Difference between revisions of "Superoxide dismutase"
From Bioblast
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{{MitoPedia | {{MitoPedia | ||
|abbr=SOD | |abbr=SOD | ||
|description=Mammalian '''superoxide dismutase''' (SOD) exists in three forms, of which the | |description=Mammalian '''superoxide dismutase''' (SOD) exists in three forms, of which the Mn-SOD occurs in mitochondria (mtSOD, SOD2; 93 kD homotetramer) and many bacteria, in contrast to the Cu-Zn forms of SOD (cytosolic SOD1, extracellular SOD3 anchored to the extracellular matrix and cell surface). [[Superoxide]] anion (O<sub>2</sub><sup>•-</sup>) is a major [[reactive oxygen species]] (ROS) which is dismutated by SOD to [[oxygen]] and [[hydrogen peroxide | H<sub>2</sub>O<sub>2</sub>]]. | ||
|info=[[Fridovich_1997_J Biol Chem]] | |info=[[Fridovich_1997_J Biol Chem]] | ||
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== Application in [[fluorometry]] == | == Application in [[fluorometry]] == | ||
* [[Amplex_red| | * Add SOD for [[Amplex_red | measurement of H<sub>2</sub>O<sub>2</sub> with Amplex Red]]. | ||
Revision as of 03:45, 16 April 2014
- high-resolution terminology - matching measurements at high-resolution
Superoxide dismutase
Description
Mammalian superoxide dismutase (SOD) exists in three forms, of which the Mn-SOD occurs in mitochondria (mtSOD, SOD2; 93 kD homotetramer) and many bacteria, in contrast to the Cu-Zn forms of SOD (cytosolic SOD1, extracellular SOD3 anchored to the extracellular matrix and cell surface). Superoxide anion (O2•-) is a major reactive oxygen species (ROS) which is dismutated by SOD to oxygen and H2O2.
Abbreviation: SOD
Reference: Fridovich_1997_J Biol Chem
MitoPedia topics: Enzyme
Application in fluorometry
- Add SOD for measurement of H2O2 with Amplex Red.
