | ||
|year=2011 | |year=2011 | ||
|journal=Mitochondrion | |journal=Mitochondrion | ||
|abstract=H9c2 undergoing cardiac differentiation induced by all-trans-retinoic acid were investigated for mitochondria structural features together with the implied functional changes, as a model for the study of mitochondrial development in cardiogenic progenitor cells. As the expression of cardiac markers became detectable, mitochondrial mass increased and mitochondrial morphology and ultrastructure changed. Reticular network organization developed and more bulky mitochondria with greater numbers of closely packed cristae and more electron-dense matrix were detected. Increased expression of PGC-1Ξ± proved the occurrence of mitochondrial biogenesis. Improvements in mitochondrial energetic competence were also documented, linked to better assembly between F(0) and F(1) sectors of the F(0)F(1)ATPsynthase enzyme complex. | |abstract=H9c2 undergoing cardiac differentiation induced by all-trans-retinoic acid were investigated for mitochondria structural features together with the implied functional changes, as a model for the study of mitochondrial development in cardiogenic progenitor cells. As the expression of cardiac markers became detectable, mitochondrial mass increased and mitochondrial morphology and ultrastructure changed. Reticular network organization developed and more bulky mitochondria with greater numbers of closely packed cristae and more electron-dense matrix were detected. Increased expression of [[PGC-1Ξ±]] proved the occurrence of mitochondrial biogenesis. Improvements in mitochondrial energetic competence were also documented, linked to better assembly between F(0) and F(1) sectors of the F(0)F(1)ATPsynthase enzyme complex. | ||
|mipnetlab= | |mipnetlab=IT Udine Grassi B, IT Udine Mavelli I | ||
}} | }} | ||
{{Labeling | {{Labeling | ||
|tissues=Heart | |||
|instruments=Oxygraph-2k | |instruments=Oxygraph-2k | ||
}} | }} | ||
Latest revision as of 16:08, 19 March 2015
| Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I (2011) Cardiac differentiation promotes mitochondria development and ameliorates oxidative capacity in H9c2 cardiomyoblasts. Mitochondrion 11:315-26. |
Β» PMID: 202010
Comelli M, Domenis R, Bisetto E, Contin M, Marchini M, Ortolani F, Tomasetig L, Mavelli I (2011) Mitochondrion
Abstract: H9c2 undergoing cardiac differentiation induced by all-trans-retinoic acid were investigated for mitochondria structural features together with the implied functional changes, as a model for the study of mitochondrial development in cardiogenic progenitor cells. As the expression of cardiac markers became detectable, mitochondrial mass increased and mitochondrial morphology and ultrastructure changed. Reticular network organization developed and more bulky mitochondria with greater numbers of closely packed cristae and more electron-dense matrix were detected. Increased expression of PGC-1Ξ± proved the occurrence of mitochondrial biogenesis. Improvements in mitochondrial energetic competence were also documented, linked to better assembly between F(0) and F(1) sectors of the F(0)F(1)ATPsynthase enzyme complex.
β’ O2k-Network Lab: IT Udine Grassi B, IT Udine Mavelli I
Labels:
Tissue;cell: Heart
HRR: Oxygraph-2k
