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O2k Applications

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O2k Applications

High-Resolution Respirometry (HRR): O2k-Applications

  • Diagnosis of acquired and genetic mitochondrial diseases
  • Diagnosis of myopathies and neuromuscular pathologies
  • Studies on cell function and cell death - apoptosis and necrosis
  • Oxidative stress
  • Ischemia-reperfusion injury
  • Aging and senescence
  • Pharmacological tests


For more applications, browse through the O2k-Publications


High-Resolution: high accuracy, minimum amount of sample

Sample Amount O2k-Chamber Temp.
Heart mitochondria 0.01 mg protein 2.0 ml 37 Β° C
Permeabilized muscle fibers 1 mg wet weight 2.0 ml 37 Β° C
Endothelial cells 0.2 β€’ 10^6 cells 2.0 ml 37 Β° C
T-lymphocytes 1 β€’ 10^6 cells 2.0 ml 37 Β° C

Reference: Pesta 2012 Methods Mol Biol