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TPP+ inhibitory effect

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high-resolution terminology - matching measurements at high-resolution


TPP+ inhibitory effect

Description

A major first task in establishing a system for measurement of membrane potential using probe molecules is the evaluation of inhibitory concentrations of the probe molecule on the activity of respiration. This important 'side effect' of TPP+ and TPMP+ (and various dyes) is frequently ignored. Accurate knowledge of a threshold concentration is required to evaluate the necessary limit of detection of TPP+, and for restriction of experimental TPP+ concentrations below the inhibitory range MiPNet14.05.


Reference: MiPNet14.05


Labels:




Regulation: Respiration; OXPHOS; ETS Capacity"Respiration; OXPHOS; ETS Capacity" is not in the list (Aerobic glycolysis, ADP, ATP, ATP production, AMP, Calcium, Coupling efficiency;uncoupling, Cyt c, Flux control, Inhibitor, ...) of allowed values for the "Respiration and regulation" property. 


HRR: MultiSensor pH; TPP; NO"MultiSensor pH; TPP; NO" is not in the list (Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, O2k-Spectrophotometer, O2k-Manual, O2k-Protocol, ...) of allowed values for the "Instrument and method" property., Chemicals; Media"Chemicals; Media" is not in the list (Oxygraph-2k, TIP2k, O2k-Fluorometer, pH, NO, TPP, Ca, O2k-Spectrophotometer, O2k-Manual, O2k-Protocol, ...) of allowed values for the "Instrument and method" property. 


MiPNet14.05